Page last updated: 2024-08-24

cephalosporin c and Leukemia

cephalosporin c has been researched along with Leukemia in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199019 (48.72)18.7374
1990's6 (15.38)18.2507
2000's9 (23.08)29.6817
2010's4 (10.26)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Artacho, A; Debrauwer, L; Djukovic, A; Garzón, MJ; González-Barberá, EM; Herrera, B; Kuster, B; López-Hontangas, JL; Peñaranda, I; Rolain, JM; Salavert, M; Sanz, J; Sanz, MA; Ubeda, C; Xavier, JB; Xavier, KB1
Barreto, JN; Dierkhising, RA; Gangat, N; Mara, KC; Tosh, PK; Yemm, KE1
Duffy, A; Gilmore, S; Heil, EL; Nguyen, AD; Patel, NK1
Aitken, SL; Bhatti, MM; DePombo, AM; Gettys, SC; Kontoyiannis, DP; Nicolau, DP; Nunez, CA; Tverdek, FP1
Bogue, CO; Daneman, A; Gerstle, JT; Moineddin, R; Murphy, AJ1
Gondoh, H; Hanada, S; Ikeda, S; Imamura, Y; Izumi, Y; Kawano, F; Masuda, M; Matsuishi, E; Matsuoka, H; Okamura, S; Saburi, Y; Shibuya, T; Tamura, K; Tsukada, J; Uike, N; Utsunomiya, A1
Fujii, N; Fukuda, S; Hara, M; Harada, M; Ikeda, K; Imajoh, K; Ishimaru, F; Kojima, K; Miyata, A; Nakase, K; Nawa, Y; Saito, T; Shinagawa, K; Sunami, K; Takeuchi, M; Tanimoto, M; Teshima, T; Yano, T1
Akiyama, N; Imajo, K; Masaoka, T; Ohyashiki, K; Suzuki, K; Tamura, K; Tanimoto, M; Urabe, A1
Benbachir, M; Benchekroun, S; Harif, M; Loukili, A; Mahmal, L; Quessar, A1
Bow, EJ; Laverdiere, M; Noskin, GA; Rotstein, C; Sanche, S; Schwarer, AP; Segal, BH; Seymour, JF; Szer, J1
Bodey, GP1
Komatsuda, M; Nagao, T; Nozaki, H; Yamauchi, K1
Chavanet, P; Cortet, P; Guy, H; Kazmierczak, A; Portier, H1
Galea, G1
Ishiyama, T; Miyayama, T; Nomoto, H; Shiokawa, Y; Sugaya, N; Sugimoto, M; Wakabayashi, Y1
Arimori, S; Komatsuda, M; Nagao, T; Nozaki, H; Yamauchi, K1
Hasegawa, S; Nakao, I1
Hasegawa, H; Horiuchi, A; Kanamaru, A; Kawagoe, H; Kitani, T; Masaoka, T; Matsubuchi, T; Nagai, K; Shibata, H; Shinohara, Y; Tsubakio, T; Yonezawa, T1
Bhaduri, S; Heimpel, H; Krieger, D; Kurrle, E; Pflieger, H1
Miser, AW; Miser, JS1
Charnas, R; Lüthi, AR; Ruch, W1
Jabbar, A; Siddique, T1
Filatov, LB; Iarikova, EN; Isaev, VG; Kaletin, GI; Kaporskaia, TS; Kliasova, GA; Klimko, NN; Lapin, VA; Medvedeva, NV; Parovichnikova, EN; Porokhona, ON; Pristupa, AS; Rekhtman, GB; Rossiev, VA; Savchenko, VG; Sharov, LN; Tolkacheva, TV; Tumakov, VA1
Horiike, S; Iwai, T; Kaneko, H; Kashima, K; Misawa, S; Nakazawa, N; Ohgawara, Y; Sasai, Y; Tamura, A; Taniwaki, M; Tsuda, S; Ueda, Y; Yokota, S1
Egerer, G; Fenchel, K; Franke, A; Heil, G; Jürgens, H; Kämpfe, D; Karthaus, M; Peters, G; Ritter, J; Südhoff, T1
Heiss, M; Kern, WV; Steinbach, G1
Ljungberg, B; Nilsson-Ehle, I; Nyhlén, A1
Akan, H; Akova, M; Cetinkaya, Y; Erman, M; Ferhanoğlu, B; Köksal, I; Korten, V; Unal, S; Uzun, O1
Lantz, B; Reizenstein, P1
Imai, K; Kamiya, T; Koie, K; Ono, R; Yoshikawa, H1
Akasaka, K; Furukawa, Y; Im, T; Inoue, K; Kageyama, T; Nasu, K; Ohyabu, H; Sannomiya, Y; Tatsumi, N; Yonezawa, T1
Horiike, S; Misawa, S; Nakagawa, H; Nishigaki, H; Okuda, T; Takino, T; Tanaka, S; Taniwaki, M; Tsuda, S; Yashige, H1
de Pauw, BE; Haanen, C; Stalpers, LJ; Verhagen, C1
Atogami, S; Itoyama, T; Kamihira, S; Kohno, T; Maeda, T; Moriuchi, Y; Sasagawa, I; Tomonaga, M; Tsukasaki, K; Yamaguchi, K1
Funada, H; Machi, T; Matsuda, T1
Moellering, RC1
Bernadou, A; Bilski-Pasquier, G; Bousser, J; Dao, C; Gerbal, R; Zittoun, R1
Bieder, L; Little, PJ1

Trials

14 trial(s) available for cephalosporin c and Leukemia

ArticleYear
Cefepime or carbapenem treatment for febrile neutropenia as a single agent is as effective as a combination of 4th-generation cephalosporin + aminoglycosides: comparative study.
    American journal of hematology, 2002, Volume: 71, Issue:4

    Topics: Adult; Algorithms; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Humans; Leukemia; Lymphoma; Male; Neutropenia

2002
[Clinical evaluation of cefozopran as treatment for febrile neutropenia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Bacterial Agents; Cefozopran; Cephalosporins; Female; Fever; Humans; Leukemia; Male; Middle Aged; Neutropenia

2004
Randomized trial of cefepime monotherapy or cefepime in combination with amikacin as empirical therapy for febrile neutropenia.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Jul-15, Volume: 39 Suppl 1

    Topics: Amikacin; Antineoplastic Agents; Bacteremia; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Hematologic Diseases; Humans; Immunocompromised Host; Japan; Leukemia; Male; Neutropenia; Opportunistic Infections

2004
A randomized, open-label, multicenter comparative study of the efficacy and safety of piperacillin-tazobactam and cefepime for the empirical treatment of febrile neutropenic episodes in patients with hematologic malignancies.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Aug-15, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Fever; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Treatment Outcome

2006
Antimicrobial prophylaxis in acute leukaemia: prospective randomized study comparing two methods of selective decontamination.
    Klinische Wochenschrift, 1983, Jul-15, Volume: 61, Issue:14

    Topics: Acute Disease; Adolescent; Adult; Aged; Aminoglycosides; Amphotericin B; Anti-Bacterial Agents; Bacterial Infections; Candidiasis; Cephalosporins; Enterobacteriaceae Infections; Female; Flucytosine; Humans; Leukemia; Male; Middle Aged; Oxacillin; Penicillins; Prospective Studies; Staphylococcal Infections; Streptococcal Infections

1983
Equivalent efficacies of meropenem and ceftazidime as empirical monotherapy of febrile neutropenic patients. The Meropenem Study Group of Leuven, London and Nijmegen.
    The Journal of antimicrobial chemotherapy, 1995, Volume: 36, Issue:1

    Topics: Adolescent; Adult; Aged; Bacterial Infections; Ceftazidime; Cephalosporins; Female; Fever; Humans; Leukemia; Leukocyte Count; Male; Meropenem; Middle Aged; Neutropenia; Prospective Studies; Thienamycins; Treatment Failure

1995
Once daily ceftriaxone plus amikacin vs. three times daily ceftazidime plus amikacin for treatment of febrile neutropenic children with cancer. Writing Committee for the International Collaboration on Antimicrobial Treatment of Febrile Neutropenia in Chil
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:4

    Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Child; Child, Preschool; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Fever; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Infant; Leukemia; Lymphoma; Male; Microbial Sensitivity Tests; Neoplasms; Neutropenia

1997
[The empirical antibiotic therapy of patients with acute leukemias: the results of a multicenter study].
    Terapevticheskii arkhiv, 1998, Volume: 70, Issue:7

    Topics: Acute Disease; Adult; Ampicillin; Anti-Bacterial Agents; Cefoperazone; Cephalosporins; Drug Therapy, Combination; Fever of Unknown Origin; Fluconazole; Gentamicins; Humans; Leukemia; Russia; Sulbactam; Time Factors; Ukraine

1998
[Clinical evaluation of cefozopran for infections associated with hematological malignancies].
    The Japanese journal of antibiotics, 1998, Volume: 51, Issue:8

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Bacterial Infections; Bronchitis; Cefozopran; Cephalosporins; Female; Granulocytes; Hodgkin Disease; Humans; Leukemia; Leukemia, Myeloid, Acute; Leukemia, T-Cell; Leukocyte Count; Lymphoma; Male; Middle Aged; Multiple Myeloma; Peritonitis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sepsis; Severity of Illness Index

1998
Interventional once-daily administration of ceftriaxone in leukemia and lymphoma patients with febrile neutropenia.
    Antibiotics and chemotherapy, 2000, Volume: 50

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bacterial Infections; Ceftriaxone; Cephalosporins; Female; Humans; Leukemia; Lymphoma; Male; Middle Aged; Neutropenia; Treatment Outcome

2000
Comparison of cefepime and ceftazidime in combination with amikacin in the empirical treatment of high-risk patients with febrile neutropenia: a prospective, randomized, multicenter study.
    Scandinavian journal of infectious diseases, 2001, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Amikacin; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Drug Therapy, Combination; Fever; Humans; Leukemia; Lymphoma, Non-Hodgkin; Neutropenia; Prospective Studies; Risk Factors; Treatment Outcome

2001
Management of septicemia and early death in acute leukemia.
    Acta medica Scandinavica, 1977, Volume: 202, Issue:6

    Topics: Acute Disease; Blood Transfusion; Cephalosporins; Female; Granulocytes; Humans; Intestines; Leukemia; Leukocyte Count; Male; Patient Isolation; Penicillins; Remission, Spontaneous; Sepsis; Streptomycin

1977
[Therapeutic effects of cefclidin against severe infections in patients with hematopoietic disorders. Hanshin Infection Study Group].
    The Japanese journal of antibiotics, 1992, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cephalosporins; Child; Female; Humans; Immunocompromised Host; Leukemia; Leukocyte Count; Lymphoma; Male; Middle Aged; Neutrophils; Respiratory Tract Infections; Sepsis

1992
Can the third-generation cephalosporins eliminate the need for antimicrobial combinations?
    The American journal of medicine, 1985, Aug-09, Volume: 79, Issue:2A

    Topics: Abdomen; Bacterial Infections; Cephalosporins; Clinical Trials as Topic; Drug Therapy, Combination; Endometritis; Female; Humans; Leukemia; Neoplasms

1985

Other Studies

25 other study(ies) available for cephalosporin c and Leukemia

ArticleYear
High Heterogeneity of Multidrug-Resistant
    Antimicrobial agents and chemotherapy, 2020, 01-27, Volume: 64, Issue:2

    Topics: Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Culture Media; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Feces; Hospitalization; Humans; Injections, Intravenous; Leukemia; Microbial Sensitivity Tests; Prospective Studies

2020
A comparison of levofloxacin and oral third-generation cephalosporins as antibacterial prophylaxis in acute leukaemia patients during chemotherapy-induced neutropenia.
    The Journal of antimicrobial chemotherapy, 2018, Jan-01, Volume: 73, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Bacteremia; Cephalosporins; Febrile Neutropenia; Female; Hematologic Neoplasms; Humans; Leukemia; Levofloxacin; Male; Middle Aged; Retrospective Studies; Young Adult

2018
A single-center evaluation of the risk for colonization or bacteremia with piperacillin-tazobactam- and cefepime-resistant bacteria in patients with acute leukemia receiving fluoroquinolone prophylaxis.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2016, Volume: 22, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Leukemia; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Post-Exposure Prophylaxis; Random Allocation; Retrospective Studies; Risk Factors; Young Adult

2016
Use of Ceftolozane/Tazobactam in the Treatment of Multidrug-resistant Pseudomonas aeruginosa Bloodstream Infection in a Pediatric Leukemia Patient.
    The Pediatric infectious disease journal, 2016, Volume: 35, Issue:9

    Topics: Anti-Bacterial Agents; Bacteremia; Cephalosporins; Child; Drug Resistance, Multiple, Bacterial; Hospitalization; Humans; Leukemia; Male; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam

2016
Risk factors, complications, and outcomes of gallstones in children: a single-center review.
    Journal of pediatric gastroenterology and nutrition, 2010, Volume: 50, Issue:3

    Topics: Adolescent; Age Distribution; Anemia, Hemolytic; Cephalosporins; Chi-Square Distribution; Child; Child, Preschool; Cholecystectomy; Cholelithiasis; Female; Gallstones; Heart Diseases; Humans; Infant; Leukemia; Lymphoma; Male; Parenteral Nutrition; Prognosis; Retrospective Studies; Risk Factors; Short Bowel Syndrome; Treatment Outcome

2010
[Germs that produce the extended spectrum betalactamases].
    La Tunisie medicale, 2004, Volume: 82, Issue:11

    Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Cross Infection; Emergencies; Escherichia coli; Escherichia coli Infections; Female; Hospitals, University; Humans; Imipenem; Leukemia; Lymphoma, Non-Hodgkin; Male; Morocco; Neutropenia; Retrospective Studies; Shock, Septic; Time Factors

2004
Candidiasis in cancer patients.
    The American journal of medicine, 1984, Oct-30, Volume: 77, Issue:4D

    Topics: Amphotericin B; Antibodies, Fungal; Candidiasis; Cephalosporins; Humans; Ketoconazole; Leukemia; Miconazole; Neoplasms; Pneumonia

1984
Clinical evaluation of combination of cefmetazole and piperacillin in the treatment of infections in patients with acute leukemia.
    Chemotherapy, 1983, Volume: 29, Issue:3

    Topics: Acute Disease; Adult; Aged; Bacterial Infections; Cefmetazole; Cephalosporins; Cephamycins; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Penicillins; Piperacillin

1983
[Combined cefotaxime-amikacin treatment of infectious episodes in acute leukaemia patients with therapeutically-induced bone marrow aplasia (author's transl)].
    La Nouvelle presse medicale, 1981, Feb-26, Volume: 10, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Cefotaxime; Cephalosporins; Drug Therapy, Combination; Humans; Kanamycin; Leukemia; Middle Aged

1981
Management of bacterial infections in haematological patients.
    British journal of hospital medicine, 1982, Volume: 28, Issue:1

    Topics: Acute Disease; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Drug Combinations; Hematologic Diseases; Humans; Immunosuppression Therapy; Leukemia; Leukemia, Lymphoid; Lymphoma; Multiple Myeloma; Neutropenia; Penicillins; Polymyxins

1982
[Clinical investigation of combined therapy (cefotiam, sulbenicillin and cefsulodin) against infections complicated by acute leukemia].
    The Japanese journal of antibiotics, 1983, Volume: 36, Issue:1

    Topics: Acute Disease; Adult; Bacterial Infections; Cefotaxime; Cefotiam; Cefsulodin; Cephalosporins; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Penicillin G; Sulbenicillin

1983
Evaluation of cefmetazole and piperacillin with or without tobramycin for infections in patients with hematological disorders.
    The Tokai journal of experimental and clinical medicine, 1981, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Anti-Bacterial Agents; Bacterial Infections; Cefmetazole; Cephalosporins; Cephamycins; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Leukemia; Leukocyte Count; Lymphoma; Male; Middle Aged; Neutrophils; Penicillins; Piperacillin; Tobramycin

1981
[Experience in combination therapy with amikacin and cephapirin for infections complicated with acute leukemia during induction chemotherapy].
    The Japanese journal of antibiotics, 1984, Volume: 37, Issue:9

    Topics: Acute Disease; Adult; Amikacin; Antineoplastic Agents; Bacterial Infections; Cephalosporins; Cephapirin; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Kanamycin; Leukemia; Male; Middle Aged

1984
[Cooperative studies on clinical effect of cefotetan for severe infections combined with hematologic disorders].
    The Japanese journal of antibiotics, 1983, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Bacterial Infections; Cefotetan; Cephalosporins; Cephamycins; Child; Female; Hematologic Diseases; Humans; Infusions, Parenteral; Leukemia; Lymphoma; Male; Middle Aged

1983
Staphylococcus aureus sepsis in childhood malignancy.
    American journal of diseases of children (1960), 1980, Volume: 134, Issue:9

    Topics: Cephalosporins; Child; Female; Humans; Leukemia; Lymphoma; Male; Neoplasms; Penicillins; Staphylococcal Infections

1980
A case of pseudolymphoma leukaemia syndrome following cefixime.
    British journal of haematology, 1998, Volume: 101, Issue:1

    Topics: Cefixime; Cefotaxime; Cephalosporins; Diagnosis, Differential; Female; Humans; Leukemia; Middle Aged; Pseudolymphoma; Sezary Syndrome

1998
Prediction of gram-negative bacteremia in patients with cancer and febrile neutropenia by means of interleukin-8 levels in serum: targeting empirical monotherapy versus combination therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Mar-01, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteremia; Cefepime; Cephalosporins; Drug Therapy, Combination; Fever; Gentamicins; Gram-Negative Bacterial Infections; Humans; Interleukin-8; Leukemia; Lymphoma; Male; Middle Aged; Netilmicin; Neutropenia; Predictive Value of Tests; Prospective Studies

2001
Pharmacokinetics of ceftazidime in febrile neutropenic patients.
    Scandinavian journal of infectious diseases, 2001, Volume: 33, Issue:3

    Topics: Adult; Aged; Area Under Curve; Ceftazidime; Cephalosporins; Female; Fever; Glomerular Filtration Rate; Half-Life; Humans; Injections, Intravenous; Leukemia; Male; Microbial Sensitivity Tests; Middle Aged; Neutropenia

2001
[The bacterial infections in patients with acute leukemia and their treatment by antibiotics, with special reference to Klebsiella and Pseudomonas infections (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1975, Volume: 16, Issue:7

    Topics: Acute Disease; Adult; Anti-Bacterial Agents; Cephalosporins; Humans; Klebsiella Infections; Leukemia; Male; Penicillins; Pseudomonas Infections

1975
[Clinical evaluation of cefpiramide for infections in leukemia and related disorders].
    The Japanese journal of antibiotics, 1989, Volume: 42, Issue:8

    Topics: Adolescent; Adult; Aged; Bacterial Infections; Cephalosporins; Female; Humans; Leukemia; Male; Middle Aged

1989
Drug-induced skin reactions in patients with acute non-lymphocytic leukaemia.
    European journal of haematology, 1987, Volume: 38, Issue:3

    Topics: Acute Disease; Adult; Allopurinol; Cephalosporins; Drug Combinations; Drug Eruptions; Female; Humans; Ketoconazole; Leukemia; Male; Miconazole; Penicillins; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1987
[Combined antibiotic therapy of infections in patients with acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:9

    Topics: Acute Disease; Adult; Aminoglycosides; Anti-Bacterial Agents; Cephalosporins; Drug Therapy, Combination; Fever of Unknown Origin; Humans; Infections; Leukemia; Middle Aged; Piperacillin; Ticarcillin

1988
Bacteremia complicating acute leukemia with special reference to its incidence and changing etiological patterns.
    Japanese journal of clinical oncology, 1988, Volume: 18, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Bacteria; Cephalosporins; Child; Cross Infection; Female; Humans; Leukemia; Male; Middle Aged; Sepsis; Serotyping

1988
[Prevention of infectious complications of acute leukemias: place of general and intestinal antibiotic therapy].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1973, Mar-26, Volume: 49, Issue:15

    Topics: Administration, Oral; Ampicillin; Anti-Bacterial Agents; Cephalosporins; Cross Infection; Humans; Infection Control; Infections; Leukemia; Nystatin; Sepsis

1973
Cephalexin: a new cephalosporin derivative.
    The Medical journal of Australia, 1970, Jun-06, Volume: 1, Issue:23

    Topics: Administration, Oral; Bronchiectasis; Carcinoma; Cephalosporins; Diabetes Complications; Humans; Infections; Kidney Calculi; Leukemia; Lung Neoplasms; Respiratory Tract Infections; Urinary Tract Infections; Urination Disorders; Urine

1970