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cgp 37157 and Encephalomyopathies, Mitochondrial

cgp 37157 has been researched along with Encephalomyopathies, Mitochondrial in 2 studies

CGP 37157: benzothiazepine derivative of clonazepam; inhibits the in vitro activity of mitochondrial sodium-calcium exchange

Research Excerpts

ExcerptRelevanceReference
"Treatment of MERRF cells with drugs affecting organellar Ca2+ transport mostly restored both the agonist-dependent mitochondrial Ca2+ uptake and the ensuing stimulation of ATP production."1.30A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency. ( Brini, M; Davidson, M; King, MP; Pinton, P; Rizzuto, R; Schon, EA, 1999)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Visch, HJ1
Rutter, GA1
Koopman, WJ1
Koenderink, JB1
Verkaart, S1
de Groot, T1
Varadi, A1
Mitchell, KJ1
van den Heuvel, LP1
Smeitink, JA1
Willems, PH1
Brini, M1
Pinton, P1
King, MP1
Davidson, M1
Schon, EA1
Rizzuto, R1

Other Studies

2 other studies available for cgp 37157 and Encephalomyopathies, Mitochondrial

ArticleYear
Inhibition of mitochondrial Na+-Ca2+ exchange restores agonist-induced ATP production and Ca2+ handling in human complex I deficiency.
    The Journal of biological chemistry, 2004, Sep-24, Volume: 279, Issue:39

    Topics: Adenosine Triphosphate; Bradykinin; Calcium; Cell Nucleus; Clonazepam; Cytosol; Electron Transport C

2004
A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency.
    Nature medicine, 1999, Volume: 5, Issue:8

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Calcium; Calcium Signaling; Cell Line; Clonazepam

1999