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cgp 12177 and Astrocytoma

cgp 12177 has been researched along with Astrocytoma in 3 studies

CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research Excerpts

ExcerptRelevanceReference
"The ligand-induced internalization of beta-adrenergic receptors and the receptor-mediated internalization of epidermal growth factor were blocked, under similar conditions, by phenylarsine oxide (PAO) in human astrocytoma cells (1321N1)."7.67A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide. ( Coulter, SJ; Hertel, C; Perkins, JP, 1985)
"The ligand-induced internalization of beta-adrenergic receptors and the receptor-mediated internalization of epidermal growth factor were blocked, under similar conditions, by phenylarsine oxide (PAO) in human astrocytoma cells (1321N1)."3.67A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide. ( Coulter, SJ; Hertel, C; Perkins, JP, 1985)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Toll, L1
Jimenez, L1
Waleh, N1
Jozwiak, K1
Woo, AY1
Xiao, RP1
Bernier, M1
Wainer, IW1
Toews, ML1
Waldo, GL1
Harden, TK1
Perkins, JP2
Hertel, C1
Coulter, SJ1

Other Studies

3 other studies available for cgp 12177 and Astrocytoma

ArticleYear
{Beta}2-adrenergic receptor agonists inhibit the proliferation of 1321N1 astrocytoma cells.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 336, Issue:2

    Topics: Adrenergic beta-2 Receptor Agonists; Astrocytoma; Cell Line, Tumor; Cell Proliferation; Cyclic AMP;

2011
Relationship between an altered membrane form and a low affinity form of the beta-adrenergic receptor occurring during catecholamine-induced desensitization. Evidence for receptor internalization.
    The Journal of biological chemistry, 1984, Oct-10, Volume: 259, Issue:19

    Topics: Astrocytoma; Cell Line; Centrifugation, Density Gradient; Concanavalin A; Humans; Isoproterenol; Met

1984
A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide.
    The Journal of biological chemistry, 1985, Oct-15, Volume: 260, Issue:23

    Topics: Adenosine Triphosphate; Arsenicals; Astrocytoma; Catecholamines; Cell Line; Dithiothreitol; Endocyto

1985