cetirizine has been researched along with Arrhythmia in 9 studies
Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 72-year-old woman with renal insufficiency who was taking oral pilsicainide (150 mg/d) complained of feeling faint 3 days after she was prescribed oral cetirizine (20 mg/d)." | 9.12 | Severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency: first case presentation showing competition for excretion via renal multidrug resistance protein 1 and organic cation transporter 2. ( Fujimura, A; Ioka, T; Ookami, H; Sakamoto, K; Tsuruoka, S; Wakaumi, M, 2006) |
| "A 72-year-old woman with renal insufficiency who was taking oral pilsicainide (150 mg/d) complained of feeling faint 3 days after she was prescribed oral cetirizine (20 mg/d)." | 5.12 | Severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency: first case presentation showing competition for excretion via renal multidrug resistance protein 1 and organic cation transporter 2. ( Fujimura, A; Ioka, T; Ookami, H; Sakamoto, K; Tsuruoka, S; Wakaumi, M, 2006) |
| "Although the new second-generation nonsedative antihistamines terfenadine and astemizole were launched as highly selective and specific H(1)-receptor antagonists, they were later found to cause prolongation of the QT-interval and severe cardiac arrhythmias." | 4.81 | Cardiotoxicity of new antihistamines and cisapride. ( Paakkari, I, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L | 1 |
| Sun, H | 1 |
| Darpo, B | 1 |
| Benson, C | 1 |
| Brown, R | 1 |
| Dota, C | 1 |
| Ferber, G | 1 |
| Ferry, J | 1 |
| Jarugula, V | 1 |
| Keirns, J | 1 |
| Ortemann-Renon, C | 1 |
| Pham, T | 1 |
| Riley, S | 1 |
| Sarapa, N | 1 |
| Ticktin, M | 1 |
| Zareba, W | 1 |
| Couderc, JP | 1 |
| Tsuruoka, S | 1 |
| Ioka, T | 1 |
| Wakaumi, M | 1 |
| Sakamoto, K | 1 |
| Ookami, H | 1 |
| Fujimura, A | 1 |
| Whomsley, R | 1 |
| Strolin-Benedetti, M | 1 |
| Baltes, E | 1 |
| Clark, S | 1 |
| Coulie, P | 1 |
| Delaere, A | 1 |
| De Vos, C | 1 |
| Donnelly, F | 1 |
| Rihoux, JP | 1 |
| de Abajo, FJ | 1 |
| RodrÃguez, LA | 1 |
| Gilbert, JD | 1 |
| Cahill, SA | 1 |
| McCartney, DG | 1 |
| Lukas, A | 1 |
| Gross, GJ | 1 |
| Paakkari, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical ECG Study to Evaluate Electrophysiological Effects of Potential QT Prolonging Drugs With Novel ECG Biomarkers With Exposure-Response Analysis[NCT05716854] | Phase 1 | 44 participants (Actual) | Interventional | 2023-03-21 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for cetirizine and Arrhythmia
| Article | Year |
|---|---|
Cardiotoxicity of new antihistamines and cisapride.
Topics: Arrhythmias, Cardiac; Astemizole; Benzimidazoles; Butyrophenones; Cetirizine; Cisapride; Heart Disea | 2002 |
2 trials available for cetirizine and Arrhythmia
| Article | Year |
|---|---|
Evaluation of the Effect of 5 QT-Positive Drugs on the JTpeak Interval - An Analysis of ECGs From the IQ-CSRC Study.
Topics: Arrhythmias, Cardiac; Biomarkers; Cetirizine; Drug-Related Side Effects and Adverse Reactions; Elect | 2020 |
Severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency: first case presentation showing competition for excretion via renal multidrug resistance protein 1 and organic cation transporter 2.
Topics: Administration, Oral; Adult; Aged; Animals; Anti-Arrhythmia Agents; Area Under Curve; Arrhythmias, C | 2006 |
6 other studies available for cetirizine and Arrhythmia
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant | 2008 |
Comment on severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency.
Topics: Aged; Area Under Curve; Arrhythmias, Cardiac; Cetirizine; Drug Interactions; Female; Half-Life; Huma | 2006 |
Dangers of non-sedating antihistamines.
Topics: Arrhythmias, Cardiac; Astemizole; Cetirizine; Heart Diseases; Histamine H1 Antagonists; Humans; Legi | 1997 |
Non-sedating antihistamines and cardiac arrhythmias.
Topics: Arrhythmias, Cardiac; Cetirizine; Histamine H1 Antagonists; Humans; Risk Factors | 1998 |
Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Astemizole; Case-Control Studies; Cetirizine; Child; | 1999 |
Predictors of torsades de pointes in rabbit ventricles perfused with sedating and nonsedating histamine H1-receptor antagonists.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Astemizole; Cetirizine; Electrocardiography; Heart | 2000 |