Page last updated: 2024-08-18

chalcone and Reperfusion Injury

chalcone has been researched along with Reperfusion Injury in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.85)18.2507
2000's4 (15.38)29.6817
2010's15 (57.69)24.3611
2020's6 (23.08)2.80

Authors

AuthorsStudies
Guohua, F; Juan, X; Wei, W; Zhongyin, Z1
Du, Y; He, Y; Li, C; Wan, H; Xu, S; Yang, J1
Cai, YF; Fan, LL; Fang, H; Lu, FM; Ma, HH; Qiao, LJ; Su, S; Wan, C; Wen, JR; Wu, GL; Zhang, C; Zhang, SJ; Zhou, ZY1
Chao, M; Gao, C; Huang, Y1
Chen, L; Gao, F; Li, Y; Sun, B; Wang, H; Wu, J; Yan, Z; Yang, X; Zhang, P1
Chang, D; Huang, P; Seto, S; Wang, N; Wu, SP1
Deng, L; He, Y; Wan, H; Yu, L; Zhou, H1
Chang, D; Liang, H; Seto, SW; Wang, N; Yang, G1
Bai, J; Cheng, L; Cui, D; Gao, K; Jia, Y; Li, L; Li, S; Song, Y; Wang, F; Wang, J; Wen, A; Zhao, J1
Cui, J; Ding, Y; Dou, F; Fei, F; Liu, T; Ma, J; Su, N; Wang, W; Wen, A; Xu, H; Yang, L; Yang, Z1
Cao, J; Chen, S; Liu, W; Luo, X; Qiao, Y; Sun, M; Wen, A; Yang, Z; Zhao, X1
Chen, L; Kong, L; Liu, H; Sun, B; Wei, X; Xiang, Y; Zhang, X1
Dai, P; Huang, W; Liu, B; Ma, S; Xiao, X; Zhou, D1
Dong, W; Ji, X; Liu, KJ; Luo, Y; Qi, Z; Shen, J; Shi, W; Yan, F; Zhang, C; Zhao, Y1
Bai, X; Jiang, S; Li, C; Ma, C; Shi, Z; Wang, C1
Ramagiri, S; Taliyan, R1
Chen, X; Fu, L; Lv, Y; Qian, Y; Wei, X; Zhong, H1
Min, J; Wei, C1
Gao, WY; Ye, SY1
Qu, S; Sun, X; Wei, X; Zhang, X; Zhao, Y1
Fan, QY; Ma, BA; Ma, S; Qiu, XC; Ren, PC; Shan, LQ; Wang, YC; Zhang, Y; Zheng, LH; Zhou, Y1
Cheng, Y; Han, J; Liang, H; Sun, L; Xu, YW; Yang, L; Zhao, RJ1
An, J; Ding, H; Fu, F; Liu, H; Sun, X; Wang, J; Wei, X; Zhang, X1
Yang, J; Zhan, C1
Kondo, M; Naito, Y; Nakamura, S; Takahashi, S; Yoshikawa, T1
Cotelle, N; Lebeau, J; Neviere, R1

Other Studies

26 other study(ies) available for chalcone and Reperfusion Injury

ArticleYear
Isoliquiritin apioside relieves intestinal ischemia/reperfusion-induced acute lung injury by blocking Hif-1α-mediated ferroptosis.
    International immunopharmacology, 2022, Volume: 108

    Topics: Acute Lung Injury; Animals; Chalcone; Ferroptosis; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Mice; Reperfusion Injury; RNA, Messenger

2022
LC-MS/MS combined with blood-brain dual channel microdialysis for simultaneous determination of active components of astragali radix-safflower combination and neurotransmitters in rats with cerebral ischemia reperfusion injury: Application in pharmacokine
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 106

    Topics: Animals; Aspartic Acid; Astragalus Plant; Blood-Brain Barrier; Carthamus tinctorius; Chalcone; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dopamine; Drugs, Chinese Herbal; gamma-Aminobutyric Acid; Glucosides; Glutamates; Microdialysis; Neurotransmitter Agents; Phenylpropionates; Quinones; Rats; Reperfusion Injury; Saponins; Serotonin; Tandem Mass Spectrometry; Triterpenes

2022
Hydroxysafflor Yellow A Exerts Neuroprotective Effect by Reducing Aβ Toxicity Through Inhibiting Endoplasmic Reticulum Stress in Oxygen-Glucose Deprivation/Reperfusion Cell Model.
    Rejuvenation research, 2023, Volume: 26, Issue:2

    Topics: Amyloid Precursor Protein Secretases; Apoptosis; Aspartic Acid Endopeptidases; Chalcone; Endoplasmic Reticulum Stress; Glucose; Humans; Neuroblastoma; Neuroprotective Agents; Oxygen; Quinones; Reperfusion; Reperfusion Injury; Stroke

2023
Xanthoangelol alleviates cerebral ischemia reperfusion injury in rats.
    Anatomical record (Hoboken, N.J. : 2007), 2021, Volume: 304, Issue:3

    Topics: Animals; Apoptosis; Astrocytes; Cell Survival; Chalcone; Female; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury

2021
Protective effect of Hydroxysafflor Yellow A on cerebral ischemia reperfusion-injury by regulating GSK3β-mediated pathways.
    Neuroscience letters, 2020, 09-25, Volume: 736

    Topics: Animals; Apoptosis; Brain; Brain Ischemia; Chalcone; Glycogen Synthase Kinase 3 beta; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Quinones; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction

2020
Hydroxysafflor yellow A alleviates cerebral ischemia reperfusion injury by suppressing apoptosis via mitochondrial permeability transition pore.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 85

    Topics: Animals; Apoptosis; Brain Ischemia; Chalcone; Endothelial Cells; Male; MAP Kinase Signaling System; Mitochondria; Mitochondrial Permeability Transition Pore; Phosphorylation; Quinones; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2021
Protective effect of hydroxysafflor yellow A alone or in combination with acetylglutamine on cerebral ischemia reperfusion injury in rat: A PET study using
    European journal of pharmacology, 2018, Apr-15, Volume: 825

    Topics: Animals; Apoptosis; Brain Ischemia; Chalcone; Fluorine Radioisotopes; Glutamine; Infarction, Middle Cerebral Artery; Inflammation; Male; Neuroprotective Agents; Positron-Emission Tomography; Quinones; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Up-Regulation

2018
Hydroxysafflor yellow a protects brain microvascular endothelial cells against oxygen glucose deprivation/reoxygenation injury: Involvement of inhibiting autophagy via class I PI3K/Akt/mTOR signaling pathway.
    Brain research bulletin, 2018, Volume: 140

    Topics: Animals; Autophagy; Brain; Cell Hypoxia; Cell Survival; Cells, Cultured; Chalcone; Dose-Response Relationship, Drug; Endothelial Cells; Glucose; Microvessels; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Quinones; Rats, Sprague-Dawley; Reperfusion Injury; TOR Serine-Threonine Kinases

2018
Protective effect of hydroxysafflor yellow A against acute kidney injury via the TLR4/NF-κB signaling pathway.
    Scientific reports, 2018, 06-15, Volume: 8, Issue:1

    Topics: Acute Kidney Injury; Animals; Chalcone; Cytokines; Quinones; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4; Transcription Factor RelA

2018
Proteomic Analysis of Hydroxysafflor Yellow A Against Cerebral Ischemia/Reperfusion Injury in Rats.
    Rejuvenation research, 2019, Volume: 22, Issue:6

    Topics: Animals; Brain Ischemia; Chalcone; Male; Neuroprotective Agents; Proteome; Proteomics; Quinones; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction

2019
Neuroprotection of hydroxysafflor yellow A in experimental cerebral ischemia/reperfusion injury via metabolic inhibition of phenylalanine and mitochondrial biogenesis.
    Molecular medicine reports, 2019, Volume: 19, Issue:4

    Topics: Animals; Behavior, Animal; Brain Ischemia; Chalcone; Disease Models, Animal; Energy Metabolism; Gene Expression Regulation, Enzymologic; Mice; Mitochondria; Neurons; Neuroprotective Agents; Organelle Biogenesis; Oxidative Stress; PC12 Cells; Phenylalanine; Quinones; Rats; Reperfusion Injury; Treatment Outcome

2019
Hydroxysafflor yellow A protects against cerebral ischemia-reperfusion injury by anti-apoptotic effect through PI3K/Akt/GSK3β pathway in rat.
    Neurochemical research, 2013, Volume: 38, Issue:11

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Chalcone; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Quinones; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction

2013
The effect of safflower yellow on spinal cord ischemia reperfusion injury in rabbits.
    Oxidative medicine and cellular longevity, 2013, Volume: 2013

    Topics: Animals; Anterior Horn Cells; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Shape; Chalcone; Hindlimb; In Situ Nick-End Labeling; Interleukin-8; Male; Malondialdehyde; Phytotherapy; Rabbits; Reperfusion Injury; Spinal Cord Ischemia; Superoxide Dismutase; Time Factors; Vital Signs

2013
AKT-related autophagy contributes to the neuroprotective efficacy of hydroxysafflor yellow A against ischemic stroke in rats.
    Translational stroke research, 2014, Volume: 5, Issue:4

    Topics: Animals; Autophagy; Brain; Brain Ischemia; Chalcone; Infarction, Middle Cerebral Artery; Male; Motor Activity; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-akt; Quinones; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke

2014
Hydroxysafflor yellow A attenuates ischemia/reperfusion-induced liver injury by suppressing macrophage activation.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Chalcone; Chemotaxis; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation Mediators; Liver; Liver Diseases; Macrophage Activation; Macrophages; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Quinones; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Time Factors

2014
Neuroprotective effect of hydroxy safflor yellow A against cerebral ischemia-reperfusion injury in rats: putative role of mPTP.
    Journal of basic and clinical physiology and pharmacology, 2016, Volume: 27, Issue:1

    Topics: Animals; Brain Ischemia; Chalcone; Cognition Disorders; Disease Models, Animal; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Male; Maze Learning; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neuroprotective Agents; Oxidative Stress; Quinones; Rats; Rats, Wistar; Reperfusion Injury; Tumor Necrosis Factor-alpha

2016
Hydroxysafflor yellow A exerts neuroprotective effects in cerebral ischemia reperfusion-injured mice by suppressing the innate immune TLR4-inducing pathway.
    European journal of pharmacology, 2015, Dec-15, Volume: 769

    Topics: Animals; Brain-Derived Neurotrophic Factor; Chalcone; Immunity, Innate; Infarction, Middle Cerebral Artery; Mice; Mitogen-Activated Protein Kinases; Neuroprotective Agents; NF-kappa B; Quinones; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4; Up-Regulation

2015
Hydroxysafflor yellow A cardioprotection in ischemia-reperfusion (I/R) injury mainly via Akt/hexokinase II independent of ERK/GSK-3β pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 87

    Topics: Animals; Apoptosis; Caspase 3; Cell Line; Chalcone; Glycogen Synthase Kinase 3 beta; Hexokinase; MAP Kinase Signaling System; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Protective Agents; Proto-Oncogene Proteins c-akt; Quinones; Rats; Reperfusion Injury; Signal Transduction; Up-Regulation

2017
Hydroxysafflor yellow A protects neuron against hypoxia injury and suppresses inflammatory responses following focal ischemia reperfusion in rats.
    Archives of pharmacal research, 2008, Volume: 31, Issue:8

    Topics: Animals; Behavior, Animal; Blotting, Western; Brain Edema; Cell Hypoxia; Cells, Cultured; Chalcone; Female; Glucose; Indicators and Reagents; Inflammation; Interleukin-1beta; Ischemic Attack, Transient; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Nitric Oxide; Pregnancy; Quinones; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha

2008
Hydroxysafflor Yellow A suppresses thrombin generation and inflammatory responses following focal cerebral ischemia-reperfusion in rats.
    Bioorganic & medicinal chemistry letters, 2010, Jul-15, Volume: 20, Issue:14

    Topics: Animals; Brain Ischemia; Chalcone; Inflammation; Male; Quinones; Rats; Rats, Wistar; Reperfusion Injury; Thrombin

2010
Hydroxysafflor Yellow A protects spinal cords from ischemia/reperfusion injury in rabbits.
    BMC neuroscience, 2010, Aug-13, Volume: 11

    Topics: Animals; Apoptosis; Chalcone; In Situ Nick-End Labeling; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Quinones; Rabbits; Reperfusion Injury; Spinal Cord Injuries; Spinal Cord Ischemia; Superoxide Dismutase

2010
Neuroprotection of hydroxysafflor yellow A in the transient focal ischemia: inhibition of protein oxidation/nitration, 12/15-lipoxygenase and blood-brain barrier disruption.
    Brain research, 2012, Sep-14, Volume: 1473

    Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Blood-Brain Barrier; Blotting, Western; Chalcone; Disease Models, Animal; Fluorescent Antibody Technique; Ischemic Attack, Transient; Male; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Quinones; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2012
Hydroxysafflor yellow A protects rat brains against ischemia-reperfusion injury by antioxidant action.
    Neuroscience letters, 2005, Sep-23, Volume: 386, Issue:1

    Topics: Animals; Antioxidants; Brain; Cerebral Infarction; Chalcone; Disease Models, Animal; Free Radical Scavengers; Ischemic Attack, Transient; Malondialdehyde; Molecular Structure; Neuroprotective Agents; Oxidative Stress; Quinones; Rats; Reperfusion Injury; Superoxide Dismutase; Treatment Outcome

2005
Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats.
    Pharmacological research, 2006, Volume: 53, Issue:3

    Topics: Adenine Nucleotides; Animals; Antioxidants; Brain; Brain Edema; Brain Ischemia; Catalase; Chalcone; Chalcones; Disease Models, Animal; Dose-Response Relationship, Drug; Glycyrrhiza; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Plant Roots; Premedication; Rats; Reperfusion Injury; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase

2006
Effect of sofalcone on gastric mucosal injury induced by ischemia-reperfusion and its antioxidant properties.
    Journal of clinical gastroenterology, 1993, Volume: 17 Suppl 1

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Capillaries; Chalcone; Chalcones; Electron Spin Resonance Spectroscopy; Gastric Mucosa; Ischemia; Lipid Peroxidation; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Superoxides

1993
Beneficial effects of different flavonoids, on functional recovery after ischemia and reperfusion in isolated rat heart.
    Bioorganic & medicinal chemistry letters, 2001, Jan-08, Volume: 11, Issue:1

    Topics: Allopurinol; Animals; Catalase; Chalcone; Flavones; Flavonoids; Glutathione Peroxidase; Heart; In Vitro Techniques; Lipid Peroxidation; Male; Molecular Structure; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rutin; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Ventricular Pressure

2001