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cetirizine and Innate Inflammatory Response

cetirizine has been researched along with Innate Inflammatory Response in 12 studies

Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.

Research Excerpts

ExcerptRelevanceReference
"The CIRANO study suggests that levocetirizine is effective on PER symptoms, including a transient improvement in loss of smell, and that this improvement concurs more with reduction of nasal inflammation than of nasal patency."9.16The loss of smell in persistent allergic rhinitis is improved by levocetirizine due to reduction of nasal inflammation but not nasal congestion (the CIRANO study). ( Alobid, I; Bernal-Sprekelsen, M; Centellas, S; García-Piñero, A; Guilemany, JM; Mariño, FS; Mullol, J; Picado, C; Valero, A, 2012)
"Nasal obstruction is the main symptom in patients with perennial allergic rhinitis."6.71Desloratadine and levocetirizine improve nasal symptoms, airflow, and allergic inflammation in patients with perennial allergic rhinitis: a pilot study. ( Allen, M; Barberi, S; Ciprandi, G; Cirillo, I; Civardi, E; Marseglia, GL; Vizzaccaro, A, 2005)
"The CIRANO study suggests that levocetirizine is effective on PER symptoms, including a transient improvement in loss of smell, and that this improvement concurs more with reduction of nasal inflammation than of nasal patency."5.16The loss of smell in persistent allergic rhinitis is improved by levocetirizine due to reduction of nasal inflammation but not nasal congestion (the CIRANO study). ( Alobid, I; Bernal-Sprekelsen, M; Centellas, S; García-Piñero, A; Guilemany, JM; Mariño, FS; Mullol, J; Picado, C; Valero, A, 2012)
"The present open label study in 62 patients indicates that levocetirizine 5 mg reliably controls persistent rhinitis over a period of 6 months, and shows a trend to be more effective in controlling the symptoms of rhinitis, improving QOL and decreasing nasal inflammation, when administered as long-term continuous therapy rather than as on-demand therapy."5.13Levocetirizine in persistent allergic rhinitis: continuous or on-demand use? A pilot study. ( Baiardini, I; Canonica, GW; Compalati, E; Fumagalli, F; Gamalero, C; Guerra, L; Massacane, P; Passalacqua, G; Riccio, AM; Rogkakou, A; Scordamaglia, A, 2008)
"The presented results indicate the effectiveness of theoritin and cetirizine in the treatment of patients with seasonal exacerbation of allergic rhinitis, comorbid for acute respiratory viral infections."4.12[Modern H1 antihistamines in the treatment of patients with allergic rhinitis and comorbid acute respiratory infections]. ( Miroshnichenko, NA; Nikolaeva, YO; Ovchinnikov, AY, 2022)
"Acute skin inflammation occurs following topical aminolevulinic acid-photodynamic therapy (ALA-PDT), but its nature and mediation are ill defined."3.73Histamine is released following aminolevulinic acid-photodynamic therapy of human skin and mediates an aminolevulinic acid dose-related immediate inflammatory response. ( Brooke, RC; Church, MK; Clough, GF; Friedmann, PS; Rhodes, LE; Sidhu, MK; Sinha, A; Watson, RE, 2006)
"Nasal obstruction is the main symptom in patients with perennial allergic rhinitis."2.71Desloratadine and levocetirizine improve nasal symptoms, airflow, and allergic inflammation in patients with perennial allergic rhinitis: a pilot study. ( Allen, M; Barberi, S; Ciprandi, G; Cirillo, I; Civardi, E; Marseglia, GL; Vizzaccaro, A, 2005)
"Cetirizine treatment had no significant effect on these responses."2.68Cellular inflammatory responses during immediate, developing, and established late-phase allergic cutaneous reactions: effects of cetirizine. ( Atkins, PC; Ciliberti, M; Grossman, S; Moskovitz, A; von Allmen, C; Zweiman, B, 1997)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's4 (33.33)29.6817
2010's1 (8.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Ovchinnikov, AY1
Miroshnichenko, NA1
Nikolaeva, YO1
Bielory, L1
Canonica, GW1
Fumagalli, F1
Guerra, L1
Baiardini, I1
Compalati, E1
Rogkakou, A1
Massacane, P1
Gamalero, C1
Riccio, AM1
Scordamaglia, A1
Passalacqua, G1
Guilemany, JM1
García-Piñero, A1
Alobid, I1
Centellas, S1
Mariño, FS1
Valero, A1
Bernal-Sprekelsen, M1
Picado, C1
Mullol, J1
Giustizieri, ML1
Albanesi, C1
Fluhr, J1
Gisondi, P1
Norgauer, J1
Girolomoni, G1
Ciprandi, G1
Cirillo, I1
Vizzaccaro, A1
Civardi, E1
Barberi, S1
Allen, M1
Marseglia, GL1
Brooke, RC1
Sinha, A1
Sidhu, MK1
Watson, RE1
Church, MK1
Friedmann, PS1
Clough, GF1
Rhodes, LE1
Zweiman, B1
Atkins, PC1
Moskovitz, A1
von Allmen, C1
Ciliberti, M1
Grossman, S1
Hayashi, S1
Hashimoto, S1
Ollier, S1
Varney, V1
Gaga, M1
Frew, AJ1
De Vos, C1
Kay, AB1
Snyman, JR1
Sommers, DK1
Gregorowski, MD1
Boraine, H1

Trials

6 trials available for cetirizine and Innate Inflammatory Response

ArticleYear
Levocetirizine in persistent allergic rhinitis: continuous or on-demand use? A pilot study.
    Current medical research and opinion, 2008, Volume: 24, Issue:10

    Topics: Adult; Aged; Cetirizine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Inflammation; Male;

2008
The loss of smell in persistent allergic rhinitis is improved by levocetirizine due to reduction of nasal inflammation but not nasal congestion (the CIRANO study).
    International archives of allergy and immunology, 2012, Volume: 158, Issue:2

    Topics: Adult; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Infl

2012
Desloratadine and levocetirizine improve nasal symptoms, airflow, and allergic inflammation in patients with perennial allergic rhinitis: a pilot study.
    International immunopharmacology, 2005, Volume: 5, Issue:13-14

    Topics: Adolescent; Adult; Cetirizine; Double-Blind Method; Eosinophils; Female; Histamine H1 Antagonists, N

2005
Cellular inflammatory responses during immediate, developing, and established late-phase allergic cutaneous reactions: effects of cetirizine.
    The Journal of allergy and clinical immunology, 1997, Volume: 100, Issue:3

    Topics: Administration, Cutaneous; Anti-Allergic Agents; Biopsy; Blood Proteins; Cetirizine; Codeine; Eosino

1997
The effect of a single oral dose of prednisolone or cetirizine on inflammatory cells infiltrating allergen-induced cutaneous late-phase reactions in atopic subjects.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1992, Volume: 22, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Allergens; Cetirizine; Double-Blind Method; Histamine H1 An

1992
Effect of cetirizine, ketotifen and chlorpheniramine on the dynamics of the cutaneous hypersensitivity reaction: a comparative study.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:4

    Topics: Basophils; Cetirizine; Chlorpheniramine; Dermatitis, Contact; Double-Blind Method; Eosinophils; Hist

1992

Other Studies

6 other studies available for cetirizine and Innate Inflammatory Response

ArticleYear
[Modern H1 antihistamines in the treatment of patients with allergic rhinitis and comorbid acute respiratory infections].
    Vestnik otorinolaringologii, 2022, Volume: 87, Issue:3

    Topics: Adult; Cetirizine; Female; Histamine Antagonists; Histamine H1 Antagonists; Humans; Inflammation; Ma

2022
Allergic inflammation of the anterior surface of the eye.
    Allergy and asthma proceedings, 2020, 11-01, Volume: 41, Issue:6

    Topics: Adult; Cetirizine; Child; Conjunctivitis, Allergic; Eye; Histamine H1 Antagonists; Humans; Hypersens

2020
H1 histamine receptor mediates inflammatory responses in human keratinocytes.
    The Journal of allergy and clinical immunology, 2004, Volume: 114, Issue:5

    Topics: Adult; Cells, Cultured; Cetirizine; Chemokines; Female; Granulocyte-Macrophage Colony-Stimulating Fa

2004
Histamine is released following aminolevulinic acid-photodynamic therapy of human skin and mediates an aminolevulinic acid dose-related immediate inflammatory response.
    The Journal of investigative dermatology, 2006, Volume: 126, Issue:10

    Topics: Adult; Aged; Aminolevulinic Acid; Cetirizine; Dose-Response Relationship, Drug; Erythema; Female; Hi

2006
Anti-inflammatory actions of new antihistamines.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29, Issue:12

    Topics: Anti-Inflammatory Agents; Cetirizine; Cytokines; Epithelial Cells; Histamine H1 Antagonists; Humans;

1999
Cutaneous responses--a window on inflammatory processes.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1992, Volume: 22, Issue:1

    Topics: Cetirizine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Inflammation; Skin

1992