ceritinib and Neoplasms--Neuroepithelial

ceritinib has been researched along with Neoplasms--Neuroepithelial* in 2 studies

Other Studies

2 other study(ies) available for ceritinib and Neoplasms--Neuroepithelial

ArticleYear
Ceritinib-Induced Regression of an Insulin-Like Growth Factor-Driven Neuroepithelial Brain Tumor.
    International journal of molecular sciences, 2019, Aug-30, Volume: 20, Issue:17

    The insulin-like growth factor (IGF) pathway plays an important role in several brain tumor entities. However, the lack of inhibitors crossing the blood-brain barrier remains a significant obstacle for clinical translation. Here, we targeted the IGF pathway using ceritinib, an off-target inhibitor of the IGF1 receptor (IGF1R) and insulin receptor (INSR), in a pediatric patient with an unclassified brain tumor and a

    Topics: Adult; Arsenic Trioxide; Base Sequence; Brain; Brain Neoplasms; Cell Line, Tumor; Child, Preschool; Chromosome Aberrations; DNA Methylation; Female; Germ-Line Mutation; Humans; Insulin-Like Growth Factor I; Molecular Targeted Therapy; Neoplasms, Neuroepithelial; Principal Component Analysis; Pyrimidines; Receptor, Notch1; Sulfones; Transcriptome; Tumor Suppressor Protein p53

2019
IGF1R Is a Potential New Therapeutic Target for HGNET-BCOR Brain Tumor Patients.
    International journal of molecular sciences, 2019, Jun-21, Volume: 20, Issue:12

    (1)

    Topics: Antineoplastic Agents; Brain Neoplasms; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor II; Male; Molecular Targeted Therapy; Neoplasms, Neuroepithelial; Proto-Oncogene Proteins; Pyrimidines; Receptor, IGF Type 1; Receptors, Somatomedin; Repressor Proteins; Sulfones; Tumor Cells, Cultured; Vinblastine

2019