Page last updated: 2024-08-18

chalcone and Breast Neoplasms

chalcone has been researched along with Breast Neoplasms in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (3.03)	18.2507
2000's	6 (18.18)	29.6817
2010's	21 (63.64)	24.3611
2020's	5 (15.15)	2.80

Authors

Authors	Studies
Babu, B; Nyokong, T; Openda, YI	1
Bradshaw, B; Bustos, L; Castro-Alvarez, A; Cuellar, M; Echiburú-Chau, C; Mellado, M; Parra, C; Simirgiotis, MJ	1
Gines, BR; Russell, AE	1
Chen, G; Chen, J; Gao, X; Jin, X; Lai, W; Ye, L	1
Jana, K; Manna, T; Misra, AK; Pal, K	1
Abuo-Rahma, GEA; Alaaeldin, R; Fathy, M; Zhao, QL	1
Chen, L; Hoang, BH; Jandial, DD; Ke, Y; Krill, LS; Wu, C; Xie, J; Zi, X	1
Chen, B; Chen, J; Gao, F; Huang, X; Peng, F; Shen, J; Tang, H; Xie, X; You, J	1
Androutsopoulos, VP; Spandidos, DA	1
Ankrett, DN; Arroo, RRJ; Beresford, KJM; Bhambra, AS; Butler, PC; Ijaz, T; Lodhi, S; Potter, GA; Ruparelia, KC; Tan, HL; Wilsher, NE; Zeka, K	1
Chew, EH; Chui, WK; Gan, FF; Hadadi, E; Karuppasamy, M; Ng, HL; Ong, SM; Seah, W; Wong, SC; Yeap, WH; Zhang, R	1
Chittiboyina, A; Liu, Y; Pandey, PR; Sharma, S; Tyagi, A; Watabe, K; Wu, K; Wu, SY; Xing, F	1
Chen, X; Chen, Y; Dong, K; Li, D; Lin, H; Liu, X; Pan, Z; Qu, C; Xu, W; Zheng, Q; Zhu, W	1
Algul, O; Ates, B; Balcioglu, S; Burmaoglu, S; Essiz, S; Gencel, M; Noma, SAA; Ozcan, S	1
Abdullah, MP; Abu, N; Akhtar, MN; Alitheen, NB; Ho, WY; Lim, KL; Omar, AR; Sulaiman, MR; Yeap, SK; Zulfadli, AJ	1
Chen, YL; Cheng, CM; Hsu, CY; Tseng, CH; Tzeng, CC; Yang, CN	1
Bargsten, K; Benkheil, M; Bueno, O; Camarasa, MJ; Canela, MD; Díaz, JF; Jimeno, ML; Liekens, S; Noppen, S; Pérez-Pérez, MJ; Priego, EM; Prota, AE; Ribatti, D; Sáez-Calvo, G; Steinmetz, MO; Velázquez, S	1
Fu, H; Li, Y; Shou, Q; Tang, X; Tu, J; Wang, J; Wu, R; Zhang, L; Zhou, W	1
Baek, SJ; Barbosa, FR; Beleboni, RO; Bitencourt, TA; Bortolotto, LF; Fachin, AL; Marins, M; Silva, G	1
Begnini, KR; Carapina, C; Collares, T; de Pereira, CM; Fogaça, TB; Martins, RM; Ritter, M; Seixas, FK	1
Dong, J; Liu, M; Miao, J; Qian, X; Qian, Z; Yin, H	1
Lee, H; Solomon, VR	1
Gong, HB; Liu, JJ; Lu, X; Sun, J; Yang, XH; Zhang, H; Zhao, TT; Zhu, HL	1
Amerik, AY; Issaenko, OA	1
Chen, TC; Chen, YL; Cheng, CM; Hsu, CY; Lu, YJ; Tseng, CH; Tso, HC; Tzeng, CC	1
Burow, ME; Carriere, P; Gray, M; Johnson, KP; McLachlan, JA; Ochieng, J; Rhodes, LV; Stoute, D; Tilghman, SL; Yearby, LA	1
Amdò, S; Gabriele, S; Loizzo, M; Maggiolini, M; Menichini, F; Rago, V; Statti, G; Vivacqua, A	1
Chorn, G; Samoszuk, M; Tan, J	1
Chan, FL; Chen, S; Leung, LK; Wang, Y	1
Hsu, YL; Kuo, PL; Lin, CC; Tzeng, WS	1
Belluti, F; Bombardelli, E; De Vincenzo, R; Distefano, M; Ferlini, C; Gaggini, C; Mancuso, S; Morazzoni, P; Ranelletti, FO; Riva, A; Scambia, G; Valenti, P	1
Bracke, ME; Jain, SC; Kumar, V; Mukherjee, S; Olsen, CE; Parmar, VS; Prasad, AK; Raj, HG	1
Alejandro, M; Clark, JH; Gregory, RR; Kittrell, FS; Markaverich, BM; Medina, D; Varma, M; Varma, RS	1

Other Studies

33 other study(ies) available for chalcone and Breast Neoplasms

Article	Year
Novel cationic-chalcone phthalocyanines for photodynamic therapy eradication of S. aureus and E. coli bacterial biofilms and MCF-7 breast cancer. Photodiagnosis and photodynamic therapy, 2022, Volume: 38 Topics: Anti-Bacterial Agents; Biofilms; Breast Neoplasms; Chalcone; Chalcones; Escherichia coli; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indoles; MCF-7 Cells; Methicillin-Resistant Staphylococcus aureus; Photochemotherapy; Photosensitizing Agents; Plankton; Staphylococcus aureus	2022
Cytotoxic Effects on Breast Cancer Cell Lines of Chalcones Derived from a Natural Precursor and Their Molecular Docking Analysis. Molecules (Basel, Switzerland), 2022, Jul-08, Volume: 27, Issue:14 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Chalcone; Chalcones; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship	2022
Chalcones: Potential Chemotherapeutic Compounds and Educational Tools for Closing the Loop in STEM. Accounts of chemical research, 2023, 06-06, Volume: 56, Issue:11 Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Chalcone; Chalcones; Drug Screening Assays, Antitumor; Female; Humans; Structure-Activity Relationship	2023
Design and Synthesis of Novel Chalcone Derivatives: Anti-Breast Cancer Activity Evaluation and Docking Study. International journal of molecular sciences, 2023, Oct-25, Volume: 24, Issue:21 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship	2023
Anti-cancer potential of novel glycosylated 1,4-substituted triazolylchalcone derivatives. Bioorganic & medicinal chemistry letters, 2019, 10-01, Volume: 29, Issue:19 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Chalcone; Click Chemistry; Cycloaddition Reaction; Drug Screening Assays, Antitumor; Female; Glycosylation; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles	2019
Modulation of Apoptosis and Epithelial-Mesenchymal Transition E-cadherin/TGF-β/Snail/TWIST Pathways by a New Ciprofloxacin Chalcone in Breast Cancer Cells. Anticancer research, 2021, Volume: 41, Issue:5 Topics: Apoptosis; Breast Neoplasms; Cadherins; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Chalcone; Ciprofloxacin; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Molecular Structure; Proteins; Signal Transduction; Snail Family Transcription Factors; Transforming Growth Factor beta; Twist-Related Protein 1	2021
Induction of G2M Arrest by Flavokawain A, a Kava Chalcone, Increases the Responsiveness of HER2-Overexpressing Breast Cancer Cells to Herceptin. Molecules (Basel, Switzerland), 2017, Mar-14, Volume: 22, Issue:3 Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chalcone; Drug Screening Assays, Antitumor; Drug Synergism; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Receptor, ErbB-2; Trastuzumab	2017
Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer. Current cancer drug targets, 2018, Volume: 18, Issue:4 Topics: Animals; beta Catenin; Breast Neoplasms; Carcinogenesis; Chalcone; Dose-Response Relationship, Drug; Drug Delivery Systems; Endoplasmic Reticulum Chaperone BiP; Glucosides; Heat-Shock Proteins; Humans; MCF-7 Cells; Mice; Mice, Nude; Xenograft Model Antitumor Assays	2018
Anticancer pyridines induce G2/M arrest and apoptosis via p53 and JNK upregulation in liver and breast cancer cells. Oncology reports, 2018, Volume: 39, Issue:2 Topics: Breast Neoplasms; Cell Proliferation; Cell Survival; Chalcone; Drug Screening Assays, Antitumor; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Male; MAP Kinase Kinase 4; MCF-7 Cells; Pyridines; Tumor Suppressor Protein p53; Up-Regulation	2018
The Synthesis of Chalcones as Anticancer Prodrugs and their Bioactivation in CYP1 Expressing Breast Cancer Cells. Medicinal chemistry (Shariqah (United Arab Emirates)), 2018, Volume: 14, Issue:4 Topics: Antineoplastic Agents; Benzoflavones; Breast Neoplasms; Cell Line, Tumor; Chalcone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Flavones; Humans; Molecular Structure; Prodrugs	2018
Novel dual-targeting anti-proliferative dihydrotriazine-chalcone derivatives display suppression of cancer cell invasion and inflammation by inhibiting the NF-κB signaling pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 116, Issue:Pt B Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Cyclooxygenase 2; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Inflammation Mediators; Lipopolysaccharides; Matrix Metalloproteinase 9; Mice; Monocytes; Neoplasm Invasiveness; NF-kappa B; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Signal Transduction; Tetradecanoylphorbol Acetate; Triazines	2018
ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness. Breast cancer research and treatment, 2019, Volume: 175, Issue:1 Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Proliferation; Chalcone; Connexin 26; Connexins; Disease Models, Animal; Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Inhibitor of Differentiation Protein 2; Mice; Neoplasm Staging; Neoplastic Stem Cells; Prognosis; Promoter Regions, Genetic	2019
Inhibitory Effect of Hydroxysafflor Yellow B on the Proliferation of Human Breast Cancer MCF-7 Cells. Recent patents on anti-cancer drug discovery, 2019, Volume: 14, Issue:2 Topics: Adenocarcinoma; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Proliferation; Chalcone; Female; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Pigments, Biological; Quinones; Signal Transduction	2019
Synthesis, biological evaluation and molecular docking studies of bis-chalcone derivatives as xanthine oxidase inhibitors and anticancer agents. Bioorganic chemistry, 2019, Volume: 91 Topics: Antineoplastic Agents; Breast Neoplasms; Catalytic Domain; Cell Proliferation; Cell Survival; Chalcone; Enzyme Inhibitors; Female; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured; Xanthine Oxidase	2019
Flavokawain A induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro. PloS one, 2014, Volume: 9, Issue:10 Topics: Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chalcone; Female; G2 Phase; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Male; MCF-7 Cells; Membrane Potential, Mitochondrial; Mitosis; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction	2014
Discovery of 3-phenylquinolinylchalcone derivatives as potent and selective anticancer agents against breast cancers. European journal of medicinal chemistry, 2015, Jun-05, Volume: 97 Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Proliferation; Chalcone; Cyclin B1; Cyclin-Dependent Kinases; Drug Discovery; Female; Fluorescent Antibody Technique; G2 Phase Cell Cycle Checkpoints; Humans; Immunoblotting; Models, Molecular; Molecular Structure; Proto-Oncogene Proteins c-bcl-2; Quinolines; Quinolones; Tumor Cells, Cultured	2015
Antivascular and antitumor properties of the tubulin-binding chalcone TUB091. Oncotarget, 2017, Feb-28, Volume: 8, Issue:9 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Benzodioxoles; Binding Sites; Breast Neoplasms; Cell Movement; Cell Proliferation; Cells, Cultured; Chalcone; Chalcones; Crystallography, X-Ray; Dipeptides; Endothelium, Vascular; Female; Humans; Melanoma, Experimental; Mice; Mice, SCID; Neovascularization, Pathologic; Prodrugs; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Xenograft Model Antitumor Assays	2017
Safflower Yellow Prevents Pulmonary Metastasis of Breast Cancer by Inhibiting Tumor Cell Invadopodia. The American journal of Chinese medicine, 2016, Volume: 44, Issue:7 Topics: Animals; Breast Neoplasms; Carthamus tinctorius; Chalcone; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermal Growth Factor; Female; Humans; Lung Neoplasms; Matrix Metalloproteinase 9; MCF-7 Cells; Mice; Mice, Inbred BALB C; Phytotherapy; Podosomes; Proto-Oncogene Proteins pp60(c-src)	2016
Cytotoxicity of trans-chalcone and licochalcone A against breast cancer cells is due to apoptosis induction and cell cycle arrest. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 85 Topics: 3T3 Cells; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Chalcone; Chalcones; Dose-Response Relationship, Drug; Female; Humans; L-Lactate Dehydrogenase; MCF-7 Cells; Mice; Molecular Structure; Promoter Regions, Genetic	2017
Apoptotic effect of chalcone derivatives of 2-acetylthiophene in human breast cancer cells. Pharmacological reports : PR, 2017, Volume: 69, Issue:1 Topics: Apoptosis; Breast Neoplasms; Cell Survival; Chalcone; Dose-Response Relationship, Drug; Female; Growth Inhibitors; Humans; MCF-7 Cells; Thiophenes	2017
Xanthohumol, a Prenylated Chalcone from Hops, Inhibits the Viability and Stemness of Doxorubicin-Resistant MCF-7/ADR Cells. Molecules (Basel, Switzerland), 2016, Dec-28, Volume: 22, Issue:1 Topics: Antibiotics, Antineoplastic; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle Checkpoints; Cell Movement; Cell Survival; Chalcone; Doxorubicin; Drug Resistance, Neoplasm; Flavonoids; Humans; Humulus; MCF-7 Cells; Neoplastic Stem Cells; Propiophenones; Spheroids, Cellular; Tumor Cells, Cultured	2016
Anti-breast cancer activity of heteroaryl chalcone derivatives. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2012, Volume: 66, Issue:3 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Drug Screening Assays, Antitumor; Female; Humans; Structure-Activity Relationship	2012
Design, synthesis and biological evaluation of novel chalcone derivatives as antitubulin agents. Bioorganic & medicinal chemistry, 2012, May-15, Volume: 20, Issue:10 Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Drug Design; Female; Humans; Inhibitory Concentration 50; Models, Molecular; Tubulin Modulators	2012
Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes. Cell cycle (Georgetown, Tex.), 2012, 05-01, Volume: 11, Issue:9 Topics: Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Boronic Acids; Bortezomib; Breast Neoplasms; Catalytic Domain; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Chalcone; Cyclin D1; Cysteine; Dose-Response Relationship, Drug; Endopeptidases; Female; HeLa Cells; Humans; Ovarian Neoplasms; Phenotype; Piperidones; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Tumor Suppressor Protein p53; Ubiquitin Thiolesterase; Ubiquitins	2012
Synthesis and antiproliferative evaluation of 3-phenylquinolinylchalcone derivatives against non-small cell lung cancers and breast cancers. European journal of medicinal chemistry, 2013, Volume: 59 Topics: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chalcone; Drug Screening Assays, Antitumor; Female; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Quinolines	2013
In vitro and in vivo evaluation of novel anticancer agents in triple negative breast cancer models. Journal of health care for the poor and underserved, 2013, Volume: 24, Issue:1 Suppl Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Female; Humans; Mice; Mice, SCID; Tumor Burden; Xenograft Model Antitumor Assays	2013
Estrogenic and antiproliferative activities of isoliquiritigenin in MCF7 breast cancer cells. The Journal of steroid biochemistry and molecular biology, 2002, Volume: 82, Issue:4-5 Topics: Breast Neoplasms; Cell Division; Chalcone; Chalcones; Down-Regulation; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; HeLa Cells; Humans; In Vitro Techniques; Plant Extracts; Proteins; Receptors, Estrogen; RNA, Neoplasm; Transfection; Trefoil Factor-1; Tumor Suppressor Proteins; Up-Regulation	2002
The chalcone butein from Rhus verniciflua Stokes inhibits clonogenic growth of human breast cancer cells co-cultured with fibroblasts. BMC complementary and alternative medicine, 2005, Mar-09, Volume: 5 Topics: Aged; Breast Neoplasms; Cell Proliferation; Chalcone; Chalcones; Clone Cells; Coculture Techniques; Dose-Response Relationship, Drug; Female; Fibroblasts; Growth Inhibitors; Humans; Phytotherapy; Plant Stems; Rhus; Tumor Cells, Cultured	2005
The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase. Life sciences, 2005, May-20, Volume: 77, Issue:1 Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Female; Flavonoids; Humans; Phenols; Polyphenols; Testosterone	2005
Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2006, Volume: 44, Issue:5 Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Breast Neoplasms; Caspase 9; Caspases; Cell Cycle; Cell Division; Chalcone; Cyclin A; Cyclin B; Cyclin B1; Dose-Response Relationship, Drug; Fas Ligand Protein; G2 Phase; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Membrane Glycoproteins; Mitosis; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Tumor Necrosis Factors	2006
In vitro evaluation of newly developed chalcone analogues in human cancer cells. Cancer chemotherapy and pharmacology, 2000, Volume: 46, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Cell Cycle; Cell Survival; Chalcone; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fabaceae; Genes, MDR; Humans; Jurkat Cells; Plants, Medicinal; Reactive Oxygen Species; Rhodamine 123; Tumor Cells, Cultured	2000
Synthetic and biological activity evaluation studies on novel 1,3-diarylpropenones. Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:2 Topics: Acetophenones; Animals; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Chalcone; Chick Embryo; Coculture Techniques; Combinatorial Chemistry Techniques; Drug Evaluation, Preclinical; Female; Humans; Lipid Peroxidation; Microsomes, Liver; Myocardium; Neoplasm Invasiveness; Rats; Structure-Activity Relationship; Tumor Cells, Cultured	2001
Methyl p-hydroxyphenyllactate and nuclear type II binding sites in malignant cells: metabolic fate and mammary tumor growth. Cancer research, 1990, Mar-01, Volume: 50, Issue:5 Topics: Animals; Binding, Competitive; Breast Neoplasms; Cell Nucleus; Chalcone; Chalcones; Cytosol; Esterases; Female; Humans; Lactates; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Propiophenones; Receptors, Estradiol; Tumor Cells, Cultured	1990