cetirizine has been researched along with Electrocardiogram QT Prolonged in 8 studies
Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifteen asymptomatic patients with type 1 (LQT1), 15 patients with type 2 (LQT2) long QT syndrome, and 15 healthy volunteers took a placebo and cetirizine 10 mg." | 9.12 | The effect of antihistamine cetirizine on ventricular repolarization in congenital long QT syndrome. ( Hekkala, AM; Swan, H; Toivonen, L; Väänänen, H; Viitasalo, M, 2007) |
| " We compared cetirizine, another compound of that class, to D-sotalol and to astemizole in a model of acquired long QT syndrome." | 7.70 | Electrophysiological effects of cetirizine, astemizole and D-sotalol in a canine model of long QT syndrome. ( Cheymol, G; Jaillon, P; Noyer, M; Weissenburger, J, 1999) |
| "Fifteen asymptomatic patients with type 1 (LQT1), 15 patients with type 2 (LQT2) long QT syndrome, and 15 healthy volunteers took a placebo and cetirizine 10 mg." | 5.12 | The effect of antihistamine cetirizine on ventricular repolarization in congenital long QT syndrome. ( Hekkala, AM; Swan, H; Toivonen, L; Väänänen, H; Viitasalo, M, 2007) |
| " We compared cetirizine, another compound of that class, to D-sotalol and to astemizole in a model of acquired long QT syndrome." | 3.70 | Electrophysiological effects of cetirizine, astemizole and D-sotalol in a canine model of long QT syndrome. ( Cheymol, G; Jaillon, P; Noyer, M; Weissenburger, J, 1999) |
| "Cetirizine is a metabolite of hydroxyzine, another antihistamine." | 2.46 | Cetirizine and loratadine: minimal risk of QT prolongation. ( , 2010) |
| "The long QT syndrome is a rare disease." | 1.33 | Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs. ( Codreanu, A; de Chillou, C; Moneret-Vautrin, DA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Darpo, B | 1 |
| Benson, C | 1 |
| Brown, R | 1 |
| Dota, C | 1 |
| Ferber, G | 1 |
| Ferry, J | 1 |
| Jarugula, V | 1 |
| Keirns, J | 1 |
| Ortemann-Renon, C | 1 |
| Pham, T | 1 |
| Riley, S | 1 |
| Sarapa, N | 1 |
| Ticktin, M | 1 |
| Zareba, W | 1 |
| Couderc, JP | 1 |
| Gravel, AE | 1 |
| Arnold, AA | 1 |
| Dufourc, EJ | 1 |
| Marcotte, I | 1 |
| Lehman, JM | 1 |
| Blaiss, MS | 1 |
| Moneret-Vautrin, DA | 1 |
| de Chillou, C | 1 |
| Codreanu, A | 1 |
| Hekkala, AM | 1 |
| Swan, H | 1 |
| Väänänen, H | 1 |
| Viitasalo, M | 1 |
| Toivonen, L | 1 |
| Hulhoven, R | 1 |
| Rosillon, D | 1 |
| Letiexhe, M | 1 |
| Meeus, MA | 1 |
| Daoust, A | 1 |
| Stockis, A | 1 |
| Weissenburger, J | 1 |
| Noyer, M | 1 |
| Cheymol, G | 1 |
| Jaillon, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical ECG Study to Evaluate Electrophysiological Effects of Potential QT Prolonging Drugs With Novel ECG Biomarkers With Exposure-Response Analysis[NCT05716854] | Phase 1 | 44 participants (Actual) | Interventional | 2023-03-21 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for cetirizine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Cetirizine and loratadine: minimal risk of QT prolongation.
Topics: Anti-Allergic Agents; Cetirizine; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; | 2010 |
Selecting the optimal oral antihistamine for patients with allergic rhinitis.
Topics: Administration, Oral; Cardiovascular System; Central Nervous System; Cetirizine; Drug Interactions; | 2006 |
3 trials available for cetirizine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Evaluation of the Effect of 5 QT-Positive Drugs on the JTpeak Interval - An Analysis of ECGs From the IQ-CSRC Study.
Topics: Arrhythmias, Cardiac; Biomarkers; Cetirizine; Drug-Related Side Effects and Adverse Reactions; Elect | 2020 |
The effect of antihistamine cetirizine on ventricular repolarization in congenital long QT syndrome.
Topics: Adult; Cetirizine; Female; Heart Defects, Congenital; Heart Rate; Heart Ventricles; Histamine H1 Ant | 2007 |
Levocetirizine does not prolong the QT/QTc interval in healthy subjects: results from a thorough QT study.
Topics: Adolescent; Adult; Aza Compounds; Cetirizine; Cross-Over Studies; Dose-Response Relationship, Drug; | 2007 |
3 other studies available for cetirizine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
An NMR investigation of the structure, function and role of the hERG channel selectivity filter in the long QT syndrome.
Topics: Bepridil; Cetirizine; Dimyristoylphosphatidylcholine; Diphenhydramine; ERG1 Potassium Channel; Ether | 2013 |
Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs.
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Asthmatic Agents; Butyrophenones; Cetirizine; Conjunct | 2006 |
Electrophysiological effects of cetirizine, astemizole and D-sotalol in a canine model of long QT syndrome.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Astemizole; Cetirizine; Dogs; Dose-Response Rela | 1999 |