Page last updated: 2024-08-18

chalcone and Invasiveness, Neoplasm

chalcone has been researched along with Invasiveness, Neoplasm in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's13 (81.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Bahety, P; Boon, CP; Ee, PL; Lee, CY; Leow, PC; Tan, KL; Yang, T1
Bracke, ME; De Ryck, T; Roman, BI; Stevens, CV; Verhasselt, S1
Bracke, ME; De Ryck, T; Katritzky, AR; Patronov, A; Roman, BI; Slavov, SH; Stevens, CV; Vanhoecke, BW1
Lv, C; Su, D1
Chen, X; Gao, Y; Wang, Y; Zhang, L1
Chew, EH; Chui, WK; Gan, FF; Hadadi, E; Karuppasamy, M; Ng, HL; Ong, SM; Seah, W; Wong, SC; Yeap, WH; Zhang, R1
Bai, X; Dong, N; Li, H; Li, X; Liu, X; Wang, L; Yang, B; Zhang, S; Zhang, Y; Zhao, T1
Batko, B; Du, X; Geller, DS; Gill, J; Gorlick, R; Hoang, BH; Koirala, P; Liu, Y; O'Donnell, EF; Piperdi, S; Ren, T; Roth, M; Sato, K; Wang, J; Yang, R; Zaphiros, N; Zhang, J; Zhang, W; Zhang, Y; Zheng, D; Zi, X; Zvi, YS1
Jin, H; Kim, HS; Lee, SH; Seo, GS1
Lin, SH; Shih, YW1
Liu, M; Liu, Y; Qi, Z; Yang, G; Zhang, M1
Abdullah, MP; Abu, N; Akhtar, MN; Alitheen, NB; Ho, WY; Lim, KL; Omar, AR; Sulaiman, MR; Yeap, SK; Zulfadli, AJ1
Abdullah, MP; Abu, N; Akhtar, MN; Alitheen, NB; Kee, BB; Lim, KL; Mohamed, NE; Omar, AR; Yeap, SK; Zulfadli, AJ1
Cao, Q; Chen, GL; Fang, WH; Jiang, XR; Li, HH; Li, M; Li, Y; Liu, X; Ping, GF; Wang, LH; Wang, S; Wu, CF; Yang, JY1
Lee, JW; Lee, SA; Park, KH1
Bracke, ME; Jain, SC; Kumar, V; Mukherjee, S; Olsen, CE; Parmar, VS; Prasad, AK; Raj, HG1

Reviews

1 review(s) available for chalcone and Invasiveness, Neoplasm

ArticleYear
Modulation of signaling between TM4SF5 and integrins in tumor microenvironment.
    Frontiers in bioscience (Landmark edition), 2011, 01-01, Volume: 16, Issue:5

    Topics: Actins; Cell Movement; Cell Proliferation; Chalcone; Epithelial-Mesenchymal Transition; Integrins; Membrane Proteins; Neoplasm Invasiveness; Neovascularization, Pathologic; Sulfonamides; Tumor Microenvironment

2011

Other Studies

15 other study(ies) available for chalcone and Invasiveness, Neoplasm

ArticleYear
Functionalized curcumin analogs as potent modulators of the Wnt/β-catenin signaling pathway.
    European journal of medicinal chemistry, 2014, Volume: 71

    Topics: Antineoplastic Agents; beta Catenin; Bone Neoplasms; Cell Line, Tumor; Curcumin; HEK293 Cells; Humans; Neoplasm Invasiveness; Osteosarcoma; Wnt Signaling Pathway

2014
Further studies on anti-invasive chemotypes: An excursion from chalcones to curcuminoids.
    Bioorganic & medicinal chemistry letters, 2015, Mar-01, Volume: 25, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chalcones; Chickens; Curcumin; Halogenation; Heart; Humans; Neoplasm Invasiveness; Neoplasms; Structure-Activity Relationship

2015
4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent. From discovery to initial validation in an in vivo metastasis model.
    European journal of medicinal chemistry, 2015, Aug-28, Volume: 101

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Products; Cell Line, Tumor; Cell Movement; Cell Survival; Chalcones; Chick Embryo; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Female; Humans; Mice; Mice, Nude; Molecular Structure; Myocardium; Neoplasm Invasiveness; Neoplasm Metastasis; Quantitative Structure-Activity Relationship

2015
Hydroxysafflor yellow A inhibits the proliferation, migration, and invasion of colorectal cancer cells through the PPARγ/PTEN/Akt signaling pathway.
    Bioengineered, 2021, Volume: 12, Issue:2

    Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chalcone; Colorectal Neoplasms; Down-Regulation; Humans; Neoplasm Invasiveness; PPAR gamma; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinones; Signal Transduction

2021
Hydroxysafflor Yellow A of Carthamus Tinctorius L., Represses the Malignant Development of Esophageal Cancer Cells via Regulating NF-κB Signaling Pathway.
    Cell biochemistry and biophysics, 2020, Volume: 78, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Carcinogenesis; Carthamus tinctorius; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chalcone; Drug Discovery; Esophageal Neoplasms; Humans; Intercellular Adhesion Molecule-1; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-kappa B; Quinones; Signal Transduction; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2020
Novel dual-targeting anti-proliferative dihydrotriazine-chalcone derivatives display suppression of cancer cell invasion and inflammation by inhibiting the NF-κB signaling pathway.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 116, Issue:Pt B

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Cyclooxygenase 2; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Inflammation Mediators; Lipopolysaccharides; Matrix Metalloproteinase 9; Mice; Monocytes; Neoplasm Invasiveness; NF-kappa B; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Signal Transduction; Tetradecanoylphorbol Acetate; Triazines

2018
Apoptosis-inducing effects and growth inhibitory of a novel chalcone, in human hepatic cancer cells and lung cancer cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 105

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chalcone; Humans; Liver Neoplasms; Lung Neoplasms; Mice; Molecular Docking Simulation; Neoplasm Invasiveness; Up-Regulation; Xenograft Model Antitumor Assays

2018
Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma.
    Scientific reports, 2018, 09-24, Volume: 8, Issue:1

    Topics: Administration, Oral; Animals; Cell Line, Tumor; Cell Proliferation; Chalcone; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Osteosarcoma; Prognosis; S-Phase Kinase-Associated Proteins

2018
A new chalcone derivative, 3-phenyl-1-(2,4,6-tris(methoxymethoxy)phenyl)prop-2-yn-1-one), inhibits phorbol ester-induced metastatic activity of colorectal cancer cells through upregulation of heme oxygenase-1.
    European journal of pharmacology, 2018, Dec-15, Volume: 841

    Topics: Cell Movement; Cell Proliferation; Chalcone; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; Heme Oxygenase-1; HT29 Cells; Humans; Matrix Metalloproteinase 7; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Phorbol Esters; Up-Regulation

2018
Antitumor effects of the flavone chalcone: inhibition of invasion and migration through the FAK/JNK signaling pathway in human gastric adenocarcinoma AGS cells.
    Molecular and cellular biochemistry, 2014, Volume: 391, Issue:1-2

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Adhesion; Cell Death; Cell Line, Tumor; Cell Movement; Cell Survival; Cell-Matrix Junctions; Chalcone; DNA; Flavones; Focal Adhesion Protein-Tyrosine Kinases; Humans; I-kappa B Proteins; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Proteolysis; Stomach Neoplasms; Urokinase-Type Plasminogen Activator

2014
Tetramethoxychalcone, a chalcone derivative, suppresses proliferation, blocks cell cycle progression, and induces apoptosis of human ovarian cancer cells.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chalcone; Chalcones; Female; G1 Phase Cell Cycle Checkpoints; Humans; Inhibitory Concentration 50; Neoplasm Invasiveness; Ovarian Neoplasms; Polymerization; Resting Phase, Cell Cycle; Signal Transduction; Solubility; Tubulin; Tumor Stem Cell Assay

2014
Flavokawain A induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chalcone; Female; G2 Phase; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Male; MCF-7 Cells; Membrane Potential, Mitochondrial; Mitosis; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction

2014
In Vivo Anti-Tumor Effects of Flavokawain A in 4T1 Breast Cancer Cell-Challenged Mice.
    Anti-cancer agents in medicinal chemistry, 2015, Volume: 15, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chalcone; Female; Immunologic Factors; Inflammation; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Nitric Oxide; T-Lymphocytes; Tumor Burden

2015
SL4, a chalcone-based compound, induces apoptosis in human cancer cells by activation of the ROS/MAPK signalling pathway.
    Cell proliferation, 2015, Volume: 48, Issue:6

    Topics: Animals; Anthracenes; Apoptosis; bcl-X Protein; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Enzyme Activation; Female; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1; Imidazoles; Inhibitor of Apoptosis Proteins; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Pyridines; Reactive Oxygen Species; Survivin; X-Linked Inhibitor of Apoptosis Protein

2015
Synthetic and biological activity evaluation studies on novel 1,3-diarylpropenones.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:2

    Topics: Acetophenones; Animals; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Chalcone; Chick Embryo; Coculture Techniques; Combinatorial Chemistry Techniques; Drug Evaluation, Preclinical; Female; Humans; Lipid Peroxidation; Microsomes, Liver; Myocardium; Neoplasm Invasiveness; Rats; Structure-Activity Relationship; Tumor Cells, Cultured

2001