cephalosporin c has been researched along with Disease Models, Animal in 185 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (16.76) | 18.7374 |
| 1990's | 44 (23.78) | 18.2507 |
| 2000's | 56 (30.27) | 29.6817 |
| 2010's | 49 (26.49) | 24.3611 |
| 2020's | 5 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Cumper, C; Jones, M; Litherland, K; Richards, C; Smart, J | 1 |
| Chun, J; Miura, NN; Miyabe, C; Miyabe, Y; Miyasaka, M; Miyasaka, N; Nagai, J; Nanki, T; Ohno, N; Tsuboi, R; Ueda, H | 1 |
| Abdelraouf, K; Kidd, JM; Nicolau, DP | 1 |
| Arias, CA; Dinh, AQ; Kebriaei, R; Khan, A; Murray, BE; Rice, SA; Rybak, MJ; Singh, KV; Stamper, KC; Tran, TT | 1 |
| Canovas, J; Chau, F; Fantin, B; Le Monnier, A; Lefort, A; Petitjean, G | 1 |
| Huang, Q; Liu, J; Song, J; Wei, F; Yang, L; Zhang, Z; Zhou, G | 1 |
| Ashbaugh, AG; Jain, SK; Miller, LS; Miller, RJ; Ordonez, AA; Ortines, RV; Saini, V; Sterling, RS; Thompson, JM; Wang, Y | 1 |
| Çelenk, FG; Coşkunsever, D; Nalbant, S; Önal, A; Şentürk, RS; Ülker Göksel, S | 1 |
| Echols, R; Hoover, J; Matsumoto, S; Nakamura, R; Rittenhouse, S; Singley, CM; Tsuji, M; Yamano, Y | 1 |
| Cho, YL; Kim, HS; Kwak, JH; Oh, K; Oh, SH; Park, HS; Yun, JY | 1 |
| Monogue, ML; Nicolau, DP | 2 |
| Ghazi, IM; Monogue, ML; Nicolau, DP; Tsuji, M | 1 |
| Dai, C; Hao, Z; Li, Y; Qu, S; Zhao, L; Zhu, J | 1 |
| Deng, Z; Li, G; Li, X; Liang, W; Liu, J; Ou, HY; Qu, H; Sun, J; Tian, L; Wang, X; Xie, Y | 1 |
| Huo, X; Liu, K; Liu, Z; Ma, X; Meng, Q; Peng, J; Sun, H; Sun, P; Wang, C; Wang, H | 1 |
| Ambati, A; Babar, MM; Inayathullah, M; Kim, KM; Maguire, P; Parekh, MB; Pothineni, VR; Potula, HS; Rajadas, J; Tayebi, L | 1 |
| Cha, SS; Chung, KM; Jeong, BG; Kim, MK; Lee, TH; Na, JH; Park, SB | 1 |
| Dai, C; Hao, Z; Huang, T; Qu, S; Tang, Q; Wang, H; Yang, F; Zhang, Y | 1 |
| Acosta, F; Cottagnoud, M; Cottagnoud, P; Stucki, A | 1 |
| Artzi, N; Barnea, Y; Carmeli, Y; Kuzmenko, B; Navon-Venezia, S | 1 |
| Akpolat, N; Aydemir, O; Deniz, N; Güler, M; Kizirgil, A | 1 |
| Ding, H; Liang, C; Shan, Q; Wang, J; Zeng, Z | 1 |
| Almirante, B; Miró, JM; Pericás, JM | 1 |
| Cantin, M; Constandil, L; Herrera, N; Rodas, PI; Velasquez, LA; Vilos, C; Zepeda, K | 1 |
| Cheung, AW; Cho, EY; Sha, O; Wong, WK; Yu, SW | 1 |
| Boutoille, D; Bretonnière, C; Caillon, J; Desessard, C; Guitton, C; Jacqueline, C; Potel, G | 1 |
| Crémieux, AC; Gatin, L; Ghout, I; Laurent, F; Saleh-Mghir, A; Tasse, J | 1 |
| Bhalodi, AA; Crandon, JL; Nicolau, DP; Williams, G | 1 |
| Cao, Y; Ding, Z; Gong, Y; Jiang, H; Liu, X; Song, X; Wang, F; Wang, T; Wang, W; Zhang, N; Zhang, W; Zhang, Z | 1 |
| Bonnet, R; Dalmasso, G; Delmas, J; Gibold, L; Robin, F; Serres, A | 1 |
| Ding, H; Gu, M; Gu, X; Li, X; Li, Y; Shen, X; Zhang, B; Zhang, N | 1 |
| Dvornik, IA; Nepomnyashchiy, VV; Shakalova, EA; Tamm, TI | 1 |
| Ariza, J; Cabellos, C; El Haj, C; Force, E; Tubau, F; Vivas, M | 1 |
| Guo, C; Liao, X; Liu, Y; Sun, J; Wang, F; Wang, M; Xiao, X; Yan, C | 1 |
| Hammer, E; Hildebrandt, O; Lindequist, U; Mikolasch, A; Schlüter, R; Witt, S | 1 |
| Davis, JL; Dixon, LW; Fales, WH; Giguère, S; Hooper, SE; Korte, SW | 1 |
| Chen, MR; Li, X; Liao, XP; Liu, YH; Qiao, GL; Sun, J; Yu, Y; Zhou, YF | 1 |
| Becker, KJ; Fecteau, L; Kunze, A; Lee, B; Skerrett, S; Zierath, D | 1 |
| Hori, T; Ishikura, K; Nakamura, R; Tsuji, M; Yamano, Y; Yamawaki, K; Yokoo, K; Yonezawa, S; Yoshida, Y | 1 |
| Galvão, KN; Jeon, SJ; Jeong, KC; Kang, M; Ma, Z | 1 |
| Domínguez-Herrera, J; Labrador-Herrera, G; López-Rojas, R; Pachón, J; Smani, Y | 1 |
| Andes, DR; Craig, WA | 1 |
| An, N; Ci, X; Deng, X; Li, H; Song, Y; Yu, Q; Zeng, F | 1 |
| Abbas, M; Elsebae, M; Farouk, Y; Nafeh, AE | 1 |
| Rybak, MJ; Vidaillac, C | 1 |
| Drusano, GL; Gotfried, M; Kahn, JB; Khashab, M; Laohavaleeson, S; Lodise, TP; Murray, SA; Nicholson, S; Nicolau, DP; Noel, GJ; Rodvold, KA; Tessier, PR | 1 |
| Ganea, GM; Goetz, RM; Stein, RA | 1 |
| Basuino, L; Bauer, D; Chambers, HF; Diep, BA; Tattevin, P | 1 |
| Hou, J; Ledesma, KR; Prince, RA; Singh, R; Tam, VH; Yuan, Z | 1 |
| Amador, G; Batard, E; Biek, D; Caillon, J; Ge, Y; Hamel, A; Jacqueline, C; Le Mabecque, V; Miègeville, AF; Potel, G | 1 |
| Aguilar, L; Alou, L; Cafini, F; Coronel, P; García, E; Giménez, MJ; González, N; Prieto, J; Ramos-Sevillano, E; Sevillano, D; Torrico, M; Yuste, J | 1 |
| Amador, G; Batard, E; Biek, D; Caillon, J; Ge, Y; Jacqueline, C; Le Mabecque, V; Potel, G | 1 |
| Amador, G; Batard, E; Biek, D; Caillon, J; Jacqueline, C; Le Mabecque, V; Miègeville, AF; Potel, G | 1 |
| Tuğrul, HM; Yıldırım, MI | 1 |
| Bulik, CC; Keel, RA; Nicolau, DP; Sutherland, CA; Tessier, PR | 1 |
| Acosta, F; Cottagnoud, M; Cottagnoud, P; Egerman, U; Läuffer, J; Stucki, A | 1 |
| Acosta, F; Cottagnoud, M; Cottagnoud, P; Egerman, U; Laeuffer, JM; Stucki, A | 1 |
| Breyne, K; Demon, D; Dörner, JC; Froyman, R; Guédé, D; Ludwig, C; Meyer, E | 1 |
| Amador, G; Asehnoune, K; Boutoille, D; Broquet, A; Caillon, J; Desessard, C; Jacqueline, C; Le Mabecque, V; Potel, G; Roquilly, A | 1 |
| Azeh, I; Eiffert, H; Gerber, J; Koenig, B; Nau, R; Wellhausen, M; Wellmer, A | 1 |
| Echchannaoui, H; Frei, K; Landmann, R; Leib, SL; Schnell, C; Zimmerli, W | 1 |
| Bronson, JJ; Goodrich, J; Luh, BY; Springer, DM | 1 |
| Bronson, JJ; Goodrich, JT; Luh, BY; Springer, DM | 1 |
| Bowden, B; Hirst, R; Norton, R; Powell, K; Ulett, GC | 1 |
| Antzaklis, G; Douridas, G; Giamarellos-Bourboulis, EJ; Giamarellou, H; Kanara, M; Karayannacos, P; Papagoras, D; Paraskevopoulos, I | 1 |
| Hiyama, E; Kodama, T; Sueda, T; Tsumura, H; Yokoyama, T | 1 |
| Cartier, LL; Cheung, BW; Giebink, GS; Sawchuk, RJ; Zhu, T | 1 |
| Hashiguchi, S; Iizawa, Y; Ishikawa, T; Miyake, A; Nagai, J; Nakao, M; Okonogi, K | 1 |
| Anglade, D; Bayat, S; Fraisse, F; Grimbert, FA; Louchahi, K; Petitjean, O; Rahoui, A; Sorin, PM; Tod, M; Verdière, B | 1 |
| Bugnon, D; Caillon, J; Gras-Le Guen, C; Jacqueline, C; Kergueris, MF; Navas, D; Potel, G | 1 |
| Nikitenko, VI | 1 |
| Chambers, HF | 2 |
| Conejo, C; Ibáñez-Martínez, J; Martínez-Martínez, L; Pachón, J; Pachón-Ibañez, ME; Pascual, A; Pichardo, C; Rodríguez-Martínez, JM | 1 |
| Cartier, LL; Cheung, BW; Ji, P; Sawchuk, RJ | 1 |
| Ascioti, C; De Sarro, A; De Sarro, G; Nisticó, G | 1 |
| Beghi, E; Bendotti, C; Mennini, T | 1 |
| Corcoran, E; Dudley, MN; Griffith, DC; Rodriguez, D | 1 |
| Calhoun, JH; Schmitt-Hoffmann, A; Shapiro, S; Thomas, JK; Yin, LY | 1 |
| Cabellos, C; Domenech, A; Force, E; Gudiol, F; Ribes, S; Taberner, F; Tubau, F; Viladrich, PF | 1 |
| Laohavaleeson, S; Nicolau, DP; Tessier, PR | 1 |
| Fitzgerald, RH | 1 |
| Beam, TR | 1 |
| Loock, CA; McCracken, GH; Schaad, UB; Thomas, ML | 1 |
| Dreznik, Z; Mark, Z; Rubinstein, E | 1 |
| Actor, P; Grappel, SF; Lewis, HB; Morgan, DG; Phillips, L | 1 |
| Imori, T; Kamata, Y; Matsuda, H; Tohjo, M | 1 |
| Goldman, PL; Petersdorf, RG | 1 |
| Ebright, JR; Fekety, R; Silva, J; Wilson, KH | 1 |
| Zak, O | 1 |
| Nishi, T; Tsuchiya, K | 1 |
| Brandt, CM; Rouse, MS; Steckelberg, JM; Tallan, BM; Wilson, WR | 1 |
| Munakata, K; Satoh, M; Takeuchi, H; Yoshida, O | 2 |
| Ehrett, S; Friedland, IR; Hickey, S; McCracken, GH; Olsen, K; Paris, M | 1 |
| Brook, I; Gilmore, JD | 1 |
| Barza, M; Baum, JL; Lynch, E | 1 |
| Ehrett, S; Friedland, IR; Krisher, K; McCracken, GH; Paris, M; Rinderknecht, S; Shelton, S | 1 |
| Aguilar, HE; Drews, C; Gardner, S; Grossniklaus, H; Meredith, TA; Sawant, AD | 1 |
| Dalhoff, A; Nitsche, D; Oesser, S; Sack, M; Schulze, C | 1 |
| Furuya, N; Hirakata, Y; Matsumoto, T; Tateda, K; Yamaguchi, K | 1 |
| Cavalier, A; Elkhaïli, H; Jehl, F; Kaltenbach, G; Levêque, D; Monteil, H; Peter, JD; Salmon, J; Salmon, Y | 1 |
| Nieto, E; Parra, A; Ponte, C; Soriano, F | 2 |
| Gemba, M; Kawai, Y | 1 |
| Aguilar, HE; Drews, C; Gardner, S; Grossniklaus, HE; Meredith, TA; Sawant, A; Wilson, LA | 1 |
| Azoulay-Dupuis, E; Bédos, JP; Carbon, C; Darras-Joly, C; Moine, P; Rieux, V; Sauve, C | 1 |
| Alfaro, DV; Barton, CP; Beverly, DT; Brucker, AJ; Hudson, SJ; Kasowski, EJ; King, LP; Lopez, JD | 1 |
| Brück, W; Fischer, FR; Nau, R; Schmidt, H; Stringaris, AK; Stuertz, K; Zysk, G | 1 |
| Elkhaïli, H; Jehl, F; Levêque, D; Linger, L; Monteil, H; Niedergang, S; Peter, JD; Pompei, D; Salmon, J; Salmon, Y; Thierry, RC | 1 |
| Bryant, AE; Stevens, DL | 1 |
| D'Amico, DT; Ng, EW | 1 |
| Battles, A; Liu, QF; Liu, W; Louie, A; Miller, DA; Miller, MH; Sucke, AC | 1 |
| Kajiyama, G; Schurman, DJ; Smith, RL | 1 |
| Ahlgren, B; Bernhard, M; Guiboux, JP; Herkowitz, HN; Patti, JE; Zervos, M | 1 |
| Jacolot, A; Mimoz, O; Padoin, C; Petitjean, O; Samii, K; Tod, M | 1 |
| Ponte, C; Soriano, F | 1 |
| Bornitz, F; Hof, H; Kretschmar, M; Nichterlein, T | 1 |
| Ryzhko, IV; Samokhodkina, ED; Shcherbaniuk, AI; Tsetskhladze, NS; Tsuraeva, RI | 1 |
| Harada, N; Irie, T; Isobe, H; Liu, W; Murakami, K; Okajima, K | 1 |
| Friedland, IR; Ghaffar, F; Jafri, H; Lutsar, I; McCracken, GH; Ng, W; Wubbel, L | 1 |
| Aguilar, L; Cenjor, C; García-Calvo, G; Giménez, MJ; Nieto, E; Parra, A; Ponte, C; Soriano, F | 2 |
| Elhelali, N; Jacolot, A; Laurent, F; Léotard, S; Mimoz, O; Nordmann, P; Petitjean, O; Samii, K | 1 |
| Hirst, RG; Norton, RE; Ulett, GC | 1 |
| Eiffert, H; Mäder, M; Nau, R; Schmidt, H; Stuertz, K; Trostdorf, F | 1 |
| Banevicius, MA; Bui, KQ; Nicolau, DP; Nightingale, CH; Quintiliani, R | 1 |
| Gerber, J; Henne, S; Maier, K; Nau, R; Smirnov, A; Wellmer, A | 1 |
| Cottagnoud, M; Cottagnoud, P; Gerber, CM; Neftel, KA; Täuber, MG | 1 |
| Banevicius, MA; Nicolau, DP; Nightingale, CH; Onyeji, CO; Tessier, PR; Zhong, M | 1 |
| de Sá Del Fiol, F; Groppo, FC; Rocha De Mattos Filho, T | 1 |
| Entenza, JM; Féger, C; Glauser, MP; Moreillon, P; Vouillamoz, J | 1 |
| Acosta, F; Cottagnoud, M; Cottagnoud, P; Neftel, K; Täuber, MG | 1 |
| Baquero, F; Blázquez, J; Levin, BR; Lipsitch, M; Negri, MC | 1 |
| Akiyama, M; Matsumoto, K; Oishi, K; Pollack, M; Tao, M | 1 |
| Kim, MY; Lee, CS; Paek, KS; Youn, H | 1 |
| Felts, AG; Grainger, DW; Slunt, JB | 1 |
| Angehrn, P; Hebeisen, P; Heinze-Krauss, I; Hohl, P; Page, MG; Then, RL | 1 |
| Cacciapuoti, A; Nowakowski, J; Pavia, CS; Wormser, GP | 1 |
| Bhattacharjee, AK; Cross, AS; Glaser, K; Opal, SM; Palardy, JE; Parejo, NA; Warren, HS | 1 |
| Baron, D; Bugnon, D; Caillon, J; Dube, L; Kergueris, MF; Le Conte, P; Navas, D; Potel, G; Robaux, MA | 1 |
| Acosta, F; Cottagnoud, M; Cottagnoud, P; Gerber, CM; Perrig, M; Täuber, MG | 1 |
| Aguilar, L; Alkorta, M; Giménez, MJ; Pérez-Trallero, E; Vicente, D | 1 |
| Brück, W; Gerber, J; Kunst, T; Nau, R; Noeske, C; Raivich, G; Wellmer, A; Werner, A | 1 |
| Ikeda, F; Ikemoto, A; Matsumoto, K; Matsumoto, Y; Tawara, S; Wakai, Y | 1 |
| Morrison, DC; Opal, SM; Palardy, JE; Parejo, N | 1 |
| Abe, T; Fukuoka, T; Inoue, H; Ohya, S | 1 |
| Amorena, B; García-Alvarez, F; Gracia, E; Laclériga, A; Leiva, J; Monzón, M; Oteiza, C | 1 |
| Inchiosa, MA; Pavia, C; Wormser, GP | 1 |
| Ahmed, K; Al-Sweih, NN; Anim, JT; Khodakhast, FB; Rotimi, VO; Verghese, TL | 1 |
| Higashiyama, Y; Hirakata, Y; Kadota, JI; Kakeya, H; Kaneko, Y; Kohno, S; Kuroki, M; Miyazaki, Y; Ohi, H; Tomono, K; Yanagihara, K | 1 |
| Almirante, B; Azuaje, C; Gavaldà, J; Gomis, X; López, P; Martín, T; Pahissa, A; Ramírez, JL | 1 |
| Acosta, F; Cottagnoud, M; Cottagnoud, P; Täuber, MG | 1 |
| Kaiser, AB; Kernodle, DS; Kourteva, Y; Menzies, BE | 1 |
| Glinka, TW | 1 |
| Hirth, RS; Price, KE; Tsai, YH; Williams, EB | 1 |
| Bodine, JA; Dacey, RG; Sande, MA; Sherertz, RJ; Strausbaugh, LJ; Zak, O | 1 |
| Mandaleris, CD; Sande, MA; Strausbaugh, LJ | 1 |
| Bartlett, JG; Gorbach, SL; Louie, TJ; Onderdonk, AB | 1 |
| Naumann, P | 1 |
| Beck, H; Marre, R; Sack, K; Züllich, B | 1 |
| Heim, H; Rosselet, A; Schluep, J | 1 |
| Barza, M; Murray, T; Pinn, V; Tanguay, P | 1 |
| Murakawa, T; Nishida, M | 1 |
| Gerding, DN; Hall, WH; Kromhout, JP; Sullivan, JJ | 1 |
| Hirano, T; Manabe, T | 1 |
| Ikezawa, Z; Sugihara, Y; Ueno, J | 1 |
| Kamnev, IuV | 1 |
| Henry, NK; Rouse, MS; Steckelberg, JM; Tallan, BM; Wilson, WR | 1 |
| Pechère, JC; Vladoianu, IR | 1 |
| Haruta, T; Kobayashi, Y; Kuroki, S; Okura, K | 1 |
| Lionell, C; Magni, L | 1 |
| Brus-Weijer, L; Krul, AM; Mattie, H; van Dokkum, AM; van Strijen, E | 1 |
| Gill, EA; Norden, CW | 1 |
| Scheld, WM; Tunkel, AR | 1 |
| Beadle, RE; Clarke, CR; Corstvet, RE; Guthrie, AJ; McClure, JR; Nobles, DD; Pawlusiow, J; Short, CR | 1 |
| Jones, CW; Scher, KS; Wroczynski, AF | 1 |
| Bloom, JC; Deldar, A; Lewis, HB; Sellers, TS | 1 |
| Bloom, JC; Deldar, A; Lewis, HB; Morgan, DG; Sellers, TS | 1 |
| Badenoch, PR; Coster, DJ; Hay, GJ; McDonald, PJ | 1 |
| Norrby, SR | 1 |
| Kuder, HV; Wick, WE; Wright, WE | 1 |
| Bailey, RR; Linton, AL; Turnbull, DI | 1 |
| Konícková, L; Prát, V | 1 |
10 review(s) available for cephalosporin c and Disease Models, Animal
| Article | Year |
|---|---|
[Role of ceftaroline fosamil in the treatment of bacteremia and infectious endocarditis].
Topics: Animals; Bacteremia; Ceftaroline; Cephalosporins; Clinical Trials as Topic; Disease Models, Animal; Endocarditis, Bacterial; Humans; Staphylococcal Infections | 2014 |
Ceftobiprole: first cephalosporin with activity against methicillin-resistant Staphylococcus aureus.
Topics: Animals; Cephalosporins; Clinical Trials as Topic; Disease Models, Animal; Drug Interactions; Drug Resistance, Bacterial; Drug Synergism; Humans; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Skin Infections; Time Factors | 2009 |
Ceftobiprole: a new beta-lactam antibiotic.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Clinical Trials as Topic; Diabetic Foot; Disease Models, Animal; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Staphylococcal Infections | 2009 |
Ceftobiprole: in-vivo profile of a bactericidal cephalosporin.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Disease Models, Animal; Drug Resistance, Bacterial; Humans; Mice; Rabbits; Rats | 2006 |
Cephalosporins in adult meningitis.
Topics: Adolescent; Adult; Animals; Bacterial Infections; Cephalosporins; Chloramphenicol; Disease Models, Animal; Humans; Meningitis; Middle Aged; Rabbits | 1984 |
Scope and limitations of experimental chemotherapy.
Topics: Animals; Anti-Bacterial Agents; Blood Proteins; Cephalosporins; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Protein Binding; Species Specificity | 1980 |
Novel cephalosporins for the treatment of MRSA infections.
Topics: Animals; Cephalosporins; Disease Models, Animal; Endocarditis, Bacterial; Methicillin Resistance; Staphylococcal Infections; Staphylococcus aureus | 2002 |
[New methods of administration of cephalosporins and aminoglycosides: relations between pharmacokinetics and pharmacodynamics].
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Injections, Intraperitoneal; Mice; Respiratory Tract Infections; Urinary Tract Infections | 1992 |
Animal models as predictors of outcome of therapy with broad spectrum cephalosporins.
Topics: Animals; Bacterial Infections; Cephalosporins; Disease Models, Animal; Humans; Predictive Value of Tests | 1992 |
Therapy of bacterial meningitis: principles and practice.
Topics: Animals; Anti-Infective Agents; Cephalosporins; Child; Combined Modality Therapy; Dexamethasone; Disease Models, Animal; Drug Administration Schedule; Humans; Infant; Meningitis; Penicillin Resistance | 1989 |
2 trial(s) available for cephalosporin c and Disease Models, Animal
| Article | Year |
|---|---|
Tanshinone I and Tanshinone IIA/B attenuate LPS-induced mastitis via regulating the NF-κB.
Topics: Abietanes; Adult; Animals; Anti-Infective Agents; Apoptosis; Breast Feeding; Cefprozil; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mammary Glands, Animal; Mammary Glands, Human; Mastitis; Mice, Inbred BALB C; NF-kappa B p50 Subunit; Peroxidase; Tumor Necrosis Factor-alpha; Ultrasonography, Mammary | 2021 |
[Microbiological and pharmacological parameters as evaluation criteria for chemotherapeutics].
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Biopharmaceutics; Cephalosporins; Clinical Trials as Topic; Disease Models, Animal; Escherichia coli Infections; Evaluation Studies as Topic; Gentamicins; Humans; Mice; Microbial Sensitivity Tests; Penicillins; Streptococcal Infections; Streptococcus pyogenes | 1977 |
173 other study(ies) available for cephalosporin c and Disease Models, Animal
| Article | Year |
|---|---|
Efficacy of ceftobiprole in a murine model of bacteremia and disseminated infection.
Topics: Animals; Anti-Bacterial Agents; Bacteremia; Cephalosporins; Disease Models, Animal; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus | 2023 |
Abrogation of lysophosphatidic acid receptor 1 ameliorates murine vasculitis.
Topics: Animals; Cell Movement; Cephalosporins; Chemokine CXCL1; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Interleukin-8; Male; Mice; Mice, Inbred C57BL; Neutrophils; Receptors, Lysophosphatidic Acid; Signal Transduction; Vasculitis | 2019 |
Efficacy of human-simulated bronchopulmonary exposures of cefepime, zidebactam and the combination (WCK 5222) against MDR Pseudomonas aeruginosa in a neutropenic murine pneumonia model.
Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; Cefepime; Cephalosporins; Cyclooctanes; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Lung; Mice; Microbial Sensitivity Tests; Neutropenia; Piperidines; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Specific Pathogen-Free Organisms | 2020 |
Mechanistic Insights Into the Differential Efficacy of Daptomycin Plus β-Lactam Combinations Against Daptomycin-Resistant Enterococcus faecium.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; beta-Lactams; Ceftaroline; Cephalosporins; Daptomycin; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus faecium; Ertapenem; Gram-Positive Bacterial Infections; Microbial Sensitivity Tests; Rats; Sequence Alignment; Transcriptome | 2020 |
Expression of CTX-M-15 limits the efficacy of ceftolozane/tazobactam against Escherichia coli in a high-inoculum murine peritonitis model.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; Cephalosporins; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Imipenem; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Peritonitis; Tazobactam | 2020 |
Oral-Only Linezolid-Rifampin Is Highly Effective Compared with Other Antibiotics for Periprosthetic Joint Infection: Study of a Mouse Model.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Daptomycin; Disease Models, Animal; Doxycycline; Drug Combinations; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Prosthesis-Related Infections; Rifampin; Staphylococcal Infections; Treatment Outcome | 2017 |
Effect of Ceftiofur on Hyperalgesia and Allodynia in a Rat Neuropathic Pain Model: The Role of Immune Processes.
Topics: Analgesics; Animals; Cephalosporins; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Gene Expression Regulation; Hyperalgesia; Male; MAP Kinase Signaling System; Neuralgia; NF-kappa B; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha | 2017 |
Efficacy of Cefiderocol against Carbapenem-Resistant Gram-Negative Bacilli in Immunocompetent-Rat Respiratory Tract Infection Models Recreating Human Plasma Pharmacokinetics.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; beta-Lactam Resistance; Cefiderocol; Cephalosporins; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Klebsiella Infections; Klebsiella pneumoniae; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Rats, Sprague-Dawley; Respiratory Tract Infections | 2017 |
Antimicrobial activities of LCB10-0200, a novel siderophore cephalosporin, against the clinical isolates of Pseudomonas aeruginosa and other pathogens.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Disease Models, Animal; Female; Humans; Male; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Sepsis; Siderophores; Skin Diseases, Bacterial; Treatment Outcome; Urinary Tract Infections | 2017 |
Translational Efficacy of Humanized Exposures of Cefepime, Ertapenem, and Levofloxacin against Extended-Spectrum-β-Lactamase-Producing Escherichia coli in a Murine Model of Complicated Urinary Tract Infection.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Disease Models, Animal; Ertapenem; Escherichia coli Infections; Female; Humans; Levofloxacin; Mice, Inbred ICR; Microbial Sensitivity Tests; Urinary Tract Infections; Uropathogenic Escherichia coli | 2017 |
Humanized Exposures of Cefiderocol, a Siderophore Cephalosporin, Display Sustained in vivo Activity against Siderophore-Resistant Pseudomonas aeruginosa.
Topics: Animals; Anti-Bacterial Agents; Azetidines; Cefepime; Cefiderocol; Cephalosporins; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Female; Humans; Levofloxacin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Monobactams; Pseudomonas aeruginosa; Pyridones; Siderophores; Sulfonamides | 2018 |
Cefquinome-loaded microsphere formulations against Klebsiella pneumonia infection during experimental infections.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Cephalosporins; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Host-Pathogen Interactions; Inflammation Mediators; Interleukin-1beta; Interleukin-8; Klebsiella Infections; Klebsiella pneumoniae; Lung; Male; Microspheres; Particle Size; Pneumonia, Bacterial; Polyesters; Rats, Wistar; Surface Properties; Technology, Pharmaceutical; Time Factors; Tumor Necrosis Factor-alpha | 2018 |
Emergence of the third-generation cephalosporin-resistant hypervirulent Klebsiella pneumoniae due to the acquisition of a self-transferable bla
Topics: Animal Structures; Animals; Anti-Bacterial Agents; Bacterial Load; beta-Lactam Resistance; beta-Lactamases; Cephalosporins; Disease Models, Animal; Evolution, Molecular; Gene Transfer, Horizontal; Humans; Klebsiella Infections; Klebsiella pneumoniae; Lepidoptera; Microbial Sensitivity Tests; Plasmids; Survival Analysis; Virulence | 2018 |
Pharmacokinetic changes of cefdinir and cefditoren and its molecular mechanisms in acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Cefdinir; Cephalosporins; Cisplatin; Disease Models, Animal; Gene Expression Regulation; Kidney; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Rats, Wistar; Renal Elimination | 2018 |
In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease.
Topics: Animals; Cephalosporins; Computer Simulation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Lyme Disease; Mice; Mice, Inbred C3H; Molecular Docking Simulation; Structure-Activity Relationship | 2018 |
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ceftazidime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Escherichia coli; Escherichia coli Infections; Hydrolysis; Indicators and Reagents; Mice; Microbial Sensitivity Tests; NADP; Survival Analysis; Treatment Outcome | 2018 |
Cefquinome-Loaded Microsphere Formulations in Protection against Pneumonia with Klebsiella pneumonia Infection and Inflammatory Response in Rats.
Topics: Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cephalosporins; Cytokines; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Delivery Systems; Inflammation; Injections, Intravenous; Klebsiella Infections; Klebsiella pneumoniae; Male; Microspheres; Pneumonia, Bacterial; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar | 2019 |
Efficacy of Ceftaroline Fosamil against Escherichia coli and Klebsiella pneumoniae strains in a rabbit meningitis model.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Ceftaroline; Cephalosporins; Disease Models, Animal; Escherichia coli; Klebsiella Infections; Klebsiella pneumoniae; Meninges; Meningitis, Escherichia coli; Permeability; Rabbits; Treatment Outcome | 2013 |
Ceftobiprole medocaril is an effective treatment against methicillin-resistant Staphylococcus aureus (MRSA) mediastinitis in a rat model.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Disease Models, Animal; Male; Mediastinitis; Methicillin-Resistant Staphylococcus aureus; Rats; Staphylococcal Infections; Sternum | 2014 |
Comparison of efficiency of intravitreal ceftazidime and intravitreal cefepime in the treatment of experimental Pseudomonas aeruginosa endophthalmitis.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Disease Models, Animal; Endophthalmitis; Eye Infections, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Treatment Outcome; Vitreous Body | 2013 |
Pharmacodynamics of cefquinome in a neutropenic mouse thigh model of Staphylococcus aureus infection.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cephalosporins; Disease Models, Animal; Female; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Specific Pathogen-Free Organisms; Staphylococcal Infections; Staphylococcus aureus; Tandem Mass Spectrometry; Thigh | 2014 |
Evaluation of ceftiofur-PHBV microparticles in rats.
Topics: Animals; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Erythrocytes; Injections, Intramuscular; Male; Microbial Sensitivity Tests; Polyesters; Rats; Rats, Sprague-Dawley; Salmonella Infections; Salmonella typhimurium; Structure-Activity Relationship | 2014 |
Hepatocyte growth factor promotes long-term survival and axonal regeneration of retinal ganglion cells after optic nerve injury: comparison with CNTF and BDNF.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cephalosporins; Ciliary Neurotrophic Factor; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Hepatocyte Growth Factor; HSP27 Heat-Shock Proteins; Melphalan; Mesocricetus; Nerve Regeneration; Optic Nerve Injuries; Retinal Ganglion Cells; Time Factors | 2014 |
In vivo efficacy of ceftolozane against Pseudomonas aeruginosa in a rabbit experimental model of pneumonia: comparison with ceftazidime, piperacillin/tazobactam and imipenem.
Topics: Animal Structures; Animals; Anti-Bacterial Agents; Bacterial Load; Ceftazidime; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Female; Humans; Imipenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Treatment Outcome | 2014 |
Ceftaroline-Fosamil efficacy against methicillin-resistant Staphylococcus aureus in a rabbit prosthetic joint infection model.
Topics: Animals; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Disease Models, Animal; Drug Resistance, Bacterial; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Prosthesis-Related Infections; Rabbits; Staphylococcal Infections; Vancomycin | 2014 |
Supporting the ceftaroline fosamil/avibactam Enterobacteriaceae breakpoint determination using humanised in vivo exposures in a thigh model.
Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Ceftaroline; Cephalosporins; Disease Models, Animal; Enterobacter cloacae; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Reproducibility of Results; Thigh | 2014 |
Efficacy of cefepime, ertapenem and norfloxacin against leptospirosis and for the clearance of pathogens in a hamster model.
Topics: Animal Structures; Animals; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Cricetinae; Disease Models, Animal; Ertapenem; Histocytochemistry; Leptospira interrogans serovar autumnalis; Leptospirosis; Norfloxacin; Survival Analysis; Treatment Outcome | 2014 |
Evaluation of the efficiency of cefoxitin/cefepime combination against Enterobacteriaceae resistant to expanded-spectrum cephalosporins.
Topics: Animal Structures; Animals; Bacterial Load; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cefoxitin; Cephalosporins; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Mice; Microbial Sensitivity Tests; Survival Analysis; Treatment Outcome | 2015 |
In vivo evaluation of mutant selection window of cefquinome against Escherichia coli in piglet tissue-cage model.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Diffusion Chambers, Culture; Disease Models, Animal; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Microbial Sensitivity Tests; Mutation; Swine | 2014 |
[Prophylaxis of purulent complications in mechanical ileus].
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Biological Transport; Cephalosporins; Ciprofloxacin; Disease Models, Animal; Fluoroquinolones; Gentamicins; Ileus; Peritonitis; Permeability; Rats; Rats, Wistar | 2015 |
Experimental study of cerebrospinal fluid tumor necrosis factor-alpha release in penicillin- and cephalosporin-resistant pneumococcal meningitis treated with different antibiotic schedules.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; beta-Lactam Resistance; Cephalosporins; Cerebrospinal Fluid; Dexamethasone; Disease Models, Animal; Female; Meningitis, Pneumococcal; Penicillins; Rabbits; Streptococcus pneumoniae; Tumor Necrosis Factor-alpha | 2017 |
In Vivo Pharmacodynamics of Cefquinome in a Neutropenic Mouse Thigh Model of Streptococcus suis Serotype 2 at Varied Initial Inoculum Sizes.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Streptococcal Infections; Streptococcus suis; Thigh | 2016 |
Targeted synthesis of novel β-lactam antibiotics by laccase-catalyzed reaction of aromatic substrates selected by pre-testing for their antimicrobial and cytotoxic activity.
Topics: Animals; Anti-Infective Agents; beta-Lactamases; beta-Lactams; Biotransformation; Catalysis; Cephalosporins; Culture Media; Disease Models, Animal; Enterococcus; Female; Gram-Positive Bacteria; Hydroquinones; Industrial Microbiology; Laccase; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Penicillins; Staphylococcal Infections; Staphylococcus | 2016 |
Pharmacokinetics of Ceftiofur Crystalline-Free Acid in Clinically Healthy Dogs (Canis lupus familiaris).
Topics: Animals; Anti-Bacterial Agents; Bacteria; Cephalosporins; Disease Models, Animal; Dogs; Female; Half-Life; Male; Microbial Sensitivity Tests | 2016 |
In Vivo Pharmacokinetics/Pharmacodynamics of Cefquinome in an Experimental Mouse Model of Staphylococcus Aureus Mastitis following Intramammary Infusion.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cattle; Cephalosporins; Disease Models, Animal; Female; Injections; Mastitis; Mice; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome | 2016 |
The contribution of antibiotics, pneumonia and the immune response to stroke outcome.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Body Temperature; Body Weight; Cephalosporins; Cytokines; Disease Models, Animal; Enrofloxacin; Fluoroquinolones; Lymphocytes; Male; Myelin Basic Protein; Nervous System Diseases; Pneumonia; Rats; Rats, Inbred Lew; Staphylococcus aureus; Statistics, Nonparametric; Stroke | 2016 |
Novel broad-spectrum and long-acting parenteral cephalosporins having an acyl cyanamide moiety at the C-3 terminal: Synthesis and structure-activity relationships.
Topics: Animals; Anti-Infective Agents; Bacteria; Cephalosporins; Cyanamide; Disease Models, Animal; Half-Life; Haplorhini; Male; Mice; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2016 |
Application of chitosan microparticles for treatment of metritis and in vivo evaluation of broad spectrum antimicrobial activity in cow uteri.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteroidaceae Infections; Cattle; Cephalosporins; Chitosan; Disease Models, Animal; Female; Fusobacteriaceae Infections; Fusobacterium necrophorum; Humans; Treatment Outcome; Uterine Diseases; Uterus | 2016 |
In Vitro-In Vivo Discordance with Humanized Piperacillin-Tazobactam Exposures against Piperacillin-Tazobactam-Resistant/Pan-β-Lactam-Susceptible Escherichia coli.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Colistin; Culture Media; Disease Models, Animal; Drug Administration Schedule; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tobramycin; Treatment Outcome | 2016 |
Efficacy of ceftaroline versus vancomycin in an experimental foreign-body and systemic infection model caused by biofilm-producing methicillin-resistant Staphylococcus epidermidis.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Biofilms; Ceftaroline; Cephalosporins; Disease Models, Animal; Female; Foreign Bodies; Methicillin Resistance; Mice, Inbred C57BL; Microbial Sensitivity Tests; Random Allocation; Sepsis; Soft Tissue Infections; Staphylococcal Infections; Staphylococcus epidermidis; Treatment Outcome; Vancomycin | 2016 |
In vivo pharmacodynamics of ceftobiprole against multiple bacterial pathogens in murine thigh and lung infection models.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Cephalosporin Resistance; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Enterobacteriaceae Infections; Extremities; Female; Gram-Negative Bacterial Infections; Lung Diseases; Methicillin Resistance; Mice; Mice, Inbred ICR; Neutropenia; Penicillin Resistance; Pneumococcal Infections; Staphylococcal Infections; Staphylococcus aureus | 2008 |
Ceftiofur regulates LPS-induced production of cytokines and improves LPS-induced survival rate in mice.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Cytokines; Disease Models, Animal; Endotoxemia; Female; Interleukin-10; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Time Factors; Tumor Necrosis Factor-alpha | 2008 |
Dose related effect of systemic antibiotics in prevention of postoperative intra-abdominal adhesion formation in experimental animals.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cricetinae; Disease Models, Animal; Injections, Intramuscular; Laparotomy; Mesocricetus; Metronidazole; Postoperative Complications; Random Allocation; Time Factors; Tissue Adhesions; Treatment Outcome | 2008 |
Identifying exposure targets for treatment of staphylococcal pneumonia with ceftobiprole.
Topics: Adult; Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cephalosporins; Disease Models, Animal; Epithelium; Female; Humans; Mice; Monte Carlo Method; Pneumonia, Staphylococcal | 2009 |
Ceftobiprole is superior to vancomycin, daptomycin, and linezolid for treatment of experimental endocarditis in rabbits caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Cephalosporins; Chromatography, High Pressure Liquid; Daptomycin; Disease Models, Animal; Endocarditis, Bacterial; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Rabbits; Random Allocation; Vancomycin | 2010 |
Quantitative assessment of combination antimicrobial therapy against multidrug-resistant bacteria in a murine pneumonia model.
Topics: Acinetobacter baumannii; Amikacin; Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Lung; Mice; Ofloxacin; Pneumonia, Bacterial; Polymerase Chain Reaction; Pseudomonas aeruginosa; Random Allocation; Survival Analysis | 2010 |
Efficacy of the new cephalosporin ceftaroline in the treatment of experimental methicillin-resistant Staphylococcus aureus acute osteomyelitis.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bone and Bones; Bone Marrow; Ceftaroline; Cephalosporins; Disease Models, Animal; Female; Linezolid; Methicillin-Resistant Staphylococcus aureus; Osteomyelitis; Oxazolidinones; Rabbits; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2010 |
Enhanced in vivo activity of cefditoren in pre-immunized mice against penicillin-resistant S. pneumoniae (serotypes 6B, 19F and 23F) in a sepsis model.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Antibody Specificity; Cephalosporins; Disease Models, Animal; Female; HL-60 Cells; Humans; Immunization; Immunization, Passive; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Penicillin Resistance; Phagocytes; Phagocytosis; Sepsis; Serotyping; Streptococcus pneumoniae; Vaccines, Inactivated | 2010 |
Evaluation of the in vivo efficacy of intramuscularly administered ceftaroline fosamil, a novel cephalosporin, against a methicillin-resistant Staphylococcus aureus strain in a rabbit endocarditis model.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Ceftaroline; Cephalosporins; Disease Models, Animal; Endocarditis, Bacterial; Endocardium; Female; Injections, Intramuscular; Methicillin-Resistant Staphylococcus aureus; Rabbits; Staphylococcal Infections; Treatment Outcome | 2010 |
Comparison of ceftaroline fosamil, daptomycin and tigecycline in an experimental rabbit endocarditis model caused by methicillin-susceptible, methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Colony Count, Microbial; Daptomycin; Disease Models, Animal; Drug Resistance, Bacterial; Endocarditis, Bacterial; Female; Methicillin-Resistant Staphylococcus aureus; Microbial Viability; Minocycline; Rabbits; Rodent Diseases; Staphylococcal Infections; Tigecycline; Treatment Outcome | 2011 |
[Assessment of efficacies of imipenem, cefoperazone-sulbactam and cefepime in rats with experimental thigh abscess model with multidrug resistant and susceptible Acinetobacter baumannii strains].
Topics: Abscess; Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Cefepime; Cefoperazone; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Combinations; Drug Resistance, Multiple, Bacterial; Female; Imipenem; Random Allocation; Rats; Rats, Wistar; Serum Bactericidal Test; Soft Tissue Infections; Sulbactam; Thigh | 2011 |
In vivo comparison of CXA-101 (FR264205) with and without tazobactam versus piperacillin-tazobactam using human simulated exposures against phenotypically diverse gram-negative organisms.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Combinations; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thigh | 2012 |
Evaluation of ceftobiprole activity against a variety of gram-negative pathogens, including Escherichia coli, Haemophilus influenzae (β-lactamase positive and β-lactamase negative), and Klebsiella pneumoniae, in a rabbit meningitis model.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Disease Models, Animal; Escherichia coli; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Haemophilus influenzae; Klebsiella pneumoniae; Meningitis, Bacterial; Microbial Sensitivity Tests; Rabbits; Treatment Outcome | 2012 |
Efficacy of doripenem against Escherichia coli and Klebsiella pneumoniae in experimental meningitis.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Carbapenems; Cefepime; Cephalosporins; Disease Models, Animal; Doripenem; Escherichia coli; Escherichia coli Infections; Klebsiella Infections; Klebsiella pneumoniae; Meningitis, Bacterial; Rabbits; Treatment Outcome | 2012 |
The intramammary efficacy of first generation cephalosporins against Staphylococcus aureus mastitis in mice.
Topics: Animals; Anti-Infective Agents; Cattle; Cephalosporins; Disease Models, Animal; Female; Lactation; Mastitis, Bovine; Mice; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus | 2012 |
Efficacy of ceftolozane in a murine model of Pseudomonas aeruginosa acute pneumonia: in vivo antimicrobial activity and impact on host inflammatory response.
Topics: Acute Disease; Animals; Anti-Infective Agents; Ceftazidime; Cephalosporins; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Inflammation; Mice; Microbial Sensitivity Tests; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Treatment Outcome | 2013 |
Protein synthesis inhibiting clindamycin improves outcome in a mouse model of Staphylococcus aureus sepsis compared with the cell wall active ceftriaxone.
Topics: Animals; Anti-Bacterial Agents; Ceftriaxone; Cell Wall; Cephalosporins; Clindamycin; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Protein Synthesis Inhibitors; Sepsis; Staphylococcal Infections; Treatment Outcome | 2002 |
Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation.
Topics: Animals; Ceftriaxone; Cephalosporins; Disease Models, Animal; Disease Susceptibility; Drosophila Proteins; Inflammation; Listeria monocytogenes; Listeriosis; Membrane Glycoproteins; Meningitis, Bacterial; Mice; Mice, Inbred C57BL; Mice, Knockout; Pneumococcal Infections; Receptors, Cell Surface; Streptococcus pneumoniae; Time Factors; Toll-Like Receptor 2; Toll-Like Receptors | 2002 |
Anti-MRSA cephems. Part 2: C-7 cinnamic acid derivatives.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Cinnamates; Disease Models, Animal; Lethal Dose 50; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship; Toxicity Tests, Acute | 2003 |
Anti-MRSA cephems. Part 3: additional C-7 acid derivatives.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Disease Models, Animal; Lethal Dose 50; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship | 2003 |
A comparison of antibiotic regimens in the treatment of acute melioidosis in a mouse model.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Ceftazidime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Melioidosis; Mice; Mice, Inbred BALB C; Trimethoprim, Sulfamethoxazole Drug Combination | 2003 |
Pancreatic concentrations of cefepime in experimental necrotizing pancreatitis.
Topics: Animals; Antimetabolites; Cefepime; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Ethionine; Injections, Intramuscular; Male; Pancreatitis, Acute Necrotizing; Rabbits; Tissue Distribution | 2003 |
Relevance of antimicrobial agent-induced endotoxin release from in vitro cultured Escherichia coli and in vivo experimental infection with Gram-negative bacilli.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Disease Models, Animal; Endotoxins; Escherichia coli; Escherichia coli Infections; Gentamicins; Humans; Male; Monocytes; Peritonitis; Rabbits; Tumor Necrosis Factor-alpha | 2003 |
Simultaneous intravenous and intramiddle-ear dosing to determine cefditoren influx and efflux clearances in middle ear fluid in freely moving chinchillas.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Biological Transport; Cephalosporins; Chinchilla; Disease Models, Animal; Ear, Middle; Injections, Intravenous; Instillation, Drug; Male; Microdialysis; Otitis Media; Time Factors | 2003 |
In vitro antimicrobial activity of T-91825, a novel anti-MRSA cephalosporin, and in vivo anti-MRSA activity of its prodrug, TAK-599.
Topics: Animals; Butyrates; Ceftaroline; Cephalosporins; Disease Models, Animal; Enterococcus; Male; Methicillin Resistance; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Microbial Sensitivity Tests; Oxazoles; Pneumonia, Bacterial; Staphylococcal Infections; Staphylococcus | 2004 |
Comparison of 99mTc-DTPA and urea for measuring cefepime concentrations in epithelial lining fluid.
Topics: Analysis of Variance; Animals; Biological Availability; Biological Transport, Active; Bronchoalveolar Lavage Fluid; Cefepime; Cephalosporins; Disease Models, Animal; Dogs; Epithelium; Female; Infusions, Intravenous; Male; Pneumonia; Radiopharmaceuticals; Sensitivity and Specificity; Technetium Tc 99m Pentetate; Urea | 2004 |
Comparison of in vivo intrinsic activity of cefepime and imipenem in a Pseudomonas aeruginosa rabbit endocarditis model: effect of combination with tobramycin simulating human serum pharmacokinetics.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Endocarditis, Bacterial; Female; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Tobramycin | 2004 |
Infection prophylaxis of gunshot wounds using probiotics.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Anti-Bacterial Agents; Bacillus subtilis; Bacterial Translocation; Bacterial Vaccines; Cefazolin; Cephalosporins; Disease Models, Animal; Drug Evaluation, Preclinical; Infection Control; Injections, Intramuscular; Probiotics; Rabbits; Random Allocation; Single-Blind Method; Surgical Wound Infection; Therapeutic Irrigation; Treatment Outcome; Wounds, Gunshot | 2004 |
Evaluation of ceftobiprole in a rabbit model of aortic valve endocarditis due to methicillin-resistant and vancomycin-intermediate Staphylococcus aureus.
Topics: Animals; Aortic Valve; Cephalosporins; Disease Models, Animal; Endocarditis, Bacterial; Heart Valve Diseases; Methicillin Resistance; Microbial Sensitivity Tests; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2005 |
Efficacy of cefepime and imipenem in experimental murine pneumonia caused by porin-deficient Klebsiella pneumoniae producing CMY-2 beta-Lactamase.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Disease Models, Animal; Female; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Pneumonia, Bacterial; Porins; Treatment Outcome | 2005 |
Microdialysis studies of the distribution of antibiotics into chinchilla middle ear fluid.
Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Cefdinir; Cephalosporins; Chinchilla; Disease Models, Animal; Dose-Response Relationship, Drug; Ear, Middle; Half-Life; Microbial Sensitivity Tests; Microdialysis; Otitis Media; Streptococcus pneumoniae | 2005 |
Comparative epileptogenic activity of various cephalosporins in rats.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Convulsants; Disease Models, Animal; Injections, Intraventricular; Male; Rats; Rats, Wistar; Seizures; Structure-Activity Relationship | 1989 |
New ideas for therapy in ALS: critical considerations.
Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; beta-Lactams; Ceftriaxone; Cephalosporins; Clinical Trials as Topic; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Humans; Mice; Mice, Transgenic | 2006 |
Pharmacodynamics of RWJ-54428 against Staphylococcus aureus, Streptococcus pneumoniae, and Enterococcus faecalis in a neutropenic mouse thigh infection model.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Disease Models, Animal; Enterococcus faecalis; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Male; Mice; Microbial Sensitivity Tests; Neutropenia; Staphylococcus aureus; Streptococcus pneumoniae; Thigh; Treatment Outcome | 2008 |
Efficacies of ceftobiprole medocaril and comparators in a rabbit model of osteomyelitis due to methicillin-resistant Staphylococcus aureus.
Topics: Animals; Body Weight; Cephalosporins; Disease Models, Animal; Methicillin Resistance; Microbial Sensitivity Tests; Osteomyelitis; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tibia | 2008 |
Experimental study of meropenem in the therapy of cephalosporin-susceptible and -resistant pneumococcal meningitis.
Topics: Animals; Cephalosporin Resistance; Cephalosporins; Disease Models, Animal; Guinea Pigs; Meningitis, Bacterial; Meningitis, Pneumococcal; Meropenem; Microbial Sensitivity Tests; Rabbits; Streptococcus pneumoniae; Thienamycins | 2008 |
Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Cross Infection; Disease Models, Animal; Drug Resistance, Bacterial; Female; Humans; Methicillin Resistance; Mice; Mice, Inbred BALB C; Phenotype; Pneumonia, Staphylococcal; Staphylococcus aureus | 2008 |
Moxalactam penetration of normal and osteomyelitic bone.
Topics: Animals; Bone and Bones; Capillary Permeability; Cephalosporins; Cephamycins; Disease Models, Animal; Dogs; Kinetics; Mathematics; Moxalactam; Osteomyelitis | 1983 |
Pharmacokinetics and bacteriological efficacy of moxalactam (LY127935), netilmicin, and ampicillin in experimental gram-negative enteric bacillary meningitis.
Topics: Ampicillin; Animals; Bacteria; Bacterial Infections; Cephalosporins; Cephamycins; Disease Models, Animal; Gentamicins; Male; Meningitis; Moxalactam; Netilmicin; Rabbits; Species Specificity | 1980 |
Gentamicin and cefsulodin efficacy in a rat abscess model.
Topics: Abscess; Anaerobiosis; Animals; Cefsulodin; Cephalosporins; Disease Models, Animal; Female; Gentamicins; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Rats | 1982 |
Prophylactic activity of cephalosporins in a mouse model of surgical wound infection.
Topics: Animals; Cefamandole; Cefonicid; Cephalosporins; Disease Models, Animal; Leukocyte Count; Mice; Surgical Wound Infection | 1983 |
[An experimental production of suppurative otitis media in dog, and a trial to evaluate the therapeutic effect of cefmetazole on this otitis media].
Topics: Animals; Anti-Bacterial Agents; Cefmetazole; Cephalosporins; Cephamycins; Disease Models, Animal; Dogs; Ear, Middle; Otitis Media; Otitis Media, Suppurative | 1982 |
Importance of beta-lactamase inactivation in treatment of experimental endocarditis caused by Staphylococcus aureus.
Topics: Animals; beta-Lactamases; Cefazolin; Cephaloridine; Cephalosporins; Cephalothin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Endocarditis, Bacterial; Enzyme Activation; Female; Male; Microbial Sensitivity Tests; Rabbits; Staphylococcal Infections; Staphylococcus aureus | 1980 |
Evaluation of eight cephalosporins in hamster colitis model.
Topics: Animals; Cecal Diseases; Cecum; Cephalosporins; Clindamycin; Clostridium; Cricetinae; Disease Models, Animal; Enterocolitis, Pseudomembranous; Feces; Gastrointestinal Hemorrhage; Inflammation; Male; Mesocricetus | 1981 |
Therapeutic effects of cefotiam and cefazolin on experimental pneumonia caused by Klebsiella pneumoniae DT-S in mice.
Topics: Animals; Cefazolin; Cefotiam; Cephalosporins; Disease Models, Animal; Drug Administration Schedule; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Male; Mice; Pneumonia | 1980 |
Failure of time-kill synergy studies using subinhibitory antimicrobial concentrations to predict in vivo antagonism of cephalosporin-rifampin combinations against Staphylococcus aureus.
Topics: Animals; Cefazolin; Cefpirome; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Endocarditis, Bacterial; Gentamicins; Microbial Sensitivity Tests; Nafcillin; Predictive Value of Tests; Rabbits; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 1994 |
Efficacy of a novel injectable cephalosporin, Cefclidin, on the experimental complicated urinary tract infections with urinary stones caused by Pseudomonas aeruginosa and Proteus mirabilis.
Topics: Animals; Cephalosporins; Disease Models, Animal; Drug Resistance, Microbial; Female; Imipenem; Kidney Calculi; Proteus Infections; Proteus mirabilis; Pseudomonas Infections; Rats; Rats, Sprague-Dawley; Urinary Bladder Calculi; Urinary Calculi; Urinary Tract Infections | 1994 |
Evaluation of antimicrobial regimens for treatment of experimental penicillin- and cephalosporin-resistant pneumococcal meningitis.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cefpirome; Ceftriaxone; Cephalosporins; Disease Models, Animal; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Fluoroquinolones; Male; Meningitis, Pneumococcal; Meropenem; Microbial Sensitivity Tests; Penicillin Resistance; Quinolones; Rabbits; Rifampin; Thienamycins; Vancomycin | 1993 |
Evaluation of bacterial interference and beta-lactamase production in management of experimental infection with group A beta-hemolytic streptococci.
Topics: Abscess; Animals; beta-Lactamases; Cefprozil; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Female; Hemolysis; Mice; Mice, Inbred Strains; Penicillins; Staphylococcus aureus; Streptococcal Infections; Streptococcus agalactiae; Tonsillitis | 1993 |
Pharmacokinetics of newer cephalosporins after subconjunctival and intravitreal injection in rabbits.
Topics: Animals; Cefepime; Ceftazidime; Ceftizoxime; Ceftriaxone; Cephalosporins; Colony Count, Microbial; Conjunctiva; Disease Models, Animal; Endophthalmitis; Eye Infections, Bacterial; Half-Life; Rabbits; Staphylococcal Infections; Vitreous Body | 1993 |
Dilemmas in diagnosis and management of cephalosporin-resistant Streptococcus pneumoniae meningitis.
Topics: Animals; Cephalosporins; Disease Models, Animal; Drug Resistance, Microbial; Humans; Infant; Male; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Penicillin Resistance; Rabbits; Streptococcus pneumoniae | 1993 |
Comparative treatment of experimental Staphylococcus aureus endophthalmitis.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cefazolin; Cephalosporins; Combined Modality Therapy; Disease Models, Animal; Drug Therapy, Combination; Endophthalmitis; Eye Infections, Bacterial; Methylprednisolone; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Vitrectomy; Vitreous Body | 1996 |
Impact of different classes antimicrobial agents on plasma endotoxin activity.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Blood Pressure; Cefotaxime; Cephalosporins; Ciprofloxacin; Colony Count, Microbial; Disease Models, Animal; Endotoxins; Escherichia coli; Escherichia coli Infections; Gentamicins; Imipenem; Male; Peritoneal Diseases; Peritoneum; Rats; Rats, Wistar; Thienamycins | 1996 |
Experimental endogenous septicaemia caused by Klebsiella pneumoniae and Escherichia coli in mice.
Topics: Ampicillin; Animals; Bacteremia; Ceftazidime; Cephalosporins; Cyclophosphamide; Disease Models, Animal; Escherichia coli Infections; Fluorouracil; Immunosuppressive Agents; Klebsiella Infections; Klebsiella pneumoniae; Male; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Penicillins; Pseudomonas Infections; Survival Analysis | 1996 |
[Model of a miniature pig catheterized for pharmacokinetic and pharmacodynamic studies of anti-infective agents].
Topics: Adult; Animals; Antibiotics, Antitubercular; Antifungal Agents; Catheterization, Peripheral; Cefepime; Cefpirome; Ceftriaxone; Cephalosporins; Disease Models, Animal; Female; Humans; Injections, Intravenous; Meropenem; Swine; Thienamycins | 1996 |
Correlation of in-vitro activity and pharmacokinetic parameters with in-vivo effect of amoxycillin, co-amoxiclav and cefotaxime in a murine model of pneumococcal pneumonia.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Cefotaxime; Cephalosporins; Clavulanic Acids; Disease Models, Animal; Drug Therapy, Combination; Female; Mice; Microbial Sensitivity Tests; Penicillins; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 1996 |
Amelioration by cAMP of cephaloridine-induced injury in the porcine kidney cell line LLC-PK1.
Topics: Acute Kidney Injury; Animals; Bucladesine; Cephaloridine; Cephalosporins; Disease Models, Animal; L-Lactate Dehydrogenase; Lipid Peroxidation; LLC-PK1 Cells; Swine | 1996 |
Intraocular dexamethasone produces a harmful effect on treatment of experimental Staphylococcus aureus endophthalmitis.
Topics: Animals; Cefazolin; Cephalosporins; Chemotherapy, Adjuvant; Choroiditis; Corneal Opacity; Dexamethasone; Disease Models, Animal; Endophthalmitis; Eye Diseases; Eye Infections, Bacterial; Glucocorticoids; Methylprednisolone; Necrosis; Rabbits; Retina; Staphylococcal Infections; Staphylococcus aureus; Vitrectomy | 1996 |
Development of experimental pneumonia by infection with penicillin-insensitive Streptococcus pneumoniae in guinea pigs and their treatment with amoxicillin, cefotaxime, and meropenem.
Topics: Amoxicillin; Animals; Cefotaxime; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Female; Guinea Pigs; Lung; Meropenem; Penicillin Resistance; Penicillins; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Thienamycins | 1996 |
Efficacies of cefotaxime and ceftriaxone in a mouse model of pneumonia induced by two penicillin- and cephalosporin-resistant strains of Streptococcus pneumoniae.
Topics: Amoxicillin; Animals; Cefotaxime; Ceftriaxone; Cephalosporin Resistance; Cephalosporins; Disease Models, Animal; Female; Lung; Mice; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 1996 |
Experimental pseudomonal posttraumatic endophthalmitis in a swine model. Treatment with ceftazidime, amikacin, and imipenem.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Disease Models, Animal; Endophthalmitis; Eye Infections, Bacterial; Eye Injuries, Penetrating; Follow-Up Studies; Imipenem; Injections; Pseudomonas aeruginosa; Pseudomonas Infections; Sclera; Swine; Thienamycins; Vitreous Body | 1997 |
Trovafloxacin delays the antibiotic-induced inflammatory response in experimental pneumococcal meningitis.
Topics: Adult; Animals; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Disease Models, Animal; Fluoroquinolones; Humans; Injections, Intravenous; Interleukin-1; Lactic Acid; Meningitis, Pneumococcal; Naphthyridines; Rabbits; Streptococcus pneumoniae; Tumor Necrosis Factor-alpha | 1997 |
[In vivo pharmacokinetic of amikacin and its pharmacodynamic in combination with cefepime, cefpirome and meropenem in an in vitro/ex vivo micropig model].
Topics: Amikacin; Animals; Anti-Bacterial Agents; Cefepime; Cefpirome; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Klebsiella pneumoniae; Meropenem; Perfusion; Serum Bactericidal Test; Swine; Thienamycins | 1997 |
A critical role of tumor necrosis factor (TNF) alpha in experimental group A streptococcal (GAS) bacteremia.
Topics: Animals; Antibodies, Monoclonal; Bacteremia; Ceftriaxone; Cephalosporins; Cytokines; Disease Models, Animal; Female; Humans; Lymphotoxin-alpha; Male; Papio; Streptococcal Infections; Streptococcus pyogenes | 1997 |
Therapeutic efficacy of intravitreal ceftazidime, imipenem, and amikacin in a swine model of posttraumatic Pseudomonas aeruginosa endophthalmitis.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Disease Models, Animal; Endophthalmitis; Eye Infections, Bacterial; Eye Injuries, Penetrating; Imipenem; Pseudomonas Infections; Swine; Vitreous Body | 1997 |
Predictive value of several signs of infection as surrogate markers for mortality in a neutropenic guinea pig model of Pseudomonas aeruginosa sepsis.
Topics: Animals; Anti-Bacterial Agents; Biomarkers; Ceftazidime; Cephalosporins; Diarrhea; Disease Models, Animal; Female; Guinea Pigs; Imipenem; Meropenem; Movement Disorders; Neutropenia; Predictive Value of Tests; Pseudomonas Infections; Regression Analysis; Respiration; Thienamycins; Time Factors; Tobramycin; Weight Loss | 1997 |
Staphylococcal septic arthritis: antibiotic and nonsteroidal anti-inflammatory drug treatment in a rabbit model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Cartilage, Articular; Ceftriaxone; Cephalosporins; Dinoprostone; Disease Models, Animal; Drug Therapy, Combination; Female; Glycosaminoglycans; Hydroxyproline; Knee Joint; Naproxen; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Synovial Fluid; Synovitis | 1997 |
The role of prophylactic antibiotics in spinal instrumentation. A rabbit model.
Topics: Animals; Antibiotic Prophylaxis; Cefazolin; Cephalosporins; Disease Models, Animal; Intervertebral Disc; Postoperative Complications; Prospective Studies; Rabbits; Reproducibility of Results; Spinal Fusion; Staphylococcal Infections; Staphylococcus aureus | 1998 |
Cefepime and amikacin synergy in vitro and in vivo against a ceftazidime-resistant strain of Enterobacter cloacae.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Colony Count, Microbial; Creatinine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enterobacter cloacae; Enterobacteriaceae Infections; Lung; Microbial Sensitivity Tests; Pneumonia, Bacterial; Rats; Rats, Mutant Strains; Time Factors; Treatment Outcome | 1998 |
[Therapeutic effect of cefluprenam on polymicrobial urinary tract infection associated with Enterococcus faecalis, using the infectious urolithiasis model in rats].
Topics: Animals; Ceftazidime; Cephalosporins; Disease Models, Animal; Enterococcus faecalis; Female; Gram-Positive Bacterial Infections; Proteus Infections; Proteus mirabilis; Pseudomonas Infections; Rats; Rats, Sprague-Dawley; Urinary Calculi; Urinary Tract Infections | 1998 |
[Aminopenicillins verses cephalosporins in the treatment of pneumonia by pneumococci resistant to penicillin: animal model].
Topics: Animals; Cephalosporins; Disease Models, Animal; Penicillin Resistance; Penicillins; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 1998 |
Successful treatment of murine listeriosis and salmonellosis with levofloxacin.
Topics: Animals; Anti-Infective Agents; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Levofloxacin; Listeria monocytogenes; Listeriosis; Mice; Ofloxacin; Penicillins; Salmonella Infections, Animal; Salmonella typhimurium | 1998 |
[Characteristics of etiotropic therapy of plaque infection induced by atypical strains of F1- phenotype plaque microbe].
Topics: Aminoglycosides; Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antigens, Bacterial; Aztreonam; Bacterial Proteins; Cephalosporins; Disease Models, Animal; Doxycycline; Fluoroquinolones; Mice; Monobactams; Penicillins; Phenotype; Plague; Rifampin | 1998 |
Role of neutrophil elastase in stress-induced gastric mucosal injury in rats.
Topics: Animals; Capillary Permeability; Cephalosporins; Disease Models, Animal; Gastric Mucosa; Glycine; Leukocyte Elastase; Leukopenia; Male; Mechlorethamine; Neutrophils; Peptic Ulcer; Peroxidase; Rats; Rats, Wistar; Restraint, Physical; Serine Proteinase Inhibitors; Specific Pathogen-Free Organisms; Stress, Physiological; Sulfonamides | 1998 |
Pharmacodynamics of trovafloxacin in a mouse model of cephalosporin-resistant Streptococcus pneumoniae pneumonia.
Topics: Analysis of Variance; Animals; Anti-Infective Agents; Cephalosporin Resistance; Cephalosporins; Disease Models, Animal; Female; Fluoroquinolones; Lung; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Naphthyridines; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 1999 |
Antimicrobial treatment of an experimental otitis media caused by a beta-lactamase positive isolate of Haemophilus influenzae.
Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; beta-Lactamases; Cefuroxime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Female; Gerbillinae; Haemophilus Infections; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Otitis Media with Effusion; Treatment Outcome | 1999 |
Treatment of experimental pneumonia in rats caused by a PER-1 extended-spectrum beta-lactamase-producing strain of Pseudomonas aeruginosa.
Topics: Amikacin; Animals; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Imipenem; Lung; Male; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Rats, Wistar | 1999 |
Combination antimicrobial therapy of acute Burkholderia pseudomallei infection in a mouse model.
Topics: Animals; Burkholderia pseudomallei; Cefpirome; Ceftazidime; Cephalosporins; Chloramphenicol; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Liver; Melioidosis; Mice; Mice, Inbred BALB C; Spleen; Trimethoprim, Sulfamethoxazole Drug Combination | 1999 |
Lower lipoteichoic and teichoic acid CSF concentrations during treatment of pneumococcal meningitis with non-bacteriolytic antibiotics than with ceftriaxone.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ceftriaxone; Cephalosporins; Disease Models, Animal; Fluoroquinolones; Immunoenzyme Techniques; Lipopolysaccharides; Meningitis, Pneumococcal; Moxifloxacin; Naphthyridines; Polysaccharides, Bacterial; Quinolines; Rabbits; Reference Values; Rifabutin; Teichoic Acids; Virginiamycin | 1999 |
In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.
Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Clarithromycin; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Mice; Microbial Sensitivity Tests; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors | 2000 |
Role of Streptococcus pneumoniae and Haemophilus influenzae in the development of acute otitis media and otitis media with effusion in a gerbil model.
Topics: Acute Disease; Amoxicillin-Potassium Clavulanate Combination; Animals; Cefuroxime; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Therapy, Combination; Female; Gerbillinae; Haemophilus Infections; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Otitis Media; Otitis Media with Effusion; Pneumococcal Infections; Streptococcus pneumoniae | 2000 |
Gemifloxacin is effective in experimental pneumococcal meningitis.
Topics: Animals; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Cerebrospinal Fluid; Disease Models, Animal; Fluoroquinolones; Gemifloxacin; Hippocampus; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Naphthyridines; Neurons; Rabbits; Streptococcus pneumoniae | 2000 |
Meropenem alone and in combination with vancomycin in experimental meningitis caused by a penicillin-resistant pneumococcal strain.
Topics: Animals; Ceftriaxone; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Therapy, Combination; Meningitis, Pneumococcal; Meropenem; Microbial Sensitivity Tests; Penicillin Resistance; Rabbits; Streptococcus pneumoniae; Thienamycins; Vancomycin | 1999 |
Pharmacodynamic assessment of cefprozil against Streptococcus pneumoniae: implications for breakpoint determinations.
Topics: Animals; Cefprozil; Cephalosporins; Disease Models, Animal; Female; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Pneumococcal Infections; Streptococcus pneumoniae; Treatment Outcome | 2000 |
Evaluation in an animal model and in vitro of the combination clavulanic acid and cephalosporins against beta-lactamase producing and nonproducing Staphylococcus aureus strains.
Topics: Animals; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; Ceftriaxone; Cephalexin; Cephalosporin Resistance; Cephalosporins; Clavulanic Acid; Disease Models, Animal; Drug Therapy, Combination; Male; Microbial Sensitivity Tests; Rats; Rats, Wistar; Staphylococcus aureus | 2000 |
Quinupristin-dalfopristin combined with beta-lactams for treatment of experimental endocarditis due to Staphylococcus aureus constitutively resistant to macrolide-lincosamide-streptogramin B antibiotics.
Topics: Animals; Anti-Bacterial Agents; Cefamandole; Cefepime; Cephalosporins; Disease Models, Animal; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Endocarditis, Bacterial; Humans; Lincosamides; Macrolides; Microbial Sensitivity Tests; Rats; Staphylococcal Infections; Staphylococcus aureus; Time Factors; Virginiamycin | 2000 |
Synergy between trovafloxacin and ceftriaxone against penicillin-resistant pneumococci in the rabbit meningitis model and in vitro.
Topics: Animals; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fluoroquinolones; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Naphthyridines; Penicillin Resistance; Pneumococcal Infections; Rabbits; Streptococcus pneumoniae | 2000 |
Concentration-dependent selection of small phenotypic differences in TEM beta-lactamase-mediated antibiotic resistance.
Topics: Animals; beta-Lactam Resistance; beta-Lactamases; Cefotaxime; Cell Division; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Escherichia coli; Mice; Models, Biological; Phenotype; Porins; Selection, Genetic | 2000 |
Antibacterial properties of Pseudomonas aeruginosa immunotype 1 lipopolysaccharide-specific monoclonal antibody (MAb) in a murine thigh infection model: combined effects of MAb and ceftazidime.
Topics: Animals; Antibodies, Monoclonal; Ceftazidime; Cephalosporins; Combined Modality Therapy; Disease Models, Animal; Female; Humans; Immunoglobulin G; Immunoglobulins; Lipopolysaccharides; Mice; Neutrophils; Phagocytosis; Pseudomonas aeruginosa; Pseudomonas Infections; Thigh | 2000 |
In vitro and In vivo activities of LB 10827, a new oral cephalosporin, against respiratory pathogens.
Topics: Animals; Cephalosporins; Disease Models, Animal; Female; Haemophilus influenzae; Male; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Moraxella catarrhalis; Neutropenia; Pneumonia, Pneumococcal; Rats; Rats, Sprague-Dawley; Respiratory Tract Infections; Streptococcus pneumoniae; Treatment Outcome | 2000 |
Locally delivered antibodies combined with systemic antibiotics confer synergistic protection against antibiotic-resistant burn wound infection.
Topics: Animals; Burns; Ceftazidime; Cephalosporins; Combined Modality Therapy; Cross Infection; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Drug Synergism; Female; Immunoglobulins, Intravenous; Infusions, Intravenous; Injections, Subcutaneous; Mice; Mice, Inbred Strains; Pseudomonas Infections; Survival Analysis; Wound Infection | 2000 |
In vitro and in vivo properties of Ro 63-9141, a novel broad-spectrum cephalosporin with activity against methicillin-resistant staphylococci.
Topics: Abscess; Animals; Bacterial Proteins; beta-Lactamases; Carrier Proteins; Cephalosporins; Disease Models, Animal; Enzyme Stability; Hexosyltransferases; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidyl Transferases; Sepsis; Staphylococcus aureus; Substrate Specificity | 2001 |
Efficacy of an evernimicin (SCH27899) in vitro and in an animal model of Lyme disease.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Borrelia burgdorferi Group; Ceftriaxone; Cephalosporins; Disease Models, Animal; Female; Lyme Disease; Mice; Mice, Inbred C3H; Microbial Sensitivity Tests; Treatment Outcome | 2001 |
Active immunization with a detoxified Escherichia coli J5 lipopolysaccharide group B meningococcal outer membrane protein complex vaccine protects animals from experimental sepsis.
Topics: Animals; Antibodies, Bacterial; Bacterial Outer Membrane Proteins; Ceftazidime; Cephalosporins; Cyclophosphamide; Disease Models, Animal; Disease-Free Survival; Endotoxins; Escherichia coli; Escherichia coli Vaccines; Female; Klebsiella pneumoniae; Lipopolysaccharides; Neisseria meningitidis; Neutropenia; Pseudomonas aeruginosa; Rats; Rats, Sprague-Dawley; Sepsis; Vaccines, Conjugate | 2001 |
In vivo efficacy of continuous infusion versus intermittent dosing of ceftazidime alone or in combination with amikacin relative to human kinetic profiles in a Pseudomonas aeruginosa rabbit endocarditis model.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Endocarditis, Bacterial; Female; Humans; Kinetics; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Rabbits | 2001 |
Efficacy of gatifloxacin alone and in combination with cefepime against penicillin-resistant Streptococcus pneumoniae in a rabbit meningitis model and in vitro.
Topics: Animals; Anti-Infective Agents; Cefepime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Fluoroquinolones; Gatifloxacin; Meningitis, Bacterial; Microbial Sensitivity Tests; Penicillin Resistance; Rabbits; Streptococcus pneumoniae; Treatment Outcome | 2001 |
Prediction of in-vivo efficacy by in-vitro early bactericidal activity with oral beta-lactams, in a dose-ranging immunocompetent mouse sepsis model, using strains of Streptococcus pneumoniae with decreasing susceptibilities to penicillin.
Topics: Amoxicillin; Animals; Area Under Curve; Cefpodoxime; Ceftizoxime; Cefuroxime; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Forecasting; Mice; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Pneumococcal Infections; Predictive Value of Tests; Sepsis; Streptococcus pneumoniae | 2001 |
A mouse model of Streptococcus pneumoniae meningitis mimicking several features of human disease.
Topics: Animals; Body Weight; Brain; Ceftriaxone; Cephalosporins; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Hyaluronan Receptors; Immunohistochemistry; Intercellular Adhesion Molecule-1; Leukocyte Count; Leukocytes; Macrophage Colony-Stimulating Factor; Macrophage-1 Antigen; Meningitis, Pneumococcal; Mice; Mice, Inbred C57BL; Mice, Knockout; Streptococcus pneumoniae; Survival Rate; Treatment Outcome | 2001 |
Mechanism of therapeutic effectiveness of cefixime against typhoid fever.
Topics: Animals; Cefixime; Cell Survival; Cephalosporins; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Salmonella; Salmonella Infections; Serotyping; Treatment Outcome; Tumor Cells, Cultured; Typhoid Fever | 2001 |
Lipopolyamines as a therapeutic strategy in experimental Gram-negative bacterial sepsis.
Topics: Animals; Bacteremia; Ceftazidime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Gram-Negative Bacterial Infections; Neutropenia; Rats; Sepsis; Survival Analysis | 2001 |
[In vitro and in vivo activities of panipenem against penicillin-resistant Streptococcus pneumoniae].
Topics: Ampicillin; Animals; beta-Alanine; Cefozopran; Ceftriaxone; Cephalosporins; Cilastatin; Cilastatin, Imipenem Drug Combination; Disease Models, Animal; Drug Combinations; Drug Resistance; Imipenem; Male; Meropenem; Mice; Mice, Inbred Strains; Penicillin Resistance; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Thienamycins; Vancomycin | 2001 |
A simple infection model using pre-colonized implants to reproduce rat chronic Staphylococcus aureus osteomyelitis and study antibiotic treatment.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Cefuroxime; Cephalosporins; Chronic Disease; Ciprofloxacin; Disease Models, Animal; Male; Osteomyelitis; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Tibia; Tobramycin; Vancomycin | 2001 |
Efficacy of short-course ceftriaxone therapy for Borrelia burgdorferi infection in C3H mice.
Topics: Animals; Borrelia burgdorferi; Ceftriaxone; Cephalosporins; Disease Models, Animal; Female; Lyme Disease; Mice; Mice, Inbred C3H; Treatment Outcome | 2002 |
Influence of in-vivo endotoxin liberation on anti-anaerobic antimicrobial efficacy.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Cricetinae; Digestive System; Disease Models, Animal; Endotoxins; Gram-Negative Bacteria; Liver; Mice; Mice, Inbred BALB C; Rats; Shock, Septic | 2001 |
Effects of parenterally administered ciprofloxacin in a murine model of pulmonary Pseudomonas aeruginosa infection mimicking ventilator-associated pneumonia.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Cefozopran; Cephalosporins; Cilastatin; Ciprofloxacin; Disease Models, Animal; Imipenem; Infusions, Parenteral; Male; Mice; Pneumonia, Bacterial; Protease Inhibitors; Pseudomonas aeruginosa; Pseudomonas Infections; Respiration, Artificial; Thienamycins | 2001 |
Efficacy of ceftriaxone and gentamicin given once a day by using human-like pharmacokinetics in treatment of experimental staphylococcal endocarditis.
Topics: Animals; Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Endocarditis, Bacterial; Gentamicins; Microbial Sensitivity Tests; Rabbits; Staphylococcus aureus; Treatment Outcome | 2002 |
Cefepime is efficacious against penicillin- and quinolone-resistant pneumococci in experimental meningitis.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Cefepime; Cephalosporins; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Penicillin Resistance; Rabbits; Streptococcus pneumoniae | 2002 |
Inhibition of staphylococcal wound infection and potentiation of antibiotic prophylaxis by a recombinant fragment of the fibronectin-binding protein of Staphylococcus aureus.
Topics: Adhesins, Bacterial; Animals; Antibiotic Prophylaxis; Bacterial Proteins; Carrier Proteins; Cefazolin; Cells, Cultured; Cephalosporins; Disease Models, Animal; Drug Synergism; Endothelium, Vascular; Female; Guinea Pigs; Humans; Male; Recombinant Proteins; Staphylococcal Infections; Staphylococcus aureus; Umbilical Veins; Wound Infection | 2002 |
Pneumococcal meningitis-therapeutic studies in mice.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Cerebellum; Cerebral Cortex; Chloramphenicol; Chlortetracycline; Demeclocycline; Disease Models, Animal; Erythromycin; Lincomycin; Male; Meningitis, Pneumococcal; Mice; Penicillins; Rolitetracycline; Streptococcus pneumoniae; Tetracycline; Virulence | 1975 |
Factors influencing the penetration of antimicrobial agents into the cerebrospinal fluid of experimental animals.
Topics: Animals; Cephalosporins; Disease Models, Animal; Meningitis; Penicillins; Probenecid; Protein Binding; Rabbits | 1978 |
Cefamandole and ampicillin therapy in experimental Haemophilus influenzae meningitis.
Topics: Ampicillin; Animals; Blood; Cephalosporins; Cerebrospinal Fluid; Disease Models, Animal; Haemophilus influenzae; Injections, Intramuscular; Injections, Intravenous; Meningitis, Haemophilus; Rabbits | 1977 |
Therapy for experimental intraabdominal sepsis: comparison of four cephalosporins with clindamycin plus gentamicin.
Topics: Abdomen; Abscess; Animals; Bacteroides fragilis; Cephalosporins; Clindamycin; Disease Models, Animal; Drug Therapy, Combination; Escherichia coli; Fusobacterium; Gentamicins; Male; Microbial Sensitivity Tests; Rats; Streptococcus | 1977 |
[Animal studies on antibacterial activity of 10 cephalosporins (author's transl)].
Topics: Animals; Cephalosporins; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Estradiol; Female; Injections, Intramuscular; Pyelonephritis; Rats | 1978 |
Comparative evaluation of cephacetrile in experimentally induced bovine mastitis.
Topics: Animals; Cattle; Cephacetrile; Cephalosporins; Disease Models, Animal; Female; Mastitis, Bovine | 1979 |
Nephrotoxicity of newer cephalosporins and aminoglycosides alone and in combination in a rat model.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Cephalosporins; Disease Models, Animal; Drug Interactions; Kidney Cortex; Kidney Diseases; Male; Rats; Rats, Inbred F344; Time Factors | 1978 |
Exudate levels and bactericidal activity of cefazolin in a new local infection system using rat granuloma pouches.
Topics: Animals; Bacterial Infections; Cefazolin; Cephalosporins; Cephalothin; Disease Models, Animal; Drug Evaluation, Preclinical; Granuloma; Rats | 1977 |
Antibiotic penetrance of ascitic fluid in dogs.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Ascites; Ascitic Fluid; Cephalosporins; Clindamycin; Disease Models, Animal; Dogs; Half-Life; Metronidazole; Time Factors | 1976 |
Combined therapy of a cephalosporin, Shiomarin and a new potent protease inhibitor, E3123 in rat taurocholate-induced pancreatitis.
Topics: Acute Disease; Animals; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Guanidines; Male; Pancreatitis; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Taurocholic Acid | 1992 |
Enhancing effects of fluorescein on beta-lactam rash. II: Enhancing effects of fluorescein on generalized rash induced by beta-lactam antibiotics in guinea pigs.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Disease Models, Animal; Drug Eruptions; Drug Interactions; Fluoresceins; Guinea Pigs; Male | 1992 |
Development of resistance during ceftazidime and cefepime therapy in a murine peritonitis model.
Topics: Animals; Cefepime; Ceftazidime; Cephalosporins; Citrobacter freundii; Disease Models, Animal; Drug Resistance, Microbial; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Peritonitis; Pseudomonas aeruginosa; Pseudomonas Infections; Serratia Infections; Serratia marcescens; Virulence | 1992 |
[Transferability of cefpirome to cerebrospinal fluid of rabbits with meningitis caused by Staphylococcus aureus].
Topics: Animals; Cefpirome; Cephalosporins; Disease Models, Animal; Injections, Intravenous; Meningitis; Rabbits; Staphylococcal Infections | 1991 |
In vivo efficacy of cefcanel daloxate in comparison with cefaclor.
Topics: Absorption; Animals; Bacterial Infections; Cefaclor; Cephalosporins; Disease Models, Animal; Escherichia coli Infections; Female; Klebsiella Infections; Klebsiella pneumoniae; Mice; Prodrugs; Staphylococcal Infections | 1990 |
Antibacterial activity of four cephalosporins in an experimental infection in relation to in vitro effect and pharmacokinetics.
Topics: Agranulocytosis; Animals; Cefamandole; Ceftazidime; Ceftriaxone; Cefuroxime; Cephalosporins; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Klebsiella Infections; Klebsiella pneumoniae; Mice; Protein Binding; Specific Pathogen-Free Organisms | 1990 |
Cefepime for treatment of experimental chronic osteomyelitis due to Staphylococcus aureus.
Topics: Animals; Cefepime; Cephalosporins; Chronic Disease; Disease Models, Animal; Osteomyelitis; Rabbits; Staphylococcal Infections | 1990 |
Characterization of a soft-tissue infection model in the horse and its response to intravenous cephapirin administration.
Topics: Animals; Cephalosporins; Cephapirin; Diffusion Chambers, Culture; Disease Models, Animal; Erythrocyte Count; Female; Horse Diseases; Horses; Injections, Intravenous; Leukocyte Count; Male; Neutrophils; Skin Diseases, Infectious; Streptococcal Infections | 1989 |
Duration of antibiotic prophylaxis. An experimental study.
Topics: Animals; Cephalosporins; Disease Models, Animal; Drug Administration Schedule; Escherichia coli Infections; Female; Half-Life; Mice; Mice, Inbred Strains; Premedication; Staphylococcal Infections; Surgical Wound Infection | 1986 |
The hematologic effects of cefonicid and cefazedone in the dog: a potential model of cephalosporin hematotoxicity in man.
Topics: Anemia; Animals; Cefamandole; Cefazolin; Cefonicid; Cephalosporins; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Female; Hematologic Diseases; Male; Neutropenia; Thrombocytopenia | 1987 |
The hematopathology of cefonicid- and cefazedone-induced blood dyscrasias in the dog.
Topics: Animals; Bone Marrow; Cefamandole; Cefazolin; Cefonicid; Cephalosporins; Disease Models, Animal; Dogs; Hematopoiesis; Liver; Neutrophils; Paraproteinemias | 1987 |
A rat model of bacterial keratitis. Effect of antibiotics and corticosteroid.
Topics: Animals; Bacterial Infections; Cephalosporins; Cephradine; Disease Models, Animal; Drug Therapy, Combination; Gentamicins; Keratitis; Leukocyte Count; Penicillin G; Prednisolone; Pseudomonas Infections; Rats; Staphylococcal Infections; Streptococcal Infections | 1985 |
Role of cephalosporins in the treatment of bacterial meningitis in adults. Overview with special emphasis on ceftazidime.
Topics: Adult; Animals; Bacterial Infections; Cefoperazone; Cefotaxime; Ceftazidime; Ceftriaxone; Cephalosporins; Disease Models, Animal; Humans; Meningitis | 1985 |
Cephaloglycin and its biologically active metabolite desacetylcephaloglycin.
Topics: Administration, Oral; Animals; Bacillus subtilis; Bacteria; Biological Assay; Cephalosporins; Chromatography, Paper; Disease Models, Animal; Drug Resistance, Microbial; Drug Stability; Human Experimentation; Humans; Male; Mice; Microbial Sensitivity Tests; Sarcina; Species Specificity; Temperature; Urinary Tract Infections | 1971 |
Relative nephrotoxicity of cephalosporin antibiotics in an animal model.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cephalexin; Cephaloridine; Cephalosporins; Cephalothin; Disease Models, Animal; Furosemide; Glycerol; Injections, Subcutaneous; Male; Rats; Rats, Inbred Strains | 1972 |
[Comparison of the effects of gentamicin and other chemotherapeutic agents in experimental urinary tract infections].
Topics: Animals; Anti-Infective Agents; Cephalosporins; Colistin; Cystitis; Disease Models, Animal; Gentamicins; Nalidixic Acid; Pyelonephritis; Rats; Sulfadiazine; Urinary Tract Infections | 1970 |