Page last updated: 2024-08-18

chalcone and Leucocythaemia

chalcone has been researched along with Leucocythaemia in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's4 (36.36)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Jing, Y; Li, M; Liu, D; Song, D; Tan, J; Wang, W; Yang, X; Zhao, L1
Ascenso, OS; Estévez, F; González, I; Hernández, I; Leitão, EPT; Quintana, J; Rijo, P; Santos de Almeida, T1
Abulkhair, HS; Fayed, EA; Husseiny, EM; Othman, EM1
Brouard, I; Del Rosario, H; Estévez, F; García, C; González-Santana, D; Quintana, J; Saavedra, E; Spínola-Lasso, E; Tabraue, C1
Brouard, I; Del Rosario, H; Estévez, F; Quintana, J; Saavedra, E1
Chandgude, MG; Deshpande, MV; Gample, SP; Joshi, SP; Kulkarni, RR; Sarkar, D; Tupe, SG1
Liu, H; Liu, Z; Teng, Y; Wang, H; Wang, L; Wu, M; Yu, P; Yuan, Y; Zhang, Q1
Chiaradia, LD; Creczynski-Pasa, TB; de Cordova, CA; Nunes, RJ; Winter, E; Yunes, RA1
Akihisa, T; Asami, S; Hasegawa, D; Kimura, Y; Motani, K; Nishimura, R; Suzuki, T; Tabata, K; Takayanagi, N; Ukiya, M1
Chao, LR; Elomri, A; Magiatis, P; Seguin, E; Skaltsounis, AL; Tillequin, F1
Hashimoto, Y; Kagechika, H; Kawachi, E; Shudo, K1

Other Studies

11 other study(ies) available for chalcone and Leucocythaemia

ArticleYear
Synthesis of a series of novel dihydroartemisinin derivatives containing a substituted chalcone with greater cytotoxic effects in leukemia cells.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Animals; Antineoplastic Agents; Apoptosis; Artemisinins; Cell Line, Tumor; Cell Proliferation; Chalcones; Chemistry, Pharmaceutical; Drug Design; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia; Mice; Models, Chemical

2009
Design and synthesis of naphthylchalcones as novel anti-leukaemia agents.
    Bioorganic chemistry, 2021, Volume: 117

    Topics: Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Chalcone; Drug Design; Drug Screening Assays, Antitumor; Humans; Leukemia

2021
Apoptosis induction, PARP-1 inhibition, and cell cycle analysis of leukemia cancer cells treated with novel synthetic 1,2,3-triazole-chalcone conjugates.
    Bioorganic chemistry, 2022, Volume: 123

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Drug Screening Assays, Antitumor; Humans; Leukemia; Molecular Docking Simulation; Molecular Structure; Poly(ADP-ribose) Polymerase Inhibitors; Structure-Activity Relationship; Triazoles

2022
Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells.
    Bioorganic chemistry, 2022, Volume: 127

    Topics: Amides; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Esters; HL-60 Cells; Humans; Leukemia; Leukocytes, Mononuclear; Structure-Activity Relationship

2022
6'-Benzyloxy-4-bromo-2'-hydroxychalcone is cytotoxic against human leukaemia cells and induces caspase-8- and reactive oxygen species-dependent apoptosis.
    Chemico-biological interactions, 2019, Jan-25, Volume: 298

    Topics: Antineoplastic Agents; Apoptosis; Caspase 8; Cathepsin D; Cell Line, Tumor; Cell Survival; Chalcone; Humans; Leukemia; Membrane Potential, Mitochondrial; Pepstatins; Reactive Oxygen Species

2019
Antifungal dimeric chalcone derivative kamalachalcone E from Mallotus philippinensis.
    Natural product research, 2014, Volume: 28, Issue:4

    Topics: Antifungal Agents; Aspergillus fumigatus; Chalcone; Chalcones; Cryptococcus neoformans; Drug Screening Assays, Antitumor; Euphorbiaceae; Fruit; Fungi; Humans; India; Inhibitory Concentration 50; Leukemia; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Extracts; Yeasts

2014
3'-Geranyl-mono-substituted chalcone Xanthoangelovl induces apoptosis in human leukemia K562 cells via activation of mitochondrial pathway.
    Chemico-biological interactions, 2017, Jan-05, Volume: 261

    Topics: Apoptosis; Caspase 3; Cell Shape; Chalcone; Humans; K562 Cells; Leukemia; Membrane Potential, Mitochondrial; Mitochondria; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Necrosis Factor-alpha

2017
Naphthylchalcones induce apoptosis and caspase activation in a leukemia cell line: The relationship between mitochondrial damage, oxidative stress, and cell death.
    Bioorganic & medicinal chemistry, 2010, Nov-15, Volume: 18, Issue:22

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Chalcone; Chalcones; Humans; Leukemia; Mitochondria; Oxidative Stress; Reactive Oxygen Species

2010
Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:8

    Topics: Angelica; Apoptosis; Caspase 3; Caspases; Chalcone; Enzyme Activation; Humans; Leukemia; Neuroblastoma; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

2005
Synthesis, dimerization, and biological activity of hexaoxygenated chalcones related to calythropsin and combretastatins.
    Natural product letters, 2002, Volume: 16, Issue:3

    Topics: Animals; Brain; Chalcone; Drug Screening Assays, Antitumor; Inhibitory Concentration 50; Leukemia; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Photochemistry; Spectrophotometry, Infrared; Structure-Activity Relationship; Swine; Tubulin; Tumor Cells, Cultured

2002
New-type inducers of differentiation of HL-60 leukemia cells suppress c-myc expression.
    Chemical & pharmaceutical bulletin, 1987, Volume: 35, Issue:8

    Topics: Cell Differentiation; Cell Line; Chalcone; Chalcones; Humans; Leukemia; Oncogenes; Propiophenones; Proto-Oncogenes

1987