cgp 52411 has been researched along with Acute Confusional Senile Dementia in 5 studies
4,5-dianilinophthalimide: structure given in first source
4,5-dianilinophthalimide : Phthalimide substituted at the 4- and 5-positions by anilino groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We find that these protofibrils or fibrils are toxic to certain neuronal cells that carry Ca-permeant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors." | 1.32 | Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule. ( Blanchard, BJ; Chen, A; Ingram, VM; Rozeboom, LM; Stafford, KA; Weigele, P, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, XH | 1 |
| Qiao, JP | 1 |
| Yang, Y | 1 |
| Cui, MC | 1 |
| Zhou, JN | 1 |
| Liu, BL | 1 |
| Blanchard, BJ | 2 |
| Chen, A | 1 |
| Rozeboom, LM | 2 |
| Stafford, KA | 1 |
| Weigele, P | 2 |
| Ingram, VM | 2 |
| Doggrell, SA | 1 |
| Hennessy, EJ | 2 |
| Buchwald, SL | 2 |
| Wang, H | 1 |
| Duennwald, ML | 1 |
| Roberts, BE | 1 |
| Zhang, YL | 1 |
| Steele, AD | 1 |
| Krishnan, R | 1 |
| Su, LJ | 1 |
| Griffin, D | 1 |
| Mukhopadhyay, S | 1 |
| King, J | 1 |
| Deniz, AA | 1 |
| Lindquist, S | 1 |
| Shorter, J | 1 |
1 review available for cgp 52411 and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
A small-molecule lead compound for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cell Line; Drugs, Investigational; Humans; Phthalimides | 2005 |
4 other studies available for cgp 52411 and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Novel anilinophthalimide derivatives as potential probes for beta-amyloid plaque in the brain.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Brain; Humans; Mice; Phthalimi | 2010 |
Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Calcium Signaling; Drug Evaluation, Preclinical; Humans; I | 2004 |
Synthesis of 4,5-dianilinophthalimide and related analogues for potential treatment of Alzheimer's disease via palladium-catalyzed amination.
Topics: Alzheimer Disease; Amination; Catalysis; Palladium; Phthalimides | 2005 |
Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Biological Transport; Biophysics; Cysteine; Fluor | 2008 |