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cetirizine and Bronchial Spasm

cetirizine has been researched along with Bronchial Spasm in 6 studies

Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.

Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.

Research Excerpts

ExcerptRelevanceReference
" To evaluate this oral drug's efficacy in treating asthma, we examined the bronchodilator effects of 5-, 10-, and 20-mg doses as well as the protective effects of these doses against histamine-provoked bronchospasm."9.06Cetirizine inhibition of histamine-induced bronchospasm. ( Brik, A; Gong, H; Tashkin, DP, 1987)
" To evaluate this oral drug's efficacy in treating asthma, we examined the bronchodilator effects of 5-, 10-, and 20-mg doses as well as the protective effects of these doses against histamine-provoked bronchospasm."5.06Cetirizine inhibition of histamine-induced bronchospasm. ( Brik, A; Gong, H; Tashkin, DP, 1987)
"In vivo antihistaminic activity experiments consisted of measurement of: inhibition of increase in capillary permeability and reduction in microvascular extravasation and bronchospasm in rats and guinea pigs induced by histamine and other inflammatory mediators; and protection against lethality induced by histamine and other inflammatory mediators in rats."3.73In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist. ( Berisa, A; Corcóstegui, R; Innerárity, A; Labeaga, L; Orjales, A, 2006)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alagarsamy, V1
Giridhar, R1
Yadav, MR2
Llupià, J1
Gras, J1
Llenas, J1
Corcóstegui, R1
Labeaga, L1
Innerárity, A1
Berisa, A1
Orjales, A1
Brik, A2
Tashkin, DP2
Gong, H2
Dauphinee, B1
Lee, E1

Trials

2 trials available for cetirizine and Bronchial Spasm

ArticleYear
Effect of cetirizine, a new histamine H1 antagonist, on airway dynamics and responsiveness to inhaled histamine in mild asthma.
    The Journal of allergy and clinical immunology, 1987, Volume: 80, Issue:1

    Topics: Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Spasm; Cetirizine; Dose-Response Relat

1987
Cetirizine inhibition of histamine-induced bronchospasm.
    Annals of allergy, 1987, Volume: 59, Issue:6 Pt 2

    Topics: Adult; Analysis of Variance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Ag

1987

Other Studies

4 other studies available for cetirizine and Bronchial Spasm

ArticleYear
Synthesis and pharmacological investigation of novel 1-substituted-4-phenyl-1,2,4-triazolo[4,3-a]quinazolin-5(4H)-ones as a new class of H1-antihistaminic agents.
    Bioorganic & medicinal chemistry letters, 2005, Apr-01, Volume: 15, Issue:7

    Topics: Animals; Bronchial Spasm; Chlorpheniramine; Cyclization; Guinea Pigs; Histamine H1 Antagonists; Hypn

2005
Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:2

    Topics: Aerosols; Airway Resistance; Algorithms; Animals; Anti-Allergic Agents; Bronchial Spasm; Butyropheno

2003
In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist.
    Drugs in R&D, 2006, Volume: 7, Issue:4

    Topics: Animals; Benzimidazoles; Bradykinin; Bronchial Spasm; Capillary Permeability; Cetirizine; Dermatitis

2006
Cetirizine--a new antihistamine.
    The Medical letter on drugs and therapeutics, 1996, Mar-15, Volume: 38, Issue:970

    Topics: Adolescent; Adult; Anti-Allergic Agents; Bronchial Spasm; Bronchodilator Agents; Cetirizine; Double-

1996