Page last updated: 2024-10-24

cetylpyridinium and Gingivitis

cetylpyridinium has been researched along with Gingivitis in 63 studies

Cetylpyridinium: Cationic bactericidal surfactant used as a topical antiseptic for skin, wounds, mucous membranes, instruments, etc.; and also as a component in mouthwash and lozenges.

Gingivitis: Inflammation of gum tissue (GINGIVA) without loss of connective tissue.

Research Excerpts

ExcerptRelevanceReference
"12% chlorhexidine gluconate (CHX) mouthwash and a placebo in reducing plaque accumulation and gingival inflammation."9.69Efficacy of 0.05% cetylpyridinium chloride mouthwash as an adjunct to toothbrushing compared with 0.12% chlorhexidine gluconate mouthwash in reducing dental plaque and gingival inflammation: A randomized control trial. ( Oo, MMT; Oo, PH; Saddki, N, 2023)
"05% cetylpyridinium chloride (CPC) mouth rinse, as an adjunct to professional plaque removal (PPR) and mechanical hygiene, in the treatment of peri-implant mucositis (PiM) and gingivitis."9.41Efficacy of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in reducing inflammation around the teeth and implants: a randomized clinical trial. ( Alonso, B; Bollain, J; Figuero, E; Herrera, D; Pulcini, A; Sanz, M; Sanz-Sánchez, I, 2021)
"The authors of this study aimed to evaluate the clinical antiplaque and antigingivitis effects of 3 oral hygiene regimens: toothbrushing with standard fluoride toothpaste and manual toothbrush and using a mouthrinse containing cetylpyridinium chloride, zinc lactate, and fluoride (CPC + Zn + F) in an alcohol-free base; toothbrushing with standard fluoride toothpaste and manual toothbrush and using a mouthrinse containing essential oils (EO) in an alcohol-free base; and toothbrushing with manual toothbrush and standard fluoride toothpaste and manual toothbrush (control)."9.41Antiplaque and antigingivitis efficacy of cetylpyridinium chloride with zinc lactate compared with essential oil mouthrinses: Randomized clinical trial. ( Cavagni, J; Friedrich, SA; Kilpatrick, L; Langa, GPJ; Malheiros, Z; Muniz, FWMG; Nicolini, AC; Oballe, HJR; Rösing, CK; Rup, AG; Ryan, M; Sossai, LL; Stewart, B; Thomé, DP, 2021)
"the aim of this study was to evaluate the effects of the use of a mouth rinse and dentifrice with cetylpyridinium chloride (CPC) in patients with gingivitis."9.16Clinical and microbiological efficacy of an antimicrobial mouth rinse containing 0.05% cetylpyridinium chloride in patients with gingivitis. ( García, V; Herrera, D; O'Connor, A; Rioboo, M; Sanz, M; Serrano, J, 2012)
"05% cetylpyridinium chloride (CPC) for controlling established dental plaque and gingivitis relative to that of a control mouthrinse without CPC."9.14A clinical investigation of the efficacy of a commercial mouthrinse containing 0.05% cetylpyridinium chloride to control established dental plaque and gingivitis. ( DeVizio, W; dos Santos, NB; Proskin, HM; Silva, MF; Stewart, B, 2009)
"07% cetylpyridinium chloride (CPC) (Crest Pro-Health) with those provided by a commercially available mouth rinse containing essential oils (EOs) (Listerine) on dental plaque accumulation and prevention of gingivitis in an unsupervised 6-month randomized clinical trial."9.12Comparison of the effects of cetylpyridinium chloride with an essential oil mouth rinse on dental plaque and gingivitis - a six-month randomized controlled clinical trial. ( Albert-Kiszely, A; Hamilton, A; Lang, NP; Persson, GR; Pjetursson, BE; Salvi, GE; Witt, J, 2007)
"07% high bioavailable cetylpyridinium chloride (Crest Pro-Health Rinse) on the development of gingivitis and plaque versus a placebo control over a period of 6 months."9.11A 6-month clinical trial to study the effects of a cetylpyridinium chloride mouthrinse on gingivitis and plaque. ( Bauroth, K; Bsoul, S; Dunavent, J; Gibb, R; Hamilton, A; He, T; Mankodi, S; Witt, JJ, 2005)
"1% cetylpyridinium chloride(CPC) rinse on the treatment of gingivitis and periodontitis."9.10[Analysis for clinical effect of a rinse containing cetylpyridinium chloride in treatment of gingivitis and periodontitis]. ( Cai, ZW; Chu, M; Guo, JZ; Hu, CZ; Jin, HL; Liang, JP; Lu, Z; Sheng, QP, 2003)
"05% cetylpyridinium chloride (CPC) for the control of supragingival dental plaque and gingivitis."9.08Efficacy of a mouthrinse containing 0.05% cetylpyridinium chloride for the control of plaque and gingivitis: a 6-month clinical study in adults. ( Allen, DR; Bradshaw, B; Chaknis, P; Davies, R; Ellwood, R; Mukerjee, C; Petrone, ME; Proskin, HM; Robinson, R; Simone, AJ; Volpe, AR, 1998)
"Home-use studies on dentine hypersensitivity have most commonly involved toothpastes and rarely have mouthrinses been employed."6.69The effects of a potassium citrate, cetylpyridinium chloride, sodium fluoride mouthrinse on dentine hypersensitivity, plaque and gingivitis. A placebo-controlled study. ( Addy, M; Marlow, I; West, N; Yates, R, 1998)
"12% chlorhexidine gluconate (CHX) mouthwash and a placebo in reducing plaque accumulation and gingival inflammation."5.69Efficacy of 0.05% cetylpyridinium chloride mouthwash as an adjunct to toothbrushing compared with 0.12% chlorhexidine gluconate mouthwash in reducing dental plaque and gingival inflammation: A randomized control trial. ( Oo, MMT; Oo, PH; Saddki, N, 2023)
"05% cetylpyridinium chloride (CPC) mouth rinse, as an adjunct to professional plaque removal (PPR) and mechanical hygiene, in the treatment of peri-implant mucositis (PiM) and gingivitis."5.41Efficacy of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in reducing inflammation around the teeth and implants: a randomized clinical trial. ( Alonso, B; Bollain, J; Figuero, E; Herrera, D; Pulcini, A; Sanz, M; Sanz-Sánchez, I, 2021)
"The authors of this study aimed to evaluate the clinical antiplaque and antigingivitis effects of 3 oral hygiene regimens: toothbrushing with standard fluoride toothpaste and manual toothbrush and using a mouthrinse containing cetylpyridinium chloride, zinc lactate, and fluoride (CPC + Zn + F) in an alcohol-free base; toothbrushing with standard fluoride toothpaste and manual toothbrush and using a mouthrinse containing essential oils (EO) in an alcohol-free base; and toothbrushing with manual toothbrush and standard fluoride toothpaste and manual toothbrush (control)."5.41Antiplaque and antigingivitis efficacy of cetylpyridinium chloride with zinc lactate compared with essential oil mouthrinses: Randomized clinical trial. ( Cavagni, J; Friedrich, SA; Kilpatrick, L; Langa, GPJ; Malheiros, Z; Muniz, FWMG; Nicolini, AC; Oballe, HJR; Rösing, CK; Rup, AG; Ryan, M; Sossai, LL; Stewart, B; Thomé, DP, 2021)
"To compare the effectiveness of a novel cetylpyridinium chloride (CPC)-hyaluronic acid (HA)-based mouthrinse with chlorhexidine (CHX) and placebo mouthrinses in preventing plaque and gingivitis."5.34Clinical efficacy of a new cetylpyridinium chloride-hyaluronic acid-based mouthrinse compared to chlorhexidine and placebo mouthrinses-A 21-day randomized clinical trial. ( Bharathwaj, VV; Duraiswamy, P; Sforza, C; Tadakamadla, SK; Tartaglia, GM, 2020)
"This study aimed to evaluate the anti-plaque and anti-gingivitis effects of two mouthwashes containing cetylpyridinium chloride (CPC), in comparison to negative control mouthwash."5.24Efficacy of two mouthwashes with cetylpyridinium chloride: a controlled randomized clinical trial. ( Cavagni, J; Friedrich, SA; Gaio, EJ; Muniz, FWMG; Oballe, HJR; Ranzan, N; Rösing, CK; Severo, RM; Stewart, B; Zhang, YP, 2017)
"07% cetylpyridinium chloride (CPC) in controlling established dental plaque and gingivitis compared to a non-antibacterial control mouthwash."5.20Efficacy of two fluoride-free, alcohol-free mouthwashes containing 0.075% or 0.07% CPC in controlling established dental plaque and gingivitis over a 6-week period on adults in Puerto Rico. ( Ahmed, R; Elias-Boneta, AR; Mateo, LR; Miller, JM; Morrison, BM; Pilch, S; Stewart, B; Toro, MJ, 2015)
"76% sodium monofluorophosphate toothpaste, a manual toothbrush and a fluoride-free and alcohol-free non-antibacterial mouthwash in the reduction and control of established plaque and gingivitis after 4 weeks of product use."5.20Randomized clinical trial of two oral care regimens in reducing and controlling established dental plaque and gingivitis. ( Ayad, F; Dillon, R; Mateo, LR; Miller, JM; Pilch, S; Stewart, B, 2015)
"the aim of this study was to evaluate the effects of the use of a mouth rinse and dentifrice with cetylpyridinium chloride (CPC) in patients with gingivitis."5.16Clinical and microbiological efficacy of an antimicrobial mouth rinse containing 0.05% cetylpyridinium chloride in patients with gingivitis. ( García, V; Herrera, D; O'Connor, A; Rioboo, M; Sanz, M; Serrano, J, 2012)
"05% cetylpyridinium chloride gel-releasing interdental brush (IDB) with standard interproximal cleaning devices for plaque and gingivitis reduction, and decreased frequency in interproximal gingival bleeding."5.11Clinical trial of a novel interdental brush cleaning system. ( Ebisutani, K; Jared, H; Rowe, M; Takase, N; Tanaka, T; Zhong, Y, 2005)
"07% high bioavailable cetylpyridinium chloride (Crest Pro-Health Rinse) on the development of gingivitis and plaque versus a placebo control over a period of 6 months."5.11A 6-month clinical trial to study the effects of a cetylpyridinium chloride mouthrinse on gingivitis and plaque. ( Bauroth, K; Bsoul, S; Dunavent, J; Gibb, R; Hamilton, A; He, T; Mankodi, S; Witt, JJ, 2005)
"1% cetylpyridinium chloride(CPC) rinse on the treatment of gingivitis and periodontitis."5.10[Analysis for clinical effect of a rinse containing cetylpyridinium chloride in treatment of gingivitis and periodontitis]. ( Cai, ZW; Chu, M; Guo, JZ; Hu, CZ; Jin, HL; Liang, JP; Lu, Z; Sheng, QP, 2003)
"6 mg cetylpyridinium chloride (MOTS [Mucosal Oral Therapeutic System] CPC) to inhibit new plaque formation and gingivitis, a single-blind, randomised, parallel group pilot study was set up."5.08Efficacy on supragingival plaque control of cetylpyridinium chloride in a slow-release dosage form. ( Encarnacion, M; Rosenberg, D; Tricio, J; Van Steenberghe, D; Vandekerckhove, BN, 1995)
"05% cetylpyridinium chloride (CPC) for the control of supragingival dental plaque and gingivitis."5.08Efficacy of a mouthrinse containing 0.05% cetylpyridinium chloride for the control of plaque and gingivitis: a 6-month clinical study in adults. ( Allen, DR; Bradshaw, B; Chaknis, P; Davies, R; Ellwood, R; Mukerjee, C; Petrone, ME; Proskin, HM; Robinson, R; Simone, AJ; Volpe, AR, 1998)
"The effect of a degradable controlled release system containing cetylpyridinium chloride (CPC) on plaque accumulation and gingivitis was evaluated when applied on the anterior teeth of volunteers (16-17 years) over 4 weeks."5.07Inhibition of plaque formation by local application of a degradable controlled release system containing cetylpyridinium chloride. ( Kozlovsky, A; Moldovan, M; Sintov, A; Tal, H, 1994)
"Mechanical interdental plaque control using interdental brushes combined with the use of CPC gel significantly improved 6-month gingival and periodontal outcomes (SBI and PD) compared with mechanical cleaning with interdental brushes alone."2.80Comparison Between Two Interproximal Cleaning Procedures in Periodontitis Patients: A Six-month, Single-blind, Randomised Controlled Clinical Trial. ( Jentsch, H; Schmidt, B, 2015)
"Gingivitis was measured on days -14 (baseline), 0 (after hygiene phase), and 21 (after no-hygiene phase) by using the Papillary Bleeding Score (PBS) and by standard digital imaging of the gum tissues (G-parameter)."2.79The effectiveness of propolis on gingivitis: a randomized controlled trial. ( Bretz, WA; Moreira, A; Nör, JE; Paulino, N, 2014)
"Gingivitis is a chronic inflammatory condition, resulting from gingival bacteria and bacterial byproducts."2.77Effect of an herbal mouth rinse in preventing periodontal inflammation in an experimental gingivitis model: a pilot study. ( Grbic, JT; Saffer, AJ; Samuels, N; Wexler, ID; Williams, RC, 2012)
"Levels of gingivitis, dental plaque, supragingival calculus, and dental staining were assessed at baseline and end (day 21) of experimental phases."2.71Influence of additional active ingredients on the effectiveness of non-alcoholic chlorhexidine mouthwashes: a randomized controlled trial. ( Bascones, A; Mata, M; Mateos, L; Morante, S; Poblet, J, 2005)
" The balance of intra-oral bacterial flora is not disturbed even in the case of relatively long-term use of CPC (up to six weeks)."2.70Efficacy of cetylpyridinium chloride used as oropharyngeal antiseptic. ( Kramer, A; Pitten, FA, 2001)
"Home-use studies on dentine hypersensitivity have most commonly involved toothpastes and rarely have mouthrinses been employed."2.69The effects of a potassium citrate, cetylpyridinium chloride, sodium fluoride mouthrinse on dentine hypersensitivity, plaque and gingivitis. A placebo-controlled study. ( Addy, M; Marlow, I; West, N; Yates, R, 1998)
"Periodontal diseases are a group of related inflammatory disorders, initiated by dental plaque and causing destruction of the supporting structures of the teeth."2.39Mouthrinses as adjuncts in periodontal therapy. ( Walsh, TF, 1996)

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19908 (12.70)18.7374
1990's8 (12.70)18.2507
2000's18 (28.57)29.6817
2010's23 (36.51)24.3611
2020's6 (9.52)2.80

Authors

AuthorsStudies
Langa, GPJ3
Dantas, PPA1
Lemus, GMR1
Benítez Silva, CG1
Meza-Mauricio, J1
Muniz, FWMG4
Oo, MMT1
Oo, PH1
Saddki, N1
Bollain, J1
Pulcini, A1
Sanz-Sánchez, I1
Figuero, E1
Alonso, B3
Sanz, M6
Herrera, D6
Costa, RDSA1
da Silveira, TM1
Rösing, CK3
Cavagni, J2
Oballe, HJR2
Friedrich, SA2
Nicolini, AC1
Thomé, DP1
Sossai, LL1
Rup, AG1
Malheiros, Z1
Stewart, B7
Kilpatrick, L1
Ryan, M1
Gaio, EJ1
Ranzan, N1
Severo, RM1
Zhang, YP1
Escudero, N1
Pérez, L1
Otheo, M1
Cañete-Sánchez, E1
Pérez, T1
Serrano, J4
Palma, JC1
Martín, C1
Tadakamadla, SK1
Bharathwaj, VV1
Duraiswamy, P1
Sforza, C1
Tartaglia, GM1
Costa, X1
Laguna, E1
Geisinger, ML1
Geurs, NC1
Bain, JL1
Kaur, M1
Vassilopoulos, PJ1
Cliver, SP1
Hauth, JC1
Reddy, MS1
Parikh-Das, AM1
Sharma, NC2
Du, Q1
Charles, CA2
Van Leeuwen, MP1
Rosema, NA1
Versteeg, PA1
Slot, DE2
Van Winkelhoff, AJ1
Van der Weijden, GA2
Schmidt, B1
Jentsch, H1
Cortelli, SC2
Cortelli, JR2
Shang, H1
Costa, R1
Bretz, WA1
Paulino, N1
Nör, JE1
Moreira, A1
Zimmer, S2
Korte, P1
Verde, P1
Ohmann, C1
Naumova, E1
Jordan, RA1
Cagetti, MG1
Strohmenger, L1
Basile, V1
Abati, S1
Mastroberardino, S1
Campus, G1
Elias-Boneta, AR2
Toro, MJ2
Mateo, LR4
Ahmed, R2
Morrison, BM2
Miller, JM3
Pilch, S3
Noboa, J1
Romeu, FL1
Chaknis, P2
Ayad, F2
Dillon, R1
Teng, F1
He, T2
Huang, S1
Bo, CP1
Li, Z1
Chang, JL1
Liu, JQ1
Charbonneau, D1
Xu, J1
Li, R1
Ling, JQ1
Lee, SS1
Aprecio, RM1
Zhang, W1
Arambula, M1
Wilkins, KB1
Stephens, JA1
Kim, JS1
Li, Y1
Haps, S1
Berchier, CE1
Silva, MF1
dos Santos, NB1
DeVizio, W1
Proskin, HM2
Escribano, M1
Morante, S2
Teughels, W1
Quirynen, M3
Araujo, MW1
Wu, MM1
Qaqish, J1
Charles, CH1
Aquino, DR1
Costa, FO1
Drake, D1
Villhauer, AL1
García, V2
Rioboo, M2
O'Connor, A2
Prado, R1
Szewczyk, G1
Arvanitidou, E1
Panagakos, FS1
Samuels, N1
Grbic, JT1
Saffer, AJ1
Wexler, ID1
Williams, RC1
Yates, R2
Shearer, BH1
Huntington, E1
Addy, M3
Hu, CZ1
Jin, HL1
Liang, JP1
Chu, M1
Guo, JZ1
Lu, Z1
Sheng, QP1
Cai, ZW1
Witt, J2
Ramji, N1
Gibb, R4
Dunavent, J3
Flood, J1
Barnes, J1
Jared, H1
Zhong, Y1
Rowe, M1
Ebisutani, K1
Tanaka, T1
Takase, N1
Bascones, A1
Mateos, L1
Mata, M1
Poblet, J1
Witt, JJ3
Walters, P1
Bsoul, S2
Putt, M1
Mankodi, S1
Bauroth, K1
Hamilton, A2
Stookey, GK1
Beiswanger, B1
Mau, M1
Isaacs, RL1
Paraskevas, S1
Kolbe, C1
Kaiser, G1
Krage, T1
Ommerborn, M1
Barthel, C1
Gunsolley, JC1
Albert-Kiszely, A1
Pjetursson, BE1
Salvi, GE1
Persson, GR1
Lang, NP1
Ashley, FP1
Skinner, A1
Jackson, P1
Woods, A1
Wilson, RF1
Gaffar, A1
Niles, HP1
Davis, CB1
Ritchey, TW1
Lamster, IB1
Mann, PH1
Alfano, MC1
Firatli, E1
Unal, T1
Onan, U1
Sandalli, P1
Simard, F1
Landry, RG1
Kozlovsky, A2
Sintov, A1
Moldovan, M1
Tal, H1
Vandekerckhove, BN1
Van Steenberghe, D3
Tricio, J1
Rosenberg, D1
Encarnacion, M1
Goldberg, S1
Natour, I1
Rogatky-Gat, A1
Gelernter, I1
Rosenberg, M1
Walsh, TF1
West, N1
Marlow, I1
Allen, DR1
Davies, R1
Bradshaw, B1
Ellwood, R1
Simone, AJ1
Robinson, R1
Mukerjee, C1
Petrone, ME1
Volpe, AR1
Pitten, FA1
Kramer, A1
Avontroodt, P2
Peeters, W2
Pauwels, M2
Coucke, W2
Lijnen, A1
Stricker, G1
Ravanelli, O1
Lobene, RR1
Kashket, S1
Soparkar, PM1
Shloss, J1
Sabine, ZM1
Rosa, M1
Sturzenberger, OP1
Moran, J1
Ciancio, SD1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical and Microbiological Effects of a 0.03% Chlorhexidine Mouth Rinse in the Prevention of Peri-implant Diseases: a Randomized Clinical Trial[NCT03533166]54 participants (Actual)Interventional2015-11-04Completed
Effectiveness of a Pre-procedural Mouthwash in Reducing Bacteria in Dental Aerosols and Splatters: a Randomized Clinical Trial[NCT02875769]Phase 360 participants (Actual)Interventional2015-02-28Completed
Efficacy of Three Antimicrobial Mouthwashes in Reducing SARS-CoV-2 Viral Load in the Saliva of Patients Diagnosed With COVID-19: A Pilot Study[NCT04723446]54 participants (Actual)Interventional2021-05-19Completed
Ozone Therapy as an Aid for Home Oral Hygiene. The Use of Aquolab in the Pregnant Woman.[NCT04140643]60 participants (Anticipated)Interventional2019-03-01Recruiting
Effect of a Liquid Toothpaste on Periodontal Disease : a Randomized, Double-blind, Placebo-controlled Study[NCT03117153]98 participants (Actual)Interventional2014-08-04Completed
Comparison Between Two Non-surgical Periodontal Treatment Procedures With and Without Interdental Hygiene Devices in Periodontitis Patients: a Longitudinal Prospective Controlled Clinical Trial[NCT04339309]52 participants (Actual)Interventional2015-04-30Completed
Mouth Rinses Efficacy on Salivary SARS-CoV-2 Viral Load: A Randomized Clinical Trial[NCT04721457]Phase 490 participants (Actual)Interventional2021-01-03Completed
"Effect of Single Rinsing With Three Different Types of Mouthwash on VSC Levels in Morning Breath; Randomized Clinical Trial, Double-blind Cross-sectional Study"[NCT04279106]36 participants (Actual)Interventional2018-09-03Completed
Comparing the Effect of 0,06 % -, 0,12 % and 0,2 % Chlorhexidine on Plaque, Bleeding and Side Effects in an Experimental Gingivitis Model. A Parallel, Double Masked, Randomized, Placebo-controlled Clinical Trial[NCT02911766]Phase 459 participants (Anticipated)Interventional2016-11-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for cetylpyridinium and Gingivitis

ArticleYear
Effectiveness of interdental cleaning devices with active substances: a systematic review.
    Clinical oral investigations, 2022, Volume: 26, Issue:3

    Topics: Cetylpyridinium; Dental Devices, Home Care; Dental Plaque; Gingivitis; Humans; Toothbrushing

2022
The effect of cetylpyridinium chloride mouthrinse as adjunct to toothbrushing compared to placebo on interproximal plaque and gingival inflammation-a systematic review with meta-analyses.
    Clinical oral investigations, 2021, Volume: 25, Issue:2

    Topics: Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque Index; Gingivitis; Humans; Inflammation

2021
The effect of cetylpyridinium chloride-containing mouth rinses as adjuncts to toothbrushing on plaque and parameters of gingival inflammation: a systematic review.
    International journal of dental hygiene, 2008, Volume: 6, Issue:4

    Topics: Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Dental Plaque Index; Gingivitis; Human

2008
Randomized controlled clinical trials on agents used for chemical plaque control.
    International journal of dental hygiene, 2005, Volume: 3, Issue:4

    Topics: Alkaloids; Anti-Infective Agents, Local; Benzophenanthridines; Cetylpyridinium; Chlorhexidine; Denta

2005
A meta-analysis of six-month studies of antiplaque and antigingivitis agents.
    Journal of the American Dental Association (1939), 2006, Volume: 137, Issue:12

    Topics: Anti-Infective Agents, Local; Cetylpyridinium; Chlorhexidine; Dental Plaque; Dentifrices; Drug Combi

2006
Mouthrinses as an antibacterial adjunct in periodontal treatment.
    Journal (Canadian Dental Association), 1994, Volume: 60, Issue:10

    Topics: Alkaloids; Benzoates; Benzophenanthridines; Benzydamine; Cetylpyridinium; Chlorhexidine; Dental Plaq

1994
Mouthrinses as adjuncts in periodontal therapy.
    Dental update, 1996, Volume: 23, Issue:4

    Topics: Adult; Anti-Infective Agents, Local; Cetylpyridinium; Child; Child, Preschool; Chlorhexidine; Chlori

1996

Trials

48 trials available for cetylpyridinium and Gingivitis

ArticleYear
Efficacy of 0.05% cetylpyridinium chloride mouthwash as an adjunct to toothbrushing compared with 0.12% chlorhexidine gluconate mouthwash in reducing dental plaque and gingival inflammation: A randomized control trial.
    International journal of dental hygiene, 2023, Volume: 21, Issue:1

    Topics: Anti-Infective Agents, Local; Cetylpyridinium; Chlorhexidine; Dental Plaque; Dental Plaque Index; Do

2023
Efficacy of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in reducing inflammation around the teeth and implants: a randomized clinical trial.
    Clinical oral investigations, 2021, Volume: 25, Issue:4

    Topics: Anti-Infective Agents, Local; Cetylpyridinium; Chlorhexidine; Dental Implants; Dental Plaque; Dental

2021
Antiplaque and antigingivitis efficacy of cetylpyridinium chloride with zinc lactate compared with essential oil mouthrinses: Randomized clinical trial.
    Journal of the American Dental Association (1939), 2021, Volume: 152, Issue:2

    Topics: Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Dental Plaque Index; Gingivitis; Human

2021
Efficacy of two mouthwashes with cetylpyridinium chloride: a controlled randomized clinical trial.
    Brazilian oral research, 2017, Jul-03, Volume: 31

    Topics: Adult; Aged; Analysis of Variance; Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Den

2017
Clinical and microbiological effects of the use of a cetylpyridinium chloride dentifrice and mouth rinse in orthodontic patients: a 3-month randomized clinical trial.
    European journal of orthodontics, 2018, 09-28, Volume: 40, Issue:5

    Topics: Adolescent; Anti-Infective Agents, Local; Cetylpyridinium; Child; Dental Plaque; Dental Plaque Index

2018
Clinical efficacy of a new cetylpyridinium chloride-hyaluronic acid-based mouthrinse compared to chlorhexidine and placebo mouthrinses-A 21-day randomized clinical trial.
    International journal of dental hygiene, 2020, Volume: 18, Issue:1

    Topics: Anti-Infective Agents, Local; Cetylpyridinium; Chlorhexidine; Dental Plaque Index; Double-Blind Meth

2020
Efficacy of a new mouth rinse formulation based on 0.07% cetylpyridinium chloride in the control of plaque and gingivitis: a 6-month randomized clinical trial.
    Journal of clinical periodontology, 2013, Volume: 40, Issue:11

    Topics: Adult; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents, Local; Bacteroides; Capnocytoph

2013
Efficacy of a new mouth rinse formulation based on 0.07% cetylpyridinium chloride in the control of plaque and gingivitis: a 6-month randomized clinical trial.
    Journal of clinical periodontology, 2013, Volume: 40, Issue:11

    Topics: Adult; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents, Local; Bacteroides; Capnocytoph

2013
Efficacy of a new mouth rinse formulation based on 0.07% cetylpyridinium chloride in the control of plaque and gingivitis: a 6-month randomized clinical trial.
    Journal of clinical periodontology, 2013, Volume: 40, Issue:11

    Topics: Adult; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents, Local; Bacteroides; Capnocytoph

2013
Efficacy of a new mouth rinse formulation based on 0.07% cetylpyridinium chloride in the control of plaque and gingivitis: a 6-month randomized clinical trial.
    Journal of clinical periodontology, 2013, Volume: 40, Issue:11

    Topics: Adult; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents, Local; Bacteroides; Capnocytoph

2013
Oral health education and therapy reduces gingivitis during pregnancy.
    Journal of clinical periodontology, 2014, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Cariostatic Agents; Cetylpyridinium; Counseling; De

2014
Superiority of essential oils versus 0.075% CPC-containing mouthrinse: a two-week randomized clinical trial.
    The Journal of clinical dentistry, 2013, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Infective Agents, Local; Cetylpyridinium; Cycloh

2013
Long-term efficacy of a 0.07% cetylpyridinium chloride mouth rinse in relation to plaque and gingivitis: a 6-month randomized, vehicle-controlled clinical trial.
    International journal of dental hygiene, 2015, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial L

2015
Comparison Between Two Interproximal Cleaning Procedures in Periodontitis Patients: A Six-month, Single-blind, Randomised Controlled Clinical Trial.
    Oral health & preventive dentistry, 2015, Volume: 13, Issue:3

    Topics: Adult; Aged; Anti-Infective Agents, Local; Cetylpyridinium; Chronic Periodontitis; Combined Modality

2015
Gingival health benefits of essential-oil and cetylpyridinium chloride mouthrinses: a 6-month randomized clinical study.
    American journal of dentistry, 2014, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Dental Plaque

2014
The effectiveness of propolis on gingivitis: a randomized controlled trial.
    Journal of alternative and complementary medicine (New York, N.Y.), 2014, Volume: 20, Issue:12

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Apitherapy; Cetylpyridinium; Double-Blind Method; F

2014
Randomized controlled trial on the efficacy of new alcohol-free chlorhexidine mouthrinses after 8 weeks.
    International journal of dental hygiene, 2015, Volume: 13, Issue:2

    Topics: Adult; Anti-Infective Agents, Local; Cariostatic Agents; Cetylpyridinium; Chlorhexidine; Dental Plaq

2015
Effect of a toothpaste containing triclosan, cetylpyridinium chloride, and essential oils on gingival status in schoolchildren: a randomized clinical pilot study.
    Quintessence international (Berlin, Germany : 1985), 2015, Volume: 46, Issue:5

    Topics: Anti-Infective Agents, Local; Cetylpyridinium; Child; Dental Plaque Index; Double-Blind Method; Fluo

2015
Efficacy of two fluoride-free, alcohol-free mouthwashes containing 0.075% or 0.07% CPC in controlling established dental plaque and gingivitis over a 6-week period on adults in Puerto Rico.
    American journal of dentistry, 2015, Volume: 28 Spec No A

    Topics: Adult; Alcohols; Cetylpyridinium; Dental Plaque; Double-Blind Method; Female; Fluorides; Gingivitis;

2015
Efficacy of CPC and essential oils mouthwashes compared to a negative control mouthwash in controlling established dental plaque and gingivitis: A 6-week, randomized clinical trial.
    American journal of dentistry, 2015, Volume: 28 Spec No A

    Topics: Cetylpyridinium; Dental Plaque; Double-Blind Method; Gingivitis; Humans; Mouthwashes; Oils, Volatile

2015
Randomized clinical trial of two oral care regimens in reducing and controlling established dental plaque and gingivitis.
    American journal of dentistry, 2015, Volume: 28 Spec No A

    Topics: Adolescent; Adult; Aged; Cetylpyridinium; Dental Plaque; Double-Blind Method; Fluorides; Gingivitis;

2015
Cetylpyridinium chloride mouth rinses alleviate experimental gingivitis by inhibiting dental plaque maturation.
    International journal of oral science, 2016, 09-29, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Dental Plaque Index

2016
Antiplaque/antigingivitis efficacy and safety of a cetylpyridinium chloride/zinc gluconate mucoadhesive gel. Results of a 6-month clinical trial.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2008, Volume: 29, Issue:5

    Topics: Adult; Aged; Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Dental Plaque Index; Fema

2008
A clinical investigation of the efficacy of a commercial mouthrinse containing 0.05% cetylpyridinium chloride to control established dental plaque and gingivitis.
    The Journal of clinical dentistry, 2009, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Dental Plaque Index

2009
Efficacy of a low-concentration chlorhexidine mouth rinse in non-compliant periodontitis patients attending a supportive periodontal care programme: a randomized clinical trial.
    Journal of clinical periodontology, 2010, Volume: 37, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Anti-Infective Agents, Local; Cetylpyridinium; Chi-Square Distrib

2010
Superiority of an essential oil mouthrinse when compared with a 0.05% cetylpyridinium chloride containing mouthrinse: a six-month study.
    International dental journal, 2010, Volume: 60, Issue:3

    Topics: Adult; Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Dental Plaque Index; Dental Pro

2010
Plaque inhibitory effect of a 0.05% cetyl-pyridinium chloride mouth-rinse in a 4-day non-brushing model.
    International journal of dental hygiene, 2011, Volume: 9, Issue:4

    Topics: Adult; Analysis of Variance; Bacteria, Anaerobic; Cetylpyridinium; Colony Count, Microbial; Cross-Ov

2011
Clinical and microbiological efficacy of an antimicrobial mouth rinse containing 0.05% cetylpyridinium chloride in patients with gingivitis.
    International journal of dental hygiene, 2012, Volume: 10, Issue:2

    Topics: Adult; Anti-Infective Agents, Local; Bacteria; Cetylpyridinium; Colony Count, Microbial; Combined Mo

2012
A comparative investigation to evaluate the clinical efficacy of an alcohol-free CPC-containing mouthwash as compared to a control mouthwash in controlling dental plaque and gingivitis: a six-month clinical study on adults in San Jose, Costa Rica.
    The Journal of clinical dentistry, 2011, Volume: 22, Issue:6

    Topics: Adult; Anti-Infective Agents, Local; Cetylpyridinium; Costa Rica; Dental Plaque; Dental Plaque Index

2011
Effect of an herbal mouth rinse in preventing periodontal inflammation in an experimental gingivitis model: a pilot study.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2012, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Centella; Cetylpyridinium

2012
A method to compare four mouthrinses: time to gingivitis level as the primary outcome variable.
    Journal of clinical periodontology, 2002, Volume: 29, Issue:6

    Topics: Adult; Analysis of Variance; Anti-Infective Agents, Local; Cariostatic Agents; Cetylpyridinium; Chlo

2002
[Analysis for clinical effect of a rinse containing cetylpyridinium chloride in treatment of gingivitis and periodontitis].
    Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2003, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Aged; Cetylpyridinium; Dental Plaque; Female; Gingivitis; Humans; Male; Middle Ag

2003
Antibacterial and antiplaque effects of a novel, alcohol-free oral rinse with cetylpyridinium chloride.
    The journal of contemporary dental practice, 2005, Feb-15, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Alcohols; Anti-Infective Agents, Local; Bacteria, Anaerobic; Cetylpyridinium; Col

2005
Clinical trial of a novel interdental brush cleaning system.
    The Journal of clinical dentistry, 2005, Volume: 16, Issue:2

    Topics: Adult; Anti-Infective Agents, Local; Biofilms; Cetylpyridinium; Dental Devices, Home Care; Dental Pl

2005
Influence of additional active ingredients on the effectiveness of non-alcoholic chlorhexidine mouthwashes: a randomized controlled trial.
    Journal of periodontology, 2005, Volume: 76, Issue:9

    Topics: Adult; Anti-Infective Agents, Local; Cetylpyridinium; Chi-Square Distribution; Chlorhexidine; Cross-

2005
Comparative clinical trial of two antigingivitis mouthrinses.
    American journal of dentistry, 2005, Volume: 18 Spec No

    Topics: Adult; Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Dental Plaque Index; Double-Bli

2005
A 6-month clinical trial to study the effects of a cetylpyridinium chloride mouthrinse on gingivitis and plaque.
    American journal of dentistry, 2005, Volume: 18 Spec No

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Dental Plaque

2005
A 6-month clinical study assessing the safety and efficacy of two cetylpyridinium chloride mouthrinses.
    American journal of dentistry, 2005, Volume: 18 Spec No

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Cetylpyridinium; Chlorhexidine; Dental Plaque

2005
Clinical efficacy of flossing versus use of antimicrobial rinses.
    Journal of periodontology, 2006, Volume: 77, Issue:8

    Topics: Adult; Analysis of Variance; Anti-Infective Agents, Local; Cetylpyridinium; Chlorhexidine; Dental De

2006
Comparison of the effects of cetylpyridinium chloride with an essential oil mouth rinse on dental plaque and gingivitis - a six-month randomized controlled clinical trial.
    Journal of clinical periodontology, 2007, Volume: 34, Issue:8

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Epidemiologic Metho

2007
Inhibition of plaque formation by local application of a degradable controlled release system containing cetylpyridinium chloride.
    Journal of clinical periodontology, 1994, Volume: 21, Issue:1

    Topics: Administration, Topical; Adolescent; Cetylpyridinium; Delayed-Action Preparations; Dental Plaque; Do

1994
Efficacy on supragingival plaque control of cetylpyridinium chloride in a slow-release dosage form.
    Journal of clinical periodontology, 1995, Volume: 22, Issue:11

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Cetylpyridinium; Chlorhexidine; Delayed-Action Prep

1995
Efficacy of a 2-phase oil: water mouthrinse in controlling oral malodor, gingivitis, and plaque.
    Journal of periodontology, 1996, Volume: 67, Issue:6

    Topics: Adult; Analysis of Variance; Breath Tests; Cadaverine; Cetylpyridinium; Dental Plaque; Dental Plaque

1996
The effects of a potassium citrate, cetylpyridinium chloride, sodium fluoride mouthrinse on dentine hypersensitivity, plaque and gingivitis. A placebo-controlled study.
    Journal of clinical periodontology, 1998, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Cetylpyridinium; Chi-Square Distribution; Den

1998
Efficacy of a mouthrinse containing 0.05% cetylpyridinium chloride for the control of plaque and gingivitis: a 6-month clinical study in adults.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 1998, Volume: 19, Issue:2 Suppl

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Cetylpyridinium; Dental Plaque; Dental Plaque

1998
Efficacy of cetylpyridinium chloride used as oropharyngeal antiseptic.
    Arzneimittel-Forschung, 2001, Volume: 51, Issue:7

    Topics: Anti-Infective Agents, Local; Bacteremia; Biofilms; Cetylpyridinium; Dental Plaque; Gingivitis; Gram

2001
Efficacy of cetylpyridinium chloride used as oropharyngeal antiseptic.
    Arzneimittel-Forschung, 2001, Volume: 51, Issue:7

    Topics: Anti-Infective Agents, Local; Bacteremia; Biofilms; Cetylpyridinium; Dental Plaque; Gingivitis; Gram

2001
Efficacy of cetylpyridinium chloride used as oropharyngeal antiseptic.
    Arzneimittel-Forschung, 2001, Volume: 51, Issue:7

    Topics: Anti-Infective Agents, Local; Bacteremia; Biofilms; Cetylpyridinium; Dental Plaque; Gingivitis; Gram

2001
Efficacy of cetylpyridinium chloride used as oropharyngeal antiseptic.
    Arzneimittel-Forschung, 2001, Volume: 51, Issue:7

    Topics: Anti-Infective Agents, Local; Bacteremia; Biofilms; Cetylpyridinium; Dental Plaque; Gingivitis; Gram

2001
Effect of different mouthrinses on morning breath.
    Journal of periodontology, 2001, Volume: 72, Issue:9

    Topics: Adult; Anti-Infective Agents, Local; Bacteria, Anaerobic; Breath Tests; Cetylpyridinium; Chlorhexidi

2001
Effect of different chlorhexidine formulations in mouthrinses on de novo plaque formation.
    Journal of clinical periodontology, 2001, Volume: 28, Issue:12

    Topics: Adult; Anti-Infective Agents, Local; Bacteria; Cetylpyridinium; Chlorhexidine; Colony Count, Microbi

2001
[Treatment of inflammatory diseases in the mouth and pharynx using Imposit].
    Therapie der Gegenwart, 1975, Volume: 114, Issue:1

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aminobenzoates; Anti-Inflammatory Agents; Benzyl C

1975
Clinical reduction of gingivitis through the use of a mouthwash containing two quaternary ammonium compounds.
    Journal of periodontology, 1976, Volume: 47, Issue:9

    Topics: Adolescent; Adult; Cetylpyridinium; Child; Female; Gingivitis; Humans; Male; Mouthwashes; Phenyl Eth

1976
The effect of a cetylpyridinium chloride (CPC) detergent foam compared to a conventional toothpaste on plaque and gingivitis. A single blind crossover study.
    Journal of clinical periodontology, 1989, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Cetylpyridinium; Dental Plaque; Dental Plaque Index; Dentifrices; Female; Fluorid

1989

Other Studies

8 other studies available for cetylpyridinium and Gingivitis

ArticleYear
Self-performed supragingival biofilm control: qualitative analysis, scientific basis and oral-health implications.
    Brazilian oral research, 2010, Volume: 24 Suppl 1

    Topics: Anti-Infective Agents; Biofilms; Cetylpyridinium; Chlorhexidine; Dental Plaque; Gingivitis; Health K

2010
An in vitro comparative study determining bactericidal activity of stabilized chlorine dioxide and other oral rinses.
    The Journal of clinical dentistry, 2011, Volume: 22, Issue:1

    Topics: Actinomyces; Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Anti-Infective Agents, Lo

2011
The effect of a 0.1% cetylpyridinium chloride mouthrinse on plaque and gingivitis in adult subjects.
    British dental journal, 1984, Sep-22, Volume: 157, Issue:6

    Topics: Adult; Cetylpyridinium; Dental Plaque; Dental Plaque Index; Drug Evaluation; Gingivitis; Humans; Mid

1984
Evaluation of an oligomer or an oligomer plus cetyl pyridinium chloride against plaque, stain, calculus, and gingivitis.
    Journal of dental research, 1981, Volume: 60, Issue:8

    Topics: Acrylic Resins; Animals; Cetylpyridinium; Dental Calculus; Dental Enamel; Dental Plaque; Dogs; Femal

1981
The effect of zinc chloride on the development of gingivitis in beagle dogs treated with cetylpyridinium chloride.
    Journal of dental research, 1982, Volume: 61, Issue:10

    Topics: Animals; Cetylpyridinium; Chlorides; Dental Plaque; Dental Plaque Index; Dogs; Drug Combinations; Gi

1982
Antioxidative activities of some chemotherapeutics. A possible mechanism in reducing gingival inflammation.
    Journal of clinical periodontology, 1994, Volume: 21, Issue:10

    Topics: Alkaloids; Animals; Anti-Infective Agents, Local; Antioxidants; Benzophenanthridines; Brain; Cattle;

1994
The effect of cetylpridinium chloride on human plaque bacteria and gingivitis.
    Pharmacology and therapeutics in dentistry, 1979, Volume: 4, Issue:1

    Topics: Bacteria; Cetylpyridinium; Dental Plaque; Gingivitis; Mouthwashes; Pyridinium Compounds

1979
Chemotherapeutic agents in general practice: two views.
    Journal of the American Dental Association (1939), 1986, Volume: 112, Issue:1

    Topics: Cetylpyridinium; Dental Plaque; General Practice, Dental; Gingivitis; Humans; Oral Hygiene; Phenols

1986