cetylpyridinium has been researched along with Pharyngitis in 13 studies
Cetylpyridinium: Cationic bactericidal surfactant used as a topical antiseptic for skin, wounds, mucous membranes, instruments, etc.; and also as a component in mouthwash and lozenges.
Pharyngitis: Inflammation of the throat (PHARYNX).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy and safety of a combined topical drug with flurbiprofen and cetylpyridinium chloride in patients with sore throat caused by upper respiratory tract infections." | 9.51 | [Results of a clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat]. ( Galustyan, AN; Gonik, MI; Sedavnykh, IS, 2022) |
| "To evaluate the efficacy and safety of a combined topical drug with flurbiprofen and cetylpyridinium chloride compared with a monocomponent drug in patients with sore throat associated with manifestations of acute pharyngitis, tonsillitis or with exacerbation of chronic forms of pharyngitis or tonsillitis." | 9.51 | [Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat]. ( Galustyan, AN; Poromov, AA; Sedavnykh, IS, 2022) |
| "Lozenges containing lidocaine and cetylpyridinium chloride (CPC) are commonly used for the treatment of sore throat." | 9.27 | Efficacy of 8 mg lidocaine and 2 mg cetylpyridinium chloride (CPC) fixed-combination lozenges on sore throat pain intensity compared with 1 mg lidocaine and 2 mg CPC fixed-combination lozenges in subjects with sore throat due to upper respiratory tract in ( Donath, F; Furcha, R; Garreffa, S; Mallefet, P, 2018) |
| "To evaluate the efficacy and safety of a combined topical drug with flurbiprofen and cetylpyridinium chloride in patients with sore throat caused by upper respiratory tract infections." | 5.51 | [Results of a clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat]. ( Galustyan, AN; Gonik, MI; Sedavnykh, IS, 2022) |
| "To evaluate the efficacy and safety of a combined topical drug with flurbiprofen and cetylpyridinium chloride compared with a monocomponent drug in patients with sore throat associated with manifestations of acute pharyngitis, tonsillitis or with exacerbation of chronic forms of pharyngitis or tonsillitis." | 5.51 | [Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat]. ( Galustyan, AN; Poromov, AA; Sedavnykh, IS, 2022) |
| "Lozenges containing lidocaine and cetylpyridinium chloride (CPC) are commonly used for the treatment of sore throat." | 5.27 | Efficacy of 8 mg lidocaine and 2 mg cetylpyridinium chloride (CPC) fixed-combination lozenges on sore throat pain intensity compared with 1 mg lidocaine and 2 mg CPC fixed-combination lozenges in subjects with sore throat due to upper respiratory tract in ( Donath, F; Furcha, R; Garreffa, S; Mallefet, P, 2018) |
| " The data on the use of the drug Grammidin based on a local broad-spectrum antibiotic gramicidin C and antiseptic cetylpyridinium chloride, as well as data from clinical studies of the effectiveness of the drug in the treatment of acute tonsillopharyngitis in children and adults are presented." | 3.91 | [Efficacy of topical drugs in the treatment of patients with acute inflammatory diseases of the pharynx]. ( Nikiforova, GN; Shevchik, EA; Svistushkin, VM; Toporkova, LA, 2019) |
| "Prior influenza vaccination had no effect on study outcome." | 2.84 | Randomized, double-blind, placebo-controlled clinical trial to assess the safety and effectiveness of a novel dual-action oral topical formulation against upper respiratory infections. ( Adkins, I; Arters, K; Buchheit, K; Esper, F; Ghannoum, MA; Mukherjee, PK; Salata, RA, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Galustyan, AN | 4 |
| Sedavnykh, IS | 4 |
| Gonik, MI | 1 |
| Poromov, AA | 3 |
| Svistushkin, VM | 1 |
| Nikiforova, GN | 1 |
| Shevchik, EA | 1 |
| Toporkova, LA | 1 |
| Xu, H | 1 |
| Zou, G | 1 |
| Zhang, X | 1 |
| Donath, F | 1 |
| Mallefet, P | 1 |
| Garreffa, S | 1 |
| Furcha, R | 1 |
| Wu, MH | 1 |
| Cheng, Y | 1 |
| Wang, TY | 1 |
| Ji, JF | 1 |
| Xue, F | 1 |
| Yu, X | 1 |
| Mukherjee, PK | 1 |
| Esper, F | 1 |
| Buchheit, K | 1 |
| Arters, K | 1 |
| Adkins, I | 1 |
| Ghannoum, MA | 1 |
| Salata, RA | 1 |
| Stricker, G | 1 |
| Ravanelli, O | 1 |
| Vorberg, G | 1 |
| Willenberg, W | 1 |
| Janecke, JB | 1 |
| Kuhnke, I | 1 |
| Sprenger, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-blind, Parallel Group, Single-dose Study of the Efficacy of Lidocaine 8 mg + Cetylpyridinium Chloride (CPC) 2 mg Fixed Combination Lozenges on Sore Throat Pain Intensity Compared to Lozenges Containing Lidocaine 1 mg and CPC 2 mg in S[NCT01265446] | Phase 3 | 250 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| A Pilot Study of the Safety, Tolerability, and Effectiveness of Halo to Prevent Acute Upper Respiratory Disease and Respiratory Virus Infections[NCT02644135] | 100 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
100 milimeter (mm) visual acuity score (left=no pain=0mm, right=worst possible pain=100mm) (NCT01265446)
Timeframe: Baseline and 2 hours post-dose
| Intervention | mm (Mean) |
|---|---|
| Lidocaine 8mg +CPC 2mg | -27.4 |
| Lidocaine 1mg + CPC 2mg | -26.9 |
100 milimeter (mm) visual acuity score (left=no pain=0mm, right=worst possible pain=100mm). It measures the highest pain level felt by the patient. (NCT01265446)
Timeframe: Baseline and 240 mn post-dose
| Intervention | mm (Mean) |
|---|---|
| Lidocaine 8mg +CPC 2mg | -25.5 |
| Lidocaine 1mg + CPC 2mg | -29.1 |
Measured by medical record review. (NCT02644135)
Timeframe: Through study duration, an average of 3 months
| Intervention | Number of acute respiratory illnesses (Number) |
|---|---|
| Halo Oral Spray | 4 |
| Halo Placebo | 2 |
(NCT02644135)
Timeframe: Through study duration, an average of 3 months
| Intervention | participants (Number) |
|---|---|
| Halo Oral Spray | 2 |
| Halo Placebo | 4 |
8 trials available for cetylpyridinium and Pharyngitis
| Article | Year |
|---|---|
[Results of a clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat].
Topics: Adult; Cetylpyridinium; Double-Blind Method; Flurbiprofen; Humans; Hyperemia; Pain; Pharyngitis; Pro | 2022 |
[Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat].
Topics: Adult; Cetylpyridinium; Double-Blind Method; Flurbiprofen; Humans; Hyperemia; Pain; Pain Measurement | 2022 |
[Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat].
Topics: Adult; Cetylpyridinium; Double-Blind Method; Flurbiprofen; Humans; Hyperemia; Pain; Pain Measurement | 2022 |
[Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat].
Topics: Adult; Cetylpyridinium; Double-Blind Method; Flurbiprofen; Humans; Hyperemia; Pain; Pain Measurement | 2022 |
[Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat].
Topics: Adult; Cetylpyridinium; Double-Blind Method; Flurbiprofen; Humans; Hyperemia; Pain; Pain Measurement | 2022 |
[Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat].
Topics: Adult; Cetylpyridinium; Double-Blind Method; Flurbiprofen; Humans; Hyperemia; Pain; Pain Measurement | 2022 |
[Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat].
Topics: Adult; Cetylpyridinium; Double-Blind Method; Flurbiprofen; Humans; Hyperemia; Pain; Pain Measurement | 2022 |
[Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat].
Topics: Adult; Cetylpyridinium; Double-Blind Method; Flurbiprofen; Humans; Hyperemia; Pain; Pain Measurement | 2022 |
[Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat].
Topics: Adult; Cetylpyridinium; Double-Blind Method; Flurbiprofen; Humans; Hyperemia; Pain; Pain Measurement | 2022 |
[Results of the clinical study of the combination of flurbiprofen and cetylpyridinium chloride in patients with sore throat].
Topics: Adult; Cetylpyridinium; Double-Blind Method; Flurbiprofen; Humans; Hyperemia; Pain; Pain Measurement | 2022 |
Efficacy of 8 mg lidocaine and 2 mg cetylpyridinium chloride (CPC) fixed-combination lozenges on sore throat pain intensity compared with 1 mg lidocaine and 2 mg CPC fixed-combination lozenges in subjects with sore throat due to upper respiratory tract in
Topics: Administration, Oral; Adult; Anesthetics, Local; Anti-Infective Agents, Local; Cetylpyridinium; Doub | 2018 |
Randomized, double-blind, placebo-controlled clinical trial to assess the safety and effectiveness of a novel dual-action oral topical formulation against upper respiratory infections.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Anti-Infective Agents, Local; Cety | 2017 |
[Treatment of inflammatory diseases in the mouth and pharynx using Imposit].
Topics: Administration, Topical; Adolescent; Adult; Aged; Aminobenzoates; Anti-Inflammatory Agents; Benzyl C | 1975 |
[Treatment of inflammatory lesions of the mouth and pharynx using Imposit].
Topics: Adolescent; Adult; Aged; Cetylpyridinium; Child; Clinical Trials as Topic; Drug Combinations; Drug E | 1977 |
The local anaesthetic effects of cepacaine in post-tonsillectomy cases, pharyngitis and minor infections of the mouth.
Topics: Adult; Anesthetics, Local; Benzocaine; Cetylpyridinium; Clinical Trials as Topic; Dibucaine; Drug Co | 1976 |
[Results of testing a new drug in form of sore throat tablets].
Topics: Anti-Infective Agents, Local; Bacitracin; Cetylpyridinium; Clinical Trials as Topic; Drug Combinatio | 1975 |
5 other studies available for cetylpyridinium and Pharyngitis
| Article | Year |
|---|---|
[Efficacy of topical drugs in the treatment of patients with acute inflammatory diseases of the pharynx].
Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Anti-Infective Agents, Local; Cetylpyridinium | 2019 |
[Clinical observation of cetylpyridinium chloride buccal tablets combined with Chinese patent medicine in the treatment of acute pharyngitis].
Topics: Cetylpyridinium; Humans; Nonprescription Drugs; Pharyngitis; Tablets | 2020 |
[Clinical observation on the treatment of acute simple pharyngitis with cetylpyridinium chloride buccal tablets].
Topics: Anti-Infective Agents, Local; Cetylpyridinium; Humans; Pharyngitis; Tablets | 2019 |
[Therapy of acute inflammatory diseases of the mouth and pharyngeal space].
Topics: Acute Disease; Adolescent; Adult; Aged; Ammonium Chloride; Anti-Inflammatory Agents; Cetylpyridinium | 1979 |
[Inflammatory diseases of the mouth and pharyngeal area. Possibilities of a conservative therapy].
Topics: Aconitum; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Atropine; Cetylpyridinium; Child; Child | 1973 |