chalcone has been researched along with Alloxan Diabetes in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 5 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Adelusi, T; Chowdhry, A; Du, L; Gu, X; Hao, M; Li, X; Lu, Q; Sun, Y; Xu, L; Yin, X; Zhou, X | 1 |
| Chen, JG; Lin, P; Peng, DY; Tang, DB; Tu, YG; Xiao, PJ; Yin, ZP; Yuan, E; Zeng, JC; Zhang, QF | 1 |
| Aiebchun, T; Chavasiri, W; Kaewin, S; Korkut, GG; Muanprasat, C; Patrakka, J; Poolsri, W; Rungrotmongkol, T; Sukanadi, IB; Sungkaworn, T | 1 |
| Chen, J; Chu, S; Deng, Y; Kou, X; Lee, M; Li, H; Li, Z; Liao, S; Liu, D; Liu, X; Xie, W; Zhao, H | 1 |
| Danduga, RCSR; Kola, PK; Konidala, SK; Kotra, V | 1 |
| Chang, C; Gao, JQ; Gao, SQ; Li, LJ; Niu, XQ; Zhang, Y | 1 |
| Chang, C; Gao, JQ; Gao, SQ; Li, JJ; Li, LJ; Li, Y; Niu, XQ; Zhang, DP | 1 |
| Chen, R; Fang, Q; Jin, Y; Khan, Z; Li, W; Liang, G; Liu, Z; Shan, X; Wang, Y; Yu, W; Zou, C | 1 |
| Li, L; Liu, B; Zhao, Y; Zhong, J | 1 |
| He, H; Li, L; Liu, Q; Shi, M; Wu, L; Yang, J; Zeng, X | 1 |
| Pratap, R; Satyanarayana, M; Srivastava, AK; Tiwari, P; Tripathi, BK | 1 |
| Ji, J; Jung, SH; Keum, SR; Lim, SS; Shin, KH | 1 |
| Aida, K; Onaya, T; Shindo, H; Tawata, M | 1 |
| Inoue, M; Noguchi, T; Onaya, T; Shindo, H; Tawata, M; Wakasugi, M | 1 |
| Aida, K; Chin, M; Mitsuhashi, H; Onaya, T; Sasaki, H; Shindo, H; Tawata, M; Yamaguchi, T | 1 |
15 other study(ies) available for chalcone and Alloxan Diabetes
| Article | Year |
|---|---|
Novel Chalcone BDD-39 Mitigated Diabetic Nephropathy through the Activation of Nrf2/ARE Signaling.
Topics: Animals; Biphenyl Compounds; Chalcone; Chalcones; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fibrosis; Mice; NF-E2-Related Factor 2; Oxidative Stress; RNA; Signal Transduction | 2022 |
Chalcone-1-Deoxynojirimycin Heterozygote Reduced the Blood Glucose Concentration and Alleviated the Adverse Symptoms and Intestinal Flora Disorder of Diabetes Mellitus Rats.
Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Chalcone; Chalcones; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gastrointestinal Microbiome; Heterozygote; Hypoglycemic Agents; Rats | 2022 |
A sulfonamide chalcone AMPK activator ameliorates hyperglycemia and diabetic nephropathy in db/db mice.
Topics: AMP-Activated Protein Kinases; Animals; Calcium; Chalcone; Chalcones; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Humans; Hyperglycemia; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Docking Simulation | 2023 |
Protective Effect of Hydroxysafflor Yellow A on Nephropathy by Attenuating Oxidative Stress and Inhibiting Apoptosis in Induced Type 2 Diabetes in Rat.
Topics: Animals; Apoptosis; Chalcone; Diabetes Mellitus, Experimental; Kidney Diseases; Male; Oxidative Stress; Quinones; Rats; Rats, Wistar | 2020 |
Coumarin-chalcone hybrids targeting insulin receptor: Design, synthesis, anti-diabetic activity, and molecular docking.
Topics: Administration, Oral; Animals; Antigens, CD; Chalcone; Coumarins; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Design; Female; Humans; Hypoglycemic Agents; Injections, Intraperitoneal; Male; Molecular Docking Simulation; Molecular Structure; Rats; Rats, Wistar; Receptor, Insulin; Streptozocin; Structure-Activity Relationship | 2020 |
Topical application of Hydroxysafflor Yellow A accelerates the wound healing in streptozotocin induced T1DM rats.
Topics: Administration, Topical; Animals; Chalcone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Human Umbilical Vein Endothelial Cells; Humans; Kinetics; Male; Nitric Oxide; Quinones; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Wound Healing | 2018 |
Co-delivery of deferoxamine and hydroxysafflor yellow A to accelerate diabetic wound healing via enhanced angiogenesis.
Topics: Administration, Topical; Animals; Chalcone; Deferoxamine; Diabetes Mellitus, Experimental; Drug Delivery Systems; Drug Therapy, Combination; Humans; Male; Neovascularization, Physiologic; Quinones; Rats, Sprague-Dawley; Siderophores; Wound Healing | 2018 |
Blockade of myeloid differentiation 2 attenuates diabetic nephropathy by reducing activation of the renin-angiotensin system in mouse kidneys.
Topics: Animals; Cells, Cultured; Chalcone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Kidney; Lymphocyte Antigen 96; Mice; Mice, Inbred C57BL; Mice, Knockout; Renin-Angiotensin System; RNA, Small Interfering; Streptozocin | 2019 |
[Effects of angelica keiskei chalcone on expression of glucose transporter proteins in liver and skeletal muscle cells of type 2 diabetic rats].
Topics: Angelica; Animals; Chalcone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Transporter Type 2; Glucose Transporter Type 4; Insulin Resistance; Liver; Male; Muscle, Skeletal; Rats; Rats, Wistar | 2013 |
Cardioprotective effects of hydroxysafflor yellow A on diabetic cardiac insufficiency attributed to up-regulation of the expression of intracellular calcium handling proteins of sarcoplasmic reticulum in rats.
Topics: Administration, Oral; Animals; Calcium Signaling; Calcium-Binding Proteins; Cardiomyopathies; Cardiotonic Agents; Chalcone; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Electrocardiography; Gene Expression Regulation; Hemodynamics; Male; Pigments, Biological; Quinones; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2008 |
Synthesis and antihyperglycemic activity of chalcone based aryloxypropanolamines.
Topics: Animals; Blood Glucose; Chalcone; Diabetes Mellitus, Experimental; Hyperglycemia; Hypoglycemic Agents; Male; Propanolamines; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship; Sucrose | 2004 |
Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues.
Topics: Aldehyde Reductase; Animals; Chalcone; Diabetes Mellitus, Experimental; Flavonoids; Free Radical Scavengers; Lens, Crystalline; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sorbitol; Streptozocin | 2001 |
The role of cyclic adenosine 3',5'-monophosphate and polyol metabolism in diabetic neuropathy.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Chalcone; Chalcones; Cyclic AMP; Cyclic GMP; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Iloprost; Inositol; Male; Neural Conduction; Rats; Rats, Inbred WKY; Rhodanine; Sciatic Nerve; Sorbitol; Thiazolidines | 1992 |
Effects of aldose reductase inhibitors on prostacyclin (PGI2) synthesis by aortic rings from rats with streptozotocin-induced diabetes.
Topics: Aldehyde Reductase; Animals; Aorta, Thoracic; Blood Glucose; Chalcone; Chalcones; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Epoprostenol; Male; Rats; Rats, Inbred Strains; Rhodanine; Sciatic Nerve; Sorbitol; Streptozocin; Sugar Alcohols; Thiazolidines | 1991 |
Isoliquiritigenin: a new aldose reductase inhibitor from glycyrrhizae radix.
Topics: Aldehyde Reductase; Animals; Chalcone; Chalcones; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Erythrocytes; Humans; Male; Molecular Structure; Plants, Medicinal; Propiophenones; Rats; Rats, Inbred Strains; Sorbitol; Sugar Alcohol Dehydrogenases | 1990 |