cgp 12177 has been researched along with Arrhythmias, Cardiac in 2 studies
CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Beta4-Adrenoceptors mediate arrhythmias with smaller Ca2+ transients and smaller increases of L-type Ca2+ current than beta1-adrenoceptors, in line with different but still unknown mechanisms as previously suggested for the intact heart." | 1.30 | Beta4-adrenoceptors are more effective than beta1-adrenoceptors in mediating arrhythmic Ca2+ transients in mouse ventricular myocytes. ( Brown, D; Freestone, NS; Heubach, JF; Kaumann, AJ; Ravens, U; Wettwer, E, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freestone, NS | 2 |
| Heubach, JF | 1 |
| Wettwer, E | 1 |
| Ravens, U | 1 |
| Brown, D | 1 |
| Kaumann, AJ | 2 |
| Sarsero, D | 1 |
| Molenaar, P | 1 |
2 other studies available for cgp 12177 and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Beta4-adrenoceptors are more effective than beta1-adrenoceptors in mediating arrhythmic Ca2+ transients in mouse ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhyth | 1999 |
Putative beta 4-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (-)-[3H]-CGP 12177 binding.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhyth | 1999 |