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cgp 12177 and Lymphoma

cgp 12177 has been researched along with Lymphoma in 3 studies

CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.

Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.

Research Excerpts

ExcerptRelevanceReference
"The ability of the atypical agonists celiprolol and pindolol to induce sequestration and down regulation of beta adrenergic receptors was investigated in S49 lymphoma cells."3.67Down regulation of beta adrenergic receptors in S49 lymphoma cells induced by atypical agonists. ( Molinoff, PB; Reynolds, EE, 1986)
"Bromoacetylalprenololmenthane was found to inhibit hormone-induced beta-adrenergic receptor internalization in a dose-dependent fashion in S49 lymphoma cells, besides its known ability to bind to beta-receptors irreversibly."3.67Bromoacetylalprenololmenthane binding to beta-receptors modulates the rate of hormone-induced internalization but not desensitization in S49 cells. ( Box, RJ; Staehelin, M, 1987)
" In two cell lines, C6 glioma and WEHI 7 lymphoma cells, -50% of the cell surface receptors disappear within minutes of incubation of the cells with isoproterenol."3.66Rapid and reversible disappearance of beta-adrenergic cell surface receptors. ( Simons, P; Staehelin, M, 1982)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Staehelin, M2
Simons, P1
Reynolds, EE1
Molinoff, PB1
Box, RJ1

Other Studies

3 other studies available for cgp 12177 and Lymphoma

ArticleYear
Rapid and reversible disappearance of beta-adrenergic cell surface receptors.
    The EMBO journal, 1982, Volume: 1, Issue:2

    Topics: Animals; Cell Line; Endocytosis; Glioma; Isoproterenol; Lymphoma; Propanolamines; Receptors, Adrener

1982
Down regulation of beta adrenergic receptors in S49 lymphoma cells induced by atypical agonists.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Binding Sites; Celiprolol; Cell Division; Cell Line; Isoprotereno

1986
Bromoacetylalprenololmenthane binding to beta-receptors modulates the rate of hormone-induced internalization but not desensitization in S49 cells.
    FEBS letters, 1987, Apr-20, Volume: 214, Issue:2

    Topics: Alprenolol; Cell Line; Cell Membrane; Cyclic AMP; Isoproterenol; Kinetics; Lymphoma; Propanolamines;

1987