cetirizine and Chronic Disease
cetirizine has been researched along with Chronic Disease in 74 studies
Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Combination of cetirizine with ranitidine was not more effective than cetirizine alone in chronic urticaria." | 9.20 | Safety and efficacy of cetirizine versus cetirizine plus ranitidine in chronic urticaria: Double-blind randomized placebo-controlled study. ( Bonilla-Lopez, S; Guevara-Gutierrez, E; Hernández-Arana, S; Tlacuilo-Parra, A, 2015) |
"Cetirizine is commonly used in the treatment of urticaria." | 9.19 | Clinical effectiveness and safety of cetirizine versus rupatadine in chronic spontaneous urticaria: a randomized, double-blind, 6-week trial. ( Dakhale, GN; Hiware, SK; Mahatme, MS; Mishra, DB; Mukhi, JI; Salve, AM; Shinde, AT, 2014) |
"Levocetirizine led to a significantly greater decrease in pruritus severity than desloratadine over the first treatment week; mean pruritus severity scores of 1." | 9.14 | Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients. ( Finlay, AY; Guillet, G; Hauptmann, P; Jian, AM; Kapp, A; Maurer, M; Potter, PC, 2009) |
"Bilastine is a novel nonsedative H(1)-receptor antagonist, which may be used for the symptomatic treatment of chronic idiopathic urticaria (CU)." | 9.14 | Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study. ( Antépara, I; Bogacka, E; Jáuregui, I; Medina, I; Oanta, A; Uhl, P; Valiente, R; Wesel, F; Zuberbier, T, 2010) |
"Eighty tertiary referral patients with chronic urticaria (age range, 19-67 years) were randomized for double-blind treatment with levocetirizine or desloratadine (40/40)." | 9.14 | The effectiveness of levocetirizine and desloratadine in up to 4 times conventional doses in difficult-to-treat urticaria. ( Church, DS; Church, MK; Dimitrov, V; Kraeva, S; Kralimarkova, T; Lazarova, C; Popov, TA; Popova, D; Staevska, M, 2010) |
"A 4-week randomized, double-blind safety and efficacy study was conducted to compare the safety and efficacy of cetirizine, doxepine, and hydroxyzine 5 in the treatment of chronic pruritus due to sulfur mustard." | 9.12 | Cetirizine, doxepine, and hydroxyzine in the treatment of pruritus due to sulfur mustard: a randomized clinical trial. ( Davoudi, SM; Keshavarz, S; Sadr, B; Shohrati, M; Tajik, A, 2007) |
"To determine whether levocetirizine is efficacious in the treatment of chronic idiopathic urticaria." | 9.12 | Levocetirizine in the treatment of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study. ( Barra, L; Colanardi, MC; Ferrannini, A; Nettis, E; Tursi, A; Vacca, A, 2006) |
"A double-blinded, placebo-controlled trial comparing cetirizine 10 mg daily in combination with zafirlukast 20 mg twice a day versus cetirizine 10 mg daily and placebo was conducted to determine whether subjects with chronic urticaria benefit from add-on therapy with a leukotriene-modifying agent." | 9.11 | The addition of zafirlukast to cetirizine improves the treatment of chronic urticaria in patients with positive autologous serum skin test results. ( Bagenstose, SE; Bernstein, JA; Levin, L, 2004) |
"The results of the present study suggest that cetirizine may represent an effective and safe pharmacologic therapy for chronic urticaria in preschool children." | 9.09 | Double-blind multicenter study on the efficacy and tolerability of cetirizine compared with oxatomide in chronic idiopathic urticaria in preschool children. ( Barberio, G; Corrias, A; Grimaldi, I; La Rosa, M; Leonardi, S; Marchese, G; Oggiano, N, 2001) |
"The results of this comparative study demonstrate that montelukast orally administered once a day is very effective for the treatment of cutaneous symptoms in patients with chronic urticaria due to food additives and/or ASA." | 9.09 | Efficacy of leukotriene receptor antagonist in chronic urticaria. A double-blind, placebo-controlled comparison of treatment with montelukast and cetirizine in patients with chronic urticaria with intolerance to food additive and/or acetylsalicylic acid. ( Corrocher, R; Di Lorenzo, G; Pacor, ML, 2001) |
"In this study co-administration of hydroxyzine with cimetidine resulted in significantly increased serum hydroxyzine concentrations and increased wheal and flare suppression, thus confirming the rationale for a trial of concomitant administration of these medications in some patients with chronic urticaria unresponsive to treatment with an H1-antagonist alone." | 9.08 | Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria. ( Simons, FE; Simons, KJ; Sussman, GL, 1995) |
"Cetirizine 10 mg once daily was equivalent to hydroxyzine 25 mg tid in controlling the symptoms of patients with chronic urticaria, as assessed by patient and investigator evaluations." | 9.08 | Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria. ( Breneman, DL, 1996) |
"Our randomised study in parallel groups, double-blind double placebo, has compared the efficacy, onset of action and safety of terfenadine and cetirizine in chronic idiopathic urticaria." | 9.07 | [Double-blind comparative study of terfenadine and cetirizine in chronic idiopathic urticaria]. ( Bloom, M; Danglas, P; Hantzperg, M; Lambert, D, 1993) |
"The efficacy of cetirizine dihydrochloride, a new H1-antagonist claimed to have minimal sedative property was evaluated in 28 patients with chronic idiopathic urticaria." | 9.07 | Cetirizine vs placebo in chronic idiopathic urticaria--a double blind randomised cross-over study. ( Goh, CL; Lim, J; Wong, WK, 1991) |
"In a 20-d, double-blind, randomized, parallel study, the efficacy of cetirizine and terfenadine was compared in 30 patients with chronic idiopathic urticaria." | 9.07 | A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria. ( Andri, G; Andri, L; Betteli, C; Givanni, S; Lombardi, C; Mezzelani, P; Senna, GE, 1993) |
"Clinical trials of a new histamine H1-blocker of the III generation zyrtec (cetirizine) manufactured in Belgium (UCB) demonstrated its high efficacy in pollenosis and chronic idiopathic urticaria." | 9.07 | [The efficacy of the Zirtek (cetirizine) preparation in chronic recurrent urticaria and seasonal allergic rhinitis]. ( Androsov, VN; Belostotskaia, OI; Il'ina, NI, 1994) |
"Only recently available on the US market, levocetirizine has emerged as an effective new option in the treatment of chronic idiopathic urticaria (CIU)." | 8.85 | Levocetirizine for chronic idiopathic urticaria: a review. ( Ducharme, EE; Weinberg, JM, 2009) |
"H1-receptor inhibiting drugs, namely loratadine and cetirizine, were frequently used in treatment of chronic urticaria." | 7.80 | Effects of loratadine and cetirizine on serum levels of neuropeptides in patients with chronic urticaria. ( Başak, PY; Buyukbayram, HI; Erturan, I; Kazanoglu, OO; Vural, H, 2014) |
"We investigated the suitability of cetirizine HCl (cetirizine) for the initial treatment of chronic urticaria." | 7.74 | Evaluation of cetirizine hydrochloride-based therapeutic strategy for chronic urticaria. ( Ando, K; Azumi, T; Hirai, S; Kamiya, S; Kondo, T; Masaki, S; Mori, T; Nitta, Y; Sugiura, K; Suzuki, T; Tomita, Y; Usuda, T; Yokoi, T, 2008) |
"Treating chronic idiopathic urticaria with levocetirizine is a dominant strategy for society since it is more effective (in terms of pruritus-free days gained) and less costly than placebo." | 7.73 | Cost effectiveness of levocetirizine in chronic idiopathic urticaria : a pooled analysis of two randomised controlled trials. ( Demarteau, N; Kapp, A, 2006) |
"To determine if 6 weeks of therapy with levocetirizine 5 mg once daily would also induce any decrease in serum levels of intercellular adhesion molecule-1, vascular cell adhesion molecule-1, endothelial leucocyte adhesion molecule-1 (ELAM-1) or P-selectin in subjects with CU and chronic autoimmune urticaria." | 7.73 | Cellular adhesion molecules in chronic urticaria: modulation of serum levels occurs during levocetirizine treatment. ( Caproni, M; Del Bianco, E; Fabbri, P; Giomi, B; Torchia, D; Volpi, W, 2006) |
"By using capsaicin cough sensitivity as the basis for grouping the study subjects, we divided the patients into 2 groups: an increased cough sensitivity group (ICS, C5 <32 mumol/L) and a normal cough sensitivity (NCS) group." | 7.72 | Elevated substance P levels in nasal lavage fluids from patients with chronic nonproductive cough and increased cough sensitivity to inhaled capsaicin. ( Cho, YS; Lee, CK; Moon, HB; Park, SY; Yoo, B, 2003) |
"The paradoxical acute exacerbation of pre-existing chronic idiopathic urticaria accompanied by intense generalized pruritus, facial oedema, and dyspnoea in a 36-year-old-woman 3-4 h after a single oral dose of 10 mg cetirizine (Zyrtec tablets), suggested the presence of an underlying intolerance reaction." | 7.71 | Urticarial intolerance reaction to cetirizine. ( Damveld, B; Marsch, WC; Schröter, S, 2002) |
"The effects of oral administration of the antihistamine cetirizine on the weal and flare caused by intradermal injection of platelet activating factor (PAF-acether), kallikrein, histamine and the patient's own serum were investigated in 10 patients with chronic urticaria." | 7.68 | Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria. ( Juhlin, L; Rihoux, JP, 1990) |
"Bilastine is a recently introduced, non-sedative H1-antihistamine for its treatment." | 6.94 | Effectiveness, safety, and tolerability of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic spontaneous urticaria: A double-blind, parallel group, randomized controlled trial. ( Biswas, D; Chowdhury, SN; Das, A; Ghosh, S; Podder, I; Sengupta, S, 2020) |
"Levocetirizine was found to be more efficacious than rupatadine in CIU patients, but both drugs caused mild sedation." | 6.80 | Levocetirizine and rupatadine in chronic idiopathic urticaria. ( Badyal, DK; Johnson, M; Kwatra, G; Thomas, EA, 2015) |
"Olopatadine is a safe and more effective alternative to levocetirizine in the treatment of CU." | 6.78 | Olopatadine versus levocetirizine in chronic urticaria: an observer-blind, randomized, controlled trial of effectiveness and safety. ( Bagchi, C; Chaudhuri, A; Das, NK; Hazra, A; Islam, CN; Sil, A; Tripathi, SK, 2013) |
"Chronic Idiopathic Urticaria is difficult to treat due to its persistent debilitating symptoms." | 6.76 | Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety. ( Ahmed, I; Goud, P; Jaida, J; Maiti, R; Palani, A; Raghavendra, BN, 2011) |
"Chronic urticaria was related to the immune unbalance of body." | 6.73 | [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. ( Fang, ZD; Jin, CY; Wang, DL, 2008) |
"Levocetirizine is an antihistamine from the latest generation approved for CIU." | 6.72 | Levocetirizine is an effective treatment in patients suffering from chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled, parallel, multicenter study. ( Kapp, A; Pichler, WJ, 2006) |
"Cetirizine is a new H1 antagonist with potent inhibitory action against the infiltration of eosinophils into involved tissue, thereby affecting the late-phase reaction." | 6.38 | Cetirizine: a new H1 antagonist with antieosinophilic activity in chronic urticaria. ( Townley, RG, 1991) |
"Recently, several authors have suggested an off-label increase of antihistamine dosage should be given to patients with chronic urticaria (CU) not responding to the usual, recommended doses, in order to gain better control of the disease." | 5.34 | Chronic unremitting urticaria: is the use of antihistamines above the licensed dose effective? A preliminary study of cetirizine at licensed and above-licensed doses. ( Asero, R, 2007) |
"Combination of cetirizine with ranitidine was not more effective than cetirizine alone in chronic urticaria." | 5.20 | Safety and efficacy of cetirizine versus cetirizine plus ranitidine in chronic urticaria: Double-blind randomized placebo-controlled study. ( Bonilla-Lopez, S; Guevara-Gutierrez, E; Hernández-Arana, S; Tlacuilo-Parra, A, 2015) |
"Cetirizine is commonly used in the treatment of urticaria." | 5.19 | Clinical effectiveness and safety of cetirizine versus rupatadine in chronic spontaneous urticaria: a randomized, double-blind, 6-week trial. ( Dakhale, GN; Hiware, SK; Mahatme, MS; Mishra, DB; Mukhi, JI; Salve, AM; Shinde, AT, 2014) |
"Many physicians believe that the most effective way to treat chronic urticaria is to take a nonsedating second-generation H1 -antihistamine in the morning and a sedating first-generation H1 -antihistamine, usually hydroxyzine, at night to enhance sleep." | 5.19 | Night-time sedating H1 -antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial. ( Church, MK; Dimitrov, V; Gugutkova, M; Kralimarkova, T; Lazarova, C; Popov, TA; Staevska, M; Zuberbier, T, 2014) |
"Levocetirizine led to a significantly greater decrease in pruritus severity than desloratadine over the first treatment week; mean pruritus severity scores of 1." | 5.14 | Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients. ( Finlay, AY; Guillet, G; Hauptmann, P; Jian, AM; Kapp, A; Maurer, M; Potter, PC, 2009) |
"Bilastine is a novel nonsedative H(1)-receptor antagonist, which may be used for the symptomatic treatment of chronic idiopathic urticaria (CU)." | 5.14 | Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study. ( Antépara, I; Bogacka, E; Jáuregui, I; Medina, I; Oanta, A; Uhl, P; Valiente, R; Wesel, F; Zuberbier, T, 2010) |
"Eighty tertiary referral patients with chronic urticaria (age range, 19-67 years) were randomized for double-blind treatment with levocetirizine or desloratadine (40/40)." | 5.14 | The effectiveness of levocetirizine and desloratadine in up to 4 times conventional doses in difficult-to-treat urticaria. ( Church, DS; Church, MK; Dimitrov, V; Kraeva, S; Kralimarkova, T; Lazarova, C; Popov, TA; Popova, D; Staevska, M, 2010) |
"To determine whether levocetirizine is efficacious in the treatment of chronic idiopathic urticaria." | 5.12 | Levocetirizine in the treatment of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study. ( Barra, L; Colanardi, MC; Ferrannini, A; Nettis, E; Tursi, A; Vacca, A, 2006) |
"A 4-week randomized, double-blind safety and efficacy study was conducted to compare the safety and efficacy of cetirizine, doxepine, and hydroxyzine 5 in the treatment of chronic pruritus due to sulfur mustard." | 5.12 | Cetirizine, doxepine, and hydroxyzine in the treatment of pruritus due to sulfur mustard: a randomized clinical trial. ( Davoudi, SM; Keshavarz, S; Sadr, B; Shohrati, M; Tajik, A, 2007) |
"A double-blinded, placebo-controlled trial comparing cetirizine 10 mg daily in combination with zafirlukast 20 mg twice a day versus cetirizine 10 mg daily and placebo was conducted to determine whether subjects with chronic urticaria benefit from add-on therapy with a leukotriene-modifying agent." | 5.11 | The addition of zafirlukast to cetirizine improves the treatment of chronic urticaria in patients with positive autologous serum skin test results. ( Bagenstose, SE; Bernstein, JA; Levin, L, 2004) |
"The results of the present study suggest that cetirizine may represent an effective and safe pharmacologic therapy for chronic urticaria in preschool children." | 5.09 | Double-blind multicenter study on the efficacy and tolerability of cetirizine compared with oxatomide in chronic idiopathic urticaria in preschool children. ( Barberio, G; Corrias, A; Grimaldi, I; La Rosa, M; Leonardi, S; Marchese, G; Oggiano, N, 2001) |
"The results of this comparative study demonstrate that montelukast orally administered once a day is very effective for the treatment of cutaneous symptoms in patients with chronic urticaria due to food additives and/or ASA." | 5.09 | Efficacy of leukotriene receptor antagonist in chronic urticaria. A double-blind, placebo-controlled comparison of treatment with montelukast and cetirizine in patients with chronic urticaria with intolerance to food additive and/or acetylsalicylic acid. ( Corrocher, R; Di Lorenzo, G; Pacor, ML, 2001) |
"In this study co-administration of hydroxyzine with cimetidine resulted in significantly increased serum hydroxyzine concentrations and increased wheal and flare suppression, thus confirming the rationale for a trial of concomitant administration of these medications in some patients with chronic urticaria unresponsive to treatment with an H1-antagonist alone." | 5.08 | Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria. ( Simons, FE; Simons, KJ; Sussman, GL, 1995) |
"Cetirizine 10 mg once daily was equivalent to hydroxyzine 25 mg tid in controlling the symptoms of patients with chronic urticaria, as assessed by patient and investigator evaluations." | 5.08 | Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria. ( Breneman, DL, 1996) |
"Clinical trials of a new histamine H1-blocker of the III generation zyrtec (cetirizine) manufactured in Belgium (UCB) demonstrated its high efficacy in pollenosis and chronic idiopathic urticaria." | 5.07 | [The efficacy of the Zirtek (cetirizine) preparation in chronic recurrent urticaria and seasonal allergic rhinitis]. ( Androsov, VN; Belostotskaia, OI; Il'ina, NI, 1994) |
"In a 20-d, double-blind, randomized, parallel study, the efficacy of cetirizine and terfenadine was compared in 30 patients with chronic idiopathic urticaria." | 5.07 | A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria. ( Andri, G; Andri, L; Betteli, C; Givanni, S; Lombardi, C; Mezzelani, P; Senna, GE, 1993) |
"Our randomised study in parallel groups, double-blind double placebo, has compared the efficacy, onset of action and safety of terfenadine and cetirizine in chronic idiopathic urticaria." | 5.07 | [Double-blind comparative study of terfenadine and cetirizine in chronic idiopathic urticaria]. ( Bloom, M; Danglas, P; Hantzperg, M; Lambert, D, 1993) |
"The efficacy of cetirizine dihydrochloride, a new H1-antagonist claimed to have minimal sedative property was evaluated in 28 patients with chronic idiopathic urticaria." | 5.07 | Cetirizine vs placebo in chronic idiopathic urticaria--a double blind randomised cross-over study. ( Goh, CL; Lim, J; Wong, WK, 1991) |
"Only recently available on the US market, levocetirizine has emerged as an effective new option in the treatment of chronic idiopathic urticaria (CIU)." | 4.85 | Levocetirizine for chronic idiopathic urticaria: a review. ( Ducharme, EE; Weinberg, JM, 2009) |
"H1-receptor inhibiting drugs, namely loratadine and cetirizine, were frequently used in treatment of chronic urticaria." | 3.80 | Effects of loratadine and cetirizine on serum levels of neuropeptides in patients with chronic urticaria. ( Başak, PY; Buyukbayram, HI; Erturan, I; Kazanoglu, OO; Vural, H, 2014) |
" A 23-month-old male with a history of chronic otitis media was prescribed cetirizine 2." | 3.76 | Use of cetirizine in a 23-month-old male causes insomnia. ( Jones, CE; Jones, MC, 2010) |
"We investigated the suitability of cetirizine HCl (cetirizine) for the initial treatment of chronic urticaria." | 3.74 | Evaluation of cetirizine hydrochloride-based therapeutic strategy for chronic urticaria. ( Ando, K; Azumi, T; Hirai, S; Kamiya, S; Kondo, T; Masaki, S; Mori, T; Nitta, Y; Sugiura, K; Suzuki, T; Tomita, Y; Usuda, T; Yokoi, T, 2008) |
"Treating chronic idiopathic urticaria with levocetirizine is a dominant strategy for society since it is more effective (in terms of pruritus-free days gained) and less costly than placebo." | 3.73 | Cost effectiveness of levocetirizine in chronic idiopathic urticaria : a pooled analysis of two randomised controlled trials. ( Demarteau, N; Kapp, A, 2006) |
"To determine if 6 weeks of therapy with levocetirizine 5 mg once daily would also induce any decrease in serum levels of intercellular adhesion molecule-1, vascular cell adhesion molecule-1, endothelial leucocyte adhesion molecule-1 (ELAM-1) or P-selectin in subjects with CU and chronic autoimmune urticaria." | 3.73 | Cellular adhesion molecules in chronic urticaria: modulation of serum levels occurs during levocetirizine treatment. ( Caproni, M; Del Bianco, E; Fabbri, P; Giomi, B; Torchia, D; Volpi, W, 2006) |
"By using capsaicin cough sensitivity as the basis for grouping the study subjects, we divided the patients into 2 groups: an increased cough sensitivity group (ICS, C5 <32 mumol/L) and a normal cough sensitivity (NCS) group." | 3.72 | Elevated substance P levels in nasal lavage fluids from patients with chronic nonproductive cough and increased cough sensitivity to inhaled capsaicin. ( Cho, YS; Lee, CK; Moon, HB; Park, SY; Yoo, B, 2003) |
"The paradoxical acute exacerbation of pre-existing chronic idiopathic urticaria accompanied by intense generalized pruritus, facial oedema, and dyspnoea in a 36-year-old-woman 3-4 h after a single oral dose of 10 mg cetirizine (Zyrtec tablets), suggested the presence of an underlying intolerance reaction." | 3.71 | Urticarial intolerance reaction to cetirizine. ( Damveld, B; Marsch, WC; Schröter, S, 2002) |
"The effects of oral administration of the antihistamine cetirizine on the weal and flare caused by intradermal injection of platelet activating factor (PAF-acether), kallikrein, histamine and the patient's own serum were investigated in 10 patients with chronic urticaria." | 3.68 | Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria. ( Juhlin, L; Rihoux, JP, 1990) |
"Bilastine is a recently introduced, non-sedative H1-antihistamine for its treatment." | 2.94 | Effectiveness, safety, and tolerability of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic spontaneous urticaria: A double-blind, parallel group, randomized controlled trial. ( Biswas, D; Chowdhury, SN; Das, A; Ghosh, S; Podder, I; Sengupta, S, 2020) |
"Levocetirizine was found to be more efficacious than rupatadine in CIU patients, but both drugs caused mild sedation." | 2.80 | Levocetirizine and rupatadine in chronic idiopathic urticaria. ( Badyal, DK; Johnson, M; Kwatra, G; Thomas, EA, 2015) |
"Olopatadine is a safe and more effective alternative to levocetirizine in the treatment of CU." | 2.78 | Olopatadine versus levocetirizine in chronic urticaria: an observer-blind, randomized, controlled trial of effectiveness and safety. ( Bagchi, C; Chaudhuri, A; Das, NK; Hazra, A; Islam, CN; Sil, A; Tripathi, SK, 2013) |
"Chronic Idiopathic Urticaria is difficult to treat due to its persistent debilitating symptoms." | 2.76 | Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety. ( Ahmed, I; Goud, P; Jaida, J; Maiti, R; Palani, A; Raghavendra, BN, 2011) |
" Secondary end-points were the rate of control of chronic cough at each step of therapy, the duration of treatment required, changes in cough symptom score, health-related quality of life and possible adverse effects." | 2.75 | Efficacy and safety of modified sequential three-step empirical therapy for chronic cough. ( Li, X; Liang, S; Liu, B; Lü, H; Qiu, Z; Wang, L; Wang, Y; Wei, W; Yu, L, 2010) |
"Chronic urticaria was related to the immune unbalance of body." | 2.73 | [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. ( Fang, ZD; Jin, CY; Wang, DL, 2008) |
"Levocetirizine is an antihistamine from the latest generation approved for CIU." | 2.72 | Levocetirizine is an effective treatment in patients suffering from chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled, parallel, multicenter study. ( Kapp, A; Pichler, WJ, 2006) |
"Levocetirizine has several pharmacokinetic properties that are desirable for an antihistamine providing a combination of both potency and safety." | 2.47 | Pharmacokinetic evaluation of levocetirizine. ( Ferrer, M, 2011) |
"Cetirizine is a new H1 antagonist with potent inhibitory action against the infiltration of eosinophils into involved tissue, thereby affecting the late-phase reaction." | 2.38 | Cetirizine: a new H1 antagonist with antieosinophilic activity in chronic urticaria. ( Townley, RG, 1991) |
" The first-generation H(1)-antihistamines are associated with marked adverse effects such as sedation, sleepiness/drowsiness as well as difficulties in learning and cognitive processing; thus, they are recommended for limited or discontinued use in children with AR or CIU." | 1.37 | Evidence for clinical safety, efficacy, and parent and physician perceptions of levocetirizine for the treatment of children with allergic disease. ( Kurzawa, R; Pampura, AN; Papadopoulos, NG; Spičák, V, 2011) |
"Recently, several authors have suggested an off-label increase of antihistamine dosage should be given to patients with chronic urticaria (CU) not responding to the usual, recommended doses, in order to gain better control of the disease." | 1.34 | Chronic unremitting urticaria: is the use of antihistamines above the licensed dose effective? A preliminary study of cetirizine at licensed and above-licensed doses. ( Asero, R, 2007) |
Research
Studies (74)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.35) | 18.7374 |
1990's | 19 (25.68) | 18.2507 |
2000's | 28 (37.84) | 29.6817 |
2010's | 24 (32.43) | 24.3611 |
2020's | 2 (2.70) | 2.80 |
Authors
Authors | Studies |
---|---|
Podder, I | 1 |
Das, A | 1 |
Ghosh, S | 1 |
Biswas, D | 1 |
Sengupta, S | 1 |
Chowdhury, SN | 1 |
Shah, B | 1 |
De, A | 1 |
Sarda, A | 1 |
Kochhar, AM | 1 |
Dhoot, D | 1 |
Deshmukh, G | 1 |
Barkate, H | 1 |
Kolkhir, P | 1 |
Pogorelov, D | 1 |
Olisova, O | 1 |
Iweala, OI | 1 |
Copenhaver, C | 1 |
Wu, EY | 1 |
Moran, TP | 1 |
Yan, M | 1 |
Ye, F | 1 |
Zhang, Y | 1 |
Cai, X | 1 |
Fu, Y | 1 |
Yang, X | 1 |
Dakhale, GN | 1 |
Shinde, AT | 1 |
Mahatme, MS | 1 |
Hiware, SK | 1 |
Mishra, DB | 1 |
Mukhi, JI | 1 |
Salve, AM | 1 |
Staevska, M | 2 |
Gugutkova, M | 1 |
Lazarova, C | 2 |
Kralimarkova, T | 2 |
Dimitrov, V | 2 |
Zuberbier, T | 2 |
Church, MK | 2 |
Popov, TA | 2 |
Rorie, A | 1 |
Goldner, WS | 1 |
Lyden, E | 1 |
Poole, JA | 1 |
Başak, PY | 1 |
Vural, H | 1 |
Kazanoglu, OO | 1 |
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Hong, JB | 2 |
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Clinical Trials (4)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
The Role of Vitamin D in Chronic Urticaria and Angioedema Treatment[NCT01371877] | 42 participants (Actual) | Interventional | 2011-11-01 | Completed | |||
Double-blind, Randomised, Placebo-controlled, Phase III Study Comparing the Efficacy and Safety of Bilastine 20 mg Once Daily and Levocetirizine 5 mg for the Treatment of Chronic Idiopathic Urticaria[NCT00421109] | Phase 3 | 522 participants (Actual) | Interventional | 2006-07-31 | Completed | ||
A Multicentre, International, Adaptive, Open-label, Repeated Administration Pharmacokinetic Study of Bilastine in Children From 2 to <12 Years of Age With Allergic Rhinoconjunctivitis or Chronic Urticaria[NCT01081574] | Phase 1/Phase 2 | 36 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
Efficacy and Safety of 20 mg Levocetirizine and 15 mg Levocetirizine + 50 mg Bed-Time Hydroxyzine in Severe Chronic Urticaria in Adults: a Pilot, Randomized, Double-blind, Cross-over and Parallel, Active-controlled, Single-centre Study[NCT01250652] | Phase 4 | 24 participants (Actual) | Interventional | 2011-03-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trial Outcomes
Number of Participants With Adverse Events
Unit of Measure is Safety and Tolerability. The number of participants with adverse events will be compared between the groups using the independent sample t-test (assuming the distribution is normal). (NCT01371877)
Timeframe: 3 month study trial
Intervention | participants (Number) |
---|---|
High Dose Vitamin D | 0 |
Low Dose Vitamin D | 0 |
Medication Usage
The Unit of Measure is Efficacy. The primary outcome of this study is to determine if vitamin D supplementation reduces the medication usage in subjects with CUA. Thus, for the outcome of reduction in pills, at 12 weeks, subjects whose pill usage decreases by 2 or more pills per day will be classified as improved. Subjects whose pill consumption did not change or increased will be classified as unchanged. (NCT01371877)
Timeframe: 12 week intervention
Intervention | number of pills/day (Mean) | |
---|---|---|
Baseline medication usage | 3 month medication usage | |
High Dose Vitamin D | 2.8 | 2.0 |
Low Dose Vitamin D | 4.6 | 4.9 |
Total Urticaria Severity Score at 3 Months
The Unit of Measure is Efficacy. The Total Urticaria Severity Score (USS) ranges from 0 to 93, higher scores = worse symptoms. This secondary outcome of this study is to determine if high dose vitamin D supplementation improves the urticaria severity score (USS). The change in USS will be compared between the groups using the independent sample t-test (assuming the distribution is normal). Logistic regression and multiple linear regression will be used to adjust for possible confounders. (NCT01371877)
Timeframe: 3 month intervention
Intervention | units on a scale (Mean) | ||
---|---|---|---|
Baseline Total Urticaria Score | 1 week Total Urticaria Score | 3 month Total Urticaria Score | |
High Dose Vitamin D | 41.14 | 25.48 | 15.0 |
Low Dose Vitamin D | 40.1 | 29.24 | 24.1 |
Reviews
8 reviews available for cetirizine and Chronic Disease
Article | Year |
---|---|
Levocetirizine for chronic idiopathic urticaria: a review.
Topics: Cetirizine; Chronic Disease; Cost-Benefit Analysis; Histamine H1 Antagonists, Non-Sedating; Humans; | 2009 |
Pharmacokinetic evaluation of levocetirizine.
Topics: Cetirizine; Chronic Disease; Drug Evaluation; Histamine H1 Antagonists, Non-Sedating; Humans; Random | 2011 |
Clinical studies with cetirizine in allergic rhinitis and chronic urticaria.
Topics: Cetirizine; Chronic Disease; Clinical Trials as Topic; Humans; Rhinitis, Allergic, Perennial; Rhinit | 1995 |
Allergy and sinusitis.
Topics: Allergens; Anti-Allergic Agents; Anti-Inflammatory Agents; Beclomethasone; Blood Proteins; Cetirizin | 1997 |
Early treatment of the atopic child.
Topics: Anti-Allergic Agents; Asthma; Cetirizine; Child, Preschool; Chronic Disease; Clinical Trials as Topi | 1997 |
[Pharmacological and clinical properties of cetirizine hydrochloride].
Topics: Animals; Anti-Allergic Agents; Cetirizine; Chemotaxis; Chronic Disease; Electrocardiography; Eosinop | 2000 |
Cetirizine: a new H1 antagonist with antieosinophilic activity in chronic urticaria.
Topics: Cetirizine; Chronic Disease; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzine; Urticaria | 1991 |
Cetirizine. A review of its pharmacological properties and clinical potential in allergic rhinitis, pollen-induced asthma, and chronic urticaria.
Topics: Animals; Asthma; Cetirizine; Chronic Disease; Histamine H1 Antagonists; Humans; Hydroxyzine; Pollen; | 1990 |
Trials
42 trials available for cetirizine and Chronic Disease
Article | Year |
---|---|
Effectiveness, safety, and tolerability of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic spontaneous urticaria: A double-blind, parallel group, randomized controlled trial.
Topics: Benzimidazoles; Cetirizine; Chronic Disease; Chronic Urticaria; Double-Blind Method; Histamine H1 An | 2020 |
Optimization model research on efficacy in treatment of chronic urticaria by Chinese and Western medicine based on a genetic algorithm.
Topics: Algorithms; Case-Control Studies; Cetirizine; Chronic Disease; Drugs, Chinese Herbal; Humans; Urtica | 2013 |
Clinical effectiveness and safety of cetirizine versus rupatadine in chronic spontaneous urticaria: a randomized, double-blind, 6-week trial.
Topics: Adult; Cetirizine; Chronic Disease; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antago | 2014 |
Night-time sedating H1 -antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Cross-Over Studies; Double-Blind Method; Drug Administrati | 2014 |
Beneficial role for supplemental vitamin D3 treatment in chronic urticaria: a randomized study.
Topics: Acetates; Adult; Aged; Cetirizine; Cholecalciferol; Chronic Disease; Cyclopropanes; Dietary Suppleme | 2014 |
Levocetirizine and rupatadine in chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Child; Chronic Disease; Cyproheptadine; Female; Histamine H1 An | 2015 |
Safety and efficacy of cetirizine versus cetirizine plus ranitidine in chronic urticaria: Double-blind randomized placebo-controlled study.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonists, Non | 2015 |
Effects of cetirizine in dogs with chronic atopic dermatitis: a randomized, double blind, placebo-controlled trial.
Topics: Animals; Cetirizine; Chronic Disease; Dermatitis, Atopic; Dog Diseases; Dogs; Double-Blind Method; F | 2016 |
An open-label prospective clinical study to assess the efficacy of increasing levocetirizine dose up to four times in chronic spontaneous urticaria not controlled with standard dose.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Disorders of Excessive Somnolence; Dose-Respon | 2017 |
[Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood].
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Drug Therapy, Combination; Drugs, Chinese Herbal; Fe | 2008 |
Quality of life in patients with persistent allergic rhinitis treated with montelukast alone or in combination with levocetirizine or desloratadine.
Topics: Acetates; Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Cross-Over Studies; Cyclopropanes; D | 2008 |
Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients.
Topics: Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Hu | 2009 |
Efficacy of leukotriene receptor antagonist with an anti-H1 receptor antagonist for treatment of chronic idiopathic urticaria.
Topics: Acetates; Adolescent; Adult; Cetirizine; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; | 2009 |
Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Area Under Curve; Benzimidazoles; Cetirizine; Chronic Disease; Double-Blind | 2010 |
Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Area Under Curve; Benzimidazoles; Cetirizine; Chronic Disease; Double-Blind | 2010 |
Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Area Under Curve; Benzimidazoles; Cetirizine; Chronic Disease; Double-Blind | 2010 |
Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Area Under Curve; Benzimidazoles; Cetirizine; Chronic Disease; Double-Blind | 2010 |
The effectiveness of levocetirizine and desloratadine in up to 4 times conventional doses in difficult-to-treat urticaria.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Fem | 2010 |
Efficacy and safety of modified sequential three-step empirical therapy for chronic cough.
Topics: Adult; Aminophylline; Antitussive Agents; Budesonide; Cetirizine; Chlorpheniramine; Chronic Disease; | 2010 |
Clinical observation on the treatment of chronic urticaria with total glucosides of paeony capsule combined with citirizine.
Topics: Adolescent; Adult; Anti-Allergic Agents; Capsules; Cetirizine; Chronic Disease; Drug Therapy, Combin | 2010 |
A randomized, double-blind, active-controlled, parallel-group pilot study to compare the efficacy and sedative effects of desloratadine 5 mg with levocetirizine 5 mg in the treatment of chronic idiopathic urticaria.
Topics: Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Hu | 2010 |
Efficacy of Tripterygium hypoglaucum Hutch in adults with chronic urticaria.
Topics: Adult; Antipruritics; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagon | 2011 |
Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety.
Topics: Adolescent; Adult; Cetirizine; Child; Chronic Disease; Cyproheptadine; Female; Follow-Up Studies; Hi | 2011 |
Olopatadine versus levocetirizine in chronic urticaria: an observer-blind, randomized, controlled trial of effectiveness and safety.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Cetirizine; Chronic Dise | 2013 |
The addition of zafirlukast to cetirizine improves the treatment of chronic urticaria in patients with positive autologous serum skin test results.
Topics: Adult; Autoantigens; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagoni | 2004 |
Levocetirizine: the allergist's arsenal grows larger.
Topics: Allergy and Immunology; Cetirizine; Chronic Disease; Clinical Trials, Phase III as Topic; Double-Bli | 2004 |
Levocetirizine in the treatment of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Female; | 2006 |
Levocetirizine is an effective treatment in patients suffering from chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled, parallel, multicenter study.
Topics: Adult; Cetirizine; Chronic Disease; Double-Blind Method; Efficiency; Female; Germany; Histamine H1 A | 2006 |
Comparative efficacy of cetirizine and levocetirizine in chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists, Non-Sedating | 2007 |
Increasing the dose of cetirizine may lead to better control of chronic idiopathic urticaria: an open study of 21 patients.
Topics: Adult; Cetirizine; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; | 2007 |
Cetirizine, doxepine, and hydroxyzine in the treatment of pruritus due to sulfur mustard: a randomized clinical trial.
Topics: Administration, Oral; Adult; Antipruritics; Cetirizine; Chemical Warfare Agents; Chronic Disease; Do | 2007 |
Treatment of chronic urticaria with narrowband ultraviolet B phototherapy: a randomized controlled trial.
Topics: Adult; Cetirizine; Chronic Disease; Combined Modality Therapy; Female; Histamine H1 Antagonists, Non | 2008 |
Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Cimetidine; Double-Blind Method; Drug Combinat | 1995 |
[The efficacy of the Zirtek (cetirizine) preparation in chronic recurrent urticaria and seasonal allergic rhinitis].
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Drug Therapy, Combination; Female; Humans; Male; Mid | 1994 |
[Double-blind comparative study of terfenadine and cetirizine in chronic idiopathic urticaria].
Topics: Adolescent; Adult; Cetirizine; Child; Chronic Disease; Double-Blind Method; Female; Humans; Male; Mi | 1993 |
A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria.
Topics: Adult; Cetirizine; Chronic Disease; Double-Blind Method; Humans; Terfenadine; Urticaria | 1993 |
Cetirizine: a new therapeutic alternative for chronic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Male | 1996 |
Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria.
Topics: Adult; Cetirizine; Chronic Disease; Double-Blind Method; Drug Tolerance; Female; Humans; Hydroxyzine | 1996 |
[The efficacy of cetirizine in the treatment of perennial allergic rhinitis].
Topics: Adult; Anti-Allergic Agents; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; | 1999 |
Stanozolol in chronic urticaria: a double blind, placebo controlled trial.
Topics: Adolescent; Adult; Anabolic Agents; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histam | 2001 |
Double-blind multicenter study on the efficacy and tolerability of cetirizine compared with oxatomide in chronic idiopathic urticaria in preschool children.
Topics: Anti-Allergic Agents; Cetirizine; Child, Preschool; Chronic Disease; Double-Blind Method; Drug Toler | 2001 |
Efficacy of leukotriene receptor antagonist in chronic urticaria. A double-blind, placebo-controlled comparison of treatment with montelukast and cetirizine in patients with chronic urticaria with intolerance to food additive and/or acetylsalicylic acid.
Topics: Acetates; Adolescent; Adult; Aged; Aspirin; Cetirizine; Chronic Disease; Cyclopropanes; Double-Blind | 2001 |
Cetirizine vs placebo in chronic idiopathic urticaria--a double blind randomised cross-over study.
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonist | 1991 |
Comparison of cetirizine and terfenadine in the treatment of chronic idiopathic urticaria.
Topics: Benzhydryl Compounds; Cetirizine; Chronic Disease; Double-Blind Method; Histamine H1 Antagonists; Hu | 1990 |
[Importance of Zyrtec in the treatment of chronic urticaria and allergic rhinopathies apropos of 1168 cases seen by hospital practitioners].
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Hydroxyzin | 1989 |
Other Studies
24 other studies available for cetirizine and Chronic Disease
Article | Year |
---|---|
Effect of bilastine on chronic spontaneous urticaria refractory to levocetrizine: Real world experience in India.
Topics: Benzimidazoles; Cetirizine; Chronic Disease; Chronic Urticaria; Humans; India; Piperidines; Urticari | 2021 |
CRP, D-dimer, fibrinogen and ESR as predictive markers of response to standard doses of levocetirizine in patients with chronic spontaneous urticaria.
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Sedimentation; C-Reactive Protein; Cetirizine; Chronic Di | 2017 |
Hydroxychloroquine as a steroid-sparing agent in an infant with chronic urticaria.
Topics: Acetates; Anti-Inflammatory Agents; Antimalarials; Cetirizine; Chronic Disease; Cyclopropanes; Diphe | 2018 |
Effects of loratadine and cetirizine on serum levels of neuropeptides in patients with chronic urticaria.
Topics: Adolescent; Adult; Calcitonin Gene-Related Peptide; Cetirizine; Chronic Disease; Female; Histamine H | 2014 |
Evaluation of cetirizine hydrochloride-based therapeutic strategy for chronic urticaria.
Topics: Adult; Aged; Aged, 80 and over; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists, Non-S | 2008 |
Heparin and tranexamic Acid therapy may be effective in treatment-resistant chronic urticaria with elevated d-dimer: a pilot study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Cetirizine; Chr | 2010 |
Use of cetirizine in a 23-month-old male causes insomnia.
Topics: Anti-Allergic Agents; Cetirizine; Chronic Disease; Humans; Infant; Male; Otitis Media; Sleep Initiat | 2010 |
Evidence for clinical safety, efficacy, and parent and physician perceptions of levocetirizine for the treatment of children with allergic disease.
Topics: Adult; Anti-Allergic Agents; Attitude of Health Personnel; Cetirizine; Child; Child, Preschool; Chro | 2011 |
Chronic idiopathic urticaria in Taiwan: a clinical study of demographics, aggravating factors, laboratory findings, serum autoreactivity and treatment response.
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Loratadine | 2011 |
Chronic urticaria and angioedema.
Topics: Angioedema; Cetirizine; Chronic Disease; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine | 2002 |
Evaluation of the efficacy of antihistamines using human monocyte-derived dendritic cells stimulated with histamine.
Topics: Adolescent; Adult; Antigens, CD; B7-2 Antigen; Cetirizine; Chronic Disease; Cimetidine; Dendritic Ce | 2003 |
Elevated substance P levels in nasal lavage fluids from patients with chronic nonproductive cough and increased cough sensitivity to inhaled capsaicin.
Topics: Administration, Inhalation; Adult; Capsaicin; Case-Control Studies; Cetirizine; Chronic Disease; Cou | 2003 |
Mastocytic enterocolitis: increased mucosal mast cells in chronic intractable diarrhea.
Topics: Adult; Aged; Cell Count; Cetirizine; Chronic Disease; Colon; Diarrhea; Drug Therapy, Combination; Du | 2006 |
Chronic unremitting urticaria: is the use of antihistamines above the licensed dose effective? A preliminary study of cetirizine at licensed and above-licensed doses.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Drug Administration Schedule; Female; Histamine H1 Antagon | 2007 |
Cellular adhesion molecules in chronic urticaria: modulation of serum levels occurs during levocetirizine treatment.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; E-Selectin; Enzyme-Linked Immunosorbent Assay; | 2006 |
Cost effectiveness of levocetirizine in chronic idiopathic urticaria : a pooled analysis of two randomised controlled trials.
Topics: Adult; Anti-Allergic Agents; Cetirizine; Chronic Disease; Cost-Benefit Analysis; Female; Health Care | 2006 |
Acute episode or chronic problem?
Topics: Acute Disease; Angioedema; Cellulitis; Cetirizine; Chronic Disease; Dermatitis, Contact; Diagnosis, | 2007 |
New hay fever, hives treatment approved.
Topics: Cetirizine; Chronic Disease; Clinical Trials as Topic; Histamine H1 Antagonists, Non-Sedating; Human | 2007 |
[Delayed-type pressure urticaria].
Topics: Adult; Angioedema; Anti-Allergic Agents; Cetirizine; Chronic Disease; Humans; Male; Urticaria | 1995 |
Fexofenadine: new preparation. Terfenadine, without cardiotoxicity.
Topics: Cetirizine; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Histamine Antagonists; Human | 1999 |
Urticarial intolerance reaction to cetirizine.
Topics: Acute Disease; Adult; Anti-Allergic Agents; Cetirizine; Chronic Disease; Drug Eruptions; Female; His | 2002 |
[Effect of cetirizine, selective H1 antagonist of histamine on skin and bronchial reactivity and cellular histamine release in allergic diseases].
Topics: Asthma; Bronchial Provocation Tests; Cetirizine; Chronic Disease; Histamine; Humans; Neutrophils; Rh | 1992 |
Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria.
Topics: Adult; Blood Transfusion, Autologous; Cetirizine; Chronic Disease; Female; Histamine; Histamine H1 A | 1990 |
Late-phase cutaneous reactions to platelet activating factor and kallikrein in urticaria.
Topics: Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersens | 1990 |