Page last updated: 2024-10-24

cetylpyridinium and Grippe

cetylpyridinium has been researched along with Grippe in 4 studies

Cetylpyridinium: Cationic bactericidal surfactant used as a topical antiseptic for skin, wounds, mucous membranes, instruments, etc.; and also as a component in mouthwash and lozenges.

Research Excerpts

ExcerptRelevanceReference
"Prior influenza vaccination had no effect on study outcome."2.84Randomized, double-blind, placebo-controlled clinical trial to assess the safety and effectiveness of a novel dual-action oral topical formulation against upper respiratory infections. ( Adkins, I; Arters, K; Buchheit, K; Esper, F; Ghannoum, MA; Mukherjee, PK; Salata, RA, 2017)
"Reduction in density of influenza viral protein hemagglutinin (HA) clusters is known to reduce influenza infectivity: here, we show that CPC (at non-cytotoxic doses, 5-10 μM) reduces HA density and number of HA molecules per cluster within the plasma membrane of NIH-3T3 mouse fibroblasts."1.72Cetylpyridinium chloride (CPC) reduces zebrafish mortality from influenza infection: Super-resolution microscopy reveals CPC interference with multiple protein interactions with phosphatidylinositol 4,5-bisphosphate in immune function. ( Burnell, JE; Gosse, JA; Hess, ST; King, BL; Kinney, MS; Obeng, B; Potts, CM; Raut, P; Sangroula, S; Soos, BL; Weller, SR; West, BE, 2022)
"Whether the absence rate due to common cold and influenza changed by encouraging the use of the PVP-I gargle was determined by comparing a middle school where the PVP-I gargle was used and other middle schools where it was not."1.31Evaluation of the bactericidal activity of povidone-iodine and commercially available gargle preparations. ( Nakagawa, Y; Shiraishi, T, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Raut, P1
Weller, SR1
Obeng, B1
Soos, BL1
West, BE1
Potts, CM1
Sangroula, S1
Kinney, MS1
Burnell, JE1
King, BL1
Gosse, JA1
Hess, ST1
Mukherjee, PK1
Esper, F1
Buchheit, K1
Arters, K1
Adkins, I1
Ghannoum, MA1
Salata, RA1
Shiraishi, T1
Nakagawa, Y1
Mahlberg, FA1
Rodermund, OE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of the Safety, Tolerability, and Effectiveness of Halo to Prevent Acute Upper Respiratory Disease and Respiratory Virus Infections[NCT02644135]100 participants (Actual)Interventional2013-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Acute Respiratory Illnesses

Measured by medical record review. (NCT02644135)
Timeframe: Through study duration, an average of 3 months

InterventionNumber of acute respiratory illnesses (Number)
Halo Oral Spray4
Halo Placebo2

Number of Participants That Develop Acute Respiratory Illnesses When Using Halo vs Placebo

(NCT02644135)
Timeframe: Through study duration, an average of 3 months

Interventionparticipants (Number)
Halo Oral Spray2
Halo Placebo4

Trials

1 trial available for cetylpyridinium and Grippe

ArticleYear
Randomized, double-blind, placebo-controlled clinical trial to assess the safety and effectiveness of a novel dual-action oral topical formulation against upper respiratory infections.
    BMC infectious diseases, 2017, 01-14, Volume: 17, Issue:1

    Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Anti-Infective Agents, Local; Cety

2017

Other Studies

3 other studies available for cetylpyridinium and Grippe

ArticleYear
Cetylpyridinium chloride (CPC) reduces zebrafish mortality from influenza infection: Super-resolution microscopy reveals CPC interference with multiple protein interactions with phosphatidylinositol 4,5-bisphosphate in immune function.
    Toxicology and applied pharmacology, 2022, 04-01, Volume: 440

    Topics: Animals; Cell Communication; Cetylpyridinium; COVID-19; Humans; Immunity; Influenza, Human; Mammals;

2022
Evaluation of the bactericidal activity of povidone-iodine and commercially available gargle preparations.
    Dermatology (Basel, Switzerland), 2002, Volume: 204 Suppl 1

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Cetylpyridinium; Common Cold; Humans; Influenza, Hu

2002
[Periorbital purpura in influenza infection after cetylpyridium chloride?].
    Zeitschrift fur Hautkrankheiten, 1976, Nov-01, Volume: 51, Issue:21

    Topics: Adolescent; Cetylpyridinium; Drug Eruptions; Drug Hypersensitivity; Humans; Influenza, Human; Male;

1976