cgp 12177 has been researched along with Heart Failure in 9 studies
CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Excerpt | Relevance | Reference |
---|---|---|
"Xamoterol was considerably less effective than isoproterenol in stimulating adenylate cyclase activity but the difference was narrowed by 1 microM forskolin, presumably by inducing more efficient coupling to the catalytic subunit of the enzyme." | 1.28 | Effects of xamoterol on the reversible cycling of cardiac beta-adrenoceptors. ( Limas, C; Limas, CJ, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (33.33) | 18.2507 |
2000's | 4 (44.44) | 29.6817 |
2010's | 2 (22.22) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kiriazis, H | 1 |
Tugiono, N | 1 |
Xu, Q | 1 |
Gao, XM | 1 |
Jennings, NL | 1 |
Ming, Z | 1 |
Su, Y | 1 |
Klenowski, P | 1 |
Summers, RJ | 1 |
Kaumann, A | 1 |
Molenaar, P | 1 |
Du, XJ | 1 |
Gaemperli, O | 1 |
Liga, R | 1 |
Spyrou, N | 1 |
Rosen, SD | 1 |
Foale, R | 1 |
Kooner, JS | 1 |
Rimoldi, OE | 1 |
Camici, PG | 1 |
Tsukamoto, T | 1 |
Morita, K | 1 |
Naya, M | 1 |
Inubushi, M | 1 |
Katoh, C | 1 |
Nishijima, K | 1 |
Kuge, Y | 1 |
Okamoto, H | 1 |
Tsutsui, H | 1 |
Tamaki, N | 1 |
Steinfath, M | 1 |
Lavicky, J | 1 |
Schmitz, W | 1 |
Scholz, H | 1 |
Döring, V | 1 |
Kalmár, P | 1 |
Re, G | 1 |
Bergamasco, L | 1 |
Badino, P | 1 |
Borgarelli, M | 1 |
Odore, R | 1 |
Tarducci, A | 1 |
Zanatta, R | 1 |
Girardi, C | 1 |
Yonemochi, H | 1 |
Yasunaga, S | 1 |
Teshima, Y | 1 |
Takahashi, N | 1 |
Nakagawa, M | 1 |
Ito, M | 1 |
Saikawa, T | 1 |
de Jong, RM | 1 |
Blanksma, PK | 1 |
van Waarde, A | 1 |
van Veldhuisen, DJ | 1 |
Schäfers, M | 1 |
Riemann, B | 1 |
Levkau, B | 1 |
Wichter, T | 1 |
Schäfers, K | 1 |
Kopka, K | 1 |
Breithardt, G | 1 |
Schober, O | 1 |
Limas, CJ | 1 |
Limas, C | 1 |
1 review available for cgp 12177 and Heart Failure
Article | Year |
---|---|
Measurement of myocardial beta-adrenoceptor density in clinical studies: a role for positron emission tomography?
Topics: Carbon Radioisotopes; Heart; Heart Failure; Humans; Myocardial Contraction; Myocardium; Propanolamin | 2002 |
8 other studies available for cgp 12177 and Heart Failure
Article | Year |
---|---|
Chronic activation of the low affinity site of β1-adrenoceptors stimulates haemodynamics but exacerbates pressure-overload cardiac remodelling.
Topics: Adrenergic beta-Antagonists; Animals; Binding Sites; Cardiomegaly; Disease Models, Animal; Disease P | 2013 |
Myocardial beta-adrenoceptor down-regulation early after infarction is associated with long-term incidence of congestive heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Coronary Circulation; Down-Regulation; Female; Heart; Heart Fail | 2010 |
Decreased myocardial beta-adrenergic receptor density in relation to increased sympathetic tone in patients with nonischemic cardiomyopathy.
Topics: 3-Iodobenzylguanidine; Aged; Carbon Radioisotopes; Cardiomyopathies; Female; Heart; Heart Failure; H | 2007 |
Changes in cardiac beta-adrenoceptors in human heart diseases: relationship to the degree of heart failure and further evidence for etiology-related regulation of beta 1 and beta 2 subtypes.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aortic Valve; Cardiomyopathy, Hypertrophic; Down-Reg | 1993 |
Canine dilated cardiomyopathy: lymphocyte and cardiac alpha(1)- and beta-adrenoceptor concentrations in normal and affected great danes.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomyopathy, Dilated; Catecho | 1999 |
Rapid electrical stimulation of contraction reduces the density of beta-adrenergic receptors and responsiveness of cultured neonatal rat cardiomyocytes. Possible involvement of microtubule disassembly secondary to mechanical stress.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Ant | 2000 |
Current status and future applications of cardiac receptor imaging with positron emission tomography.
Topics: Adrenergic beta-Antagonists; Arteriosclerosis; Carbon Radioisotopes; Heart Failure; Humans; Myocardi | 2002 |
Effects of xamoterol on the reversible cycling of cardiac beta-adrenoceptors.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cell-Free System; | 1990 |