Page last updated: 2024-08-24

cephalosporin c and Critical Illness

cephalosporin c has been researched along with Critical Illness in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	8 (10.81)	18.2507
2000's	15 (20.27)	29.6817
2010's	29 (39.19)	24.3611
2020's	22 (29.73)	2.80

Authors

Authors	Studies
Andrea, T; Bremmer, DN; Cain, AR; Finoli, LM; Guarascio, A; Ogbebor, O; Shively, NR	1
Butler, D; Katsube, T; Tan, X; Wajima, T; Wenzler, E	1
Artés, JF; de Pedro, MB; Galleymore, PR; Martín-Cerezuela, M; Padrós Olmedo, MŸ; Piqueres, SP	1
Alshaer, MH; Barreto, EF; Bruzzone, M; Bumanglag, AV; Burke, SN; Chang, J; Downes, KJ; Lesnicki, E; Pais, GM; Panchal, V; Scheetz, MH; Stitt, G	1
Amadesi, S; Ambretti, S; Gaibani, P; Lazzarotto, T	1
Bleibtreu, A; Chommeloux, J; Combes, A; Coppens, A; Hekimian, G; Junot, H; LeFevre, L; Luyt, CE; Pineton de Chambrun, M; Robert, J; Schmidt, M; Zahr, N	1
Berry, AV; Conelius, A; Gluck, JA; Kuti, JL; Nicolau, DP	1
Casey, JD; Qian, ET; Rice, TW; Semler, MW; Stollings, JL; Wang, L	1
Möhlmann, JE; Sikma, MA; Uijtendaal, EV; van Luin, M; Zahr, N	1
Brüggemann, RJ; de Wildt, SN; Dia, N; Hartman, SJF; Orriëns, L; Schreuder, MF	1
Cotta, MO; Dulhunty, JM; Eriksson, L; Harris, P; Malacova, E; Milinovich, GJ; Vickers, ML	1
Lassig-Smith, M; Lipman, J; Pandey, S; Parker, SL; Roberts, JA; Sime, FB; Starr, T; Stuart, J; Wallis, SC	1
Aguilar, G; Blasco, ML; Calabuig, M; Carbonell, N; Colomina, J; Ezquer, C; Ferreres, J; Ferriols, R; Huerta, R; Juan, M	1
Bardonneau, G; Biais, M; Carrié, C; Gruson, D; Ouattara, A; Pereira, B; Petit, L	1
Barreto Gutierrez, L; De Bels, D; Gallerani, A; Honore, PM; Kaefer, K; Mugisha, A; Redant, S	1
Aso, S; Fushimi, K; Goto, H; Kaita, Y; Kojiro, M; Matsui, H; Nakajima, M; Yamaguchi, Y; Yasunaga, H	1
Adedoyin, A; Caro, L; De Waele, JJ; Gadzicki, E; Kuti, JL; Larson, KB; Nicolau, DP; Rhee, EG; Yu, B; Zeng, Z	1
Concordet, D; Delmas, C; Gandia, P; Georges, B; Jourdan, G; Mané, C; Marcheix, B; Porterie, J; Ruiz, S; Verwaerde, P	1
De Ponti, F; Gatti, M; Giannella, M; Raschi, E; Viale, P	1
Asensio-Martín, MJ; Balandin, B; Ballesteros, D; Chicot, M; Fernández-Simón, I; Iranzo, R; López-Vergara, L; Martínez-Sagasti, F; Pérez-Pedrero, MJ; Pintado, V; Rodríguez-Serrano, D; Royuela, A; Ruiz de Luna, R; Sancho-González, M; Silva, A; Soriano-Cuesta, C	1
Ali, F; Gopalakrishnan, M; Guo, D; Heavner, M; Jean, W; Kalaria, S; Li, M; Medlin, C; Shu, Y; Williford, S; Yeung, SYA	1
André, C; Bennis, Y; Bodeau, S; Dupont, H; Kontar, L; Lemaire-Hurtel, AS; Mary, A; Mernissi, T; Zahr, N	1
Bardonneau, G; Biais, M; Carrie, C; Oddos, C; Petit, L	1
Brown, M; Gamage, HKAH; Ginn, AN; Holmes, A; Iredell, JR; Kabir, M; Nayyar, V; Partridge, SR; Paulsen, IT; Roychoudhry, B; Seppelt, I; Tetu, SG; Thomas, L; Venturini, C	1
Collings, H; Dillon, R; Enstone, A; Palmer, T; Puzniak, L	1
Fratoni, AJ; Kuti, JL; Nicolau, DP	1
Gatti, M; Pea, F	1
Mueller, BA; Shaw, AR	1
Borgia, G; Cascella, M; Corcione, S; Cuomo, A; De Rosa, FG; Gentile, I; Maraolo, AE; Nappa, S	1
Gomez-Simmonds, A; McConville, TH; Sullivan, SB; Uhlemann, AC; Whittier, S	1
Chopra, A; Cies, JJ; Enache, A; Moore, WS	1
Bassetti, M; Cojutti, PG; De Stefanis, P; Fregonese, C; Lucchese, F; Merelli, M; Pea, F	1
Castellanos, Á; Frasquet, J; Gordon, M; Martín, M; Ramirez, P; Ruiz, J; Sánchez, MÁ; Villarreal, E	1
Aguilar, G; Alós, M; Carbonell, JA; Ezquer, C; Ferriols, R; Martínez-Castro, S; Navarro, D; Pastor, E	1
Bodmann, KF	1
Azanza Perea, JR; Sádaba Díaz de Rada, B	1
Cillóniz, C; Dominedò, C; Garcia-Vidal, C; Torres, A	1
Biamonte, E; Bruni, A; Garofalo, E; Liberto, MC; Lionello, R; Longhini, F; Marascio, N; Matera, G; Mazzitelli, M; Navalesi, P; Quirino, A; Scaglione, V; Serapide, F; Torti, C; Trecarichi, EM	1
Boucher, BA; Croce, MA; Fabian, TC; Ponnapula, S; Swanson, JM; Wells, DL; Wood, GC	1
Boucher, BA; Croce, MA; Fabian, TC; Monteen, MR; Ponnapula, S; Swanson, JM; Wood, GC	1
Gonzales, JP; Heil, EL; Mehrotra, S; Nicolau, DP; Oliver, WD; Robinett, K; Saleeb, P	1
Hammond, DA; Lusardi, K; Meena, NK; Painter, JT; Smith, MN	1
Berth, M; Colin, P; De Beenhouwer, H; De Neve, N; Jonckheere, S; Van Bocxlaer, J; Vermeulen, A	1
Mouton, JW; Pea, F; Torres, A	1
Ghazi, IM; Kuti, JL; Nicolau, DP; Quintiliani, R; Shore, E	1
Danziger, LH; Glowacki, RC; Horn, KS; Rodvold, KA	1
Alquezar, A; Castro, P; Codina, C; Delgado, E; Marco, F; Martí, S; Martínez, JA; Mensa, J; Nicolás, JM; Soriano, A; Torres, A; Trilla, A; Vila, J	1
Ariano, RE; Crandon, JL; Kim, A; Kuti, JL; Nicasio, AM; Nicolau, DP; Zelenitsky, SA	1
Bain, BJ; Innes, A	1
Gonçalves-Pereira, J; Póvoa, P	1
Aziz, NA; Chong, CP; Lim, PP	1
De Waele, JJ; Lipman, J; Paterson, DL; Roberts, JA; Udy, AA	1
Delattre, IK; Jacobs, F; Jacqmin, P; Laterre, PF; Musuamba, FT; Taccone, FS; Verbeeck, RK; Wallemacq, P	1
Arzuaga, A; Gascón, AR; Isla, A; Maynar, J; Pedraz, JL; Toral, D	1
Archambaud, M; Chabanon, G; Conil, JM; Cougot, P; Decun, JF; Georges, B; Houin, G; Saivin, S; Seguin, T; Virenque, C	1
de Roux, A; Lode, H; Schmidt-Ioanas, M	1
Baraniak, A; Bossaert, L; Demey, HE; Gniadkowski, M; Goethaert, K; Goossens, H; Ieven, M; Jansens, H; Jorens, PG; Lammens, C; Van Herck, K; Van Looveren, M	1
Lipman, J; Roberts, JA; Webb, SA	1
Kirkpatrick, CMJ; Lipman, J; Roos, JF	1
Healy, B; Pegler, S	1
Benko, AS; Cappelletty, DM; Kruse, JA; Rybak, MJ	1
Gin, T; Gomersall, CD; Joynt, GM; Lipman, J; Oh, TE; Young, RJ	1
Sieger, B	1
Cambronero Galache, JA; Cerdá Cerdá, E; Gómez Aguinaga, MA; López Diaz, J; Núnez Reiz, A; Onoro Canaveral, JJ; Rogero Marín, S; Rubio Blasco, J; Sacristán del Castillo, JA; Sánchez García, M	1
Davies, JG; Kingswood, C; Olliff, CJ; Phillips, GJ; Street, M	1
Hamaguchi, M; Kikuta, K; Kitaura, M; Kukita, I; Okamoto, K; Sato, T	1
Cordingly, JJ; Gómez, CM; Palazzo, MG	1
Lipman, J; Rickard, C; Wallis, SC	1
Boucher, BA; Croce, MA; Fabian, TC; Hanes, SD; Herring, V; Pritchard, E; Wood, GC	1
Gin, T; Gomersall, CD; Joynt, GM; Lipman, J; Wong, EL; Young, RJ	1
Fraenkel, D; Lipman, J; Rickard, CM; Wallis, SC	1
Alvarez-Lerma, F; Cerda, E; Olaechea, P; Palomar, M; Sierra, R	1
Abraham, E; Fish, DN; Malone, RS; Teitelbaum, I	1
Mittermeyer, C; Ratheiser, K; Schenk, P; Thalhammer, F; Thalhammer-Scherrer, R; Traunmüller, F	1

Reviews

16 review(s) available for cephalosporin c and Critical Illness

Article	Year
Clinical Pharmacokinetics and Pharmacodynamics of Cefepime. Clinical pharmacokinetics, 2022, Volume: 61, Issue:7 Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Critical Illness; Humans; Microbial Sensitivity Tests	2022
Pharmacokinetics and Target Attainment of Antibiotics in Critically Ill Children: A Systematic Review of Current Literature. Clinical pharmacokinetics, 2020, Volume: 59, Issue:2 Topics: Acute Kidney Injury; Adolescent; Aminoglycosides; Anti-Bacterial Agents; Area Under Curve; Carbapenems; Cephalosporins; Child; Child, Preschool; Critical Illness; Drug Monitoring; Female; Half-Life; Humans; Infant; Infusions, Intravenous; Male; Penicillins; Vancomycin; Young Adult	2020
Modifiable risk factors for multidrug-resistant Gram-negative infection in critically ill burn patients: a systematic review and meta-analysis. ANZ journal of surgery, 2019, Volume: 89, Issue:10 Topics: Aminoglycosides; Anti-Bacterial Agents; Burns; Carbapenems; Cephalosporins; Critical Illness; Cross Infection; Drug Resistance, Multiple; Gram-Negative Bacterial Infections; Humans; Hydrotherapy; Intensive Care Units; Penicillins; Respiration, Artificial; Risk Factors; Urinary Catheters; Vascular Access Devices	2019
Real-world use of ceftolozane/tazobactam: a systematic literature review. Antimicrobial resistance and infection control, 2021, 04-08, Volume: 10, Issue:1 Topics: Cephalosporins; Comorbidity; Critical Illness; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacterial Infections; Humans; Intraabdominal Infections; Pseudomonas Infections; Respiratory Tract Infections; Tazobactam; Urinary Tract Infections	2021
Continuous versus intermittent infusion of antibiotics in Gram-negative multidrug-resistant infections. Current opinion in infectious diseases, 2021, 12-01, Volume: 34, Issue:6 Topics: Anti-Bacterial Agents; Cephalosporins; Critical Illness; Drug Combinations; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections	2021
Antibiotic Dosing in Continuous Renal Replacement Therapy. Advances in chronic kidney disease, 2017, Volume: 24, Issue:4 Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Computer Simulation; Critical Illness; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Renal Replacement Therapy; Sepsis; Tazobactam; Thienamycins	2017
Management of multidrug-resistant Pseudomonas aeruginosa in the intensive care unit: state of the art. Expert review of anti-infective therapy, 2017, Volume: 15, Issue:9 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Ceftazidime; Cephalosporins; Critical Illness; Disease Management; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Intensive Care Units; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Factors; Tazobactam; Treatment Outcome	2017
[The 2018 Update of the Recommendations of the Paul-Ehrlich-Society for Chemotherapy on the Initial Parenteral Therapy of Bacterial Diseases in Adults - What's relevant for Intensive Care?] Deutsche medizinische Wochenschrift (1946), 2019, Volume: 144, Issue:11 Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Critical Care; Critical Illness; Humans; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Pneumonia, Bacterial; Practice Guidelines as Topic; Sepsis; Staphylococcal Infections	2019
Ceftobiprole: pharmacokinetics and PK/PD profile. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2019, Volume: 32 Suppl 3 Topics: Age Factors; Anti-Bacterial Agents; Area Under Curve; Cephalosporins; Creatinine; Critical Illness; Extracellular Matrix; Half-Life; Humans; Infusions, Intravenous; Kidney; Monte Carlo Method; Obesity; Prodrugs; Renal Insufficiency; Renal Replacement Therapy	2019
Ceftobiprole for the treatment of pneumonia. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2019, Volume: 32 Suppl 3 Topics: Anti-Bacterial Agents; Cephalosporins; Clinical Trials as Topic; Community-Acquired Infections; Critical Illness; Cross Infection; Drug Administration Schedule; Humans; Pneumonia, Bacterial; Renal Insufficiency	2019
Pharmacokinetics and Dosing of Ceftobiprole Medocaril for the Treatment of Hospital- and Community-Acquired Pneumonia in Different Patient Populations. Clinical pharmacokinetics, 2016, Volume: 55, Issue:12 Topics: Anti-Bacterial Agents; Area Under Curve; Cephalosporins; Community-Acquired Infections; Critical Illness; Cross Infection; Dose-Response Relationship, Drug; Drug Dosage Calculations; Half-Life; Humans; Infusions, Intravenous; Metabolic Clearance Rate; Microbial Sensitivity Tests; Monte Carlo Method; Pediatrics; Pneumonia; Renal Insufficiency	2016
Pharmacokinetic drug evaluation of ceftobiprole for the treatment of MRSA. Expert opinion on drug metabolism & toxicology, 2017, Volume: 13, Issue:4 Topics: Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Critical Illness; Cross Infection; Humans; Methicillin-Resistant Staphylococcus aureus; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Staphylococcal Infections	2017
Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams. Critical care (London, England), 2011, Volume: 15, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Cefpirome; Ceftazidime; Cephalosporins; Critical Illness; Humans; Imipenem; Infections; Meropenem; Piperacillin; Thienamycins	2011
New antibiotics for the treatment of severe staphylococcal infection in the critically ill patient. Current opinion in critical care, 2005, Volume: 11, Issue:5 Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Cephalosporins; Clinical Trials as Topic; Critical Illness; Daptomycin; Drug Resistance, Multiple, Bacterial; Glycopeptides; Humans; Linezolid; Lipoglycopeptides; Methicillin Resistance; Minocycline; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Tigecycline; Virginiamycin	2005
Cefepime versus ceftazidime: considerations for empirical use in critically ill patients. International journal of antimicrobial agents, 2007, Volume: 29, Issue:2 Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Community-Acquired Infections; Critical Illness; Cross Infection; Drug Resistance; Economics, Pharmaceutical; Humans; Pneumonia, Bacterial	2007
In patients allergic to penicillin, consider second and third generation cephalosporins for life threatening infections. BMJ (Clinical research ed.), 2007, Nov-10, Volume: 335, Issue:7627 Topics: Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Critical Illness; Drug Hypersensitivity; Humans; Penicillins	2007

Trials

12 trial(s) available for cephalosporin c and Critical Illness

Article	Year
Lung penetration, bronchopulmonary pharmacokinetic/pharmacodynamic profile and safety of 3 g of ceftolozane/tazobactam administered to ventilated, critically ill patients with pneumonia. The Journal of antimicrobial chemotherapy, 2020, 06-01, Volume: 75, Issue:6 Topics: Anti-Bacterial Agents; Cephalosporins; Critical Illness; Humans; Lung; Pneumonia; Tazobactam	2020
A model-based analysis of the predictive performance of different renal function markers for cefepime clearance in the ICU. The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:9 Topics: Aged; Anti-Bacterial Agents; Biomarkers; Cefepime; Cephalosporins; Critical Illness; Female; Humans; Intensive Care Units; Kidney; Kidney Function Tests; Male; Metabolic Clearance Rate; Plasma; Urine	2016
Population pharmacokinetics of high-dose, prolonged-infusion cefepime in adult critically ill patients with ventilator-associated pneumonia. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Critical Illness; Humans; Metabolic Clearance Rate; Microbial Sensitivity Tests; Middle Aged; Pneumonia, Ventilator-Associated	2009
Population pharmacokinetics of four β-lactams in critically ill septic patients comedicated with amikacin. Clinical biochemistry, 2012, Volume: 45, Issue:10-11 Topics: Adult; Aged; Aged, 80 and over; Algorithms; Amikacin; Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Critical Illness; Drug Monitoring; Female; Humans; Male; Meropenem; Metabolic Clearance Rate; Middle Aged; Models, Biological; Piperacillin; Sepsis; Thienamycins; Tissue Distribution; Treatment Outcome	2012
Cefepime in critically ill patients: continuous infusion vs. an intermittent dosing regimen. International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:8 Topics: Adult; Aged; Amikacin; Anti-Bacterial Agents; Area Under Curve; Cefepime; Cephalosporins; Critical Illness; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Time Factors; Treatment Outcome	2005
High-dose cefepime as an alternative treatment for infections caused by TEM-24 ESBL-producing Enterobacter aerogenes in severely-ill patients. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2006, Volume: 12, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Critical Illness; Cross Infection; Drug Therapy, Combination; Enterobacter aerogenes; Enterobacteriaceae Infections; Female; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Treatment Outcome	2006
Continuous infusion versus intermittent administration of ceftazidime in critically ill patients with suspected gram-negative infections. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:3 Topics: Ceftazidime; Cephalosporins; Creatinine; Critical Illness; Cross-Over Studies; Female; Gram-Positive Bacterial Infections; Half-Life; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Serum Bactericidal Test	1996
Effectiveness and cost of selective decontamination of the digestive tract in critically ill intubated patients. A randomized, double-blind, placebo-controlled, multicenter trial. American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:3 Topics: Bacteria; Bacterial Infections; Cause of Death; Ceftriaxone; Cephalosporins; Colony Count, Microbial; Confidence Intervals; Critical Care; Critical Illness; Digestive System; Double-Blind Method; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Health Care Costs; Humans; Incidence; Intubation, Intratracheal; Length of Stay; Male; Middle Aged; Oropharynx; Placebos; Pneumonia, Bacterial; Respiration, Artificial; Survival Rate	1998
Low plasma cefepime levels in critically ill septic patients: pharmacokinetic modeling indicates improved troughs with revised dosing. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:10 Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Computer Simulation; Critical Illness; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pseudomonas aeruginosa	1999
Intermittent and continuous ceftazidime infusion for critically ill trauma patients. American journal of surgery, 2000, Volume: 179, Issue:6 Topics: Adolescent; Adult; Aged; Ceftazidime; Cephalosporins; Chi-Square Distribution; Critical Illness; Cross Infection; Drug Administration Schedule; Female; Follow-Up Studies; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Pneumonia, Bacterial; Probability; Treatment Outcome; Wounds and Injuries	2000
The pharmacokinetics of once-daily dosing of ceftriaxone in critically ill patients. The Journal of antimicrobial chemotherapy, 2001, Volume: 47, Issue:4 Topics: Adolescent; Adult; Aged; Ceftriaxone; Cephalosporins; Critical Illness; Female; Half-Life; Humans; Kidney; Male; Middle Aged; Pneumonia; Renal Insufficiency; Sepsis	2001
Pharmacokinetics of cefepime during continuous renal replacement therapy in critically ill patients. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:11 Topics: Adult; Aged; Area Under Curve; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Critical Illness; Female; Hemofiltration; Humans; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Spectrophotometry, Ultraviolet	2001

Other Studies

46 other study(ies) available for cephalosporin c and Critical Illness

Article	Year
Ceftaroline Pharmacokinetics in a Critically Ill Adult Receiving Continuous Venovenous Hemodiafiltration. The Annals of pharmacotherapy, 2022, Volume: 56, Issue:8 Topics: Acute Kidney Injury; Adult; Ceftaroline; Cephalosporins; Continuous Renal Replacement Therapy; Critical Illness; Humans	2022
Pharmacokinetics, Pharmacodynamics, and Dose Optimization of Cefiderocol during Continuous Renal Replacement Therapy. Clinical pharmacokinetics, 2022, Volume: 61, Issue:4 Topics: Anti-Bacterial Agents; Bayes Theorem; Cefiderocol; Cephalosporins; Clinical Trials, Phase III as Topic; Continuous Renal Replacement Therapy; Critical Illness; Humans; Microbial Sensitivity Tests; Renal Replacement Therapy	2022
Ceftaroline versus standard therapy for pneumococcal meningitis in critically ill patients. Medicina intensiva, 2022, Volume: 46, Issue:6 Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Critical Illness; Humans; Meningitis, Pneumococcal	2022
Genome characterization of a Klebsiella pneumoniae co-producing OXA-181 and KPC-121 resistant to ceftazidime/avibactam, meropenem/vaborbactam, imipenem/relebactam and cefiderocol isolated from a critically ill patient. Journal of global antimicrobial resistance, 2022, Volume: 30 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Boronic Acids; Cefiderocol; Ceftazidime; Cephalosporins; Critical Illness; Humans; Imipenem; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests	2022
Pharmacokinetics/pharmacodynamics of ceftobiprole in patients on extracorporeal membrane oxygenation. International journal of antimicrobial agents, 2023, Volume: 61, Issue:4 Topics: Cephalosporins; Cohort Studies; Critical Illness; Extracorporeal Membrane Oxygenation; Humans; Retrospective Studies	2023
Cefiderocol is Not Sequestered in an Ex Vivo Extracorporeal Membrane Oxygenation (ECMO) Circuit. European journal of drug metabolism and pharmacokinetics, 2023, Volume: 48, Issue:4 Topics: Adult; Anti-Bacterial Agents; Cefiderocol; Cephalosporins; Critical Illness; Extracorporeal Membrane Oxygenation; Humans	2023
Piperacillin-Tazobactam Versus Anti-Pseudomonal Cephalosporins and Renal and Neurologic Outcomes in Critically Ill Adults: A Secondary Analysis of the SMART Trial. Journal of intensive care medicine, 2023, Volume: 38, Issue:12 Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Cephalosporins; Clinical Trials as Topic; Coma; Critical Illness; Delirium; Drug Therapy, Combination; Humans; Piperacillin, Tazobactam Drug Combination	2023
Continuous infusion of cefiderocol in a critically ill patient with continuous venovenous haemofiltration. British journal of clinical pharmacology, 2023, Volume: 89, Issue:12 Topics: Adult; Anti-Bacterial Agents; Cefiderocol; Cephalosporins; Continuous Renal Replacement Therapy; Critical Illness; Female; Humans	2023
A Population Pharmacokinetic Model-Guided Evaluation of Ceftolozane-Tazobactam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemodiafiltration. Antimicrobial agents and chemotherapy, 2019, 12-20, Volume: 64, Issue:1 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cephalosporins; Confidence Intervals; Continuous Renal Replacement Therapy; Critical Illness; Hemodiafiltration; Humans; Microbial Sensitivity Tests; Prospective Studies; Pseudomonas aeruginosa; Tazobactam	2019
Ceftolozane Pharmacokinetics in a Septic Critically Ill Patient under Different Extracorporeal Replacement Therapies. Antimicrobial agents and chemotherapy, 2019, 12-20, Volume: 64, Issue:1 Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Critical Illness; Female; Hemodiafiltration; Humans; Microbial Sensitivity Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pseudomonas aeruginosa; Pseudomonas Infections	2019
Piperacillin-tazobactam should be preferred to third-generation cephalosporins to treat wild-type inducible AmpC-producing Enterobacterales in critically ill patients with hospital or ventilator-acquired pneumonia. Journal of critical care, 2020, Volume: 56 Topics: Aged; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cephalosporins; Critical Illness; Cross Infection; Enterobacter; Family Characteristics; Female; Hospitals; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Penicillanic Acid; Piperacillin, Tazobactam Drug Combination; Pneumonia, Ventilator-Associated; Retrospective Studies; Ventilators, Mechanical	2020
Optimizing ceftolozane-tazobactam dosage during continuous renal replacement therapy: additional insights. Critical care (London, England), 2019, 12-12, Volume: 23, Issue:1 Topics: Cephalosporins; Continuous Renal Replacement Therapy; Critical Illness; Humans; Tazobactam	2019
Effect of high-dose vitamin C therapy on severe burn patients: a nationwide cohort study. Critical care (London, England), 2019, 12-12, Volume: 23, Issue:1 Topics: Adult; Ascorbic Acid; Burns; Cephalosporins; Cohort Studies; Continuous Renal Replacement Therapy; Critical Illness; Humans; Tazobactam	2019
Influence of extracorporeal membrane oxygenation on the pharmacokinetics of ceftolozane/tazobactam: an ex vivo and in vivo study. Journal of translational medicine, 2020, 05-27, Volume: 18, Issue:1 Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Critical Illness; Extracorporeal Membrane Oxygenation; Humans; Swine; Tazobactam	2020
Ceftolozane/tazobactam exposure in critically ill patients undergoing continuous renal replacement therapy: a PK/PD approach to tailor dosing. The Journal of antimicrobial chemotherapy, 2021, 01-01, Volume: 76, Issue:1 Topics: Anti-Bacterial Agents; Cephalosporins; Continuous Renal Replacement Therapy; Critical Illness; Humans; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Pseudomonas aeruginosa; Renal Replacement Therapy; Tazobactam	2021
Multicenter study of ceftolozane/tazobactam for treatment of Pseudomonas aeruginosa infections in critically ill patients. International journal of antimicrobial agents, 2021, Volume: 57, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cephalosporins; Critical Illness; Cross Infection; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Female; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Spain; Tazobactam; Treatment Outcome	2021
Optimizing ceftaroline dosing in critically ill patients undergoing continuous renal replacement therapy. Pharmacotherapy, 2021, Volume: 41, Issue:2 Topics: Adult; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Continuous Renal Replacement Therapy; Critical Illness; Dose-Response Relationship, Drug; Humans; Intensive Care Units	2021
An HPLC assay for the therapeutic drug monitoring of cefiderocol in critically ill patients. The Journal of antimicrobial chemotherapy, 2021, 05-12, Volume: 76, Issue:6 Topics: Anti-Bacterial Agents; Cefiderocol; Cephalosporins; Chromatography, High Pressure Liquid; Critical Illness; Drug Monitoring; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests	2021
Are third-generation cephalosporins still an option for empirical antibiotic therapy in critically ill trauma patients with early ventilator or hospital-acquired pneumonia? Anaesthesia, critical care & pain medicine, 2021, Volume: 40, Issue:2 Topics: Anti-Bacterial Agents; Cephalosporins; Critical Illness; Cross Infection; Hospitals; Humans; Pneumonia; Ventilators, Mechanical	2021
Third generation cephalosporins and piperacillin/tazobactam have distinct impacts on the microbiota of critically ill patients. Scientific reports, 2021, 03-31, Volume: 11, Issue:1 Topics: Adult; Animals; Antimicrobial Stewardship; Cephalosporins; Critical Illness; Enterobacteriaceae; Female; Humans; Male; Microbiota; Piperacillin, Tazobactam Drug Combination; RNA, Bacterial; RNA, Ribosomal, 16S	2021
Optimised cefiderocol exposures in a successfully treated critically ill patient with polymicrobial Stenotrophomonas maltophilia bacteraemia and pneumonia receiving continuous venovenous haemodiafiltration. International journal of antimicrobial agents, 2021, Volume: 58, Issue:3 Topics: Anti-Bacterial Agents; Cefiderocol; Cephalosporins; Coinfection; Continuous Renal Replacement Therapy; Critical Illness; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacterial Infections; Humans; Male; Middle Aged; Pneumonia; Stenotrophomonas maltophilia	2021
Carbapenem-resistant Enterobacteriaceae colonization (CRE) and subsequent risk of infection and 90-day mortality in critically ill patients, an observational study. PloS one, 2017, Volume: 12, Issue:10 Topics: Aged; Aged, 80 and over; Carbapenems; Cephalosporins; Cohort Studies; Critical Illness; Cross Infection; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Intensive Care Units; Male; Rectum	2017
Ceftaroline for Suspected or Confirmed Invasive Methicillin-Resistant Staphylococcus aureus: A Pharmacokinetic Case Series. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2018, Volume: 19, Issue:6 Topics: Adolescent; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Child; Child, Preschool; Critical Illness; Female; Humans; Infant; Intensive Care Units, Pediatric; Male; Methicillin-Resistant Staphylococcus aureus; Prospective Studies; Retrospective Studies; Staphylococcal Infections; Treatment Outcome	2018
Disposition of ceftobiprole during continuous venous-venous hemodiafiltration (CVVHDF) in a single critically ill patient. European journal of clinical pharmacology, 2018, Volume: 74, Issue:12 Topics: Anti-Bacterial Agents; Cephalosporins; Critical Illness; Fatal Outcome; Hemofiltration; Humans; Male; Middle Aged; Pneumonia	2018
Influence of antibiotic pressure on multi-drug resistant Antimicrobial resistance and infection control, 2019, Volume: 8 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carbapenems; Cephalosporins; Critical Illness; Drug Resistance, Multiple, Bacterial; Female; Humans; Intensive Care Units; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Prospective Studies	2019
Optimizing ceftolozane-tazobactam dosage in critically ill patients during continuous venovenous hemodiafiltration. Critical care (London, England), 2019, 04-26, Volume: 23, Issue:1 Topics: Aged; Anti-Bacterial Agents; Cephalosporins; Critical Illness; Dose-Response Relationship, Drug; Hemofiltration; Humans; Male; Tazobactam	2019
Successful treatment with cefiderocol for compassionate use in a critically ill patient with XDR Acinetobacter baumannii and KPC-producing Klebsiella pneumoniae: a case report. The Journal of antimicrobial chemotherapy, 2019, 11-01, Volume: 74, Issue:11 Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Anti-Bacterial Agents; Cefiderocol; Cephalosporins; Compassionate Use Trials; Critical Illness; Drug Resistance, Multiple, Bacterial; Humans; Influenza, Human; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Pneumonia; Treatment Outcome	2019
Treatment of Rhizobium radiobacter bacteremia in a critically ill trauma patient. The Annals of pharmacotherapy, 2013, Volume: 47, Issue:11 Topics: Adult; Agrobacterium tumefaciens; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Critical Illness; Female; Humans; Opportunistic Infections; Treatment Outcome; Wounds and Injuries	2013
Treatment of Chryseobacterium indologenes ventilator-associated pneumonia in a critically ill trauma patient. The Annals of pharmacotherapy, 2013, Volume: 47, Issue:12 Topics: Aged; Anti-Bacterial Agents; Aza Compounds; Cefepime; Cephalosporins; Chryseobacterium; Critical Illness; Flavobacteriaceae Infections; Fluoroquinolones; Humans; Intensive Care Units; Male; Moxifloxacin; Pneumonia, Ventilator-Associated; Quinolines; Radiography; Wounds and Injuries	2013
Ceftolozane-Tazobactam Pharmacokinetics in a Critically Ill Patient on Continuous Venovenous Hemofiltration. Antimicrobial agents and chemotherapy, 2015, Dec-28, Volume: 60, Issue:3 Topics: Anti-Bacterial Agents; Cephalosporins; Critical Illness; Drug Resistance, Multiple, Bacterial; Hemofiltration; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Prospective Studies; Prosthesis-Related Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2015
Comparative Incidence of Acute Kidney Injury in Critically Ill Patients Receiving Vancomycin with Concomitant Piperacillin-Tazobactam or Cefepime: A Retrospective Cohort Study. Pharmacotherapy, 2016, Volume: 36, Issue:5 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Arkansas; Cefepime; Cephalosporins; Critical Illness; Drug Therapy, Combination; Female; Humans; Incidence; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Vancomycin	2016
Treatment of multidrug-resistant Pseudomonas aeruginosa with ceftolozane/tazobactam in a critically ill patient receiving continuous venovenous haemodiafiltration. International journal of antimicrobial agents, 2016, Volume: 48, Issue:3 Topics: Aged; Anti-Infective Agents, Urinary; beta-Lactamase Inhibitors; Cephalosporins; Chromatography, High Pressure Liquid; Critical Illness; Drug Resistance, Multiple, Bacterial; Hemofiltration; Humans; Male; Penicillanic Acid; Plasma; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Treatment Outcome; United States	2016
Influence of antipseudomonal agents on Pseudomonas aeruginosa colonization and acquisition of resistance in critically ill medical patients. Intensive care medicine, 2009, Volume: 35, Issue:3 Topics: Adult; Cephalosporins; Critical Illness; Cross Infection; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Female; Genes, Viral; Genotype; Humans; Intensive Care Units; Male; Pharynx; Piperacillin; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Rectum; Respiratory Mucosa	2009
Unexpected immune hemolytic anemia in an intensive care ward patient. American journal of hematology, 2010, Volume: 85, Issue:3 Topics: Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; Cephalosporins; Critical Illness; Hepatitis C, Chronic; Humans; Hyperbilirubinemia; Intensive Care Units; Liver Diseases, Alcoholic; Male; Middle Aged; Spherocytes	2010
Cefepime-associated thrombocytopenia in a critically ill patient. International journal of clinical pharmacy, 2011, Volume: 33, Issue:6 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cefepime; Cephalosporins; Critical Illness; Cross Infection; Humans; Intensive Care Units; Male; Middle Aged; Pneumothorax; Rhabdomyolysis; Sepsis; Thrombocytopenia	2011
What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance. International journal of antimicrobial agents, 2012, Volume: 39, Issue:6 Topics: Anti-Bacterial Agents; Carbapenems; Cephalosporins; Critical Illness; Cross Infection; Doripenem; Humans; Kidney; Metabolic Clearance Rate; Pneumonia; Pneumonia, Ventilator-Associated; Randomized Controlled Trials as Topic	2012
Cefepime and continuous renal replacement therapy (CRRT): in vitro permeability of two CRRT membranes and pharmacokinetics in four critically ill patients. Clinical therapeutics, 2005, Volume: 27, Issue:5 Topics: Acrylic Resins; Acrylonitrile; Adolescent; Aged; Anti-Bacterial Agents; Area Under Curve; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Critical Illness; Hemofiltration; Humans; Intensive Care Units; Male; Membranes, Artificial; Metabolic Clearance Rate; Middle Aged; Permeability; Polymers; Sulfones	2005
Population pharmacokinetics and pharmacodynamics of cefpirome in critically ill patients against Gram-negative bacteria. Intensive care medicine, 2007, Volume: 33, Issue:5 Topics: Adult; Aged; Anti-Bacterial Agents; Cefpirome; Cephalosporins; Creatinine; Critical Illness; Dose-Response Relationship, Drug; Female; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Intensive Care Units; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Monte Carlo Method	2007
Intermittent bolus dosing of ceftazidime in critically ill patients. The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:2 Topics: Adult; Aged; Ceftazidime; Cephalosporins; Critical Illness; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Pneumonia	1997
Meropenem monotherapy as empiric treatment of nosocomial lower respiratory tract infection. Critical care medicine, 1998, Volume: 26, Issue:8 Topics: Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Critical Illness; Cross Infection; Drug Therapy, Combination; Humans; Meropenem; Pneumonia, Bacterial; Severity of Illness Index; Thienamycins; Tobramycin; Treatment Outcome	1998
Use of in vitro models of haemofiltration and haemodiafiltration to estimate dosage regimens for critically ill patients prescribed cefpirome. Journal of clinical pharmacy and therapeutics, 1998, Volume: 23, Issue:5 Topics: Cefpirome; Cephalosporins; Chromatography, High Pressure Liquid; Critical Illness; Hemodiafiltration; Hemofiltration; Humans; In Vitro Techniques; Membranes, Artificial; Models, Biological; Renal Replacement Therapy	1998
The pharmacokinetics of ceftazidime during hemodiafiltration in critically ill patients. Artificial organs, 1999, Volume: 23, Issue:2 Topics: Aged; Anuria; Ceftazidime; Cephalosporins; Critical Illness; Female; Hemodiafiltration; Humans; Male; Middle Aged	1999
Altered pharmacokinetics of ceftazidime in critically ill patients. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:7 Topics: Adult; Aged; Ceftazidime; Cephalosporins; Critical Illness; Edema; Female; Half-Life; Humans; Male; Middle Aged; Prospective Studies	1999
Low cefpirome levels during twice daily dosing in critically ill septic patients: pharmacokinetic modelling calls for more frequent dosing. Intensive care medicine, 2001, Volume: 27, Issue:2 Topics: Adult; Aged; APACHE; Area Under Curve; Cefpirome; Cephalosporins; Critical Illness; Female; Half-Life; Humans; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Prospective Studies; Sepsis; Treatment Outcome	2001
[Cefotaxime, twenty years later. Observational study in critically ill patients]. Enfermedades infecciosas y microbiologia clinica, 2001, Volume: 19, Issue:5 Topics: Antibiotic Prophylaxis; Cefotaxime; Cephalosporins; Community-Acquired Infections; Critical Illness; Cross Infection; Drug Utilization; Humans; Intensive Care Units; Prospective Studies; Spain	2001
Clearance of ceftazidime during continuous venovenous haemofiltration in critically ill patients. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:1 Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Area Under Curve; Ceftazidime; Cephalosporins; Critical Illness; Drug Administration Schedule; Female; Hemofiltration; Humans; Male; Metabolic Clearance Rate; Middle Aged; Prospective Studies	2002