Page last updated: 2024-10-24

cgp 12177 and Arrhythmia

cgp 12177 has been researched along with Arrhythmia in 2 studies

CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.

Research Excerpts

ExcerptRelevanceReference
"Beta4-Adrenoceptors mediate arrhythmias with smaller Ca2+ transients and smaller increases of L-type Ca2+ current than beta1-adrenoceptors, in line with different but still unknown mechanisms as previously suggested for the intact heart."1.30Beta4-adrenoceptors are more effective than beta1-adrenoceptors in mediating arrhythmic Ca2+ transients in mouse ventricular myocytes. ( Brown, D; Freestone, NS; Heubach, JF; Kaumann, AJ; Ravens, U; Wettwer, E, 1999)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Freestone, NS2
Heubach, JF1
Wettwer, E1
Ravens, U1
Brown, D1
Kaumann, AJ2
Sarsero, D1
Molenaar, P1

Other Studies

2 other studies available for cgp 12177 and Arrhythmia

ArticleYear
Beta4-adrenoceptors are more effective than beta1-adrenoceptors in mediating arrhythmic Ca2+ transients in mouse ventricular myocytes.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhyth

1999
Putative beta 4-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (-)-[3H]-CGP 12177 binding.
    British journal of pharmacology, 1999, Volume: 128, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhyth

1999