cgp 12177 has been researched along with Cardiac Failure in 9 studies
CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Xamoterol was considerably less effective than isoproterenol in stimulating adenylate cyclase activity but the difference was narrowed by 1 microM forskolin, presumably by inducing more efficient coupling to the catalytic subunit of the enzyme." | 1.28 | Effects of xamoterol on the reversible cycling of cardiac beta-adrenoceptors. ( Limas, C; Limas, CJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kiriazis, H | 1 |
| Tugiono, N | 1 |
| Xu, Q | 1 |
| Gao, XM | 1 |
| Jennings, NL | 1 |
| Ming, Z | 1 |
| Su, Y | 1 |
| Klenowski, P | 1 |
| Summers, RJ | 1 |
| Kaumann, A | 1 |
| Molenaar, P | 1 |
| Du, XJ | 1 |
| Gaemperli, O | 1 |
| Liga, R | 1 |
| Spyrou, N | 1 |
| Rosen, SD | 1 |
| Foale, R | 1 |
| Kooner, JS | 1 |
| Rimoldi, OE | 1 |
| Camici, PG | 1 |
| Tsukamoto, T | 1 |
| Morita, K | 1 |
| Naya, M | 1 |
| Inubushi, M | 1 |
| Katoh, C | 1 |
| Nishijima, K | 1 |
| Kuge, Y | 1 |
| Okamoto, H | 1 |
| Tsutsui, H | 1 |
| Tamaki, N | 1 |
| Steinfath, M | 1 |
| Lavicky, J | 1 |
| Schmitz, W | 1 |
| Scholz, H | 1 |
| Döring, V | 1 |
| Kalmár, P | 1 |
| Re, G | 1 |
| Bergamasco, L | 1 |
| Badino, P | 1 |
| Borgarelli, M | 1 |
| Odore, R | 1 |
| Tarducci, A | 1 |
| Zanatta, R | 1 |
| Girardi, C | 1 |
| Yonemochi, H | 1 |
| Yasunaga, S | 1 |
| Teshima, Y | 1 |
| Takahashi, N | 1 |
| Nakagawa, M | 1 |
| Ito, M | 1 |
| Saikawa, T | 1 |
| de Jong, RM | 1 |
| Blanksma, PK | 1 |
| van Waarde, A | 1 |
| van Veldhuisen, DJ | 1 |
| Schäfers, M | 1 |
| Riemann, B | 1 |
| Levkau, B | 1 |
| Wichter, T | 1 |
| Schäfers, K | 1 |
| Kopka, K | 1 |
| Breithardt, G | 1 |
| Schober, O | 1 |
| Limas, CJ | 1 |
| Limas, C | 1 |
1 review available for cgp 12177 and Cardiac Failure
| Article | Year |
|---|---|
Measurement of myocardial beta-adrenoceptor density in clinical studies: a role for positron emission tomography?
Topics: Carbon Radioisotopes; Heart; Heart Failure; Humans; Myocardial Contraction; Myocardium; Propanolamin | 2002 |
8 other studies available for cgp 12177 and Cardiac Failure
| Article | Year |
|---|---|
Chronic activation of the low affinity site of β1-adrenoceptors stimulates haemodynamics but exacerbates pressure-overload cardiac remodelling.
Topics: Adrenergic beta-Antagonists; Animals; Binding Sites; Cardiomegaly; Disease Models, Animal; Disease P | 2013 |
Myocardial beta-adrenoceptor down-regulation early after infarction is associated with long-term incidence of congestive heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Coronary Circulation; Down-Regulation; Female; Heart; Heart Fail | 2010 |
Decreased myocardial beta-adrenergic receptor density in relation to increased sympathetic tone in patients with nonischemic cardiomyopathy.
Topics: 3-Iodobenzylguanidine; Aged; Carbon Radioisotopes; Cardiomyopathies; Female; Heart; Heart Failure; H | 2007 |
Changes in cardiac beta-adrenoceptors in human heart diseases: relationship to the degree of heart failure and further evidence for etiology-related regulation of beta 1 and beta 2 subtypes.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aortic Valve; Cardiomyopathy, Hypertrophic; Down-Reg | 1993 |
Canine dilated cardiomyopathy: lymphocyte and cardiac alpha(1)- and beta-adrenoceptor concentrations in normal and affected great danes.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomyopathy, Dilated; Catecho | 1999 |
Rapid electrical stimulation of contraction reduces the density of beta-adrenergic receptors and responsiveness of cultured neonatal rat cardiomyocytes. Possible involvement of microtubule disassembly secondary to mechanical stress.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Ant | 2000 |
Current status and future applications of cardiac receptor imaging with positron emission tomography.
Topics: Adrenergic beta-Antagonists; Arteriosclerosis; Carbon Radioisotopes; Heart Failure; Humans; Myocardi | 2002 |
Effects of xamoterol on the reversible cycling of cardiac beta-adrenoceptors.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cell-Free System; | 1990 |