chalcone has been researched along with Lung Neoplasms in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 5 (20.83) | 29.6817 |
| 2010's | 12 (50.00) | 24.3611 |
| 2020's | 5 (20.83) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, TE; Lad, R; Srinivasan, B; Xing, C | 1 |
| Baginski, M; Cekala, K; Dzierzynska, M; Jurasz, J; Maciejewska, N; Olszewski, M; Serocki, M; Wieczerzak, E | 1 |
| Fang, WS; Liu, J; Lv, G; Niu, S; Wang, H; Wang, N; Zhang, G | 1 |
| Challagundla, N; Mishra, S; Patel, S; Rajput, RA | 1 |
| Akgun, O; Ari, F; Aydin, I; Coskun, D; Erturk, E; Onur, OE | 1 |
| Liu, GY; Mu, WW; Yang, J | 1 |
| Fan, A; Ge, D; Liu, L; Ma, L; Ma, Y; Song, C; Wang, X; Xie, H; Xu, Y; Yu, X; Zhang, Q | 1 |
| Bai, X; Dong, N; Li, H; Li, X; Liu, X; Wang, L; Yang, B; Zhang, S; Zhang, Y; Zhao, T | 1 |
| Bao, M; Chen, L; Chen, Q; Jiang, C; Jiang, L; Jiang, X; Li, W; Qiu, P; Qiu, Y; Wang, J; Wei, X; Wu, J; Xie, J; Zhou, X; Zhu, M | 1 |
| Batko, B; Du, X; Geller, DS; Gill, J; Gorlick, R; Hoang, BH; Koirala, P; Liu, Y; O'Donnell, EF; Piperdi, S; Ren, T; Roth, M; Sato, K; Wang, J; Yang, R; Zaphiros, N; Zhang, J; Zhang, W; Zhang, Y; Zheng, D; Zi, X; Zvi, YS | 1 |
| An, Q; Jiang, M; Xu, N; Zhou, LY | 1 |
| Cao, C; Liu, X; Su, L; Xu, L; Yang, L; Zhong, D | 1 |
| Ho, WS; Zhou, Y | 1 |
| Bedi, PM; Jain, S; Kumar, D; Kumar, S; Malik, F; Nepali, K | 1 |
| Jeong, JH; Kwon, TK; Oh, YJ; Seo, YH | 1 |
| Fu, H; Li, Y; Shou, Q; Tang, X; Tu, J; Wang, J; Wu, R; Zhang, L; Zhou, W | 1 |
| Hecht, SS; Hermanson, D; Johnson, TE; Kassie, F; Lu, J; O'Sullivan, MG; Upadhyaya, P; Wang, L; Xing, C | 1 |
| Charlson, AT; Solberg, EL; Srinivasan, B; Warmka, JK; Wattenberg, EV; Xing, C; Zeliadt, NA | 1 |
| Baba, K; Kimura, Y | 1 |
| Baba, M; Ii, T; Katoh, D; Kitamura, N; Nishino, H; Okuyama, T; Satomi, Y; Shimada, J | 1 |
| Chiang, LC; Hsu, YL; Kuo, PL; Lin, CC | 1 |
| Coccia, JB; Galbraith, AR; Wattenberg, LW | 1 |
| Wattenberg, L | 1 |
| Baba, M; Endo, H; Hamamoto, T; Joichi, Y; Kaneko, S; Morita, T; Nishino, H; Okada, Y; Okuyama, T; Tokue, A; Yamazaki, S | 1 |
1 review(s) available for chalcone and Lung Neoplasms
| Article | Year |
|---|---|
Chalcones, myo-inositol and other novel inhibitors of pulmonary carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Chalcone; Chalcones; Dexamethasone; Female; Inositol; Lung Neoplasms; Mice; Mice, Inbred A; Plant Oils | 1995 |
23 other study(ies) available for chalcone and Lung Neoplasms
| Article | Year |
|---|---|
Structure-activity relationship studies of chalcone leading to 3-hydroxy-4,3',4',5'-tetramethoxychalcone and its analogues as potent nuclear factor kappaB inhibitors and their anticancer activities.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chalcone; Chalcones; Female; Genes, Reporter; Humans; I-kappa B Kinase; Inhibitory Concentration 50; Interleukin-1 Receptor-Associated Kinases; Luciferases; Lung Neoplasms; Mice; Mice, Nude; NF-kappa B; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2009 |
Novel chalcone-derived pyrazoles as potential therapeutic agents for the treatment of non-small cell lung cancer.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Pyrazoles; Structure-Activity Relationship; Tubulin | 2022 |
Structure Modification of FXR Antagonistic Chalcones and Their Inhibitory Effects on NSCLC Cell Proliferation and Metastasis.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Chalcone; Chalcones; Humans; Lung Neoplasms; Receptors, Cytoplasmic and Nuclear | 2022 |
Design, synthesis, characterization and anticancer activity evaluation of deoxycholic acid-chalcone conjugates.
Topics: Antineoplastic Agents; Bile Acids and Salts; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Deoxycholic Acid; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Structure-Activity Relationship | 2022 |
Targeting the epithelial-mesenchymal transition (EMT) pathway with combination of Wnt inhibitor and chalcone complexes in lung cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Chalcone; Chalcones; Epithelial-Mesenchymal Transition; Humans; Lung; Lung Neoplasms; Niclosamide | 2023 |
Synthesis and evaluation of the anticancer activity of bischalcone analogs in human lung carcinoma (A549) cell line.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Chalcone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Lung Neoplasms; Reactive Oxygen Species | 2020 |
The Role of E-Cadherin/β-Catenin in Hydroxysafflor Yellow A Inhibiting Adhesion, Invasion, Migration and Lung Metastasis of Hepatoma Cells.
Topics: Animals; beta Catenin; Cadherins; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Chalcone; Humans; Liver Neoplasms; Lung Neoplasms; Male; Mice; Quinones | 2017 |
Apoptosis-inducing effects and growth inhibitory of a novel chalcone, in human hepatic cancer cells and lung cancer cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chalcone; Humans; Liver Neoplasms; Lung Neoplasms; Mice; Molecular Docking Simulation; Neoplasm Invasiveness; Up-Regulation; Xenograft Model Antitumor Assays | 2018 |
Design, synthesis, and evaluation of chalcone analogues incorporate α,β-Unsaturated ketone functionality as anti-lung cancer agents via evoking ROS to induce pyroptosis.
Topics: Antineoplastic Agents; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Ketones; Lung Neoplasms; Molecular Structure; Pyroptosis; Reactive Oxygen Species; Structure-Activity Relationship; Tumor Cells, Cultured | 2018 |
Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma.
Topics: Administration, Oral; Animals; Cell Line, Tumor; Cell Proliferation; Chalcone; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Osteosarcoma; Prognosis; S-Phase Kinase-Associated Proteins | 2018 |
Hydroxysafflor yellow A inhibited lipopolysaccharide-induced non-small cell lung cancer cell proliferation, migration, and invasion by suppressing the PI3K/AKT/mTOR and ERK/MAPK signaling pathways.
Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chalcone; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Lipopolysaccharides; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinones; Signal Transduction; TOR Serine-Threonine Kinases | 2019 |
The chalcone 2'-hydroxy-4',5'-dimethoxychalcone activates death receptor 5 pathway and leads to apoptosis in human nonsmall cell lung cancer cells.
Topics: Activating Transcription Factor 4; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Cycle Checkpoints; Cell Line, Tumor; Chalcone; Chalcones; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Endoplasmic Reticulum Stress; Gene Expression; Humans; Lung Neoplasms; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; Transcription Factor CHOP; Transcriptional Activation; Up-Regulation | 2013 |
Combination of liquiritin, isoliquiritin and isoliquirigenin induce apoptotic cell death through upregulating p53 and p21 in the A549 non-small cell lung cancer cells.
Topics: Aldehyde Reductase; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Chalcone; Chalcones; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Enzyme Inhibitors; Flavanones; Glucosides; Glycyrrhiza uralensis; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Plant Extracts; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
4,6-diaryl Pyrimidones as Constrained Chalcone Analogues: Design, Synthesis and Evaluation as Antiproliferative Agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chalcone; HCT116 Cells; Humans; Lung Neoplasms; Male; Membrane Potential, Mitochondrial; Prostatic Neoplasms; Pyrimidinones | 2015 |
Chalcone-templated Hsp90 inhibitors and their effects on gefitinib resistance in non-small cell lung cancer (NSCLC).
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Survival; Chalcone; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gefitinib; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Molecular Docking Simulation; Protein Structure, Secondary; Quinazolines | 2017 |
Safflower Yellow Prevents Pulmonary Metastasis of Breast Cancer by Inhibiting Tumor Cell Invadopodia.
Topics: Animals; Breast Neoplasms; Carthamus tinctorius; Chalcone; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermal Growth Factor; Female; Humans; Lung Neoplasms; Matrix Metalloproteinase 9; MCF-7 Cells; Mice; Mice, Inbred BALB C; Phytotherapy; Podosomes; Proto-Oncogene Proteins pp60(c-src) | 2016 |
Lung tumorigenesis suppressing effects of a commercial kava extract and its selected compounds in A/J mice.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents, Phytogenic; Benzo(a)pyrene; Carcinogens; Cell Death; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Female; Kava; Liver; Lung Neoplasms; Mice; Mice, Inbred Strains; Nitrosamines; Phytotherapy; Plant Extracts | 2011 |
Inhibition of mitogen activated protein kinases increases the sensitivity of A549 lung cancer cells to the cytotoxicity induced by a kava chalcone analog.
Topics: Cell Survival; Chalcone; Chalcones; Drug Resistance, Neoplasm; Humans; Kava; Lung Neoplasms; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasms | 2012 |
Antitumor and antimetastatic activities of Angelica keiskei roots, part 1: Isolation of an active substance, xanthoangelol.
Topics: Acetates; Angelica; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Adhesion; Cell Division; Chalcone; DNA Replication; DNA, Neoplasm; Endothelial Growth Factors; Endothelium, Vascular; Ethanol; Female; Fibrinolysin; Intercellular Signaling Peptides and Proteins; Liver Neoplasms; Lung Neoplasms; Lymphokines; Mice; Mice, Inbred C57BL; Molecular Structure; Plant Roots; Survival Rate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Induction of cell cycle arrest and p21(CIP1/WAF1) expression in human lung cancer cells by isoliquiritigenin.
Topics: Cell Cycle; Cell Division; Cell Line, Tumor; Chalcone; Chalcones; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Flow Cytometry; G2 Phase; Humans; Lung Neoplasms; Mitosis; Models, Chemical; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA; Time Factors; Up-Regulation | 2004 |
Isoliquiritigenin inhibits the proliferation and induces the apoptosis of human non-small cell lung cancer a549 cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; DNA Fragmentation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fas Ligand Protein; fas Receptor; Humans; Lung Neoplasms; Membrane Glycoproteins; Oncogene Protein p21(ras); Tumor Suppressor Protein p53 | 2004 |
Inhibition of carcinogen-induced pulmonary and mammary carcinogenesis by chalcone administered subsequent to carcinogen exposure.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Chalcone; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred A; Rats; Rats, Sprague-Dawley; Stomach Neoplasms | 1994 |
Isoliquiritigenin suppresses pulmonary metastasis of mouse renal cell carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Chalcone; Chalcones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorouracil; Glycyrrhiza; Kidney Neoplasms; Leukopenia; Lipopolysaccharides; Lung Neoplasms; Macrophages; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Phytotherapy; Tumor Cells, Cultured; Weight Loss | 2002 |