cgp 12177 has been researched along with Astrocytoma in 3 studies
CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ligand-induced internalization of beta-adrenergic receptors and the receptor-mediated internalization of epidermal growth factor were blocked, under similar conditions, by phenylarsine oxide (PAO) in human astrocytoma cells (1321N1)." | 7.67 | A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide. ( Coulter, SJ; Hertel, C; Perkins, JP, 1985) |
| "The ligand-induced internalization of beta-adrenergic receptors and the receptor-mediated internalization of epidermal growth factor were blocked, under similar conditions, by phenylarsine oxide (PAO) in human astrocytoma cells (1321N1)." | 3.67 | A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide. ( Coulter, SJ; Hertel, C; Perkins, JP, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Toll, L | 1 |
| Jimenez, L | 1 |
| Waleh, N | 1 |
| Jozwiak, K | 1 |
| Woo, AY | 1 |
| Xiao, RP | 1 |
| Bernier, M | 1 |
| Wainer, IW | 1 |
| Toews, ML | 1 |
| Waldo, GL | 1 |
| Harden, TK | 1 |
| Perkins, JP | 2 |
| Hertel, C | 1 |
| Coulter, SJ | 1 |
3 other studies available for cgp 12177 and Astrocytoma
| Article | Year |
|---|---|
{Beta}2-adrenergic receptor agonists inhibit the proliferation of 1321N1 astrocytoma cells.
Topics: Adrenergic beta-2 Receptor Agonists; Astrocytoma; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; | 2011 |
Relationship between an altered membrane form and a low affinity form of the beta-adrenergic receptor occurring during catecholamine-induced desensitization. Evidence for receptor internalization.
Topics: Astrocytoma; Cell Line; Centrifugation, Density Gradient; Concanavalin A; Humans; Isoproterenol; Met | 1984 |
A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide.
Topics: Adenosine Triphosphate; Arsenicals; Astrocytoma; Catecholamines; Cell Line; Dithiothreitol; Endocyto | 1985 |