cetirizine has been researched along with Disease Exacerbation in 5 studies
Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In order to elucidate how pharmacological inhibition of histamine receptor 1 (H1R) signaling affects atherogenesis, we administered either cetirizine (1 and 4 mg/kg." | 3.80 | Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice. ( Dileepan, KN; Flynn, CA; Milne, G; Raveendran, VV; Reed, GA; Smith, DD; Sweeney, ME; Tan, X; Tawfik, OW, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rorie, A | 1 |
| Goldner, WS | 1 |
| Lyden, E | 1 |
| Poole, JA | 1 |
| Raveendran, VV | 1 |
| Smith, DD | 1 |
| Tan, X | 1 |
| Sweeney, ME | 1 |
| Reed, GA | 1 |
| Flynn, CA | 1 |
| Tawfik, OW | 1 |
| Milne, G | 1 |
| Dileepan, KN | 1 |
| Asero, R | 1 |
| Tedeschi, A | 1 |
| Cugno, M | 1 |
| Cobo Calvo, A | 1 |
| Albertí Aguiló, MA | 1 |
| Casasnovas Pons, C | 1 |
| Miyagawa, F | 1 |
| Danno, K | 1 |
| Uehara, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of Vitamin D in Chronic Urticaria and Angioedema Treatment[NCT01371877] | 42 participants (Actual) | Interventional | 2011-11-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Unit of Measure is Safety and Tolerability. The number of participants with adverse events will be compared between the groups using the independent sample t-test (assuming the distribution is normal). (NCT01371877)
Timeframe: 3 month study trial
| Intervention | participants (Number) |
|---|---|
| High Dose Vitamin D | 0 |
| Low Dose Vitamin D | 0 |
The Unit of Measure is Efficacy. The primary outcome of this study is to determine if vitamin D supplementation reduces the medication usage in subjects with CUA. Thus, for the outcome of reduction in pills, at 12 weeks, subjects whose pill usage decreases by 2 or more pills per day will be classified as improved. Subjects whose pill consumption did not change or increased will be classified as unchanged. (NCT01371877)
Timeframe: 12 week intervention
| Intervention | number of pills/day (Mean) | |
|---|---|---|
| Baseline medication usage | 3 month medication usage | |
| High Dose Vitamin D | 2.8 | 2.0 |
| Low Dose Vitamin D | 4.6 | 4.9 |
The Unit of Measure is Efficacy. The Total Urticaria Severity Score (USS) ranges from 0 to 93, higher scores = worse symptoms. This secondary outcome of this study is to determine if high dose vitamin D supplementation improves the urticaria severity score (USS). The change in USS will be compared between the groups using the independent sample t-test (assuming the distribution is normal). Logistic regression and multiple linear regression will be used to adjust for possible confounders. (NCT01371877)
Timeframe: 3 month intervention
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Baseline Total Urticaria Score | 1 week Total Urticaria Score | 3 month Total Urticaria Score | |
| High Dose Vitamin D | 41.14 | 25.48 | 15.0 |
| Low Dose Vitamin D | 40.1 | 29.24 | 24.1 |
1 trial available for cetirizine and Disease Exacerbation
| Article | Year |
|---|---|
Beneficial role for supplemental vitamin D3 treatment in chronic urticaria: a randomized study.
Topics: Acetates; Adult; Aged; Cetirizine; Cholecalciferol; Chronic Disease; Cyclopropanes; Dietary Suppleme | 2014 |
4 other studies available for cetirizine and Disease Exacerbation
| Article | Year |
|---|---|
Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice.
Topics: Analysis of Variance; Animals; Apolipoproteins E; Atherosclerosis; Blood Chemical Analysis; CD36 Ant | 2014 |
Heparin and tranexamic Acid therapy may be effective in treatment-resistant chronic urticaria with elevated d-dimer: a pilot study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Cetirizine; Chr | 2010 |
Myasthenia gravis exacerbation after cetirizine administration.
Topics: Cetirizine; Disease Progression; Female; Humans; Myasthenia Gravis; Young Adult | 2011 |
Erythema gyratum repens responding to cetirizine hydrochloride.
Topics: Administration, Oral; Biopsy, Needle; Cetirizine; Disease Progression; Erythema Multiforme; Fatal Ou | 2002 |