Page last updated: 2024-10-24

cetirizine and Airway Hyper-Responsiveness

cetirizine has been researched along with Airway Hyper-Responsiveness in 10 studies

Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.

Research Excerpts

ExcerptRelevanceReference
"This study shows that cetirizine treatment reduces cough intensity (P < 0."6.68Cetirizine treatment of allergic cough in children with pollen allergy. ( Canonica, GW; Ciprandi, G; Fasce, L; Fregonese, L; Passalacqua, G; Ricca, V; Tosca, M, 1997)
"The pharmacokinetic/pharmacodynamic profile of levocetirizine was studied in 15 toddlers suffering from recurrent cough and other allergy-related symptoms, aged 20."5.11Levocetirizine in 1-2 year old children: pharmacokinetic and pharmacodynamic profile. ( Cranswick, N; Fuchs, M; Hulhoven, R; TurzĂ­kova, J, 2005)
"Sixteen atopic patients with mild-to-moderate asthma of whom 10 were receiving inhaled corticosteroid therapy (all had positive results to house dust mite on skin prick testing) were randomized in a double-blind, placebo-controlled, cross-over fashion to receive single doses of 5 mg of desloratadine, 180 mg of fexofenadine hydrochloride (FEX), 5 mg of levocetirizine dihydrochloride (LEV), or placebo, with AMP challenge performed 12 hours after dosing."5.10Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma. ( Bates, CE; Currie, GP; Lee, DK; Lipworth, BJ, 2003)
"Using human eosinophils isolated from patients with allergic rhinitis, the cells were cultured in vitro for 48 to 72 hours with medium, cetirizine, or dexamethasone in the presence of IL-5, IL-3, or GM-CSF."3.69Inhibitory effect of cetirizine on cytokine-enhanced in vitro eosinophil survival. ( Busse, WW; Sedgwick, JB, 1997)
"This study shows that cetirizine treatment reduces cough intensity (P < 0."2.68Cetirizine treatment of allergic cough in children with pollen allergy. ( Canonica, GW; Ciprandi, G; Fasce, L; Fregonese, L; Passalacqua, G; Ricca, V; Tosca, M, 1997)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's5 (50.00)18.2507
2000's4 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, DK1
Bates, CE1
Currie, GP1
Lipworth, BJ1
Magnan, A1
Cranswick, N1
TurzĂ­kova, J1
Fuchs, M1
Hulhoven, R1
Rihoux, JP1
Mariz, S1
Sedgwick, JB1
Busse, WW1
Ciprandi, G1
Tosca, M1
Ricca, V1
Passalacqua, G1
Fregonese, L1
Fasce, L1
Canonica, GW2
Bertrand, B1
Eloy, P1
Rombeaux, P1
Riemann, R1
Riemann, E1
Milewski, C1
Togias, AG1
Proud, D1
Kagey-Sobotka, A1
Freidhoff, L1
Lichtenstein, LM1
Naclerio, RM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Efficacy and Safety of Levocetirizine Dihydrochloride Oral Drops Given 0.125 mg/kg b.i.d. During 90 Days in the Treatment of Recurrent Cough Associated With Other Allergic Symptoms, e.g. Wheezing, in Children Aged 1-2 Years.[NCT00520754]Phase 215 participants (Actual)Interventional2001-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for cetirizine and Airway Hyper-Responsiveness

ArticleYear
Cetirizine. An updated review of its pharmacological properties and therapeutic efficacy.
    Clinical reviews in allergy, 1993,Spring, Volume: 11, Issue:1

    Topics: Animals; Cetirizine; Humans; Hypersensitivity, Immediate; Insect Bites and Stings; Respiratory Hyper

1993
Adhesion molecules and H1-antihistamines.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1997, Volume: 27 Suppl 2

    Topics: Cell Adhesion Molecules; Cetirizine; Histamine H1 Antagonists; Humans; Respiratory Hypersensitivity

1997
Allergy and sinusitis.
    Acta oto-rhino-laryngologica Belgica, 1997, Volume: 51, Issue:4

    Topics: Allergens; Anti-Allergic Agents; Anti-Inflammatory Agents; Beclomethasone; Blood Proteins; Cetirizin

1997

Trials

4 trials available for cetirizine and Airway Hyper-Responsiveness

ArticleYear
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
    The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:2

    Topics: Acetates; Adenosine Monophosphate; Adult; Aged; Asthma; Bronchial Provocation Tests; Cetirizine; Cro

2003
Levocetirizine in 1-2 year old children: pharmacokinetic and pharmacodynamic profile.
    International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:4

    Topics: Age Factors; Cetirizine; Cough; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Infant; Male

2005
Cetirizine treatment of allergic cough in children with pollen allergy.
    Allergy, 1997, Volume: 52, Issue:7

    Topics: Adolescent; Anti-Allergic Agents; Cetirizine; Child; Cough; Double-Blind Method; Female; Humans; Mal

1997
In vivo and in vitro effects of antihistamines on mast cell mediator release: a potentially important property in the treatment of allergic disease.
    Annals of allergy, 1989, Volume: 63, Issue:5

    Topics: Administration, Intranasal; Administration, Oral; Administration, Topical; Adolescent; Adult; Benzhy

1989

Other Studies

3 other studies available for cetirizine and Airway Hyper-Responsiveness

ArticleYear
[Respiratory allergies in the child and the adult].
    La Revue du praticien, 2004, Jan-31, Volume: 54, Issue:2

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Allergens; Anti-Allergic Ag

2004
Inhibitory effect of cetirizine on cytokine-enhanced in vitro eosinophil survival.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1997, Volume: 78, Issue:6

    Topics: Adult; Antibodies, Monoclonal; Cell Adhesion; Cell Survival; Cells, Cultured; Cetirizine; Chemotaxis

1997
[Skin prick test results in snoring and sleep apnea patients].
    Laryngo- rhino- otologie, 2002, Volume: 81, Issue:3

    Topics: Adolescent; Adult; Aged; Allergens; Cetirizine; Child; Female; Humans; Intradermal Tests; Male; Midd

2002