cgp 35348 has been researched along with Disease Models, Animal in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (34.38) | 18.2507 |
| 2000's | 10 (31.25) | 29.6817 |
| 2010's | 9 (28.13) | 24.3611 |
| 2020's | 2 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Gureviciene, I; Jin, N; Tanila, H; Ziyatdinova, S | 1 |
| Galanopoulou, AS; Li, Q; Liu, W; Moshé, SL; Mowrey, WB; Shandra, O | 1 |
| Eisenach, JC; Hayashida, K; Severino, AL; Suto, T | 1 |
| Bisht, R; Kumar, P; Majeed, AB; Pant, J; Prakash, A; Tyagi, RK | 1 |
| Carvalho, P; de Vries, MG; Martins, I; Tavares, I; Teixeira-Pinto, A; Westerink, BHC; Wilson, SP | 1 |
| Ali, M; Gillani, Q; Iqbal, F | 1 |
| Aleem, IS; Ashraf, A; Cortez, MA; Kanawaty, A; Liu, CC; Sadeghnia, HR; Shen, L; Snead, OC; Stewart, L; Trepanier, CH; Wu, Y | 1 |
| Dong, F; Jun, C; Liang, Y; Wei, H; Xiao, F; Yu, K | 1 |
| O'Rourke, ST; Qian, SY; Sun, C; Yao, F; Zhang, Q | 1 |
| Linderoth, B; Meyerson, BA; Song, Z; Ultenius, C | 1 |
| Mareš, P | 1 |
| Bernášková, K; Kubová, H; Mareš, P | 1 |
| Eisenach, JC; Hayashida, K; Kimura, M; Obata, H; Saito, S | 1 |
| Hulme, ME; Ritchie, GD; Rossi, J | 1 |
| Chapman, V; Sokal, DM | 1 |
| Delorey, TM; Handforth, A; Homanics, GE; Olsen, RW | 1 |
| Leung, LS; Tsai, ML | 1 |
| Burnham, WM; Chan, KF; Cortez, MA; Jia, Z; Snead, OC | 1 |
| Castro-Lopes, JM; Neto, FL; Potes, CS | 1 |
| Rees, H; Sluka, KA; Westlund, KN; Willis, WD | 1 |
| Sved, AF; Tsukamoto, K | 1 |
| Brailowsky, S; Di Scala, G; Meneses, S; Montiel, T | 1 |
| Fisher, RS; Smith, KA | 1 |
| Aizawa, M; Fukuda, H; Ito, Y | 1 |
| Fukuda, H; Ito, Y | 1 |
| Fukuda, H; Ishige, K; Ito, Y | 1 |
| Bose, P; Parmer, R; Reier, PJ; Thompson, FJ; Wang, DC | 1 |
| Snead, OC | 1 |
| Cao, Z; Clark, S; Hosford, DA; Huin, A; Lin, FH; Morrisett, RA; Wilson, WA | 1 |
| Bernasconi, R; Bittiger, H; Lauber, J; Leonhardt, T; Marescaux, C; Martin, P; Reymann, N; Rubio, V; Vergnes, M | 1 |
| Bernasconi, R; Marescaux, C; Vergnes, M | 1 |
1 review(s) available for cgp 35348 and Disease Models, Animal
| Article | Year |
|---|---|
[Pharmacology of the GABA receptor functions in the central nervous systems].
Topics: Animals; Central Nervous System; Disease Models, Animal; Epilepsy, Absence; GABA Antagonists; Humans; Mice; Organophosphorus Compounds; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Transcription Factors | 1998 |
31 other study(ies) available for cgp 35348 and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Response of spike-wave discharges in aged APP/PS1 Alzheimer model mice to antiepileptic, metabolic and cholinergic drugs.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Alzheimer Disease; Animals; Anticonvulsants; Atropine; Disease Models, Animal; Donepezil; Drug Administration Schedule; Electroencephalography; Epilepsy; Ethosuximide; GABA Antagonists; Humans; Injections, Intraperitoneal; Lactic Acid; Levetiracetam; Male; Mice; Mice, Transgenic; Nootropic Agents; Organophosphorus Compounds; Parasympatholytics; Plaque, Amyloid; Pyruvic Acid; Video Recording | 2020 |
Preclinical Screening for Treatments for Infantile Spasms in the Multiple Hit Rat Model of Infantile Spasms: An Update.
Topics: Animals; Anticonvulsants; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Estradiol; GABA Antagonists; Humans; Infant; Lipopolysaccharides; Male; Organophosphorus Compounds; para-Aminobenzoates; Random Allocation; Rats; Rats, Sprague-Dawley; Spasms, Infantile; Treatment Outcome | 2017 |
Gabapentin increases extracellular glutamatergic level in the locus coeruleus via astroglial glutamate transporter-dependent mechanisms.
Topics: Amines; Amino Acid Transport System X-AG; Animals; Astrocytes; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Locus Coeruleus; Male; Neuralgia; Norepinephrine; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Spinal Nerves; Time Factors | 2014 |
Possible role of GABA-B receptor modulation in MPTP induced Parkinson's disease in rats.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Baclofen; Cerebral Cortex; Corpus Striatum; Cytokines; Disease Models, Animal; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Lipid Peroxidation; Male; Motor Activity; Organophosphorus Compounds; Oxidative Stress; Parkinsonian Disorders; Rats, Wistar; Receptors, GABA-B; Rotarod Performance Test | 2015 |
GABA acting on GABAB receptors located in a medullary pain facilitatory area enhances nociceptive behaviors evoked by intraplantar formalin injection.
Topics: Animals; Baclofen; Disease Models, Animal; Formaldehyde; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Neurons; Nociception; Nociceptors; Organophosphorus Compounds; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, GABA-B; Reticular Formation | 2015 |
Effect of GABA
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Biomarkers; Brain; Disease Models, Animal; Female; GABA-B Receptor Antagonists; Hypoxia-Ischemia, Brain; Inflammation Mediators; Interleukin-18; Interleukin-6; Male; Mice; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Sex Factors | 2016 |
Infantile spasms and Down syndrome: a new animal model.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Baclofen; Brain; Disease Models, Animal; Down Syndrome; Electroencephalography; Ethosuximide; GABA Agonists; Genotype; Humans; Infant; Mice; Mice, Mutant Strains; Organophosphorus Compounds; Phenotype; Receptors, GABA-A; Receptors, GABA-B; Spasms, Infantile; Time Factors; Valproic Acid; Vigabatrin | 2009 |
The GABAB receptor inhibits activation of hepatic stellate cells.
Topics: Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Disease Progression; DNA; GABA Antagonists; GABA-B Receptor Agonists; Gene Expression; Hepatic Stellate Cells; Immunohistochemistry; Liver Cirrhosis; Male; Oligonucleotide Array Sequence Analysis; Organophosphorus Compounds; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2010 |
Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats.
Topics: Angiotensin II; Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Disease Models, Animal; GABA Agonists; GABA Antagonists; Hypertension; Infusion Pumps, Implantable; Male; Microinjections; Muscimol; NG-Nitroarginine Methyl Ester; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Time Factors; Up-Regulation | 2009 |
Pain relief by spinal cord stimulation involves serotonergic mechanisms: an experimental study in a rat model of mononeuropathy.
Topics: Animals; Area Under Curve; Behavior, Animal; Disease Models, Animal; Electric Stimulation Therapy; Electrodes, Implanted; Enzyme-Linked Immunosorbent Assay; GABA Antagonists; Gene Expression Regulation; Intercellular Signaling Peptides and Proteins; Male; Muscarinic Antagonists; Organophosphorus Compounds; Pain Measurement; Pain Threshold; Peptides; Rats; Rats, Sprague-Dawley; Sciatica; Serotonin; Spinal Cord; Time Factors; Vesicular Monoamine Transport Proteins | 2009 |
GABA-B receptor antagonist CGP 35348 interferes with an arrest of cortical epileptic afterdischarges in developing rats.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy; Evoked Potentials; GABA Antagonists; Organophosphorus Compounds; Rats; Rats, Wistar | 2010 |
An antagonist of GABA-B receptors potentiates activity of cortical epileptic foci.
Topics: Animals; Bicuculline; Brain Waves; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; GABA-B Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-B; Time Factors | 2012 |
Relief of hypersensitivity after nerve injury from systemic donepezil involves spinal cholinergic and γ-aminobutyric acid mechanisms.
Topics: Animals; Atropine; Bicuculline; Cholinergic Agents; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; GABA Agents; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Indans; Male; Mecamylamine; Neuralgia; Nicotinic Antagonists; Organophosphorus Compounds; Parasympatholytics; Peripheral Nerve Injuries; Piperidines; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2013 |
Treatment of spontaneous and chemically induced EEG paroxysms in the Fischer-344 rat with traditional antiepileptic drugs or AED+CGP 35348 polytherapy.
Topics: Aging; Animals; Anticonvulsants; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Male; Organophosphorus Compounds; Rats; Rats, Inbred F344 | 2003 |
Inhibitory effects of spinal baclofen on spinal dorsal horn neurones in inflamed and neuropathic rats in vivo.
Topics: Animals; Baclofen; Carrageenan; Disease Models, Animal; Electric Stimulation; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; Inflammation; Male; Organophosphorus Compounds; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Spinal Cord; Spinal Nerves | 2003 |
Pharmacologic evidence for abnormal thalamocortical functioning in GABA receptor beta3 subunit-deficient mice, a model of Angelman syndrome.
Topics: Angelman Syndrome; Animals; Anticonvulsants; Baclofen; Cerebral Cortex; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Ethosuximide; Female; GABA Agonists; GABA Antagonists; Humans; Male; Mice; Mice, Mutant Strains; Neural Pathways; Organophosphorus Compounds; Parietal Lobe; Receptors, GABA-A; Thalamus | 2005 |
Decrease of hippocampal GABA B receptor-mediated inhibition after hyperthermia-induced seizures in immature rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Dentate Gyrus; Disease Models, Animal; Electroencephalography; Excitatory Postsynaptic Potentials; Fever; GABA Antagonists; Hippocampus; Injections, Intraventricular; Neural Inhibition; Organophosphorus Compounds; Perforant Pathway; Rats; Rats, Long-Evans; Receptors, GABA-B; Seizures; Seizures, Febrile; Synaptic Transmission | 2006 |
GABAB receptor antagonism abolishes the learning impairments in rats with chronic atypical absence seizures.
Topics: Animals; Anticholesteremic Agents; Anticonvulsants; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Absence; Ethosuximide; Female; GABA Antagonists; GABA-B Receptor Antagonists; Hippocampus; Learning Disabilities; Maze Learning; Memory Disorders; Organophosphorus Compounds; Rats; Time Factors; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2006 |
Inhibition of pain behavior by GABA(B) receptors in the thalamic ventrobasal complex: effect on normal rats subjected to the formalin test of nociception.
Topics: Acute Disease; Analgesics; Animals; Baclofen; Behavior, Animal; Chronic Disease; Disease Models, Animal; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Neural Inhibition; Neurons; Organophosphorus Compounds; Pain; Pain Measurement; Pain Threshold; Rats; Receptors, GABA-B; Synaptic Transmission; Time Factors; Ventral Thalamic Nuclei | 2006 |
The role of glutamate and GABA receptors in the generation of dorsal root reflexes by acute arthritis in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Arthritis; Bicuculline; Disease Models, Animal; GABA-B Receptor Antagonists; Inflammation; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Glutamate; Spinal Nerve Roots; Time Factors | 1995 |
Enhanced gamma-aminobutyric acid-mediated responses in nucleus tractus solitarius of hypertensive rats.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Analysis of Variance; Animals; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; GABA-B Receptor Antagonists; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Male; Neurotransmitter Agents; Nipecotic Acids; Organophosphorus Compounds; Pressoreceptors; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-B; Sodium Chloride; Solitary Nucleus; Vigabatrin | 1993 |
Effects of GABAB receptor antagonists on two models of focal epileptogenesis.
Topics: Animals; Baclofen; Disease Models, Animal; Epilepsies, Partial; GABA Antagonists; GABA-B Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Time Factors | 1995 |
The selective GABAB antagonist CGP-35348 blocks spike-wave bursts in the cholesterol synthesis rat absence epilepsy model.
Topics: Animals; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Epilepsy, Absence; GABA Antagonists; Male; Organophosphorus Compounds; Rats; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 1996 |
Pharmacological profiles of generalized absence seizures in lethargic, stargazer and gamma-hydroxybutyrate-treated model mice.
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Epilepsy, Generalized; Female; GABA Antagonists; Male; Mice; Mice, Neurologic Mutants; Organophosphorus Compounds; Phosphinic Acids; Sodium Oxybate | 1997 |
Pharmacological profiles of absence seizure-induced increases in CRE- and AP-1 DNA-binding activities in gamma-butyrolactone-treated mice.
Topics: 4-Butyrolactone; Activating Transcription Factor 2; Animals; Anticonvulsants; Brain; Brain Chemistry; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; DNA-Binding Proteins; Epilepsy, Absence; Ethosuximide; GABA Antagonists; Mice; Organophosphorus Compounds; Phosphinic Acids; Thalamus; Transcription Factor AP-1; Transcription Factors | 1998 |
Scientific basis of spasticity: insights from a laboratory model.
Topics: Animals; Calcium Channels; Disease Models, Animal; GABA Antagonists; Humans; Interneurons; Muscle Spasticity; Neurons, Afferent; Organophosphorus Compounds; Presynaptic Terminals; Receptors, GABA-A; Spinal Cord Compression; Spinal Cord Injuries | 2001 |
Evidence for GABAB-mediated mechanisms in experimental generalized absence seizures.
Topics: Animals; Baclofen; Behavior, Animal; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; GABA-A Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice.
Topics: Animals; Anticonvulsants; Baclofen; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Electrophysiology; Epilepsy, Absence; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Picrotoxin; Quinoxalines; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1992 |
Experimental absence seizures: potential role of gamma-hydroxybutyric acid and GABAB receptors.
Topics: 4-Butyrolactone; Animals; Baclofen; Brain; Cyclic GMP; Disease Models, Animal; Epilepsy, Absence; GABA-A Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Reproducibility of Results; Sodium Oxybate; Valproic Acid | 1992 |
GABAB receptor antagonists: potential new anti-absence drugs.
Topics: Action Potentials; Administration, Oral; Animals; Baclofen; Blood-Brain Barrier; Disease Models, Animal; Epilepsy, Absence; GABA-A Receptor Antagonists; Injections, Intraperitoneal; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains | 1992 |