cgp 37157 has been researched along with Hyperuricemia in 1 studies
CGP 37157: benzothiazepine derivative of clonazepam; inhibits the in vitro activity of mitochondrial sodium-calcium exchange
Hyperuricemia: Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uric acid (UA) has proven to be a causal agent in endothelial dysfunction in which ROS production plays an important role." | 1.38 | Hyperuricemia induces endothelial dysfunction via mitochondrial Na+/Ca2+ exchanger-mediated mitochondrial calcium overload. ( Chen, X; Cui, S; Ding, R; Feng, Z; Fu, B; Hong, Q; Huang, Z; Qi, K; Wang, L; Wu, D; Yang, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hong, Q | 1 |
| Qi, K | 1 |
| Feng, Z | 1 |
| Huang, Z | 1 |
| Cui, S | 1 |
| Wang, L | 1 |
| Fu, B | 1 |
| Ding, R | 1 |
| Yang, J | 1 |
| Chen, X | 1 |
| Wu, D | 1 |
1 other study available for cgp 37157 and Hyperuricemia
| Article | Year |
|---|---|
Hyperuricemia induces endothelial dysfunction via mitochondrial Na+/Ca2+ exchanger-mediated mitochondrial calcium overload.
Topics: Calcium; Clonazepam; Cytoplasm; Endothelium; Human Umbilical Vein Endothelial Cells; Humans; Hydroge | 2012 |