cetirizine has been researched along with Urticaria in 180 studies
Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.
Urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adult patients presenting to EDs and urgent care centers with acute urticaria requiring an intravenous antihistamine were randomized to either intravenous cetirizine 10 mg or intravenous diphenhydramine 50 mg." | 9.34 | Intravenous Cetirizine Versus Intravenous Diphenhydramine for the Treatment of Acute Urticaria: A Phase III Randomized Controlled Noninferiority Trial. ( Abella, BS; Berger, WE; Blaiss, MS; Caterino, JM; Du, J; Herres, JP; Kessler, A; Klausner, HA; Moellman, JJ; Stiell, IG; Suner, S, 2020) |
| "The addition of a prednisone burst did not improve the symptomatic and clinical response of acute urticaria to levocetirizine." | 9.27 | Levocetirizine and Prednisone Are Not Superior to Levocetirizine Alone for the Treatment of Acute Urticaria: A Randomized Double-Blind Clinical Trial. ( Barniol, C; Charpentier, S; Dehours, E; Houze-Cerfon, CH; Lauque, D; Mallet, J, 2018) |
| "Combination of cetirizine with ranitidine was not more effective than cetirizine alone in chronic urticaria." | 9.20 | Safety and efficacy of cetirizine versus cetirizine plus ranitidine in chronic urticaria: Double-blind randomized placebo-controlled study. ( Bonilla-Lopez, S; Guevara-Gutierrez, E; Hernández-Arana, S; Tlacuilo-Parra, A, 2015) |
| "Cetirizine is commonly used in the treatment of urticaria." | 9.19 | Clinical effectiveness and safety of cetirizine versus rupatadine in chronic spontaneous urticaria: a randomized, double-blind, 6-week trial. ( Dakhale, GN; Hiware, SK; Mahatme, MS; Mishra, DB; Mukhi, JI; Salve, AM; Shinde, AT, 2014) |
| " Efficacy and safety of doubling the dose of cetirizine were compared with olopatadine in the patients with symptoms like wheal or itching, despite the treatment with the standard dose of cetirizine." | 9.17 | Double dose of cetirizine hydrochloride is effective for patients with urticaria resistant: a prospective, randomized, non-blinded, comparative clinical study and assessment of quality of life. ( Okubo, Y; Shigoka, Y; Tsuboi, R; Yamazaki, M, 2013) |
| "Levocetirizine led to a significantly greater decrease in pruritus severity than desloratadine over the first treatment week; mean pruritus severity scores of 1." | 9.14 | Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients. ( Finlay, AY; Guillet, G; Hauptmann, P; Jian, AM; Kapp, A; Maurer, M; Potter, PC, 2009) |
| "Bilastine is a novel nonsedative H(1)-receptor antagonist, which may be used for the symptomatic treatment of chronic idiopathic urticaria (CU)." | 9.14 | Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study. ( Antépara, I; Bogacka, E; Jáuregui, I; Medina, I; Oanta, A; Uhl, P; Valiente, R; Wesel, F; Zuberbier, T, 2010) |
| "Eighty tertiary referral patients with chronic urticaria (age range, 19-67 years) were randomized for double-blind treatment with levocetirizine or desloratadine (40/40)." | 9.14 | The effectiveness of levocetirizine and desloratadine in up to 4 times conventional doses in difficult-to-treat urticaria. ( Church, DS; Church, MK; Dimitrov, V; Kraeva, S; Kralimarkova, T; Lazarova, C; Popov, TA; Popova, D; Staevska, M, 2010) |
| "To determine whether levocetirizine is efficacious in the treatment of chronic idiopathic urticaria." | 9.12 | Levocetirizine in the treatment of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study. ( Barra, L; Colanardi, MC; Ferrannini, A; Nettis, E; Tursi, A; Vacca, A, 2006) |
| "A double-blinded, placebo-controlled trial comparing cetirizine 10 mg daily in combination with zafirlukast 20 mg twice a day versus cetirizine 10 mg daily and placebo was conducted to determine whether subjects with chronic urticaria benefit from add-on therapy with a leukotriene-modifying agent." | 9.11 | The addition of zafirlukast to cetirizine improves the treatment of chronic urticaria in patients with positive autologous serum skin test results. ( Bagenstose, SE; Bernstein, JA; Levin, L, 2004) |
| "We compared the efficacy and tolerability of cetirizine in patients with idiopathic chronic urticaria to the more widely used antihistamine, oxatomide." | 9.09 | Double-blind multicenter study on the efficacy and tolerability of cetirizine compared with oxatomide in chronic idiopathic urticaria in preschool children. ( Barberio, G; Corrias, A; Grimaldi, I; La Rosa, M; Leonardi, S; Marchese, G; Oggiano, N, 2001) |
| "The results of this comparative study demonstrate that montelukast orally administered once a day is very effective for the treatment of cutaneous symptoms in patients with chronic urticaria due to food additives and/or ASA." | 9.09 | Efficacy of leukotriene receptor antagonist in chronic urticaria. A double-blind, placebo-controlled comparison of treatment with montelukast and cetirizine in patients with chronic urticaria with intolerance to food additive and/or acetylsalicylic acid. ( Corrocher, R; Di Lorenzo, G; Pacor, ML, 2001) |
| "In order to examine the efficacy of cetirizine in cholinergic urticaria, we studied 24 patients in a double-blind crossover design during 3-week treatment periods, with either 10 or 20 mg/d cetirizine or placebo." | 9.08 | Efficacy of cetirizine in cholinergic urticaria. ( Aberer, W; Burtin, B; Czarnetzki, BM; Rihoux, JP; Zuberbier, T, 1995) |
| "Cetirizine and astemizole have been shown to be safe and effective in the treatment of patients with chronic idiopathic urticaria." | 9.08 | Cetirizine and astemizole therapy for chronic idiopathic urticaria: a double-blind, placebo-controlled, comparative trial. ( Breneman, D; Bronsky, EA; Bruce, S; Kalivas, JT; Klein, GL; Roth, HL; Soter, N; Tharp, MD; Treger, C, 1995) |
| "In a randomized, double-blind, parallel-group study in 16 patients with chronic urticaria, we investigated the pharmacokinetics and suppressive effect on the histamine-induced wheal and flare of a single dose of hydroxyzine 25 mg or cetirizine 10 mg, given before and after treatment with cimetidine 600 mg every 12 hours for 10 days." | 9.08 | Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria. ( Simons, FE; Simons, KJ; Sussman, GL, 1995) |
| "To compare the safety and efficacy of cetirizine with that of hydroxyzine and placebo in the treatment of chronic idiopathic urticaria." | 9.08 | Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria. ( Breneman, DL, 1996) |
| "Clinical trials of a new histamine H1-blocker of the III generation zyrtec (cetirizine) manufactured in Belgium (UCB) demonstrated its high efficacy in pollenosis and chronic idiopathic urticaria." | 9.07 | [The efficacy of the Zirtek (cetirizine) preparation in chronic recurrent urticaria and seasonal allergic rhinitis]. ( Androsov, VN; Belostotskaia, OI; Il'ina, NI, 1994) |
| "The effect of cetirizine, 10 mg at night, on dermographic urticaria, was studied in 19 patients." | 9.07 | The effect of cetirizine on symptoms and wealing in dermographic urticaria. ( Sharpe, GR; Shuster, S, 1993) |
| "Our randomised study in parallel groups, double-blind double placebo, has compared the efficacy, onset of action and safety of terfenadine and cetirizine in chronic idiopathic urticaria." | 9.07 | [Double-blind comparative study of terfenadine and cetirizine in chronic idiopathic urticaria]. ( Bloom, M; Danglas, P; Hantzperg, M; Lambert, D, 1993) |
| "In a 20-d, double-blind, randomized, parallel study, the efficacy of cetirizine and terfenadine was compared in 30 patients with chronic idiopathic urticaria." | 9.07 | A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria. ( Andri, G; Andri, L; Betteli, C; Givanni, S; Lombardi, C; Mezzelani, P; Senna, GE, 1993) |
| "Cetirizine, a peripheral H1 antagonist, was administered to patients with delayed pressure urticaria in a double-blind, placebo-controlled, crossover study." | 9.07 | Therapeutic effects of cetirizine in delayed pressure urticaria: clinicopathologic findings. ( Aroni, K; Demaka, P; Gonianakis, M; Kontou-Fili, K; Maniatakou, G; Palaiologos, G, 1991) |
| "The efficacy of cetirizine dihydrochloride, a new H1-antagonist claimed to have minimal sedative property was evaluated in 28 patients with chronic idiopathic urticaria." | 9.07 | Cetirizine vs placebo in chronic idiopathic urticaria--a double blind randomised cross-over study. ( Goh, CL; Lim, J; Wong, WK, 1991) |
| "The efficacy of cetirizine dihydrochloride, a new H1-antagonist with minimal sedative or anticholinergic side effects was evaluated in 30 patients with chronic idiopathic urticaria." | 9.06 | Treatment of chronic urticaria with cetirizine dihydrochloride a non-sedating antihistamine. ( Arendt, C; Juhlin, L, 1988) |
| "Bilastine is an orally administered, second-generation antihistamine used in the symptomatic treatment of seasonal or perennial allergic rhinoconjunctivitis and urticaria." | 8.88 | Bilastine: in allergic rhinitis and urticaria. ( Carter, NJ, 2012) |
| "Only recently available on the US market, levocetirizine has emerged as an effective new option in the treatment of chronic idiopathic urticaria (CIU)." | 8.85 | Levocetirizine for chronic idiopathic urticaria: a review. ( Ducharme, EE; Weinberg, JM, 2009) |
| "Levocetirizine (LCZ) is a second-generation antihistamine that was approved in January 2008 for the relief of symptoms of seasonal allergic rhinitis (SAR), perennial allergic rhinitis (PAR), and chronic idiopathic urticaria (CIU) in adults and children aged > or = 6 years." | 8.85 | Levocetirizine for the treatment of allergic rhinitis and chronic idiopathic urticaria in adults and children. ( Borja-Hart, N; Ghin, HL; Perez, A; Robles, GI; Singh-Franco, D, 2009) |
| "H1-receptor inhibiting drugs, namely loratadine and cetirizine, were frequently used in treatment of chronic urticaria." | 7.80 | Effects of loratadine and cetirizine on serum levels of neuropeptides in patients with chronic urticaria. ( Başak, PY; Buyukbayram, HI; Erturan, I; Kazanoglu, OO; Vural, H, 2014) |
| "We investigated the suitability of cetirizine HCl (cetirizine) for the initial treatment of chronic urticaria." | 7.74 | Evaluation of cetirizine hydrochloride-based therapeutic strategy for chronic urticaria. ( Ando, K; Azumi, T; Hirai, S; Kamiya, S; Kondo, T; Masaki, S; Mori, T; Nitta, Y; Sugiura, K; Suzuki, T; Tomita, Y; Usuda, T; Yokoi, T, 2008) |
| "In addition to histamine, leukotriene C4 (LTC4) might also play a role in mediating cold urticaria wheals." | 7.74 | Histamine, but not leukotriene C4, is an essential mediator in cold urticaria wheals. ( Ackermann, L; Harvima, IT; Nuutinen, P, 2007) |
| "To determine if 6 weeks of therapy with levocetirizine 5 mg once daily would also induce any decrease in serum levels of intercellular adhesion molecule-1, vascular cell adhesion molecule-1, endothelial leucocyte adhesion molecule-1 (ELAM-1) or P-selectin in subjects with CU and chronic autoimmune urticaria." | 7.73 | Cellular adhesion molecules in chronic urticaria: modulation of serum levels occurs during levocetirizine treatment. ( Caproni, M; Del Bianco, E; Fabbri, P; Giomi, B; Torchia, D; Volpi, W, 2006) |
| "Treating chronic idiopathic urticaria with levocetirizine is a dominant strategy for society since it is more effective (in terms of pruritus-free days gained) and less costly than placebo." | 7.73 | Cost effectiveness of levocetirizine in chronic idiopathic urticaria : a pooled analysis of two randomised controlled trials. ( Demarteau, N; Kapp, A, 2006) |
| "A patient with recurrent idiopathic urticaria reported exacerbations after treatment with cetirizine." | 7.71 | Urticaria to cetirizine. ( Bartra, J; Gaig, P; Garcia-Ortega, P; Tella, R, 2002) |
| "The paradoxical acute exacerbation of pre-existing chronic idiopathic urticaria accompanied by intense generalized pruritus, facial oedema, and dyspnoea in a 36-year-old-woman 3-4 h after a single oral dose of 10 mg cetirizine (Zyrtec tablets), suggested the presence of an underlying intolerance reaction." | 7.71 | Urticarial intolerance reaction to cetirizine. ( Damveld, B; Marsch, WC; Schröter, S, 2002) |
| "The effects of oral administration of the antihistamine cetirizine on the weal and flare caused by intradermal injection of platelet activating factor (PAF-acether), kallikrein, histamine and the patient's own serum were investigated in 10 patients with chronic urticaria." | 7.68 | Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria. ( Juhlin, L; Rihoux, JP, 1990) |
| "Bilastine is a recently introduced, non-sedative H1-antihistamine for its treatment." | 6.94 | Effectiveness, safety, and tolerability of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic spontaneous urticaria: A double-blind, parallel group, randomized controlled trial. ( Biswas, D; Chowdhury, SN; Das, A; Ghosh, S; Podder, I; Sengupta, S, 2020) |
| "Levocetirizine was found to be more efficacious than rupatadine in CIU patients, but both drugs caused mild sedation." | 6.80 | Levocetirizine and rupatadine in chronic idiopathic urticaria. ( Badyal, DK; Johnson, M; Kwatra, G; Thomas, EA, 2015) |
| " Routine hematological and biochemical tests and treatment-emergent adverse events were monitored for safety." | 6.78 | Olopatadine versus levocetirizine in chronic urticaria: an observer-blind, randomized, controlled trial of effectiveness and safety. ( Bagchi, C; Chaudhuri, A; Das, NK; Hazra, A; Islam, CN; Sil, A; Tripathi, SK, 2013) |
| "Rupatadine is a better choice in CIU in comparison to levocetirizine due to better efficacy and safety profile." | 6.76 | Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety. ( Ahmed, I; Goud, P; Jaida, J; Maiti, R; Palani, A; Raghavendra, BN, 2011) |
| "Levocetirizine has been shown in observational studies in the west as an effective and satisfactory therapy for patients with allergic respiratory and skin disease." | 6.75 | An open-label, multicentre study of levocetirizine for the treatment of allergic rhinitis and urticaria in Taiwanese patients. ( Fang, SY; Huangs, CY; Lee, JY; Lin, DY; Perng, DW, 2010) |
| "Chronic urticaria was related to the immune unbalance of body." | 6.73 | [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. ( Fang, ZD; Jin, CY; Wang, DL, 2008) |
| "Chronic urticaria is a prevalent condition associated with substantial disability." | 6.72 | Theophylline as 'add-on' therapy to cetirizine in patients with chronic idiopathic urticaria. A randomized, double-blind, placebo-controlled pilot study. ( Gregoriou, S; Kalogeromitros, D; Katsarou-Katsari, A; Kempuraj, D; Makris, M; Papaliodis, D; Theoharides, TC, 2006) |
| "Levocetirizine is an antihistamine from the latest generation approved for CIU." | 6.72 | Levocetirizine is an effective treatment in patients suffering from chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled, parallel, multicenter study. ( Kapp, A; Pichler, WJ, 2006) |
| " At the dosage used, cetirizine therapy appears to be no more effective than terfenadine." | 6.67 | A comparison of cetirizine and terfenadine in the management of solar urticaria. ( Bilsland, D; Ferguson, J, 1991) |
| "Chronic urticaria is a problem for both physician and patient." | 6.67 | Urticaria: clinical efficacy of cetirizine in comparison with hydroxyzine and placebo. ( Bigby, M; Breneman, D; Bruce, S; Kalivas, J; Tharp, M, 1990) |
| "Cetirizine is a new H1 antagonist with potent inhibitory action against the infiltration of eosinophils into involved tissue, thereby affecting the late-phase reaction." | 6.38 | Cetirizine: a new H1 antagonist with antieosinophilic activity in chronic urticaria. ( Townley, RG, 1991) |
| "Adult patients presenting to EDs and urgent care centers with acute urticaria requiring an intravenous antihistamine were randomized to either intravenous cetirizine 10 mg or intravenous diphenhydramine 50 mg." | 5.34 | Intravenous Cetirizine Versus Intravenous Diphenhydramine for the Treatment of Acute Urticaria: A Phase III Randomized Controlled Noninferiority Trial. ( Abella, BS; Berger, WE; Blaiss, MS; Caterino, JM; Du, J; Herres, JP; Kessler, A; Klausner, HA; Moellman, JJ; Stiell, IG; Suner, S, 2020) |
| "Recently, several authors have suggested an off-label increase of antihistamine dosage should be given to patients with chronic urticaria (CU) not responding to the usual, recommended doses, in order to gain better control of the disease." | 5.34 | Chronic unremitting urticaria: is the use of antihistamines above the licensed dose effective? A preliminary study of cetirizine at licensed and above-licensed doses. ( Asero, R, 2007) |
| "Acquired cold urticaria is an infrequent physical urticaria that can provoke severe systemic reactions." | 5.32 | Treatment of acquired cold urticaria with cetirizine and zafirlukast in combination. ( Bonadonna, P; Canonica, GW; Lombardi, C; Passalacqua, G; Senna, G, 2003) |
| " Two-hundred and forty patients with acute urticaria admitted to emergency department will be randomised in a 1:1 ratio to receive levocetirizine or an association of levocetirizine and prednisone." | 5.30 | Glucocorticoids for acute urticaria: study protocol for a double-blind non-inferiority randomised controlled trial. ( Adnet, F; Bagot, M; Berard, F; Bouillet, L; Casalino, E; Caux, F; Chosidow, O; Descamps, V; Doutre, MS; Fain, O; Fontaine, JP; Gil-Jardine, C; Goulet, H; Javaud, N; Khellaf, M; Lapostolle, F; Maignan, M; Martin, L; Pateron, D; Roy, PM; Soria, A; Tazarourte, K; Vicaut, E, 2019) |
| "The addition of a prednisone burst did not improve the symptomatic and clinical response of acute urticaria to levocetirizine." | 5.27 | Levocetirizine and Prednisone Are Not Superior to Levocetirizine Alone for the Treatment of Acute Urticaria: A Randomized Double-Blind Clinical Trial. ( Barniol, C; Charpentier, S; Dehours, E; Houze-Cerfon, CH; Lauque, D; Mallet, J, 2018) |
| "Combination of cetirizine with ranitidine was not more effective than cetirizine alone in chronic urticaria." | 5.20 | Safety and efficacy of cetirizine versus cetirizine plus ranitidine in chronic urticaria: Double-blind randomized placebo-controlled study. ( Bonilla-Lopez, S; Guevara-Gutierrez, E; Hernández-Arana, S; Tlacuilo-Parra, A, 2015) |
| "Cetirizine is commonly used in the treatment of urticaria." | 5.19 | Clinical effectiveness and safety of cetirizine versus rupatadine in chronic spontaneous urticaria: a randomized, double-blind, 6-week trial. ( Dakhale, GN; Hiware, SK; Mahatme, MS; Mishra, DB; Mukhi, JI; Salve, AM; Shinde, AT, 2014) |
| "To test this belief by comparing the effectiveness and prevalence of unwanted sedative effects when treating patients with chronic spontaneous urticaria (CSU) with levocetirizine 15 mg daily plus hydroxyzine 50 mg at night (levocetirizine plus hydroxyzine) vs." | 5.19 | Night-time sedating H1 -antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial. ( Church, MK; Dimitrov, V; Gugutkova, M; Kralimarkova, T; Lazarova, C; Popov, TA; Staevska, M; Zuberbier, T, 2014) |
| " Efficacy and safety of doubling the dose of cetirizine were compared with olopatadine in the patients with symptoms like wheal or itching, despite the treatment with the standard dose of cetirizine." | 5.17 | Double dose of cetirizine hydrochloride is effective for patients with urticaria resistant: a prospective, randomized, non-blinded, comparative clinical study and assessment of quality of life. ( Okubo, Y; Shigoka, Y; Tsuboi, R; Yamazaki, M, 2013) |
| "Levocetirizine led to a significantly greater decrease in pruritus severity than desloratadine over the first treatment week; mean pruritus severity scores of 1." | 5.14 | Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients. ( Finlay, AY; Guillet, G; Hauptmann, P; Jian, AM; Kapp, A; Maurer, M; Potter, PC, 2009) |
| "Bilastine is a novel nonsedative H(1)-receptor antagonist, which may be used for the symptomatic treatment of chronic idiopathic urticaria (CU)." | 5.14 | Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study. ( Antépara, I; Bogacka, E; Jáuregui, I; Medina, I; Oanta, A; Uhl, P; Valiente, R; Wesel, F; Zuberbier, T, 2010) |
| "The therapeutic effects of AAG and cetirizine on chronic urticaria patients allocated in two groups were observed respectively, and the serum levels of RANTES, Eotaxin and TNF-alpha in patients were measured by ELISA before and after treatment, and were compared with those in normal subjects." | 5.14 | [Therapeutic effect of anti-anaphylaxis granule on chronic urticaria and its impact on serum levels of RANTES]. ( Fang, CY; Li, XM; Shi, LH, 2009) |
| "Eighty tertiary referral patients with chronic urticaria (age range, 19-67 years) were randomized for double-blind treatment with levocetirizine or desloratadine (40/40)." | 5.14 | The effectiveness of levocetirizine and desloratadine in up to 4 times conventional doses in difficult-to-treat urticaria. ( Church, DS; Church, MK; Dimitrov, V; Kraeva, S; Kralimarkova, T; Lazarova, C; Popov, TA; Popova, D; Staevska, M, 2010) |
| "To determine whether levocetirizine is efficacious in the treatment of chronic idiopathic urticaria." | 5.12 | Levocetirizine in the treatment of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study. ( Barra, L; Colanardi, MC; Ferrannini, A; Nettis, E; Tursi, A; Vacca, A, 2006) |
| "To study the effect of long-term treatment with the H1-antihistamine levocetirizine on urticaria in young atopic children." | 5.12 | H1-antihistamine treatment in young atopic children: effect on urticaria. ( Simons, FE, 2007) |
| "A double-blinded, placebo-controlled trial comparing cetirizine 10 mg daily in combination with zafirlukast 20 mg twice a day versus cetirizine 10 mg daily and placebo was conducted to determine whether subjects with chronic urticaria benefit from add-on therapy with a leukotriene-modifying agent." | 5.11 | The addition of zafirlukast to cetirizine improves the treatment of chronic urticaria in patients with positive autologous serum skin test results. ( Bagenstose, SE; Bernstein, JA; Levin, L, 2004) |
| "Cetirizine and desloratadine are antihistamines active in the treatment of symptoms associated with seasonal allergic rhinitis and chronic urticaria." | 5.11 | Comparative activity of cetirizine and desloratadine on histamine-induced wheal-and-flare responses during 24 hours. ( Frossard, N; Melac, M; Pauli, G; Purohit, A, 2004) |
| "The pharmacokinetic/pharmacodynamic profile of levocetirizine was studied in 15 toddlers suffering from recurrent cough and other allergy-related symptoms, aged 20." | 5.11 | Levocetirizine in 1-2 year old children: pharmacokinetic and pharmacodynamic profile. ( Cranswick, N; Fuchs, M; Hulhoven, R; Turzíkova, J, 2005) |
| "Levocetirizine is the active enantiomer of cetirizine, a potent drug with little metabolism widely used for allergic rhinitis and urticaria." | 5.10 | A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects. ( DeVos, C; Grant, JA; Moulaert, B; Riethuisen, JM, 2002) |
| "Our objective was to study the effect of long-term treatment with the H(1)-receptor antagonist cetirizine in the prevention of urticaria in young children with atopic dermatitis." | 5.09 | Prevention of acute urticaria in young children with atopic dermatitis. ( Simons, FE, 2001) |
| "We compared the efficacy and tolerability of cetirizine in patients with idiopathic chronic urticaria to the more widely used antihistamine, oxatomide." | 5.09 | Double-blind multicenter study on the efficacy and tolerability of cetirizine compared with oxatomide in chronic idiopathic urticaria in preschool children. ( Barberio, G; Corrias, A; Grimaldi, I; La Rosa, M; Leonardi, S; Marchese, G; Oggiano, N, 2001) |
| "The results of this comparative study demonstrate that montelukast orally administered once a day is very effective for the treatment of cutaneous symptoms in patients with chronic urticaria due to food additives and/or ASA." | 5.09 | Efficacy of leukotriene receptor antagonist in chronic urticaria. A double-blind, placebo-controlled comparison of treatment with montelukast and cetirizine in patients with chronic urticaria with intolerance to food additive and/or acetylsalicylic acid. ( Corrocher, R; Di Lorenzo, G; Pacor, ML, 2001) |
| "In order to examine the efficacy of cetirizine in cholinergic urticaria, we studied 24 patients in a double-blind crossover design during 3-week treatment periods, with either 10 or 20 mg/d cetirizine or placebo." | 5.08 | Efficacy of cetirizine in cholinergic urticaria. ( Aberer, W; Burtin, B; Czarnetzki, BM; Rihoux, JP; Zuberbier, T, 1995) |
| "Cetirizine and astemizole have been shown to be safe and effective in the treatment of patients with chronic idiopathic urticaria." | 5.08 | Cetirizine and astemizole therapy for chronic idiopathic urticaria: a double-blind, placebo-controlled, comparative trial. ( Breneman, D; Bronsky, EA; Bruce, S; Kalivas, JT; Klein, GL; Roth, HL; Soter, N; Tharp, MD; Treger, C, 1995) |
| "In a randomized, double-blind, parallel-group study in 16 patients with chronic urticaria, we investigated the pharmacokinetics and suppressive effect on the histamine-induced wheal and flare of a single dose of hydroxyzine 25 mg or cetirizine 10 mg, given before and after treatment with cimetidine 600 mg every 12 hours for 10 days." | 5.08 | Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria. ( Simons, FE; Simons, KJ; Sussman, GL, 1995) |
| "To compare the safety and efficacy of cetirizine with that of hydroxyzine and placebo in the treatment of chronic idiopathic urticaria." | 5.08 | Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria. ( Breneman, DL, 1996) |
| "Clinical trials of a new histamine H1-blocker of the III generation zyrtec (cetirizine) manufactured in Belgium (UCB) demonstrated its high efficacy in pollenosis and chronic idiopathic urticaria." | 5.07 | [The efficacy of the Zirtek (cetirizine) preparation in chronic recurrent urticaria and seasonal allergic rhinitis]. ( Androsov, VN; Belostotskaia, OI; Il'ina, NI, 1994) |
| "The effect of cetirizine, 10 mg at night, on dermographic urticaria, was studied in 19 patients." | 5.07 | The effect of cetirizine on symptoms and wealing in dermographic urticaria. ( Sharpe, GR; Shuster, S, 1993) |
| "Our randomised study in parallel groups, double-blind double placebo, has compared the efficacy, onset of action and safety of terfenadine and cetirizine in chronic idiopathic urticaria." | 5.07 | [Double-blind comparative study of terfenadine and cetirizine in chronic idiopathic urticaria]. ( Bloom, M; Danglas, P; Hantzperg, M; Lambert, D, 1993) |
| "In a 20-d, double-blind, randomized, parallel study, the efficacy of cetirizine and terfenadine was compared in 30 patients with chronic idiopathic urticaria." | 5.07 | A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria. ( Andri, G; Andri, L; Betteli, C; Givanni, S; Lombardi, C; Mezzelani, P; Senna, GE, 1993) |
| "Cetirizine, a peripheral H1 antagonist, was administered to patients with delayed pressure urticaria in a double-blind, placebo-controlled, crossover study." | 5.07 | Therapeutic effects of cetirizine in delayed pressure urticaria: clinicopathologic findings. ( Aroni, K; Demaka, P; Gonianakis, M; Kontou-Fili, K; Maniatakou, G; Palaiologos, G, 1991) |
| "The efficacy of cetirizine dihydrochloride, a new H1-antagonist claimed to have minimal sedative property was evaluated in 28 patients with chronic idiopathic urticaria." | 5.07 | Cetirizine vs placebo in chronic idiopathic urticaria--a double blind randomised cross-over study. ( Goh, CL; Lim, J; Wong, WK, 1991) |
| "The efficacy of cetirizine dihydrochloride, a new H1-antagonist with minimal sedative or anticholinergic side effects was evaluated in 30 patients with chronic idiopathic urticaria." | 5.06 | Treatment of chronic urticaria with cetirizine dihydrochloride a non-sedating antihistamine. ( Arendt, C; Juhlin, L, 1988) |
| "Bilastine is an orally administered, second-generation antihistamine used in the symptomatic treatment of seasonal or perennial allergic rhinoconjunctivitis and urticaria." | 4.88 | Bilastine: in allergic rhinitis and urticaria. ( Carter, NJ, 2012) |
| "Only recently available on the US market, levocetirizine has emerged as an effective new option in the treatment of chronic idiopathic urticaria (CIU)." | 4.85 | Levocetirizine for chronic idiopathic urticaria: a review. ( Ducharme, EE; Weinberg, JM, 2009) |
| "Levocetirizine (LCZ) is a second-generation antihistamine that was approved in January 2008 for the relief of symptoms of seasonal allergic rhinitis (SAR), perennial allergic rhinitis (PAR), and chronic idiopathic urticaria (CIU) in adults and children aged > or = 6 years." | 4.85 | Levocetirizine for the treatment of allergic rhinitis and chronic idiopathic urticaria in adults and children. ( Borja-Hart, N; Ghin, HL; Perez, A; Robles, GI; Singh-Franco, D, 2009) |
| "Levocetirizine and desloratadine are newer antihistamines indicated for the treatment of allergic rhinitis and chronic idiopathic urticaria." | 4.82 | A review of the evidence from comparative studies of levocetirizine and desloratadine for the symptoms of allergic rhinitis. ( Canonica, GW; Passalacqua, G, 2005) |
| "The second-generation H1-receptor antagonists terfenadine, astemizole, loratadine, and cetirizine are important first-line drugs for the relief of symptoms in patients with allergic rhinoconjunctivitis or chronic urticaria and may eventually supplant the potentially sedating first-generation H1-receptor antagonists in the treatment of these disorders." | 4.78 | Recent advances in H1-receptor antagonist treatment. ( Simons, FE, 1990) |
| "Cetirizine hydrochloride is a second-generation H1 histamine antagonist with Food and Drug Administration approval for treatment of allergic rhinitis and urticaria." | 4.02 | Maternal Transfer of Cetirizine Into Human Milk. ( Baker, T; Datta, P; Hale, TW; Rewers-Felkins, K; Wilkerson, H, 2021) |
| " Cetirizine is a histamine H1 antagonist that is US Food and Drug Administration approved for the treatment of allergic rhinitis and urticaria and has common adverse effects of drowsiness and headaches." | 4.02 | A case report of sleep terrors exacerbated by cetirizine. ( Aziz, SG; Hussain, S, 2021) |
| "H1-receptor inhibiting drugs, namely loratadine and cetirizine, were frequently used in treatment of chronic urticaria." | 3.80 | Effects of loratadine and cetirizine on serum levels of neuropeptides in patients with chronic urticaria. ( Başak, PY; Buyukbayram, HI; Erturan, I; Kazanoglu, OO; Vural, H, 2014) |
| "We investigated the suitability of cetirizine HCl (cetirizine) for the initial treatment of chronic urticaria." | 3.74 | Evaluation of cetirizine hydrochloride-based therapeutic strategy for chronic urticaria. ( Ando, K; Azumi, T; Hirai, S; Kamiya, S; Kondo, T; Masaki, S; Mori, T; Nitta, Y; Sugiura, K; Suzuki, T; Tomita, Y; Usuda, T; Yokoi, T, 2008) |
| "In addition to histamine, leukotriene C4 (LTC4) might also play a role in mediating cold urticaria wheals." | 3.74 | Histamine, but not leukotriene C4, is an essential mediator in cold urticaria wheals. ( Ackermann, L; Harvima, IT; Nuutinen, P, 2007) |
| "To determine if 6 weeks of therapy with levocetirizine 5 mg once daily would also induce any decrease in serum levels of intercellular adhesion molecule-1, vascular cell adhesion molecule-1, endothelial leucocyte adhesion molecule-1 (ELAM-1) or P-selectin in subjects with CU and chronic autoimmune urticaria." | 3.73 | Cellular adhesion molecules in chronic urticaria: modulation of serum levels occurs during levocetirizine treatment. ( Caproni, M; Del Bianco, E; Fabbri, P; Giomi, B; Torchia, D; Volpi, W, 2006) |
| "Treating chronic idiopathic urticaria with levocetirizine is a dominant strategy for society since it is more effective (in terms of pruritus-free days gained) and less costly than placebo." | 3.73 | Cost effectiveness of levocetirizine in chronic idiopathic urticaria : a pooled analysis of two randomised controlled trials. ( Demarteau, N; Kapp, A, 2006) |
| "We report the case of a 46-year-old man who tolerated 50 mg per day of cetirizine for the treatment of chronic idiopathic urticaria." | 3.72 | High dose cetirizine: a case report. ( Nordness, M; Zacharisen, MC, 2003) |
| "A patient with recurrent idiopathic urticaria reported exacerbations after treatment with cetirizine." | 3.71 | Urticaria to cetirizine. ( Bartra, J; Gaig, P; Garcia-Ortega, P; Tella, R, 2002) |
| "The paradoxical acute exacerbation of pre-existing chronic idiopathic urticaria accompanied by intense generalized pruritus, facial oedema, and dyspnoea in a 36-year-old-woman 3-4 h after a single oral dose of 10 mg cetirizine (Zyrtec tablets), suggested the presence of an underlying intolerance reaction." | 3.71 | Urticarial intolerance reaction to cetirizine. ( Damveld, B; Marsch, WC; Schröter, S, 2002) |
| "The effects of oral administration of the antihistamine cetirizine on the weal and flare caused by intradermal injection of platelet activating factor (PAF-acether), kallikrein, histamine and the patient's own serum were investigated in 10 patients with chronic urticaria." | 3.68 | Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria. ( Juhlin, L; Rihoux, JP, 1990) |
| "Bilastine is a recently introduced, non-sedative H1-antihistamine for its treatment." | 2.94 | Effectiveness, safety, and tolerability of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic spontaneous urticaria: A double-blind, parallel group, randomized controlled trial. ( Biswas, D; Chowdhury, SN; Das, A; Ghosh, S; Podder, I; Sengupta, S, 2020) |
| "Levocetirizine was found to be more efficacious than rupatadine in CIU patients, but both drugs caused mild sedation." | 2.80 | Levocetirizine and rupatadine in chronic idiopathic urticaria. ( Badyal, DK; Johnson, M; Kwatra, G; Thomas, EA, 2015) |
| " These results suggest that double-dosed levocetirizine treatment suppresses histamine-induced skin symptoms more rapidly, profoundly and sustainably than conventionally dosed levocetirizine treatment." | 2.78 | A double dose of levocetirizine leads to better control of histamine-induced flare, wheal and itch in healthy donors. ( Kabashima, K; Miyachi, Y; Nakahigashi, K; Nakamizo, S; Tanizaki, H, 2013) |
| "Levocetirizine was more inhibitory than fexofenadine on wheal, flare and pruritus (p < 0." | 2.78 | The inhibition by levocetirizine and fexofenadine of the histamine-induced wheal and flare response in healthy Caucasian and Japanese volunteers. ( Church, MK; Maurer, M; Schoepke, N, 2013) |
| " Routine hematological and biochemical tests and treatment-emergent adverse events were monitored for safety." | 2.78 | Olopatadine versus levocetirizine in chronic urticaria: an observer-blind, randomized, controlled trial of effectiveness and safety. ( Bagchi, C; Chaudhuri, A; Das, NK; Hazra, A; Islam, CN; Sil, A; Tripathi, SK, 2013) |
| "Bilastine was faster in onset than cetirizine, inhibitions of wheal and flare at 1." | 2.76 | Comparative inhibition by bilastine and cetirizine of histamine-induced wheal and flare responses in humans. ( Church, MK, 2011) |
| "Rupatadine is a better choice in CIU in comparison to levocetirizine due to better efficacy and safety profile." | 2.76 | Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety. ( Ahmed, I; Goud, P; Jaida, J; Maiti, R; Palani, A; Raghavendra, BN, 2011) |
| "Levocetirizine has been shown in observational studies in the west as an effective and satisfactory therapy for patients with allergic respiratory and skin disease." | 2.75 | An open-label, multicentre study of levocetirizine for the treatment of allergic rhinitis and urticaria in Taiwanese patients. ( Fang, SY; Huangs, CY; Lee, JY; Lin, DY; Perng, DW, 2010) |
| "Chronic urticaria was related to the immune unbalance of body." | 2.73 | [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. ( Fang, ZD; Jin, CY; Wang, DL, 2008) |
| " Safety was assessed by: reporting of adverse events, numbers of children discontinuing the study because of adverse events, height and body mass measurements, assessment of developmental milestones, and hematology and biochemistry tests." | 2.73 | Safety of levocetirizine treatment in young atopic children: An 18-month study. ( Simons, FE, 2007) |
| "Levocetirizine was significantly more potent than desloratadine." | 2.73 | Inhibition of allergen-induced wheal and flare reactions by levocetirizine and desloratadine. ( Frossard, N; Pauli, G; Purohit, A; Strolin-Benedetti, M, 2008) |
| "Chronic urticaria is a prevalent condition associated with substantial disability." | 2.72 | Theophylline as 'add-on' therapy to cetirizine in patients with chronic idiopathic urticaria. A randomized, double-blind, placebo-controlled pilot study. ( Gregoriou, S; Kalogeromitros, D; Katsarou-Katsari, A; Kempuraj, D; Makris, M; Papaliodis, D; Theoharides, TC, 2006) |
| "Levocetirizine is an antihistamine from the latest generation approved for CIU." | 2.72 | Levocetirizine is an effective treatment in patients suffering from chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled, parallel, multicenter study. ( Kapp, A; Pichler, WJ, 2006) |
| "Levocetirizine (5 mg) is a potent inhibitor of the effects of histamine in human skin with an efficacy that exceeded that of loratadine (10 mg) when single doses of the drugs were administered 4 h before the test." | 2.70 | Comparison of the effects of levocetirizine and loratadine on histamine-induced wheal, flare, and itch in human skin. ( Boutsiouki, P; Church, MK; Clough, GF, 2001) |
| "Ebastine was no better than placebo until 4 h, but was efficacious thereafter until 24 h." | 2.69 | A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects. ( Danielson, L; DeVos, C; Grant, JA; Rihoux, JP, 1999) |
| "Cetirizine was found to be superior to acrivastine and loratadine for the suppression of wheal and flare responses at 240, 360 min and 24 h (P < 0." | 2.69 | Effects of acrivastine, loratadine and cetirizine on histamine-induced wheal and flare responses. ( Altintaş, L; Apaydýn, R; Bayramgürler, D; Bilen, N; Dökmeci, S; Sal, G; Utkan, T, 1999) |
| " At the dosage used, cetirizine therapy appears to be no more effective than terfenadine." | 2.67 | A comparison of cetirizine and terfenadine in the management of solar urticaria. ( Bilsland, D; Ferguson, J, 1991) |
| "Chronic urticaria is a problem for both physician and patient." | 2.67 | Urticaria: clinical efficacy of cetirizine in comparison with hydroxyzine and placebo. ( Bigby, M; Breneman, D; Bruce, S; Kalivas, J; Tharp, M, 1990) |
| "Cetirizine was significantly more effective than dexchlorpheniramine in suppressing the size of wheals from 2 to 24 h after drug administration." | 2.66 | Attenuation of cutaneous reactivity to histamine by cetirizine and dexchlorpheniramine. ( Botha, JJ; Groenewoud, G; Luus, HG; Müller, FO; van Dyk, M, 1988) |
| "Levocetirizine has modest sedative effects with a risk ratio of 1." | 2.55 | Sedative Effects of Levocetirizine: A Systematic Review and Meta-Analysis of Randomized Controlled Studies. ( Chitsuthipakorn, W; Khattiyawittayakun, L; Seresirikachorn, K; Snidvongs, K, 2017) |
| "Guidelines for the treatment of urticaria issued by Polish and international expert bodies were analyzed, along with the SPCs." | 2.49 | [Pharmacotherapy of urticaria--an analysis of the discrepancies between guidelines of expert bodies, registration documents and evidence for the effectiveness of drugs]. ( Plichta, D; Spiewak, R, 2013) |
| "Levocetirizine has several pharmacokinetic properties that are desirable for an antihistamine providing a combination of both potency and safety." | 2.47 | Pharmacokinetic evaluation of levocetirizine. ( Ferrer, M, 2011) |
| " No major cytochrome P450 inhibition has been reported with desloratadine, fexofenadine and levocetirizine, and the bioavailability of desloratadine is minimally affected by drugs interfering with transporter molecules." | 2.44 | Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review. ( Devillier, P; Faisy, C; Roche, N, 2008) |
| "Levocetirizine is an effective and safe treatment for use in adults and children with allergic disease." | 2.44 | A review of the role of levocetirizine as an effective therapy for allergic disease. ( Walsh, GM, 2008) |
| "Levocetirizine has pharmacodynamically and pharmacokinetically favourable characteristics, including high bioavailability, rapid onset of action, limited distribution and a low degree of metabolism." | 2.43 | Levocetirizine: an update. ( Walsh, GM, 2006) |
| "Cetirizine hydrochloride is an orally-active and selective histamine (H(1))-receptor antagonist." | 2.42 | Review of cetirizine hydrochloride for the treatment of allergic disorders. ( Dinakar, C; Portnoy, JM, 2004) |
| "Cetirizine is a safe second generation antihistamine." | 2.40 | Use of cetirizine in dermatologic disorders. ( Henz, BM; Zuberbier, T, 1999) |
| " The recommended adult dosage of this agent is 5 or 10 mg/d." | 2.38 | Cetirizine: a new, nonsedating antihistamine. ( Barnes, CL; McKenzie, CA; Poinsett-Holmes, K; Webster, KD, 1993) |
| "Cetirizine is a new H1 antagonist with potent inhibitory action against the infiltration of eosinophils into involved tissue, thereby affecting the late-phase reaction." | 2.38 | Cetirizine: a new H1 antagonist with antieosinophilic activity in chronic urticaria. ( Townley, RG, 1991) |
| " In cases of failure, treatment was switched to omalizumab at doses of < 300 mg/month with incremental dosage increases as necessary (monthly dose range, 150-600 mg/month)." | 1.51 | Real-life experience in the treatment of solar urticaria: retrospective cohort study. ( Enk, CD; Hodak, E; Lapidoth, M; Levi, A; Mazor, S; Snast, I; Uvaidov, V, 2019) |
| "Aquagenic urticaria is a rare form of contact urticaria with small wheals generally affecting the upper part of the body." | 1.40 | [Aquagenic urticaria. A case report]. ( Kreft, B; Marsch, WC; Wohlrab, J, 2014) |
| " The first-generation H(1)-antihistamines are associated with marked adverse effects such as sedation, sleepiness/drowsiness as well as difficulties in learning and cognitive processing; thus, they are recommended for limited or discontinued use in children with AR or CIU." | 1.37 | Evidence for clinical safety, efficacy, and parent and physician perceptions of levocetirizine for the treatment of children with allergic disease. ( Kurzawa, R; Pampura, AN; Papadopoulos, NG; Spičák, V, 2011) |
| "Recently, several authors have suggested an off-label increase of antihistamine dosage should be given to patients with chronic urticaria (CU) not responding to the usual, recommended doses, in order to gain better control of the disease." | 1.34 | Chronic unremitting urticaria: is the use of antihistamines above the licensed dose effective? A preliminary study of cetirizine at licensed and above-licensed doses. ( Asero, R, 2007) |
| " It is concluded that estimating in vivo receptor occupancy, which takes into account both the affinity of the drug for the receptor and its free plasma concentration, is a far better predictor for human pharmacodynamics and hence antihistamine potency, than considering in vitro affinity and plasmatic half-life only." | 1.33 | Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines. ( Baltes, E; Benedetti, MS; Chatelain, P; Gillard, M, 2005) |
| "Acquired cold urticaria is an infrequent physical urticaria that can provoke severe systemic reactions." | 1.32 | Treatment of acquired cold urticaria with cetirizine and zafirlukast in combination. ( Bonadonna, P; Canonica, GW; Lombardi, C; Passalacqua, G; Senna, G, 2003) |
| "Familial cold urticaria is a rare, autosomally dominant disease of interest to physicians treating urticarial-type diseases." | 1.29 | Familial cold urticaria: a father and daughter with typical clinical and laboratory features. ( Armenaka, M; Kalogeromitros, D; Katsarou, A; Polizou, E; Stratigos, I; Zografakis, I, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.78) | 18.7374 |
| 1990's | 47 (26.11) | 18.2507 |
| 2000's | 72 (40.00) | 29.6817 |
| 2010's | 45 (25.00) | 24.3611 |
| 2020's | 11 (6.11) | 2.80 |
| Authors | Studies |
|---|---|
| Cook, JS | 1 |
| Angles, A | 1 |
| Morley, E | 1 |
| Blaiss, MS | 2 |
| Bernstein, JA | 2 |
| Kessler, A | 2 |
| Pines, JM | 1 |
| Camargo, CA | 1 |
| Fulgham, P | 1 |
| Haumschild, R | 1 |
| Rupp, K | 1 |
| Tyler, T | 1 |
| Moellman, J | 1 |
| Javaud, N | 1 |
| Soria, A | 1 |
| Maignan, M | 1 |
| Martin, L | 1 |
| Descamps, V | 1 |
| Fain, O | 1 |
| Bouillet, L | 1 |
| Berard, F | 1 |
| Tazarourte, K | 1 |
| Roy, PM | 1 |
| Fontaine, JP | 1 |
| Bagot, M | 1 |
| Khellaf, M | 1 |
| Goulet, H | 1 |
| Lapostolle, F | 1 |
| Casalino, E | 1 |
| Doutre, MS | 1 |
| Gil-Jardine, C | 1 |
| Caux, F | 1 |
| Chosidow, O | 1 |
| Pateron, D | 1 |
| Vicaut, E | 1 |
| Adnet, F | 1 |
| Bianchi, L | 1 |
| Hansel, K | 1 |
| Tramontana, M | 1 |
| Principato, M | 1 |
| Moretta, I | 1 |
| Principato, S | 1 |
| Stingeni, L | 1 |
| Podder, I | 1 |
| Das, A | 1 |
| Ghosh, S | 1 |
| Biswas, D | 1 |
| Sengupta, S | 1 |
| Chowdhury, SN | 1 |
| Abella, BS | 1 |
| Berger, WE | 1 |
| Stiell, IG | 1 |
| Herres, JP | 1 |
| Moellman, JJ | 1 |
| Suner, S | 1 |
| Klausner, HA | 1 |
| Caterino, JM | 1 |
| Du, J | 1 |
| Wilkerson, H | 1 |
| Datta, P | 1 |
| Rewers-Felkins, K | 1 |
| Baker, T | 1 |
| Hale, TW | 1 |
| Hussain, S | 1 |
| Aziz, SG | 1 |
| Shah, B | 1 |
| De, A | 1 |
| Sarda, A | 1 |
| Kochhar, AM | 1 |
| Dhoot, D | 1 |
| Deshmukh, G | 1 |
| Barkate, H | 1 |
| Veraldi, S | 1 |
| Romagnuolo, M | 1 |
| Benzecry, V | 1 |
| Bethea, LH | 1 |
| Tuano, KS | 1 |
| Seth, N | 1 |
| Chinen, J | 1 |
| Barniol, C | 1 |
| Dehours, E | 1 |
| Mallet, J | 1 |
| Houze-Cerfon, CH | 1 |
| Lauque, D | 1 |
| Charpentier, S | 1 |
| Kolkhir, P | 1 |
| Pogorelov, D | 1 |
| Olisova, O | 1 |
| Iweala, OI | 1 |
| Copenhaver, C | 1 |
| Wu, EY | 1 |
| Moran, TP | 1 |
| Pandey, S | 1 |
| Sinha, RJ | 1 |
| Sharma, D | 1 |
| Singh, V | 1 |
| Snast, I | 1 |
| Lapidoth, M | 1 |
| Uvaidov, V | 1 |
| Enk, CD | 2 |
| Mazor, S | 1 |
| Hodak, E | 1 |
| Levi, A | 2 |
| Hassoun, Y | 1 |
| Stevenson, MR | 1 |
| Bernstein, DI | 1 |
| Bulca, S | 1 |
| Bayramgürler, D | 2 |
| Odyakmaz Demirsoy, E | 1 |
| Yavuz, M | 1 |
| Sikar Aktürk, A | 1 |
| Bilen, N | 2 |
| Kıran, R | 1 |
| Yan, M | 1 |
| Ye, F | 1 |
| Zhang, Y | 2 |
| Cai, X | 1 |
| Fu, Y | 1 |
| Yang, X | 1 |
| Tanizaki, H | 1 |
| Nakamizo, S | 1 |
| Nakahigashi, K | 1 |
| Miyachi, Y | 1 |
| Kabashima, K | 1 |
| Kreft, B | 1 |
| Wohlrab, J | 1 |
| Marsch, WC | 3 |
| Dakhale, GN | 1 |
| Shinde, AT | 1 |
| Mahatme, MS | 1 |
| Hiware, SK | 1 |
| Mishra, DB | 1 |
| Mukhi, JI | 1 |
| Salve, AM | 1 |
| Staevska, M | 2 |
| Gugutkova, M | 1 |
| Lazarova, C | 2 |
| Kralimarkova, T | 2 |
| Dimitrov, V | 3 |
| Zuberbier, T | 5 |
| Church, MK | 7 |
| Popov, TA | 3 |
| Rorie, A | 1 |
| Goldner, WS | 1 |
| Lyden, E | 1 |
| Poole, JA | 1 |
| Plichta, D | 1 |
| Spiewak, R | 1 |
| Nath, PI | 1 |
| Coop, CA | 1 |
| Başak, PY | 1 |
| Vural, H | 1 |
| Kazanoglu, OO | 1 |
| Erturan, I | 1 |
| Buyukbayram, HI | 1 |
| Sharma, M | 1 |
| Bennett, C | 1 |
| Cohen, SN | 1 |
| Carter, B | 1 |
| Johnson, M | 1 |
| Kwatra, G | 1 |
| Badyal, DK | 1 |
| Thomas, EA | 1 |
| Guevara-Gutierrez, E | 1 |
| Bonilla-Lopez, S | 1 |
| Hernández-Arana, S | 1 |
| Tlacuilo-Parra, A | 1 |
| Kepley, JM | 1 |
| Bowen, C | 1 |
| Kobayashi, T | 1 |
| Sharma, VK | 1 |
| Gupta, V | 1 |
| Pathak, M | 1 |
| Ramam, M | 1 |
| Snidvongs, K | 1 |
| Seresirikachorn, K | 1 |
| Khattiyawittayakun, L | 1 |
| Chitsuthipakorn, W | 1 |
| Jin, CY | 1 |
| Wang, DL | 1 |
| Fang, ZD | 1 |
| Izumi, N | 1 |
| Mizuguchi, H | 1 |
| Umehara, H | 1 |
| Ogino, S | 1 |
| Fukui, H | 1 |
| Sugiura, K | 1 |
| Hirai, S | 1 |
| Suzuki, T | 1 |
| Usuda, T | 1 |
| Kondo, T | 1 |
| Azumi, T | 1 |
| Masaki, S | 1 |
| Yokoi, T | 1 |
| Nitta, Y | 1 |
| Kamiya, S | 1 |
| Ando, K | 1 |
| Mori, T | 1 |
| Tomita, Y | 1 |
| Potter, PC | 1 |
| Kapp, A | 3 |
| Maurer, M | 3 |
| Guillet, G | 1 |
| Jian, AM | 1 |
| Hauptmann, P | 1 |
| Finlay, AY | 1 |
| Wan, KS | 1 |
| Ducharme, EE | 1 |
| Weinberg, JM | 1 |
| Afonso, N | 1 |
| Shetgaonkar, P | 1 |
| Dang, A | 1 |
| Rataboli, PV | 1 |
| Singh-Franco, D | 1 |
| Ghin, HL | 1 |
| Robles, GI | 1 |
| Borja-Hart, N | 1 |
| Perez, A | 1 |
| Oanta, A | 1 |
| Bogacka, E | 1 |
| Medina, I | 1 |
| Wesel, F | 1 |
| Uhl, P | 1 |
| Antépara, I | 1 |
| Jáuregui, I | 1 |
| Valiente, R | 1 |
| Shi, LH | 1 |
| Fang, CY | 1 |
| Li, XM | 1 |
| Asero, R | 3 |
| Tedeschi, A | 1 |
| Cugno, M | 1 |
| Kraeva, S | 1 |
| Popova, D | 1 |
| Church, DS | 1 |
| Long, JW | 1 |
| Wang, YY | 1 |
| Pi, XM | 1 |
| Tu, YT | 1 |
| Hong, JB | 2 |
| Lee, HC | 2 |
| Hu, FC | 1 |
| Chu, CY | 2 |
| Pampura, AN | 1 |
| Papadopoulos, NG | 1 |
| Spičák, V | 1 |
| Kurzawa, R | 1 |
| Bobadilla-González, P | 1 |
| Pérez-Rangel, I | 1 |
| Cámara-Hijón, C | 1 |
| García-Menaya, JM | 1 |
| Sánchez-Vega, S | 1 |
| Arias-Santiago, S | 1 |
| Girón-Prieto, MS | 1 |
| Martinez-Peinado, C | 1 |
| Gutiérrez-Salmerón, MT | 1 |
| Naranjo-Sintes, R | 1 |
| Zhong, J | 1 |
| Xian, D | 1 |
| Xu, Y | 1 |
| Liu, J | 1 |
| Ferrer, M | 1 |
| Stewart, L | 1 |
| Nuara, A | 1 |
| Anand, D | 1 |
| Kia, K | 1 |
| Cockerell, CJ | 1 |
| Fang, SY | 1 |
| Perng, DW | 1 |
| Lee, JY | 1 |
| Lin, DY | 1 |
| Huangs, CY | 1 |
| Okubo, Y | 1 |
| Shigoka, Y | 1 |
| Yamazaki, M | 1 |
| Tsuboi, R | 1 |
| Maiti, R | 1 |
| Jaida, J | 1 |
| Raghavendra, BN | 1 |
| Goud, P | 1 |
| Ahmed, I | 1 |
| Palani, A | 1 |
| Carter, NJ | 1 |
| Schoepke, N | 1 |
| Sil, A | 1 |
| Tripathi, SK | 1 |
| Chaudhuri, A | 1 |
| Das, NK | 1 |
| Hazra, A | 1 |
| Bagchi, C | 1 |
| Islam, CN | 1 |
| Tella, R | 1 |
| Gaig, P | 1 |
| Bartra, J | 1 |
| Garcia-Ortega, P | 1 |
| Scheindlin, S | 1 |
| Nordness, M | 1 |
| Zacharisen, MC | 1 |
| Duchateau, J | 1 |
| Heenen, M | 1 |
| Sternon, J | 1 |
| Ohtani, T | 1 |
| Aiba, S | 1 |
| Mizuashi, M | 1 |
| Kawamoto, Y | 1 |
| Tagami, H | 1 |
| Purohit, A | 5 |
| Melac, M | 3 |
| Pauli, G | 5 |
| Frossard, N | 5 |
| Bonadonna, P | 1 |
| Lombardi, C | 2 |
| Senna, G | 1 |
| Canonica, GW | 2 |
| Passalacqua, G | 2 |
| Portnoy, JM | 1 |
| Dinakar, C | 1 |
| Bagenstose, SE | 1 |
| Levin, L | 1 |
| Handa, S | 1 |
| Dogra, S | 1 |
| Kumar, B | 1 |
| Bloebaum, RM | 1 |
| Grant, JA | 3 |
| Roongapinun, S | 1 |
| Wajajamreon, S | 1 |
| Fooanant, S | 1 |
| N'Gom, AS | 1 |
| Deslandes, B | 1 |
| Kränke, B | 1 |
| Mayr-Kanhäuser, S | 1 |
| Cranswick, N | 1 |
| Turzíkova, J | 1 |
| Fuchs, M | 1 |
| Hulhoven, R | 1 |
| Dhar, S | 1 |
| Varghese, ST | 1 |
| Georges, G | 1 |
| Mahajan, VK | 1 |
| Sharma, NL | 1 |
| Sharma, VC | 1 |
| Chang, YC | 1 |
| George, SJ | 1 |
| Hsu, S | 1 |
| Gillard, M | 1 |
| Benedetti, MS | 1 |
| Chatelain, P | 1 |
| Baltes, E | 1 |
| Pitarch, G | 1 |
| Torrijos, A | 1 |
| Martínez-Menchón, T | 1 |
| Sánchez-Carazo, JL | 1 |
| Fortea, JM | 1 |
| Nettis, E | 1 |
| Colanardi, MC | 1 |
| Barra, L | 1 |
| Ferrannini, A | 1 |
| Vacca, A | 1 |
| Tursi, A | 1 |
| Kalogeromitros, D | 3 |
| Kempuraj, D | 1 |
| Katsarou-Katsari, A | 1 |
| Makris, M | 2 |
| Gregoriou, S | 2 |
| Papaliodis, D | 1 |
| Theoharides, TC | 2 |
| Pfaar, O | 1 |
| Wrede, H | 1 |
| Barth, C | 1 |
| Hansen, I | 1 |
| Klimek, L | 1 |
| Pichler, WJ | 2 |
| Dumitrascu, D | 1 |
| Bachvarova, A | 1 |
| Bocsan, C | 1 |
| Walsh, GM | 2 |
| Caproni, M | 1 |
| Volpi, W | 1 |
| Giomi, B | 1 |
| Torchia, D | 1 |
| Del Bianco, E | 1 |
| Fabbri, P | 1 |
| Demarteau, N | 1 |
| Nuutinen, P | 1 |
| Harvima, IT | 1 |
| Ackermann, L | 1 |
| Kłos, K | 2 |
| Kruszewski, J | 2 |
| Kruszewski, R | 1 |
| Sułek, K | 2 |
| Garg, G | 1 |
| Thami, GP | 1 |
| Chang, YS | 1 |
| Kwon, HS | 1 |
| Cho, SH | 1 |
| Kim, YY | 1 |
| Min, KU | 1 |
| Simons, FE | 7 |
| Young, D | 1 |
| Kameyoshi, Y | 1 |
| Tanaka, T | 1 |
| Mihara, S | 1 |
| Takahagi, S | 1 |
| Niimi, N | 1 |
| Hide, M | 1 |
| Papageorgiou, C | 1 |
| Chatziantonakis, N | 1 |
| Spanoudaki, N | 1 |
| Rabavilas, A | 1 |
| Rigopoulos, D | 1 |
| Strolin-Benedetti, M | 1 |
| Takahashi, H | 1 |
| Morita, E | 1 |
| Devillier, P | 1 |
| Roche, N | 1 |
| Faisy, C | 1 |
| De Vos, C | 2 |
| Mitchev, K | 1 |
| Pinelli, ME | 1 |
| Derde, MP | 1 |
| Boev, R | 1 |
| Engin, B | 1 |
| Ozdemir, M | 1 |
| Balevi, A | 1 |
| Mevlitoğlu, I | 1 |
| Aberer, W | 1 |
| Burtin, B | 3 |
| Rihoux, JP | 7 |
| Czarnetzki, BM | 1 |
| Breneman, D | 2 |
| Bronsky, EA | 1 |
| Bruce, S | 2 |
| Kalivas, JT | 1 |
| Klein, GL | 1 |
| Roth, HL | 1 |
| Tharp, MD | 2 |
| Treger, C | 1 |
| Soter, N | 1 |
| Broide, D | 1 |
| Katsarou, A | 1 |
| Armenaka, M | 1 |
| Polizou, E | 1 |
| Zografakis, I | 1 |
| Stratigos, I | 1 |
| Sussman, GL | 1 |
| Simons, KJ | 3 |
| Androsov, VN | 1 |
| Belostotskaia, OI | 1 |
| Il'ina, NI | 1 |
| Goldsmith, P | 1 |
| Dowd, PM | 1 |
| Sharpe, GR | 2 |
| Shuster, S | 2 |
| Tadmor, B | 1 |
| Rubinow, A | 1 |
| Shalit, M | 1 |
| Lambert, D | 1 |
| Hantzperg, M | 1 |
| Danglas, P | 1 |
| Bloom, M | 2 |
| Andri, L | 1 |
| Senna, GE | 1 |
| Betteli, C | 1 |
| Givanni, S | 1 |
| Andri, G | 1 |
| Mezzelani, P | 1 |
| Barnes, CL | 1 |
| McKenzie, CA | 1 |
| Webster, KD | 1 |
| Poinsett-Holmes, K | 1 |
| von Schulthess, A | 1 |
| Breneman, DL | 1 |
| Münzberger, C | 1 |
| Haustein, U | 1 |
| Trippas, E | 1 |
| Mariz, SD | 1 |
| Henz, BM | 2 |
| Donnelly, F | 1 |
| Groschner, K | 1 |
| Pöch, G | 1 |
| Karamfilov, T | 1 |
| Wilmer, A | 1 |
| Hipler, UC | 1 |
| Wollina, U | 1 |
| Danielson, L | 1 |
| DeVos, C | 2 |
| Apaydýn, R | 1 |
| Altintaş, L | 1 |
| Sal, G | 1 |
| Dökmeci, S | 1 |
| Utkan, T | 1 |
| Rewari, S | 1 |
| Gupta, U | 1 |
| Uchida, M | 1 |
| Nakahara, H | 1 |
| Johnston, L | 1 |
| Monfrecola, G | 1 |
| Masturzo, E | 1 |
| Riccardo, AM | 1 |
| Del Sorbo, A | 1 |
| Calista, D | 1 |
| Schianchi, S | 1 |
| Morri, M | 1 |
| Fujii, K | 1 |
| Konishi, K | 1 |
| Kanno, Y | 1 |
| Ohgou, N | 1 |
| Parsad, D | 1 |
| Pandhi, R | 1 |
| Juneja, A | 1 |
| La Rosa, M | 1 |
| Leonardi, S | 1 |
| Marchese, G | 1 |
| Corrias, A | 1 |
| Barberio, G | 1 |
| Oggiano, N | 1 |
| Grimaldi, I | 1 |
| Clough, GF | 1 |
| Boutsiouki, P | 1 |
| Pacor, ML | 1 |
| Di Lorenzo, G | 1 |
| Corrocher, R | 1 |
| Riethuisen, JM | 1 |
| Moulaert, B | 1 |
| Schröter, S | 1 |
| Damveld, B | 1 |
| Siergiejko, Z | 1 |
| Michalska, I | 1 |
| Rogalewska, A | 1 |
| Chyrek-Borowska, S | 1 |
| Townley, RG | 2 |
| Okada, C | 1 |
| Soter, NA | 1 |
| Kontou-Fili, K | 3 |
| Maniatakou, G | 3 |
| Demaka, P | 2 |
| Gonianakis, M | 2 |
| Palaiologos, G | 1 |
| Aroni, K | 2 |
| Goh, CL | 1 |
| Wong, WK | 1 |
| Lim, J | 1 |
| Bilsland, D | 1 |
| Ferguson, J | 1 |
| Juhlin, L | 4 |
| McMillan, JL | 1 |
| Lobaton, P | 1 |
| Moreno, F | 1 |
| Coulie, P | 1 |
| Kietzmann, H | 1 |
| Macher, E | 1 |
| Ghys, L | 1 |
| Paleologos, G | 2 |
| Kalivas, J | 1 |
| Tharp, M | 1 |
| Bigby, M | 1 |
| Campoli-Richards, DM | 1 |
| Buckley, MM | 1 |
| Fitton, A | 1 |
| Billardon, M | 1 |
| Arendt, C | 1 |
| Pechadre, JC | 1 |
| Vernay, D | 1 |
| Trolese, JF | 1 |
| Dupont, P | 1 |
| Müller, FO | 1 |
| Botha, JJ | 1 |
| van Dyk, M | 1 |
| Luus, HG | 1 |
| Groenewoud, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| COrticosteroids in acUte uRticAria in emerGency dEpartment[NCT03545464] | Phase 3 | 240 participants (Anticipated) | Interventional | 2019-09-21 | Recruiting | ||
| A Phase III, Multi-center, Double Blind, Randomized, Active Controlled Clinical Trial to Evaluate the Non-Inferiority Comparing Cetirizine Injection 10 mg to Diphenhydramine Injection, 50 mg, for the Treatment of Acute Urticaria[NCT02935699] | Phase 3 | 262 participants (Actual) | Interventional | 2017-03-01 | Completed | ||
| Glucocorticoids Associated With Antihistamines Versus Antihistamines Randomized Double Blinded for the Management of Acute Urticaria in Emergency[NCT02565680] | Phase 2/Phase 3 | 100 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| Observational Study of the Prevalence of Antihistamine Responsive Gastrointestinal Symptoms in Patients Diagnosed With Irritable Bowel Syndrome With Diarrhea[NCT04612803] | 100 participants (Anticipated) | Observational | 2020-11-15 | Not yet recruiting | |||
| The Role of Vitamin D in Chronic Urticaria and Angioedema Treatment[NCT01371877] | 42 participants (Actual) | Interventional | 2011-11-01 | Completed | |||
| Double-blind, Randomised, Placebo-controlled, Phase III Study Comparing the Efficacy and Safety of Bilastine 20 mg Once Daily and Levocetirizine 5 mg for the Treatment of Chronic Idiopathic Urticaria[NCT00421109] | Phase 3 | 522 participants (Actual) | Interventional | 2006-07-31 | Completed | ||
| A Multicentre, International, Adaptive, Open-label, Repeated Administration Pharmacokinetic Study of Bilastine in Children From 2 to <12 Years of Age With Allergic Rhinoconjunctivitis or Chronic Urticaria[NCT01081574] | Phase 1/Phase 2 | 36 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| Efficacy and Safety of 20 mg Levocetirizine and 15 mg Levocetirizine + 50 mg Bed-Time Hydroxyzine in Severe Chronic Urticaria in Adults: a Pilot, Randomized, Double-blind, Cross-over and Parallel, Active-controlled, Single-centre Study[NCT01250652] | Phase 4 | 24 participants (Actual) | Interventional | 2011-03-31 | Completed | ||
| Quality of Life in Patients With Allergic Rhinitis: a Clinical Trial Comparing the Use of Bilastine Versus Loratadine[NCT02513290] | Phase 4 | 73 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| Comparison of Efficacy and Consistency of Action of Levocetirizine 5 mg Once Daily With Fexofenadine 60 mg Twice Daily in the Histamine Induced Wheal, Flare and Itch Response[NCT01586091] | Phase 4 | 18 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| The Efficacy and Safety of Levocetirizine Dihydrochloride Oral Drops Given 0.125 mg/kg b.i.d. During 90 Days in the Treatment of Recurrent Cough Associated With Other Allergic Symptoms, e.g. Wheezing, in Children Aged 1-2 Years.[NCT00520754] | Phase 2 | 15 participants (Actual) | Interventional | 2001-12-31 | Completed | ||
| Multicenter Randomized, Double-blind, Placebo-controlled Parallel Clinical Trial to Assess Efficacy and Safety of Omalizumab (Xolair®) in a New Indication: Cholinergic Urticarial[NCT02012387] | Phase 2 | 24 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Adaptative Servoventilation Compliance in Left Ventricular Dysfunction Patients With Central Sleep Apnea: Benefit of One Month Hypnotic (Zopiclone) Versus Placebo[NCT02820441] | Phase 4 | 2 participants (Actual) | Interventional | 2016-05-31 | Terminated | ||
| [NCT02854397] | 31 participants (Actual) | Observational | 2016-02-15 | Terminated (stopped due to Recruitment difficulties) | |||
| A Placebo Controlled Trial to Evaluate The Effects of Levocetirizine on Nasal Allergen Challenge And Adenosine Monophosphate Challenge In Patients With Intermittent and Persistent Allergic Rhinitis[NCT00679250] | Phase 4 | 25 participants (Actual) | Interventional | 2005-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Change from baseline to 2 hours in patient-rated pruritus Severity score (values at 2 hours minus Baseline)~Patient Pruritus Severity Score Ask the patient How severely are your hives itching at the moment? 0 = none~= mild (minimal awareness, easily tolerated)~= moderate (definite awareness, quite bothersome)~= severe (difficult to tolerate)" (NCT02935699)
Timeframe: 2 hr
| Intervention | score on a scale (Mean) |
|---|---|
| Test Drug | -1.61 |
| Control | -1.50 |
Number of patients who needed to return to treatment center approximately 24 hours after discharge (NCT02935699)
Timeframe: up to 24 hrs
| Intervention | Participants (Count of Participants) |
|---|---|
| Test Drug | 7 |
| Control | 19 |
"Patient Sedation Score at 2 hours~Ask the patient How drowsy do you feel at the moment? 0 = None (Not drowsy at all)~= Mild (Slightly drowsy)~= Moderate (Quite drowsy)~= Severe (Extremely drowsy)" (NCT02935699)
Timeframe: 2 hours
| Intervention | score on a scale (Mean) |
|---|---|
| Test Drug | 0.46 |
| Control | 0.88 |
Time spent (hours) at the treatment center (NCT02935699)
Timeframe: up to 24 hours
| Intervention | hours (Mean) |
|---|---|
| Test Drug | 1.71 |
| Control | 2.07 |
Unit of Measure is Safety and Tolerability. The number of participants with adverse events will be compared between the groups using the independent sample t-test (assuming the distribution is normal). (NCT01371877)
Timeframe: 3 month study trial
| Intervention | participants (Number) |
|---|---|
| High Dose Vitamin D | 0 |
| Low Dose Vitamin D | 0 |
The Unit of Measure is Efficacy. The primary outcome of this study is to determine if vitamin D supplementation reduces the medication usage in subjects with CUA. Thus, for the outcome of reduction in pills, at 12 weeks, subjects whose pill usage decreases by 2 or more pills per day will be classified as improved. Subjects whose pill consumption did not change or increased will be classified as unchanged. (NCT01371877)
Timeframe: 12 week intervention
| Intervention | number of pills/day (Mean) | |
|---|---|---|
| Baseline medication usage | 3 month medication usage | |
| High Dose Vitamin D | 2.8 | 2.0 |
| Low Dose Vitamin D | 4.6 | 4.9 |
The Unit of Measure is Efficacy. The Total Urticaria Severity Score (USS) ranges from 0 to 93, higher scores = worse symptoms. This secondary outcome of this study is to determine if high dose vitamin D supplementation improves the urticaria severity score (USS). The change in USS will be compared between the groups using the independent sample t-test (assuming the distribution is normal). Logistic regression and multiple linear regression will be used to adjust for possible confounders. (NCT01371877)
Timeframe: 3 month intervention
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Baseline Total Urticaria Score | 1 week Total Urticaria Score | 3 month Total Urticaria Score | |
| High Dose Vitamin D | 41.14 | 25.48 | 15.0 |
| Low Dose Vitamin D | 40.1 | 29.24 | 24.1 |
Flaire diameter was measured with a transparent ruler as the mean of the largest diameter and the diameter at right angles to this. (NCT01586091)
Timeframe: 24 hours per treatment
| Intervention | mm (Mean) |
|---|---|
| Placebo | 69.4 |
| Levocetirizin | 20.4 |
| Fexofenadine | 39.9 |
"We measured drug concentrations and various aspects of skin provocation testing such as itch intensity and wheal size. Measurements made at each time point were as followed: Pruritus was assessed every 30 s for 10 min after SPT using a visual analogue scale (VAS) score with a 0 and 100 at the two ex- tremes of an unmarked 100 mm line with higher values indicating greater puritus. The mean VAS for each 10 min was calculated and used as a primary end Point." (NCT01586091)
Timeframe: up to 10 minutes after skin prick test performed 24 hours after drug administration
| Intervention | mm (Mean) |
|---|---|
| Levocetirizin | 11.5 |
| Fexofenadine | 25.4 |
| Placebo | 46.0 |
Wheal volume was measured by a non-contact three dimensional measurement system (PRIMOS contact, GFM Messtechnik GmbH, Teltow, Germany). (NCT01586091)
Timeframe: 24 hours per treatment
| Intervention | cm3 (Mean) |
|---|---|
| Placebo | 174.6 |
| Levocetirizin | 35.2 |
| Fexofenadine | 106.3 |
26 reviews available for cetirizine and Urticaria
| Article | Year |
|---|---|
The Role of Cetirizine in the Changing Landscape of IV Antihistamines: A Narrative Review.
Topics: Administration, Intravenous; Adult; Cetirizine; Diphenhydramine; Histamine H1 Antagonists; Humans; U | 2022 |
[Pharmacotherapy of urticaria--an analysis of the discrepancies between guidelines of expert bodies, registration documents and evidence for the effectiveness of drugs].
Topics: Administration, Oral; Administration, Topical; Anti-Allergic Agents; Benzimidazoles; Cetirizine; Glu | 2013 |
H1-antihistamines for chronic spontaneous urticaria.
Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Randomized Co | 2014 |
Sedative Effects of Levocetirizine: A Systematic Review and Meta-Analysis of Randomized Controlled Studies.
Topics: Cetirizine; Humans; Hypnotics and Sedatives; Randomized Controlled Trials as Topic; Urticaria | 2017 |
Levocetirizine for chronic idiopathic urticaria: a review.
Topics: Cetirizine; Chronic Disease; Cost-Benefit Analysis; Histamine H1 Antagonists, Non-Sedating; Humans; | 2009 |
Levocetirizine for the treatment of allergic rhinitis and chronic idiopathic urticaria in adults and children.
Topics: Adult; Cetirizine; Child; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Quality | 2009 |
Pharmacokinetic evaluation of levocetirizine.
Topics: Cetirizine; Chronic Disease; Drug Evaluation; Histamine H1 Antagonists, Non-Sedating; Humans; Random | 2011 |
Bilastine: in allergic rhinitis and urticaria.
Topics: Area Under Curve; Benzimidazoles; Cetirizine; Histamine H1 Antagonists, Non-Sedating; Humans; Lorata | 2012 |
H(1)-antihistamines and urticaria: how can we predict the best drug for our patient?
Topics: Anti-Allergic Agents; Cetirizine; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratad | 2012 |
[H1 histamine antagonists].
Topics: Acetates; Anti-Allergic Agents; Cetirizine; Chemistry, Pharmaceutical; Histamine H1 Antagonists; Hum | 2003 |
Review of cetirizine hydrochloride for the treatment of allergic disorders.
Topics: Anti-Allergic Agents; Asthma; Cetirizine; Clinical Trials as Topic; Dermatitis, Atopic; Histamine H1 | 2004 |
A review of the evidence from comparative studies of levocetirizine and desloratadine for the symptoms of allergic rhinitis.
Topics: Cetirizine; Histamine Antagonists; Humans; Loratadine; Nose; Piperazines; Quality of Life; Randomize | 2005 |
Levocetirizine: an update.
Topics: Anti-Inflammatory Agents; Cetirizine; Histamine H1 Antagonists; Humans; Piperazines; Rhinitis; Urtic | 2006 |
Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.
Topics: Cetirizine; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Rhinitis, | 2008 |
A review of the role of levocetirizine as an effective therapy for allergic disease.
Topics: Adult; Anti-Inflammatory Agents; Biological Availability; Cetirizine; Child; Controlled Clinical Tri | 2008 |
Clinical studies with cetirizine in allergic rhinitis and chronic urticaria.
Topics: Cetirizine; Chronic Disease; Clinical Trials as Topic; Humans; Rhinitis, Allergic, Perennial; Rhinit | 1995 |
The new H1 antihistamines. Treatment of urticaria and other clinical problems.
Topics: Astemizole; Cetirizine; Dermatitis, Atopic; Histamine H1 Antagonists; Humans; Loratadine; Terfenadin | 1993 |
Cetirizine: a new, nonsedating antihistamine.
Topics: Asthma; Cetirizine; Humans; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Urticaria | 1993 |
[Cetirizine].
Topics: Anti-Allergic Agents; Cetirizine; Heart; Histamine H1 Antagonists; Humans; Hypersensitivity; Psychom | 1998 |
Use of cetirizine in dermatologic disorders.
Topics: Adolescent; Adult; Anti-Allergic Agents; Cetirizine; Dermatitis, Atopic; Histamine H1 Antagonists; H | 1999 |
[Pharmacological and clinical properties of cetirizine hydrochloride].
Topics: Animals; Anti-Allergic Agents; Cetirizine; Chemotaxis; Chronic Disease; Electrocardiography; Eosinop | 2000 |
Use of cetirizine to investigate non-H1 effects of second-generation antihistamines.
Topics: Cetirizine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; | 1992 |
Cetirizine: a new H1 antagonist with antieosinophilic activity in chronic urticaria.
Topics: Cetirizine; Chronic Disease; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzine; Urticaria | 1991 |
Recent advances in H1-receptor antagonist treatment.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonis | 1990 |
Cetirizine. A review of its pharmacological properties and clinical potential in allergic rhinitis, pollen-induced asthma, and chronic urticaria.
Topics: Animals; Asthma; Cetirizine; Chronic Disease; Histamine H1 Antagonists; Humans; Hydroxyzine; Pollen; | 1990 |
Three new non-sedative antihistamines: worth keeping an eye open for.
Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Rhinitis, All | 1990 |
87 trials available for cetirizine and Urticaria
| Article | Year |
|---|---|
Glucocorticoids for acute urticaria: study protocol for a double-blind non-inferiority randomised controlled trial.
Topics: Acute Disease; Adult; Cetirizine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fol | 2019 |
Effectiveness, safety, and tolerability of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic spontaneous urticaria: A double-blind, parallel group, randomized controlled trial.
Topics: Benzimidazoles; Cetirizine; Chronic Disease; Chronic Urticaria; Double-Blind Method; Histamine H1 An | 2020 |
Intravenous Cetirizine Versus Intravenous Diphenhydramine for the Treatment of Acute Urticaria: A Phase III Randomized Controlled Noninferiority Trial.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Canada; Cetirizine; Diphenh | 2020 |
Levocetirizine and Prednisone Are Not Superior to Levocetirizine Alone for the Treatment of Acute Urticaria: A Randomized Double-Blind Clinical Trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Cetirizine; Dou | 2018 |
Comparison of effects of 5 and 10 mg oral desloratadine and levocetirizine on histamine-induced wheal and flare response in healthy volunteers.
Topics: Administration, Oral; Adult; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Double-Blind Meth | 2013 |
Optimization model research on efficacy in treatment of chronic urticaria by Chinese and Western medicine based on a genetic algorithm.
Topics: Algorithms; Case-Control Studies; Cetirizine; Chronic Disease; Drugs, Chinese Herbal; Humans; Urtica | 2013 |
A double dose of levocetirizine leads to better control of histamine-induced flare, wheal and itch in healthy donors.
Topics: Adult; Cetirizine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female | 2013 |
Clinical effectiveness and safety of cetirizine versus rupatadine in chronic spontaneous urticaria: a randomized, double-blind, 6-week trial.
Topics: Adult; Cetirizine; Chronic Disease; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antago | 2014 |
Night-time sedating H1 -antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Cross-Over Studies; Double-Blind Method; Drug Administrati | 2014 |
Beneficial role for supplemental vitamin D3 treatment in chronic urticaria: a randomized study.
Topics: Acetates; Adult; Aged; Cetirizine; Cholecalciferol; Chronic Disease; Cyclopropanes; Dietary Suppleme | 2014 |
Levocetirizine and rupatadine in chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Child; Chronic Disease; Cyproheptadine; Female; Histamine H1 An | 2015 |
Safety and efficacy of cetirizine versus cetirizine plus ranitidine in chronic urticaria: Double-blind randomized placebo-controlled study.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonists, Non | 2015 |
An open-label prospective clinical study to assess the efficacy of increasing levocetirizine dose up to four times in chronic spontaneous urticaria not controlled with standard dose.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Disorders of Excessive Somnolence; Dose-Respon | 2017 |
[Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood].
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Drug Therapy, Combination; Drugs, Chinese Herbal; Fe | 2008 |
Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients.
Topics: Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Hu | 2009 |
Efficacy of leukotriene receptor antagonist with an anti-H1 receptor antagonist for treatment of chronic idiopathic urticaria.
Topics: Acetates; Adolescent; Adult; Cetirizine; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; | 2009 |
Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Area Under Curve; Benzimidazoles; Cetirizine; Chronic Disease; Double-Blind | 2010 |
Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Area Under Curve; Benzimidazoles; Cetirizine; Chronic Disease; Double-Blind | 2010 |
Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Area Under Curve; Benzimidazoles; Cetirizine; Chronic Disease; Double-Blind | 2010 |
Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Area Under Curve; Benzimidazoles; Cetirizine; Chronic Disease; Double-Blind | 2010 |
[Therapeutic effect of anti-anaphylaxis granule on chronic urticaria and its impact on serum levels of RANTES].
Topics: Adolescent; Adult; Cetirizine; Chemokine CCL11; Chemokine CCL5; Drugs, Chinese Herbal; Female; Human | 2009 |
The effectiveness of levocetirizine and desloratadine in up to 4 times conventional doses in difficult-to-treat urticaria.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Fem | 2010 |
Clinical observation on the treatment of chronic urticaria with total glucosides of paeony capsule combined with citirizine.
Topics: Adolescent; Adult; Anti-Allergic Agents; Capsules; Cetirizine; Chronic Disease; Drug Therapy, Combin | 2010 |
A randomized, double-blind, active-controlled, parallel-group pilot study to compare the efficacy and sedative effects of desloratadine 5 mg with levocetirizine 5 mg in the treatment of chronic idiopathic urticaria.
Topics: Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Hu | 2010 |
Efficacy of Tripterygium hypoglaucum Hutch in adults with chronic urticaria.
Topics: Adult; Antipruritics; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagon | 2011 |
An open-label, multicentre study of levocetirizine for the treatment of allergic rhinitis and urticaria in Taiwanese patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cetirizine; Child; Female; Histamine H1 Antagonists, Non | 2010 |
Double dose of cetirizine hydrochloride is effective for patients with urticaria resistant: a prospective, randomized, non-blinded, comparative clinical study and assessment of quality of life.
Topics: Adolescent; Adult; Anti-Allergic Agents; Cetirizine; Dibenzoxepins; Double-Blind Method; Female; His | 2013 |
Comparative inhibition by bilastine and cetirizine of histamine-induced wheal and flare responses in humans.
Topics: Adult; Anti-Allergic Agents; Benzimidazoles; Cetirizine; Cross-Over Studies; Double-Blind Method; Hi | 2011 |
Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety.
Topics: Adolescent; Adult; Cetirizine; Child; Chronic Disease; Cyproheptadine; Female; Follow-Up Studies; Hi | 2011 |
The inhibition by levocetirizine and fexofenadine of the histamine-induced wheal and flare response in healthy Caucasian and Japanese volunteers.
Topics: Adult; Asian People; Cetirizine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind | 2013 |
Olopatadine versus levocetirizine in chronic urticaria: an observer-blind, randomized, controlled trial of effectiveness and safety.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Cetirizine; Chronic Dise | 2013 |
Twenty-four-hour activity and consistency of activity of levocetirizine and desloratadine in the skin.
Topics: Adolescent; Adult; Cetirizine; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Female; Hi | 2003 |
The addition of zafirlukast to cetirizine improves the treatment of chronic urticaria in patients with positive autologous serum skin test results.
Topics: Adult; Autoantigens; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagoni | 2004 |
Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Seda | 2004 |
Levocetirizine: the allergist's arsenal grows larger.
Topics: Allergy and Immunology; Cetirizine; Chronic Disease; Clinical Trials, Phase III as Topic; Double-Bli | 2004 |
Comparative efficacy of wheal-and-flare suppression among various non-sedating antihistamines and the pharmacologic insights to their efficacy.
Topics: Adolescent; Adult; Cetirizine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; M | 2004 |
Comparative activity of cetirizine and desloratadine on histamine-induced wheal-and-flare responses during 24 hours.
Topics: Adolescent; Adult; Anti-Allergic Agents; Area Under Curve; Cetirizine; Cross-Over Studies; Female; H | 2004 |
Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction.
Topics: Adolescent; Adult; Cetirizine; Cross-Over Studies; Female; Histamine; Histamine H1 Antagonists; Huma | 2004 |
Levocetirizine in 1-2 year old children: pharmacokinetic and pharmacodynamic profile.
Topics: Age Factors; Cetirizine; Cough; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Infant; Male | 2005 |
Levocetirizine in the treatment of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Female; | 2006 |
Theophylline as 'add-on' therapy to cetirizine in patients with chronic idiopathic urticaria. A randomized, double-blind, placebo-controlled pilot study.
Topics: Adolescent; Adult; Cetirizine; Double-Blind Method; Drug Therapy, Combination; Female; Histamine H1 | 2006 |
Levocetirizine in patients with chronic idiopathic urticaria: results of a multicenter clinical practice study.
Topics: Adult; Cetirizine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Pipera | 2006 |
Levocetirizine is an effective treatment in patients suffering from chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled, parallel, multicenter study.
Topics: Adult; Cetirizine; Chronic Disease; Double-Blind Method; Efficiency; Female; Germany; Histamine H1 A | 2006 |
A comparison of levocetirizine and desloratadine in the histamine-induced wheal and flare response in human skin in vivo.
Topics: Adult; Cetirizine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Histam | 2006 |
[The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].
Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Drug Administration Schedule; Histamin | 2006 |
[Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].
Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists, N | 2006 |
Comparative efficacy of cetirizine and levocetirizine in chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists, Non-Sedating | 2007 |
Safety of levocetirizine treatment in young atopic children: An 18-month study.
Topics: Asthma; Australia; Cetirizine; Dermatitis, Atopic; Double-Blind Method; Europe; Female; Histamine H1 | 2007 |
Increasing the dose of cetirizine may lead to better control of chronic idiopathic urticaria: an open study of 21 patients.
Topics: Adult; Cetirizine; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; | 2007 |
H1-antihistamine treatment in young atopic children: effect on urticaria.
Topics: Cetirizine; Child, Preschool; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; H | 2007 |
Inhibition of allergen-induced wheal and flare reactions by levocetirizine and desloratadine.
Topics: Adolescent; Adult; Allergens; Cetirizine; Cholinergic Antagonists; Cross-Over Studies; Double-Blind | 2008 |
Evaluation of the antihistamine effects of olopatadine, cetirizine and fexofenadine during a 24 h period: a double-blind, randomized, crossover, placebo-controlled comparison in skin responses induced by histamine iontophoresis.
Topics: Adult; Cetirizine; Cross-Over Studies; Dibenzoxepins; Dose-Response Relationship, Drug; Double-Blind | 2008 |
Treatment of chronic urticaria with narrowband ultraviolet B phototherapy: a randomized controlled trial.
Topics: Adult; Cetirizine; Chronic Disease; Combined Modality Therapy; Female; Histamine H1 Antagonists, Non | 2008 |
Efficacy of cetirizine in cholinergic urticaria.
Topics: Adult; Analysis of Variance; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Humans; Ma | 1995 |
Cetirizine and astemizole therapy for chronic idiopathic urticaria: a double-blind, placebo-controlled, comparative trial.
Topics: Adult; Astemizole; Cetirizine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Ma | 1995 |
Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Cimetidine; Double-Blind Method; Drug Combinat | 1995 |
[The efficacy of the Zirtek (cetirizine) preparation in chronic recurrent urticaria and seasonal allergic rhinitis].
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Drug Therapy, Combination; Female; Humans; Male; Mid | 1994 |
The effect of cetirizine on symptoms and wealing in dermographic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Double-Blind Method; Female; Humans; Male; Middle Aged; Skin; U | 1993 |
In dermographic urticaria H2 receptor antagonists have a small but therapeutically irrelevant additional effect compared with H1 antagonists alone.
Topics: Adolescent; Adult; Aged; Cetirizine; Double-Blind Method; Female; Humans; Male; Middle Aged; Ranitid | 1993 |
[Double-blind comparative study of terfenadine and cetirizine in chronic idiopathic urticaria].
Topics: Adolescent; Adult; Cetirizine; Child; Chronic Disease; Double-Blind Method; Female; Humans; Male; Mi | 1993 |
A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria.
Topics: Adult; Cetirizine; Chronic Disease; Double-Blind Method; Humans; Terfenadine; Urticaria | 1993 |
Cetirizine: a new therapeutic alternative for chronic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Male | 1996 |
Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria.
Topics: Adult; Cetirizine; Chronic Disease; Double-Blind Method; Drug Tolerance; Female; Humans; Hydroxyzine | 1996 |
Double-blind crossover study of high-dose cetirizine in cholinergic urticaria.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Cholinergic Agents; Cross-Over Studies; D | 1996 |
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamin | 1999 |
Effects of acrivastine, loratadine and cetirizine on histamine-induced wheal and flare responses.
Topics: Adult; Cetirizine; Cross-Over Studies; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadi | 1999 |
Modification of antihistaminic activity of cetirizine by nimesulide.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cetirizine; Cross-Over Studies; Double-Blind Method; | 1999 |
Clinical pharmacology of the H1-receptor antagonists cetirizine and loratadine in children.
Topics: Anti-Allergic Agents; Cetirizine; Child; Cross-Over Studies; Double-Blind Method; Histamine H1 Antag | 2000 |
Cetirizine for solar urticaria in the visible spectrum.
Topics: Adolescent; Adult; Anti-Allergic Agents; Cetirizine; Dose-Response Relationship, Radiation; Female; | 2000 |
Prevention of acute urticaria in young children with atopic dermatitis.
Topics: Acute Disease; Cetirizine; Child, Preschool; Dermatitis, Atopic; Double-Blind Method; Histamine H1 A | 2001 |
Stanozolol in chronic urticaria: a double blind, placebo controlled trial.
Topics: Adolescent; Adult; Anabolic Agents; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histam | 2001 |
Double-blind multicenter study on the efficacy and tolerability of cetirizine compared with oxatomide in chronic idiopathic urticaria in preschool children.
Topics: Anti-Allergic Agents; Cetirizine; Child, Preschool; Chronic Disease; Double-Blind Method; Drug Toler | 2001 |
Comparison of the effects of levocetirizine and loratadine on histamine-induced wheal, flare, and itch in human skin.
Topics: Anti-Allergic Agents; Cetirizine; Double-Blind Method; Histamine; Humans; Hypersensitivity, Immediat | 2001 |
Efficacy of leukotriene receptor antagonist in chronic urticaria. A double-blind, placebo-controlled comparison of treatment with montelukast and cetirizine in patients with chronic urticaria with intolerance to food additive and/or acetylsalicylic acid.
Topics: Acetates; Adolescent; Adult; Aged; Aspirin; Cetirizine; Chronic Disease; Cyclopropanes; Double-Blind | 2001 |
A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.
Topics: Adult; Benzimidazoles; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamin | 2002 |
Comparative activity of cetirizine and mizolastine on histamine-induced skin wheal and flare responses at 24 h.
Topics: Adolescent; Adult; Benzimidazoles; Cetirizine; Cross-Over Studies; Dermatitis, Allergic Contact; Dou | 2002 |
Therapeutic effects of cetirizine in delayed pressure urticaria: clinicopathologic findings.
Topics: Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; | 1991 |
Cetirizine vs placebo in chronic idiopathic urticaria--a double blind randomised cross-over study.
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonist | 1991 |
A comparison of cetirizine and terfenadine in the management of solar urticaria.
Topics: Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; | 1991 |
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadin | 1990 |
Comparison of cetirizine with astemizole in the treatment of perennial allergic rhinitis and study of the concomitant effect on histamine and allergen-induced wheal responses.
Topics: Adult; Astemizole; Benzimidazoles; Cetirizine; Double-Blind Method; Histamine H1 Antagonists; Humans | 1990 |
Comparison of cetirizine and terfenadine in the treatment of chronic idiopathic urticaria.
Topics: Benzhydryl Compounds; Cetirizine; Chronic Disease; Double-Blind Method; Histamine H1 Antagonists; Hu | 1990 |
Therapeutic effects of cetirizine in delayed pressure urticaria. Part 1. Effects on weight tests and skin-window cytology.
Topics: Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; | 1990 |
Cetirizine inhibits delayed pressure urticaria. Part 2. Skin biopsy findings.
Topics: Adult; Aged; Biopsy; Blood Cell Count; Cetirizine; Complement System Proteins; Female; Fibrin; Fluor | 1990 |
Urticaria: clinical efficacy of cetirizine in comparison with hydroxyzine and placebo.
Topics: Adolescent; Adult; Cetirizine; Child; Histamine H1 Antagonists; Humans; Hydroxyzine; Middle Aged; Ur | 1990 |
[Importance of Zyrtec in the treatment of chronic urticaria and allergic rhinopathies apropos of 1168 cases seen by hospital practitioners].
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Hydroxyzin | 1989 |
Treatment of chronic urticaria with cetirizine dihydrochloride a non-sedating antihistamine.
Topics: Adolescent; Adult; Aged; Cetirizine; Clinical Trials as Topic; Double-Blind Method; Female; Histamin | 1988 |
Comparison of the central and peripheral effects of cetirizine and terfenadine.
Topics: Adult; Benzhydryl Compounds; Cetirizine; Electroencephalography; Histamine; Histamine H1 Antagonists | 1988 |
Inhibiting effect of cetirizine on histamine-induced and 48/80-induced wheals and flares, experimental dermographism, and cold-induced urticaria.
Topics: Adult; Cetirizine; Chemical Phenomena; Chemistry; Cold Temperature; Female; Histamine Antagonists; H | 1987 |
Attenuation of cutaneous reactivity to histamine by cetirizine and dexchlorpheniramine.
Topics: Adult; Cetirizine; Chlorpheniramine; Delayed-Action Preparations; Double-Blind Method; Fatigue; Fema | 1988 |
67 other studies available for cetirizine and Urticaria
| Article | Year |
|---|---|
Urticaria and edema in a 2-year-old boy.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cetirizine; Child, Preschool; Diagnosi | 2021 |
Occupational papular urticaria due to Pyemotes ventricosus in antique dealers.
Topics: Aged; Animals; Anti-Allergic Agents; Cetirizine; Dermatitis, Allergic Contact; Dermatitis, Occupatio | 2020 |
Intravenous Cetirizine (Quzyttir) for Acute Urticaria.
Topics: Acute Disease; Administration, Intravenous; Anti-Allergic Agents; Cetirizine; Humans; Urticaria | 2020 |
Maternal Transfer of Cetirizine Into Human Milk.
Topics: Breast Feeding; Cetirizine; Family; Female; Humans; Milk, Human; Urticaria | 2021 |
A case report of sleep terrors exacerbated by cetirizine.
Topics: Adult; Cetirizine; Humans; Male; Night Terrors; Parasomnias; Rhinitis, Allergic; United States; Urti | 2021 |
Effect of bilastine on chronic spontaneous urticaria refractory to levocetrizine: Real world experience in India.
Topics: Benzimidazoles; Cetirizine; Chronic Disease; Chronic Urticaria; Humans; India; Piperidines; Urticari | 2021 |
Urticaria as a first clinical manifestation of COVID-19.
Topics: Acetaminophen; Adult; Antiviral Agents; Cetirizine; COVID-19; COVID-19 Drug Treatment; Dermatologic | 2020 |
Hereditary alpha tryptasemia in identical twins.
Topics: Adolescent; Anaphylaxis; Anti-Allergic Agents; Cetirizine; Environment; Genetic Predisposition to Di | 2021 |
CRP, D-dimer, fibrinogen and ESR as predictive markers of response to standard doses of levocetirizine in patients with chronic spontaneous urticaria.
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Sedimentation; C-Reactive Protein; Cetirizine; Chronic Di | 2017 |
Hydroxychloroquine as a steroid-sparing agent in an infant with chronic urticaria.
Topics: Acetates; Anti-Inflammatory Agents; Antimalarials; Cetirizine; Chronic Disease; Cyclopropanes; Diphe | 2018 |
Delayed pressure urticaria due to non-invasive blood pressure monitoring in a previously non-atopic man.
Topics: Aged; Anti-Allergic Agents; Arm; Arterial Pressure; Blood Pressure Determination; Cetirizine; Humans | 2018 |
Real-life experience in the treatment of solar urticaria: retrospective cohort study.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Cohort Studies; Cyclopro | 2019 |
Idiopathic postprandial diarrhea responsive to antihistamines.
Topics: Adult; Angioedema; Cetirizine; Diarrhea; Famotidine; Female; Food Hypersensitivity; Histamine Antago | 2019 |
[Aquagenic urticaria. A case report].
Topics: Adult; Anti-Allergic Agents; Bandages; Cetirizine; Chronic Inducible Urticaria; Diagnosis, Different | 2014 |
Rash and a patch test result positive for cobalt in a patient with a hip replacement.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Cetirizine; Cobalt; Dapsone | 2014 |
Effects of loratadine and cetirizine on serum levels of neuropeptides in patients with chronic urticaria.
Topics: Adolescent; Adult; Calcitonin Gene-Related Peptide; Cetirizine; Chronic Disease; Female; Histamine H | 2014 |
Rash and fever in a 14-month-old girl.
Topics: Amoxicillin; Anti-Bacterial Agents; Cetirizine; Diagnosis, Differential; Drug Eruptions; Exanthema; | 2015 |
Treatment of solar urticaria using antihistamine and leukotriene receptor antagonist combinations tailored to disease severity.
Topics: Acetates; Adolescent; Adult; Cetirizine; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combi | 2015 |
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniram | 2008 |
Evaluation of cetirizine hydrochloride-based therapeutic strategy for chronic urticaria.
Topics: Adult; Aged; Aged, 80 and over; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists, Non-S | 2008 |
Cetirizine-induced anaphylaxis: a rare adverse drug reaction.
Topics: Adult; Anaphylaxis; Anti-Allergic Agents; Cetirizine; Female; Humans; Urticaria | 2009 |
Heparin and tranexamic Acid therapy may be effective in treatment-resistant chronic urticaria with elevated d-dimer: a pilot study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Cetirizine; Chr | 2010 |
Cetirizine premedication prevents acute urticaria induced by weak COX-1 inhibitors in multiple NSAID reactors.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroida | 2010 |
Evidence for clinical safety, efficacy, and parent and physician perceptions of levocetirizine for the treatment of children with allergic disease.
Topics: Adult; Anti-Allergic Agents; Attitude of Health Personnel; Cetirizine; Child; Child, Preschool; Chro | 2011 |
Positive basophil activation test result in a patient with acute urticaria induced by cetirizine and desloratadine.
Topics: Adult; Basophils; Cetirizine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Ur | 2011 |
Dermacase. Question: Can you identify this condition? Acquired cold urticaria.
Topics: Anti-Allergic Agents; Cetirizine; Child; Cold Temperature; Diagnosis, Differential; Female; Humans; | 2011 |
Chronic idiopathic urticaria in Taiwan: a clinical study of demographics, aggravating factors, laboratory findings, serum autoreactivity and treatment response.
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Loratadine | 2011 |
Perifollicular papules and hyperkeratotic plaques on the back in a blaschkoid distribution. Morphea with features of lichen sclerosus et atrophicus (LS).
Topics: Adult; Anti-Allergic Agents; Back; Biopsy; Cetirizine; Humans; Lichen Sclerosus et Atrophicus; Male; | 2011 |
Urticaria to cetirizine.
Topics: Adult; Cetirizine; Drug Hypersensitivity; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Ur | 2002 |
Chronic urticaria and angioedema.
Topics: Angioedema; Cetirizine; Chronic Disease; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine | 2002 |
High dose cetirizine: a case report.
Topics: Anti-Allergic Agents; Arm; Back; Cetirizine; Diagnosis, Differential; Drug Administration Schedule; | 2003 |
Evaluation of the efficacy of antihistamines using human monocyte-derived dendritic cells stimulated with histamine.
Topics: Adolescent; Adult; Antigens, CD; B7-2 Antigen; Cetirizine; Chronic Disease; Cimetidine; Dendritic Ce | 2003 |
Treatment of acquired cold urticaria with cetirizine and zafirlukast in combination.
Topics: Adult; Cetirizine; Drug Therapy, Combination; Histamine H1 Antagonists, Non-Sedating; Humans; Indole | 2003 |
Levocetirizine: new preparation. Me-too: simply the active enantiomer of cetirizine.
Topics: Anti-Allergic Agents; Cetirizine; Clinical Trials as Topic; Histamine H1 Antagonists; Humans; Pipera | 2003 |
Urticarial reaction to the antihistamine levocetirizine dihydrochloride.
Topics: Adult; Cetirizine; Diagnosis, Differential; Drug Eruptions; Female; Histamine H1 Antagonists, Non-Se | 2005 |
Assessing the therapeutic benefits of antihistamines for the treatment of chronic idiopathic urticaria--a requirement for well-designed comparative clinical studies.
Topics: Cetirizine; Histamine H1 Antagonists, Non-Sedating; Humans; Terfenadine; Treatment Outcome; Urticari | 2005 |
Fixed drug eruption: a novel side-effect of levocetirizine.
Topics: Adult; Cetirizine; Drug Eruptions; Histamine H1 Antagonists, Non-Sedating; Humans; Lip; Male; Penis; | 2005 |
Oral allergy syndrome and contact urticaria to apples.
Topics: Apraxias; Cetirizine; Child; Food Hypersensitivity; Histamine H1 Antagonists, Non-Sedating; Humans; | 2005 |
Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines.
Topics: Animals; Cetirizine; CHO Cells; Cricetinae; Cricetulus; Histamine H1 Antagonists; Humans; Loratadine | 2005 |
Familial aquagenic urticaria and bernard-soulier syndrome.
Topics: Adult; Bernard-Soulier Syndrome; Cetirizine; Family Health; Female; Histamine H1 Antagonists, Non-Se | 2006 |
[Patient report: allergic rhinitis].
Topics: Absenteeism; Cetirizine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Histamine H1 An | 2005 |
Chronic unremitting urticaria: is the use of antihistamines above the licensed dose effective? A preliminary study of cetirizine at licensed and above-licensed doses.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Drug Administration Schedule; Female; Histamine H1 Antagon | 2007 |
Cellular adhesion molecules in chronic urticaria: modulation of serum levels occurs during levocetirizine treatment.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; E-Selectin; Enzyme-Linked Immunosorbent Assay; | 2006 |
Cost effectiveness of levocetirizine in chronic idiopathic urticaria : a pooled analysis of two randomised controlled trials.
Topics: Adult; Anti-Allergic Agents; Cetirizine; Chronic Disease; Cost-Benefit Analysis; Female; Health Care | 2006 |
Histamine, but not leukotriene C4, is an essential mediator in cold urticaria wheals.
Topics: Acetates; Adult; Anti-Allergic Agents; Cetirizine; Cold Temperature; Cyclopropanes; Female; Histamin | 2007 |
A case of urticaria induced by both hydroxyzine and cetirizine but not by levocetirizine.
Topics: Adult; Cetirizine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Piperazines; Urticaria | 2007 |
New hay fever, hives treatment approved.
Topics: Cetirizine; Chronic Disease; Clinical Trials as Topic; Histamine H1 Antagonists, Non-Sedating; Human | 2007 |
Depressive symptoms in urticaria patients treated with first- or second-generation histamine 1 receptor antagonists.
Topics: Adult; Aged; Cetirizine; Depressive Disorder; Female; Histamine H1 Antagonists; Histamine H1 Antagon | 2007 |
Levocetirizine (Xyzal) for allergic rhinitis and urticaria.
Topics: Cetirizine; Histamine H1 Antagonists; Humans; Piperazines; Rhinitis, Allergic, Perennial; Rhinitis, | 2007 |
Non-interventional study comparing treatment satisfaction in patients treated with antihistamines.
Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Aged, 80 and over; Cetirizine; Child; | 2008 |
Familial cold urticaria: a father and daughter with typical clinical and laboratory features.
Topics: Adult; Cetirizine; Cold Temperature; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Urt | 1995 |
Cetirizine may block transmigration of eosinophils at post-capillary venules.
Topics: Adult; Cell Movement; Cetirizine; Eosinophils; Female; Humans; Pressure; Urticaria; Venules | 1994 |
[Delayed pressure urticaria: therapeutic response to cetirizine].
Topics: Adult; Cetirizine; Humans; Hypersensitivity, Delayed; Male; Pressure; Urticaria | 1993 |
Cetirizine--a new antihistamine.
Topics: Adolescent; Adult; Anti-Allergic Agents; Bronchial Spasm; Bronchodilator Agents; Cetirizine; Double- | 1996 |
[Delayed-type pressure urticaria].
Topics: Adult; Angioedema; Anti-Allergic Agents; Cetirizine; Chronic Disease; Humans; Male; Urticaria | 1995 |
[Allergic reactions of skin and mucous membranes. New findings about etiology, pathology and therapy].
Topics: Cetirizine; Dermatitis; Dermatitis, Atopic; Eosinophils; Granulocytes; Histamine Antagonists; Humans | 1994 |
The clinical efficacy of H1 antagonists in urticaria and rhinitis.
Topics: Anti-Allergic Agents; Cetirizine; Histamine H1 Antagonists; Humans; Loratadine; Mathematical Computi | 1998 |
Cetirizine-induced urticarial reaction.
Topics: Adult; Cetirizine; Drug Eruptions; Female; Histamine H1 Antagonists; Humans; Urticaria | 1999 |
Fexofenadine: new preparation. Terfenadine, without cardiotoxicity.
Topics: Cetirizine; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Histamine Antagonists; Human | 1999 |
Urticaria induced by cetirizine.
Topics: Adult; Cetirizine; Drug Eruptions; Female; Histamine H1 Antagonists; Humans; Urticaria | 2001 |
Acute urticaria with elevated circulating interleukin-6 is resistant to anti-histamine treatment.
Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Cetirizine; Enzyme-Linked Immunosorbent | 2001 |
Acute urticaria with elevated circulating interleukin-6 is resistant to anti-histamine treatment.
Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Cetirizine; Enzyme-Linked Immunosorbent | 2001 |
Acute urticaria with elevated circulating interleukin-6 is resistant to anti-histamine treatment.
Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Cetirizine; Enzyme-Linked Immunosorbent | 2001 |
Acute urticaria with elevated circulating interleukin-6 is resistant to anti-histamine treatment.
Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Cetirizine; Enzyme-Linked Immunosorbent | 2001 |
Urticarial intolerance reaction to cetirizine.
Topics: Acute Disease; Adult; Anti-Allergic Agents; Cetirizine; Chronic Disease; Drug Eruptions; Female; His | 2002 |
[Effect of cetirizine, selective H1 antagonist of histamine on skin and bronchial reactivity and cellular histamine release in allergic diseases].
Topics: Asthma; Bronchial Provocation Tests; Cetirizine; Chronic Disease; Histamine; Humans; Neutrophils; Rh | 1992 |
Treatment of urticaria and angioedema: low-sedating H1-type antihistamines.
Topics: Angioedema; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine | 1991 |
Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria.
Topics: Adult; Blood Transfusion, Autologous; Cetirizine; Chronic Disease; Female; Histamine; Histamine H1 A | 1990 |
[Cetirizine in allergic symptoms. General practice relevance and a profile of effects. Resume of current studies].
Topics: Asthma; Cetirizine; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzine; Rhinitis, Allergic, | 1990 |
Late-phase cutaneous reactions to platelet activating factor and kallikrein in urticaria.
Topics: Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersens | 1990 |