cetirizine has been researched along with Disease Models, Animal in 19 studies
Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intrathecally injected histamine increased incapacitation and articular edema, whereas the H1R antagonist, cetirizine, decreased both parameters." | 7.83 | Histaminergic Pharmacology Modulates the Analgesic and Antiedematogenic Effects of Spinally Injected Morphine. ( Eto, C; Fin, FE; Mascarin, L; Souza-Silva, E; Stein, T; Tonussi, CR, 2016) |
| "Postcolitis rats displayed a higher number of colonic mast cells, excessive histamine release and significantly enhanced VMRs." | 7.80 | Histamine H4 and H1 receptors contribute to postinflammatory visceral hypersensitivity. ( De Man, JG; De Winter, BY; Deiteren, A; Moreels, TG; Pelckmans, PA; Ruyssers, NE, 2014) |
| "The present study investigated the involvement of mediodorsal thalamic (MD) GABA-A receptors in cetirizine/morphine-induced anti-allodynia using a rat model of neuropathic pain." | 4.31 | Pharmacological activation of mediodorsal thalamic GABA-A receptors modulates morphine/cetirizine-induced changes in the prefrontal cortical GFAP expression in a rat model of neuropathic pain. ( Alijanpour, S; Asgharpour-Masouleh, N; Delphi, L; Rezayof, A, 2023) |
| "Intrathecally injected histamine increased incapacitation and articular edema, whereas the H1R antagonist, cetirizine, decreased both parameters." | 3.83 | Histaminergic Pharmacology Modulates the Analgesic and Antiedematogenic Effects of Spinally Injected Morphine. ( Eto, C; Fin, FE; Mascarin, L; Souza-Silva, E; Stein, T; Tonussi, CR, 2016) |
| "Postcolitis rats displayed a higher number of colonic mast cells, excessive histamine release and significantly enhanced VMRs." | 3.80 | Histamine H4 and H1 receptors contribute to postinflammatory visceral hypersensitivity. ( De Man, JG; De Winter, BY; Deiteren, A; Moreels, TG; Pelckmans, PA; Ruyssers, NE, 2014) |
| "Cetirizine (Zytec) is often used as a histamine receptor-1 (H(1)) antagonist in rhinitis patients who are suffering from sneezing and rhinorrhea." | 3.75 | Effects of cetirizine on isolated rat's tracheal smooth muscle. ( Chu, YH; Kao, CH; Wang, HW, 2009) |
| "The following study was performed to further characterize a primate model of asthma using classes of drugs that target allergy (pyrilamine, cetirizine), are bronchodilators for the treatment of asthma (salbutamol, salmeterol) or are anti-inflammatory (dexamethasone)." | 3.69 | Characterization of a primate model of asthma using anti-allergy/anti-asthma agents. ( Andresen, CJ; Smith, WB; Turner, CR; Watson, JW, 1996) |
| "The cause of chronic pelvic pain in interstitial cystitis/painful bladder syndrome (IC/PBS) remains unclear; autoimmunity is a possible etiology." | 1.42 | Chronic pelvic allodynia is mediated by CCL2 through mast cells in an experimental autoimmune cystitis model. ( Altuntas, CZ; Bicer, F; Daneshgari, F; Izgi, K; Kavran, M; Ozer, A; Tuohy, VK, 2015) |
| "Montelukast has not been reported to have major effects on sneezing and itching in the clinic but reduces nasal obstruction (lower nasal airway pressure or nasal patency)." | 1.35 | Differential responses to various classes of drugs in a model of allergic rhinitis in guinea pigs. ( Al Suleimani, YM; Dong, Y; Walker, MJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Avdeef, A | 1 |
| Tam, KY | 1 |
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Chen, H | 1 |
| Cheng, Y | 1 |
| Du, H | 1 |
| Zhang, C | 1 |
| Zhou, Y | 1 |
| Zhao, Z | 1 |
| Li, Y | 1 |
| Friedemann, T | 1 |
| Mei, J | 1 |
| Schröder, S | 1 |
| Chen, M | 1 |
| Asgharpour-Masouleh, N | 1 |
| Rezayof, A | 1 |
| Alijanpour, S | 1 |
| Delphi, L | 1 |
| Deiteren, A | 1 |
| De Man, JG | 1 |
| Ruyssers, NE | 1 |
| Moreels, TG | 1 |
| Pelckmans, PA | 1 |
| De Winter, BY | 1 |
| Raveendran, VV | 1 |
| Kassel, KM | 1 |
| Smith, DD | 1 |
| Luyendyk, JP | 1 |
| Williams, KJ | 1 |
| Cherian, R | 1 |
| Reed, GA | 1 |
| Flynn, CA | 1 |
| Csanaky, IL | 1 |
| Lickteig, AL | 1 |
| Pratt-Hyatt, MJ | 1 |
| Klaassen, CD | 1 |
| Dileepan, KN | 1 |
| Liu, SC | 1 |
| Chu, YH | 2 |
| Kao, CH | 2 |
| Wu, CC | 1 |
| Wang, HW | 2 |
| Bicer, F | 1 |
| Altuntas, CZ | 1 |
| Izgi, K | 1 |
| Ozer, A | 1 |
| Kavran, M | 1 |
| Tuohy, VK | 1 |
| Daneshgari, F | 1 |
| Stein, T | 1 |
| Souza-Silva, E | 1 |
| Mascarin, L | 1 |
| Eto, C | 1 |
| Fin, FE | 1 |
| Tonussi, CR | 1 |
| Yokota, E | 2 |
| Kuyama, S | 2 |
| Ogawa, M | 2 |
| Kamei, C | 3 |
| Sugimoto, Y | 1 |
| Bäumer, W | 1 |
| Stahl, J | 1 |
| Sander, K | 1 |
| Petersen, LJ | 1 |
| Paps, J | 1 |
| Stark, H | 1 |
| Kietzmann, M | 1 |
| Olivry, T | 1 |
| Minami, K | 1 |
| Fujii, Y | 1 |
| Al Suleimani, YM | 1 |
| Dong, Y | 1 |
| Walker, MJ | 1 |
| Chimona, TS | 1 |
| Panayiotides, JG | 1 |
| Papadakis, CE | 1 |
| Helidonis, ES | 1 |
| Velegrakis, GA | 1 |
| Turner, CR | 1 |
| Andresen, CJ | 1 |
| Smith, WB | 1 |
| Watson, JW | 1 |
| Musoh, K | 1 |
| Maeda, Y | 1 |
| Tanaka, H | 1 |
| Inagaki, N | 1 |
| Nagai, H | 1 |
19 other studies available for cetirizine and Disease Models, Animal
| Article | Year |
|---|---|
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological | 2010 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Shufeng Jiedu capsule ameliorates olfactory dysfunction via the AMPK/mTOR autophagy pathway in a mouse model of allergic rhinitis.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Allergic Agents; Anti-Bacterial Agents; Anti-Inflammato | 2022 |
Pharmacological activation of mediodorsal thalamic GABA-A receptors modulates morphine/cetirizine-induced changes in the prefrontal cortical GFAP expression in a rat model of neuropathic pain.
Topics: Animals; Cetirizine; Chronic Pain; Disease Models, Animal; GABA-A Receptor Agonists; Glial Fibrillar | 2023 |
Histamine H4 and H1 receptors contribute to postinflammatory visceral hypersensitivity.
Topics: Animals; Cetirizine; Colitis; Colonoscopy; Convalescence; Disease Models, Animal; Histamine; Histami | 2014 |
H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice.
Topics: Animals; Apolipoproteins E; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Ca | 2014 |
Steroids and antihistamines synergize to inhibit rat's airway smooth muscle contractility.
Topics: Animals; Cetirizine; Cholinergic Agents; Disease Models, Animal; Drug Synergism; Electric Stimulatio | 2015 |
Chronic pelvic allodynia is mediated by CCL2 through mast cells in an experimental autoimmune cystitis model.
Topics: Animals; Cetirizine; Chemokine CCL2; Cromolyn Sodium; Cystitis, Interstitial; Disease Models, Animal | 2015 |
Histaminergic Pharmacology Modulates the Analgesic and Antiedematogenic Effects of Spinally Injected Morphine.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Carrageenan; Cetirizine; Disease Models, Anim | 2016 |
Substance P is involved in the effect of histamine H3 receptor agonist, Sch 50971 on nasal allergic symptoms in mice.
Topics: Animals; Capsaicin; Cetirizine; Disease Models, Animal; Female; Histamine; Histamine Agonists; Hista | 2008 |
Participation of histamine H3 receptors in experimental allergic rhinitis of mice.
Topics: Animals; Anti-Allergic Agents; Cetirizine; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Respo | 2008 |
Effects of cetirizine on isolated rat's tracheal smooth muscle.
Topics: Animals; Anti-Allergic Agents; Cerebrospinal Fluid Rhinorrhea; Cetirizine; Disease Models, Animal; M | 2009 |
Lack of preventing effect of systemically and topically administered histamine H(1) or H(4) receptor antagonists in a dog model of acute atopic dermatitis.
Topics: Aging; Animals; Antigens, Dermatophagoides; Cetirizine; Dermatitis, Atopic; Dermatophagoides farinae | 2011 |
Participation of chemical mediators in the development of experimental allergic conjunctivitis in rats.
Topics: Administration, Oral; Animals; Carbazoles; Cetirizine; Conjunctivitis, Allergic; Disease Models, Ani | 2004 |
Differential responses to various classes of drugs in a model of allergic rhinitis in guinea pigs.
Topics: Acetates; Acute Disease; Animals; Cetirizine; Cyclopropanes; Dexamethasone; Disease Models, Animal; | 2008 |
Antihistamine effects on experimental middle ear inflammatory model.
Topics: Animals; Cetirizine; Disease Models, Animal; Ear, Middle; Female; Histamine H1 Antagonists, Non-Seda | 2008 |
Characterization of a primate model of asthma using anti-allergy/anti-asthma agents.
Topics: Albuterol; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Antigens; Asthma; Bronchoconstri | 1996 |
Effect of a novel anti-allergic agent, HSR-609, on antigen-induced airway hyperresponsiveness in mice.
Topics: Acetylcholine; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Benzoxepins; Bronchial Hyper | 2000 |