cetraxate has been researched along with Stomach Ulcer in 20 studies
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We introduced a double-blind controlled clinical study to compare intravenous human epidermal growth factor (hEGF) to cetraxate hydrochloride (CH), an antiulcer drug, for their healing effect on gastric ulcers." | 9.07 | Gastric ulcer treatment with intravenous human epidermal growth factor: a double-blind controlled clinical study. ( Itoh, M; Matsuo, Y, 1994) |
| "Forty-nine Chinese patients, ages 65 years or over, with endoscopically and pathologically diagnosed benign gastric ulcer, completed a randomized double-blind double dummy trial in treatment with either cetraxate 200 mg four times daily or ranitidine 150 mg two times daily for 12 weeks or less if the gastric ulcer had completely healed." | 9.06 | Healing of gastric ulcer in the elderly: a double-blind study of cetraxate versus ranitidine. ( Lee, YC; Ng, NS; Tam, HC; Wong, HY, 1989) |
| "We investigated the effect of the anti-ulcer drug cetraxate on the development of the gastric ulcer induced by the submucosal injection of endothelin-1 in the rat gastric body, and its effects on gastric mucosal hemodynamics and tissue oxygenation by Laser doppler flowmetry and tissue spectrophotometry." | 7.68 | Endothelin-1-induced gastric ulcer is attenuated by cetraxate. ( Fukutomi, H; Goto, K; Kashimura, H; Lazaratos, S; Miyauchi, T; Nakahara, A; Osuga, T, 1993) |
| " pylori) infection is known to affect the gastric microcirculation, and cetraxate is reported to accelerate gastric ulcer healing, possibly by augmenting gastric mucosal blood flow (MBF)." | 5.09 | Influence of Helicobacter pylori infection and cetraxate on gastric mucosal blood flow during healing of endoscopic mucosal resection-induced ulcers. ( Adachi, K; Fujishiro, H; Ishihara, S; Kawamura, A; Kazumori, H; Kinoshita, Y; Moriyama, N; Okuyama, T; Sato, H; Suetsugu, H; Watanabe, M, 2001) |
| "We introduced a double-blind controlled clinical study to compare intravenous human epidermal growth factor (hEGF) to cetraxate hydrochloride (CH), an antiulcer drug, for their healing effect on gastric ulcers." | 5.07 | Gastric ulcer treatment with intravenous human epidermal growth factor: a double-blind controlled clinical study. ( Itoh, M; Matsuo, Y, 1994) |
| "Forty-nine Chinese patients, ages 65 years or over, with endoscopically and pathologically diagnosed benign gastric ulcer, completed a randomized double-blind double dummy trial in treatment with either cetraxate 200 mg four times daily or ranitidine 150 mg two times daily for 12 weeks or less if the gastric ulcer had completely healed." | 5.06 | Healing of gastric ulcer in the elderly: a double-blind study of cetraxate versus ranitidine. ( Lee, YC; Ng, NS; Tam, HC; Wong, HY, 1989) |
| "We investigated the effect of the anti-ulcer drug cetraxate on the development of the gastric ulcer induced by the submucosal injection of endothelin-1 in the rat gastric body, and its effects on gastric mucosal hemodynamics and tissue oxygenation by Laser doppler flowmetry and tissue spectrophotometry." | 3.68 | Endothelin-1-induced gastric ulcer is attenuated by cetraxate. ( Fukutomi, H; Goto, K; Kashimura, H; Lazaratos, S; Miyauchi, T; Nakahara, A; Osuga, T, 1993) |
| " The several trans-GMCHA arylamide derivatives showed more potent inhibitory effects on the stress- and HCl-ethanol-induced gastric ulcers than cetraxate in rats." | 3.68 | Syntheses and inhibitory effects on gastric lesions of trans-guanidinomethylcyclohexane carboxylic acid arylamides. ( Ikeda, T; Kakegawa, H; Matsumoto, H; Miyataka, H; Momoi, Y; Satoh, T; Ueda, H, 1993) |
| "The effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on various experimental gastric ulcers and gastric secretion in experimental animals was compared with that of cimetidine and cetraxate." | 3.67 | Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. ( Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F, 1984) |
| " prevented formation of ulcers induced by serotonin, indomethacin, acetylsalicylic acid or stress (acute ulcer models), its effect being greater against gastric ulcers induced by serotonin." | 3.67 | Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103). ( Hoshina, K; Naruchi, T; Takeshita, T; Yamazaki, N, 1985) |
| " To determine whether or not the anti-ulcer action of cetraxate hydrochloride was due to the unchanged drug, PHPA, or tranexamic acid, studies with aspirin and water-immersion -induced gastric ulcers in rats were performed." | 3.67 | [Pharmacokinetic and pharmacological studies on cetraxate, an anti-ulcer agent]. ( Naito, S; Tanaka, H, 1985) |
| "Cetraxate treatment increased NO synthase activity throughout the experiment in rats with or without stress treatment." | 1.29 | Prevention of water immersion stress-induced gastric lesions through the enhancement of nitric oxide synthase activity in rats. ( Goto, H; Hayakawa, T; Sugiyama, S; Tachi, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (45.00) | 18.7374 |
| 1990's | 9 (45.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Higuchi, K | 1 |
| Watanabe, T | 1 |
| Tanigawa, T | 1 |
| Shiba, M | 1 |
| Tominaga, K | 1 |
| Fujiwara, Y | 1 |
| Oshitani, N | 1 |
| Arakawa, T | 1 |
| Ueda, F | 1 |
| Aratani, S | 1 |
| Mimura, K | 1 |
| Kimura, K | 1 |
| Nomura, A | 1 |
| Enomoto, H | 1 |
| Itoh, M | 1 |
| Matsuo, Y | 1 |
| Ishizuka, Y | 1 |
| Kamisaki, T | 1 |
| Matsuda, M | 1 |
| Shimazaki, I | 1 |
| Kawashima, M | 1 |
| Yaginuma, H | 1 |
| Terashima, K | 1 |
| Sato, M | 1 |
| Lazaratos, S | 1 |
| Kashimura, H | 1 |
| Nakahara, A | 1 |
| Fukutomi, H | 1 |
| Osuga, T | 1 |
| Miyauchi, T | 1 |
| Goto, K | 1 |
| Ueda, H | 2 |
| Ikeda, T | 2 |
| Kakegawa, H | 2 |
| Miyataka, H | 2 |
| Matsumoto, H | 2 |
| Satoh, T | 2 |
| Momoi, Y | 1 |
| Tachi, K | 1 |
| Goto, H | 2 |
| Hayakawa, T | 1 |
| Sugiyama, S | 2 |
| Adachi, K | 1 |
| Suetsugu, H | 1 |
| Moriyama, N | 1 |
| Kazumori, H | 1 |
| Kawamura, A | 1 |
| Fujishiro, H | 1 |
| Sato, H | 1 |
| Okuyama, T | 1 |
| Ishihara, S | 1 |
| Watanabe, M | 1 |
| Kinoshita, Y | 1 |
| Suzuki, Y | 1 |
| Ito, M | 1 |
| Sudo, Y | 1 |
| Ito, S | 1 |
| Murakami, T | 1 |
| Kambara, T | 1 |
| Kishi, S | 1 |
| Hashizume, T | 1 |
| Aibara, S | 1 |
| Hirokawa, K | 1 |
| Nishida, A | 2 |
| Ogawa, H | 1 |
| Kasahara, A | 1 |
| Miyata, K | 1 |
| Kamato, T | 1 |
| Honda, K | 1 |
| Kuroiwa, M | 1 |
| Tsukamoto, Y | 1 |
| Nakazawa, S | 1 |
| Ozawa, T | 1 |
| Onoda, Y | 1 |
| Takido, M | 1 |
| Magaribuchi, T | 1 |
| Tamaki, H | 1 |
| Tam, HC | 1 |
| Lee, YC | 1 |
| Wong, HY | 1 |
| Ng, NS | 1 |
| Maeda, T | 1 |
| Hoshina, K | 1 |
| Yamazaki, N | 1 |
| Takeshita, T | 1 |
| Naruchi, T | 1 |
| Wilairatana, S | 1 |
| Kladchareon, N | 1 |
| Kositsurunkakul, S | 1 |
| Israsena, S | 1 |
| Tanaka, H | 1 |
| Naito, S | 1 |
4 trials available for cetraxate and Stomach Ulcer
| Article | Year |
|---|---|
Gastric ulcer treatment with intravenous human epidermal growth factor: a double-blind controlled clinical study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-Blind Me | 1994 |
Influence of Helicobacter pylori infection and cetraxate on gastric mucosal blood flow during healing of endoscopic mucosal resection-induced ulcers.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anti-Ulcer Agents; Female; Gastric | 2001 |
Healing of gastric ulcer in the elderly: a double-blind study of cetraxate versus ranitidine.
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; China; Clinical Trials as Topic; Cyclohexanecarboxylic A | 1989 |
Cetraxate and antacid in the treatment of gastric ulcer. A controlled clinical trial.
Topics: Adult; Aged; Antacids; Anti-Ulcer Agents; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fem | 1985 |
16 other studies available for cetraxate and Stomach Ulcer
| Article | Year |
|---|---|
Are gastroprotective drugs useful for gastric ulcer healing: re-evaluation using current ICH E9 guidelines.
Topics: Anti-Ulcer Agents; Gastric Mucosa; Guidelines as Topic; Humans; Randomized Controlled Trials as Topi | 2007 |
Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Female; Gastric Acid; Gastric Mucosa; | 1984 |
Anti-ulcer effect of 1,6-dihydro-2-[2-(2-methylpropoxy) anilino]-6-oxo-5-pyrimidinecarboxylic acid on experimental gastric ulcers in rats.
Topics: Acetates; Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Ethanol; Hydrochloric Acid; Male; p-Metho | 1994 |
Endothelin-1-induced gastric ulcer is attenuated by cetraxate.
Topics: Animals; Anti-Ulcer Agents; Endothelins; Gastric Mucosa; Hemodynamics; Male; Rats; Rats, Wistar; Sto | 1993 |
Syntheses and inhibitory effects on gastric lesions of 4-guanidinomethylbenzoic acid arylamides.
Topics: Animals; Anti-Ulcer Agents; Benzamides; Guanidines; Male; Mice; Mice, Inbred ICR; Rats; Rats, Spragu | 1993 |
Syntheses and inhibitory effects on gastric lesions of trans-guanidinomethylcyclohexane carboxylic acid arylamides.
Topics: Animals; Anti-Ulcer Agents; Benzoates; Carbanilides; Cimetidine; Cyclohexanecarboxylic Acids; Gastri | 1993 |
Prevention of water immersion stress-induced gastric lesions through the enhancement of nitric oxide synthase activity in rats.
Topics: Animals; Anti-Ulcer Agents; Gastric Mucosa; Immersion; Male; Nitric Oxide Synthase; omega-N-Methylar | 1996 |
Studies on the mechanism of action of cetraxate [4'-(2-carboxyethyl)phenyl trans-4-aminomethyl cyclohexanecarboxylate hydrochloride], a new anti-ulcer agent.
Topics: Acetates; Animals; Anti-Ulcer Agents; Aspirin; Connective Tissue; Cyclohexanecarboxylic Acids; Femal | 1979 |
Therapeutic effect of cetraxate on gastric ulcers (Phase I).
Topics: Cyclohexanecarboxylic Acids; Humans; Stomach Ulcer; Tranexamic Acid | 1979 |
Protective effect of cetraxate, a new antiulcer drug, against serotonin-induced ulcer.
Topics: Animals; Anti-Ulcer Agents; Aorta; Cyclohexanecarboxylic Acids; Gastric Emptying; Gastric Mucosa; Ga | 1979 |
Studies on the mechanism for the gastric mucosal protection by famotidine in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Famotidine; Gastric Mucosa; Male; Pirenzepine; Rats; Rats, I | 1991 |
The role of mucosal prostaglandin levels in healing of water immersion-induced gastric ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Gastric Mucosa; Immersion; Male; Prostaglandins; Rats; Rats, Inbred Stra | 1990 |
Effects of 12-sulfodehydroabietic acid monosodium salt (TA-2711), a new anti-ulcer agent, on gastric mucosal lesions induced by necrotizing agents and gastric mucosal defensive factors in rats.
Topics: Abietanes; Animals; Anti-Ulcer Agents; Dinoprostone; Diterpenes; Gastric Acid; Gastric Mucosa; Male; | 1990 |
[A study on pathogenesis of gastric ulcer in patient with liver cirrhosis: with special reference to the gastric mucosal blood flow].
Topics: Adult; Anti-Ulcer Agents; Gastric Mucosa; Humans; Liver Cirrhosis; Middle Aged; Regional Blood Flow; | 1988 |
Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103).
Topics: Acetates; Acetic Acid; Aminopyrine; Animals; Anti-Ulcer Agents; Aspirin; Bethanechol Compounds; Cime | 1985 |
[Pharmacokinetic and pharmacological studies on cetraxate, an anti-ulcer agent].
Topics: Animals; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Hydro | 1985 |