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cetirizine and Renal Insufficiency

cetirizine has been researched along with Renal Insufficiency in 5 studies

Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.

Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research Excerpts

ExcerptRelevanceReference
"A 72-year-old woman with renal insufficiency who was taking oral pilsicainide (150 mg/d) complained of feeling faint 3 days after she was prescribed oral cetirizine (20 mg/d)."9.12Severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency: first case presentation showing competition for excretion via renal multidrug resistance protein 1 and organic cation transporter 2. ( Fujimura, A; Ioka, T; Ookami, H; Sakamoto, K; Tsuruoka, S; Wakaumi, M, 2006)
"Elevated plasma histamine levels are considered to play a part in the pathophysiology of hemodialysis-related pruritus."9.10Plasma serotonin and histamine levels in hemodialysis-related pruritus are not significantly influenced by 5-HT3 receptor blocker and antihistaminic therapy. ( Domröse, U; Dunker, N; Gollnick, H; Neumann, KH; Weisshaar, E, 2003)
"A 72-year-old woman with renal insufficiency who was taking oral pilsicainide (150 mg/d) complained of feeling faint 3 days after she was prescribed oral cetirizine (20 mg/d)."5.12Severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency: first case presentation showing competition for excretion via renal multidrug resistance protein 1 and organic cation transporter 2. ( Fujimura, A; Ioka, T; Ookami, H; Sakamoto, K; Tsuruoka, S; Wakaumi, M, 2006)
"Elevated plasma histamine levels are considered to play a part in the pathophysiology of hemodialysis-related pruritus."5.10Plasma serotonin and histamine levels in hemodialysis-related pruritus are not significantly influenced by 5-HT3 receptor blocker and antihistaminic therapy. ( Domröse, U; Dunker, N; Gollnick, H; Neumann, KH; Weisshaar, E, 2003)
"Pruritus is the most distressing symptom in haemodialysis (HD) patients."2.71Antipruritic effects of two different 5-HT3 receptor antagonists and an antihistamine in haemodialysis patients. ( Dunker, N; Gollnick, H; Röhl, FW; Weisshaar, E, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weisshaar, E2
Dunker, N2
Domröse, U1
Neumann, KH1
Gollnick, H2
Wang, F1
Dupuis, JY1
Nathan, H1
Williams, K1
Röhl, FW1
Tsuruoka, S1
Ioka, T1
Wakaumi, M1
Sakamoto, K1
Ookami, H1
Fujimura, A1
Whomsley, R1
Strolin-Benedetti, M1
Baltes, E1

Trials

3 trials available for cetirizine and Renal Insufficiency

ArticleYear
Plasma serotonin and histamine levels in hemodialysis-related pruritus are not significantly influenced by 5-HT3 receptor blocker and antihistaminic therapy.
    Clinical nephrology, 2003, Volume: 59, Issue:2

    Topics: Adult; Cetirizine; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Indoles; Male;

2003
Antipruritic effects of two different 5-HT3 receptor antagonists and an antihistamine in haemodialysis patients.
    Experimental dermatology, 2004, Volume: 13, Issue:5

    Topics: Adult; Aged; Antipruritics; Cetirizine; Female; Histamine; Histamine H1 Antagonists; Humans; Indoles

2004
Severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency: first case presentation showing competition for excretion via renal multidrug resistance protein 1 and organic cation transporter 2.
    Clinical pharmacology and therapeutics, 2006, Volume: 79, Issue:4

    Topics: Administration, Oral; Adult; Aged; Animals; Anti-Arrhythmia Agents; Area Under Curve; Arrhythmias, C

2006

Other Studies

2 other studies available for cetirizine and Renal Insufficiency

ArticleYear
An analysis of the association between preoperative renal dysfunction and outcome in cardiac surgery: estimated creatinine clearance or plasma creatinine level as measures of renal function.
    Chest, 2003, Volume: 124, Issue:5

    Topics: Aged; Analysis of Variance; Cardiac Surgical Procedures; Cetirizine; Creatinine; Female; Glomerular

2003
Comment on severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:6

    Topics: Aged; Area Under Curve; Arrhythmias, Cardiac; Cetirizine; Drug Interactions; Female; Half-Life; Huma

2006