cgp 37157 has been researched along with Heart Failure in 2 studies
CGP 37157: benzothiazepine derivative of clonazepam; inhibits the in vitro activity of mitochondrial sodium-calcium exchange
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dietl, A | 1 |
| Maack, C | 1 |
| Liu, T | 1 |
| Takimoto, E | 1 |
| Dimaano, VL | 1 |
| DeMazumder, D | 1 |
| Kettlewell, S | 1 |
| Smith, G | 1 |
| Sidor, A | 1 |
| Abraham, TP | 1 |
| O'Rourke, B | 1 |
1 review available for cgp 37157 and Heart Failure
| Article | Year |
|---|---|
Targeting Mitochondrial Calcium Handling and Reactive Oxygen Species in Heart Failure.
Topics: Antioxidants; Benzhydryl Compounds; Calcium; Clonazepam; Glucosides; Heart Failure; Humans; Mitochon | 2017 |
1 other study available for cgp 37157 and Heart Failure
| Article | Year |
|---|---|
Inhibiting mitochondrial Na+/Ca2+ exchange prevents sudden death in a Guinea pig model of heart failure.
Topics: Animals; Anti-Arrhythmia Agents; Calcium; Cardiomegaly; Clonazepam; Death, Sudden, Cardiac; Disease | 2014 |