cgp 12177 has been researched along with Dermatitis, Atopic in 1 studies
CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.
Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
| Excerpt | Relevance | Reference |
|---|---|---|
| "DNA sequence analysis of nine atopic eczema patients confirmed a substitution in codon (1618) GCC (Ala(119)) to GAC (Asp(119))." | 1.34 | Structural and functional alterations in the beta2-adrenoceptor are caused by a point mutation in patients with atopic eczema. ( Gibbons, NC; Pittelkow, MR; Schallreuter, KU; Swanson, NN; Wei, Y; Wood, JM, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schallreuter, KU | 1 |
| Wei, Y | 1 |
| Pittelkow, MR | 1 |
| Swanson, NN | 1 |
| Gibbons, NC | 1 |
| Wood, JM | 1 |
1 other study available for cgp 12177 and Dermatitis, Atopic
| Article | Year |
|---|---|
Structural and functional alterations in the beta2-adrenoceptor are caused by a point mutation in patients with atopic eczema.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Amino Acid Sequence; Amino Acid Substitution; Base S | 2007 |