cgp 12177 has been researched along with Lymphoma in 3 studies
CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.
Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ability of the atypical agonists celiprolol and pindolol to induce sequestration and down regulation of beta adrenergic receptors was investigated in S49 lymphoma cells." | 3.67 | Down regulation of beta adrenergic receptors in S49 lymphoma cells induced by atypical agonists. ( Molinoff, PB; Reynolds, EE, 1986) |
| "Bromoacetylalprenololmenthane was found to inhibit hormone-induced beta-adrenergic receptor internalization in a dose-dependent fashion in S49 lymphoma cells, besides its known ability to bind to beta-receptors irreversibly." | 3.67 | Bromoacetylalprenololmenthane binding to beta-receptors modulates the rate of hormone-induced internalization but not desensitization in S49 cells. ( Box, RJ; Staehelin, M, 1987) |
| " In two cell lines, C6 glioma and WEHI 7 lymphoma cells, -50% of the cell surface receptors disappear within minutes of incubation of the cells with isoproterenol." | 3.66 | Rapid and reversible disappearance of beta-adrenergic cell surface receptors. ( Simons, P; Staehelin, M, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Staehelin, M | 2 |
| Simons, P | 1 |
| Reynolds, EE | 1 |
| Molinoff, PB | 1 |
| Box, RJ | 1 |
3 other studies available for cgp 12177 and Lymphoma
| Article | Year |
|---|---|
Rapid and reversible disappearance of beta-adrenergic cell surface receptors.
Topics: Animals; Cell Line; Endocytosis; Glioma; Isoproterenol; Lymphoma; Propanolamines; Receptors, Adrener | 1982 |
Down regulation of beta adrenergic receptors in S49 lymphoma cells induced by atypical agonists.
Topics: Adrenergic beta-Agonists; Animals; Binding Sites; Celiprolol; Cell Division; Cell Line; Isoprotereno | 1986 |
Bromoacetylalprenololmenthane binding to beta-receptors modulates the rate of hormone-induced internalization but not desensitization in S49 cells.
Topics: Alprenolol; Cell Line; Cell Membrane; Cyclic AMP; Isoproterenol; Kinetics; Lymphoma; Propanolamines; | 1987 |