Page last updated: 2024-10-24

cetirizine and Bronchial Hyperreactivity

cetirizine has been researched along with Bronchial Hyperreactivity in 8 studies

Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.

Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.

Research Excerpts

ExcerptRelevanceReference
"Fifteen atopic asthmatics were randomized in double-blind, cross-over fashion to receive for 1 week either levocetirizine 5 mg or placebo."9.11Single and short-term dosing effects of levocetirizine on adenosine monophosphate bronchoprovocation in atopic asthma. ( Gray, RD; Lee, DK; Lipworth, BJ; Robb, FM; Soutar, PC; Wilson, AM, 2004)
"Cetirizine is a non-sedating H1 antihistamine which is effective in the treatment of allergic rhinitis and urticaria."6.68A comparison of the effects of oral cetirizine and inhaled beclomethasone on early and late asthmatic responses to allergen and the associated increase in airways hyperresponsiveness. ( Bentley, AM; De Vos, C; Durham, SR; Hanotte, F; Walker, S, 1996)
"Fifteen atopic asthmatics were randomized in double-blind, cross-over fashion to receive for 1 week either levocetirizine 5 mg or placebo."5.11Single and short-term dosing effects of levocetirizine on adenosine monophosphate bronchoprovocation in atopic asthma. ( Gray, RD; Lee, DK; Lipworth, BJ; Robb, FM; Soutar, PC; Wilson, AM, 2004)
"Cetirizine is a non-sedating H1 antihistamine which is effective in the treatment of allergic rhinitis and urticaria."2.68A comparison of the effects of oral cetirizine and inhaled beclomethasone on early and late asthmatic responses to allergen and the associated increase in airways hyperresponsiveness. ( Bentley, AM; De Vos, C; Durham, SR; Hanotte, F; Walker, S, 1996)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Delescluse, I1
Mace, H1
Adcock, JJ1
Magnan, A1
Lee, DK1
Gray, RD1
Wilson, AM1
Robb, FM1
Soutar, PC1
Lipworth, BJ1
Boichot, E1
Richard, MP1
Paubert-Braquet, M1
Bentley, AM1
Walker, S1
Hanotte, F1
De Vos, C1
Durham, SR1
Aubier, M2
Musoh, K1
Maeda, Y1
Tanaka, H1
Inagaki, N1
Nagai, H1
Neukirch, C1
Peiffer, C1
Melac, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Placebo Controlled Trial to Evaluate The Effects of Levocetirizine on Nasal Allergen Challenge And Adenosine Monophosphate Challenge In Patients With Intermittent and Persistent Allergic Rhinitis[NCT00679250]Phase 425 participants (Actual)Interventional2005-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for cetirizine and Bronchial Hyperreactivity

ArticleYear
Linking upper and lower airways.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1999, Volume: 83, Issue:5

    Topics: Adrenal Cortex Hormones; Bronchial Hyperreactivity; Cetirizine; Histamine H1 Antagonists; Humans; Rh

1999

Trials

3 trials available for cetirizine and Bronchial Hyperreactivity

ArticleYear
Single and short-term dosing effects of levocetirizine on adenosine monophosphate bronchoprovocation in atopic asthma.
    British journal of clinical pharmacology, 2004, Volume: 58, Issue:1

    Topics: Adenosine Monophosphate; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests

2004
A comparison of the effects of oral cetirizine and inhaled beclomethasone on early and late asthmatic responses to allergen and the associated increase in airways hyperresponsiveness.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1996, Volume: 26, Issue:8

    Topics: Administration, Inhalation; Administration, Oral; Adult; Allergens; Antigens, Dermatophagoides; Asth

1996
Effect of cetirizine on bronchial hyperresponsiveness in patients with seasonal allergic rhinitis and asthma.
    Allergy, 2001, Volume: 56, Issue:1

    Topics: Adult; Anti-Allergic Agents; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Cetirizin

2001

Other Studies

4 other studies available for cetirizine and Bronchial Hyperreactivity

ArticleYear
Inhibition of airway hyper-responsiveness by TRPV1 antagonists (SB-705498 and PF-04065463) in the unanaesthetized, ovalbumin-sensitized guinea pig.
    British journal of pharmacology, 2012, Volume: 166, Issue:6

    Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Allergens; Animals; Atropine; Bronchial Hyperreactiv

2012
[Respiratory allergies in the child and the adult].
    La Revue du praticien, 2004, Jan-31, Volume: 54, Issue:2

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Allergens; Anti-Allergic Ag

2004
Effect of cefadroxil on antigen-induced bronchial hyperresponsiveness and eosinophil accumulation in lung from sensitized guinea pigs.
    International archives of allergy and immunology, 1993, Volume: 102, Issue:1

    Topics: Acetylcholine; Aerosols; Animals; Bronchial Hyperreactivity; Cefadroxil; Cetirizine; Eosinophils; Gu

1993
Effect of a novel anti-allergic agent, HSR-609, on antigen-induced airway hyperresponsiveness in mice.
    Pharmacology, 2000, Volume: 61, Issue:2

    Topics: Acetylcholine; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Benzoxepins; Bronchial Hyper

2000