cgp 37157 has been researched along with Melanoma in 2 studies
CGP 37157: benzothiazepine derivative of clonazepam; inhibits the in vitro activity of mitochondrial sodium-calcium exchange
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohshima, Y | 1 |
| Takata, N | 1 |
| Suzuki-Karasaki, M | 1 |
| Yoshida, Y | 1 |
| Tokuhashi, Y | 1 |
| Suzuki-Karasaki, Y | 1 |
| Feldman, B | 1 |
| Fedida-Metula, S | 1 |
| Nita, J | 1 |
| Sekler, I | 1 |
| Fishman, D | 1 |
2 other studies available for cgp 37157 and Melanoma
| Article | Year |
|---|---|
Disrupting mitochondrial Ca2+ homeostasis causes tumor-selective TRAIL sensitization through mitochondrial network abnormalities.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Calcium; Cell Line, Tumor; Clonazepa | 2017 |
Coupling of mitochondria to store-operated Ca(2+)-signaling sustains constitutive activation of protein kinase B/Akt and augments survival of malignant melanoma cells.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cell Survival; Clonazepam; Flow Cytometry; Me | 2010 |