Page last updated: 2024-08-18

chalcone and Edema

chalcone has been researched along with Edema in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's2 (10.00)18.2507
2000's7 (35.00)29.6817
2010's7 (35.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Guo, Z; Li, D; Li, J; Liu, X; Wang, L; Wu, L; Xu, Y; Yang, H1
Cechinel Filho, V; Da Silva, GF; De Campos Buzzi, F; Escalante-Erosa, F; Klein, LC; Peña Rodriguez, LM; Quintão, NLM; Santin, JR; Sosa, KG; Yam-Puc, A1
Balaini, A; Bali, A; Chaudhari, BB1
Baracat, MM; Bottura, C; Bussmann, AJC; Casagrande, R; Caviglione, CV; Fattori, V; Fonseca, MJV; Georgetti, SR; Martinez, RM; Pinho-Ribeiro, FA; Steffen, VS; Verri, WA; Vignoli, JA1
Chen, JJ; Geng, CA; Hou, B; Huang, XY; Ma, YB; Peng, H; Yan, DX; Yang, TH; Zhang, XM1
Aguilar-Mariscal, H; Gómez-Rivera, A; Lobato-García, CE; Roa-de la Fuente, LF; Romero-Ceronio, N1
Azimzadeh, BS; Foroumadi, A; Heidari, MR; Noroozi, H; Samzadeh-Kermani, A1
Bhatia, G; Khanna, AK; Kumar, M; Modukuri, RK; Rai, S; Sashidhara, KV; Shukla, R; Sonkar, R1
Abdel-Aziz, M; Abuo-Rahma, Gel-D; Farag, HH; Mourad, MA1
Cao, D; Chen, J; Chen, L; Deng, C; Li, X; Liang, X; Ma, L; Peng, A; Peng, F; Qiu, J; Ran, Y; Wang, G; Wei, Y; Xiang, M; Xie, C; Yang, Z; Ye, H1
Charris, JE; Domínguez, JN; Ferrándiz, ML; Lobo, G; Payá, M; Rojas, J1
Bandeira, MA; Matos, FJ; Viana, GS1
Alcaraz, MJ; Charris, J; De León, EJ; Dominguez, JN; Terencio, MC1
Izumi, A; Matsumoto, H; Miki, T; Nihro, Y; Satoh, T; Sogawa, S; Ueda, H1
Inoue, H; Iwata, S; Nagata, N; Nishino, H; Nishino, T; Satomi, Y; Shibata, S1
Alcaraz, MJ; Charris, JE; Dominguez, JN; Ferrándiz, ML; Guillén, I; Herencia, F; Lobo, GM; Ubeda, A1
Hammock, BD; Lakritz, J; Plopper, CG; Storms, DH; Zheng, J1
Claeson, P; Pongprayoon, U; Reutrakul, V; Santisuk, T; Sematong, T; Taylor, WC; Tuchinda, P1
Neumann-Mangoldt, P1
Fujimoto, Y; Inoue, H; Koshihara, Y1

Trials

1 trial(s) available for chalcone and Edema

ArticleYear
[Experiences in the use of Essaven capsules in the treatment of venous leg diseases. Results of a double-blind study].
    Fortschritte der Medizin, 1979, Dec-01, Volume: 97, Issue:45

    Topics: Adult; Chalcone; Clinical Trials as Topic; Diuresis; Double-Blind Method; Drug Combinations; Drug Evaluation; Edema; Escin; Flavonoids; Hesperidin; Humans; Pain; Propiophenones; Saponins; Skin Manifestations; Thromboembolism

1979

Other Studies

19 other study(ies) available for chalcone and Edema

ArticleYear
Design, synthesis, biological evaluation, and molecular docking of chalcone derivatives as anti-inflammatory agents.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Chalcone; Cyclooxygenase 2; Drug Design; Edema; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Molecular Docking Simulation; Protein Structure, Tertiary; RAW 264.7 Cells; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; Xylenes

2017
Anti-inflammatory and anti-hypersensitive effects of the chalcone isocordoin and its semisynthetic derivatives in mice.
    Behavioural pharmacology, 2020, Volume: 31, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Catechols; Chalcone; Chalcones; Edema; Fabaceae; Female; Hyperalgesia; Male; Mice; Plant Extracts

2020
Design and Synthesis of Novel Anti-inflammatory/Anti-ulcer Hybrid Molecules with Antioxidant Activity.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2021, Volume: 17, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Chalcone; Drug Design; Drug Evaluation, Preclinical; Edema; Female; Isoxazoles; Male; Molecular Structure; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship

2021
trans-Chalcone, a flavonoid precursor, inhibits UV-induced skin inflammation and oxidative stress in mice by targeting NADPH oxidase and cytokine production.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2017, Jul-01, Volume: 16, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chalcone; Cytokines; Dose-Response Relationship, Drug; Edema; Enzyme-Linked Immunosorbent Assay; Inflammation; Male; Mice; Mice, Hairless; Molecular Structure; NADPH Oxidases; Oxidative Stress; Skin; Structure-Activity Relationship; Ultraviolet Rays

2017
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis.
    Phytochemistry, 2019, Volume: 164

    Topics: Anacardiaceae; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Chalcone; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Flavanones; Hyperuricemia; Inflammation; Male; Mice; Mice, Inbred Strains; Molecular Structure; Oxonic Acid; Structure-Activity Relationship; Uric Acid; Xanthine Oxidase

2019
Synthesis and anti-inflammatory activity of three nitro chalcones.
    Bioorganic & medicinal chemistry letters, 2013, Oct-15, Volume: 23, Issue:20

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Area Under Curve; Chalcone; Disease Models, Animal; Edema; Rats; ROC Curve

2013
Study of the anti-inflammatory and analgesic effects of novel rigid benzofuran-3, 4-dihydroxy chalcone by formalin, hot-plate and carrageenan tests in mice.
    Pakistan journal of pharmaceutical sciences, 2009, Volume: 22, Issue:4

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Benzofurans; Carrageenan; Chalcone; Dose-Response Relationship, Drug; Edema; Foot; Formaldehyde; Hot Temperature; Male; Mice; Pain Measurement

2009
Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids.
    Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chalcone; Coumarins; Edema; Microsomes; Rats

2011
Synthesis, anti-inflammatory activity and ulcerogenic liability of novel nitric oxide donating/chalcone hybrids.
    Bioorganic & medicinal chemistry, 2012, Jan-01, Volume: 20, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chalcone; Edema; Gastrointestinal Tract; Indomethacin; Nitric Oxide; Nitric Oxide Donors; Rats

2012
Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents.
    European journal of medicinal chemistry, 2012, Volume: 54

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Benzopyrans; Carrageenan; Catalytic Domain; Cell Line; Chalcone; Chalcones; Chemistry Techniques, Synthetic; Drug Design; Edema; Male; Mice; Molecular Docking Simulation; Nitric Oxide Synthase Type II

2012
Synthesis and inhibitory activity of dimethylamino-chalcone derivatives on the induction of nitric oxide synthase.
    European journal of medicinal chemistry, 2002, Volume: 37, Issue:8

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Cell Line; Chalcone; Dimethylamines; Dinoprostone; Drug Evaluation, Preclinical; Edema; Enzyme Induction; Macrophages; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Structure-Activity Relationship

2002
Analgesic and antiinflammatory effects of chalcones isolated from Myracrodruon urundeuva allemão.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2003, Volume: 10, Issue:2-3

    Topics: Abdominal Muscles; Anacardiaceae; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brazil; Carrageenan; Chalcone; Chalcones; Edema; Female; Hindlimb; Hot Temperature; Male; Mice; Pain Measurement; Pain Threshold; Phytotherapy; Plant Extracts; Sensory Thresholds

2003
1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one, a chalcone derivative with analgesic, anti-inflammatory and immunomodulatory properties.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2003, Volume: 52, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Blotting, Western; Cell Division; Chalcone; Chalcones; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Edema; Electrophoretic Mobility Shift Assay; Humans; Hypersensitivity, Delayed; In Vitro Techniques; Indicators and Reagents; Isoenzymes; Leukocyte Elastase; Leukotriene B4; Luminescent Measurements; Lymphocyte Activation; Macrophage Activation; Membrane Proteins; Mice; Neutrophil Activation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pain; Pain Measurement; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Quinolines

2003
3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors.
    Journal of medicinal chemistry, 1993, Nov-26, Volume: 36, Issue:24

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cell Line; Chalcone; Chalcones; Cyclooxygenase Inhibitors; Edema; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred ICR; Molecular Structure; Sheep; Structure-Activity Relationship

1993
Antitumorigenic activities of chalcones (II). Photo-isomerization of chalcones and the correlation with their biological activities.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:12

    Topics: Animals; Anticarcinogenic Agents; Cell Division; Chalcone; Chromatography, High Pressure Liquid; Edema; Female; HeLa Cells; Humans; Isomerism; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Ornithine Decarboxylase; Phospholipids; Photochemistry; Receptors, Estrogen; Skin

1997
4-dimethylamino-3',4'-dimethoxychalcone downregulates iNOS expression and exerts anti-inflammatory effects.
    Free radical biology & medicine, 2001, Jan-01, Volume: 30, Issue:1

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Anti-Inflammatory Agents; Carrageenan; Chalcone; Chalcones; Edema; Enzyme Inhibitors; Female; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Inflammation; Luminescent Measurements; Macrophages, Peritoneal; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Respiratory Burst; Superoxides; Zymosan

2001
Leukotoxin-diol: a putative toxic mediator involved in acute respiratory distress syndrome.
    American journal of respiratory cell and molecular biology, 2001, Volume: 25, Issue:4

    Topics: Animals; Chalcone; Chalcones; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Epoxide Hydrolases; Exotoxins; Lung; Male; Mice; Respiratory Distress Syndrome; Stearic Acids

2001
Anti-inflammatory cyclohexenyl chalcone derivatives in Boesenbergia pandurata.
    Phytochemistry, 2002, Volume: 59, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Chalcone; Cyclohexanes; Ear; Edema; Rats; Tetradecanoylphorbol Acetate; Zingiberaceae

2002
A new 5-lipoxygenase selective inhibitor derived from Artocarpus communis strongly inhibits arachidonic acid-induced ear edema.
    Biochemical pharmacology, 1988, Jun-01, Volume: 37, Issue:11

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Chalcone; Chalcones; Dose-Response Relationship, Drug; Edema; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred ICR; Plant Extracts; Propiophenones; SRS-A; Terpenes

1988