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cephaloridine and Necrosis

cephaloridine has been researched along with Necrosis in 9 studies

Cephaloridine: A cephalosporin antibiotic.
cefaloridine : A cephalosporin compound having pyridinium-1-ylmethyl and 2-thienylacetamido side-groups. A first-generation semisynthetic derivative of cephalosporin C.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Cephaloridine produces proximal tubular necrosis in the rabbit kidney."3.68Effect of verapamil on cephaloridine nephrotoxicity in the rabbit. ( Browning, MC, 1990)
"The ability of large doses of exogenous angiotensin II to cause widespread multifocal microscopic myocardial necrosis in the rabbit has been confirmed."3.65Angiotensin- and norepinephrine-induced myocardial lesions: experimental and clinical studies in rabbits and man. ( Brown, JJ; Gavras, H; Gray, B; Kremer, D; Lever, AF; MacAdam, RF; medina, A; Morton, JJ; Robertson, JI, 1975)
", the LD50 of NBBA was more than 3,000 mg/kg, i."1.29Protective effect of N-acyl amino acids (NAAs) on cephaloridine (CER) nephrotoxicity in rabbits. ( Hirouchi, Y; Hori, R; Inui, K; Kamiya, A; Kawahara, Y; Naganuma, H; Okada, R, 1993)
"Nephrotoxicity of cefodizime sodium (THR-221), a new cephem antibiotic, was studied in rats by comparing its toxic effect with those of other cephem antibiotics including cephaloridine (CER), cefazolin (CEZ) and cefmetazol (CMZ)."1.27[Nephrotoxicity of cefodizime sodium in rats--single and 14-day repeated intravenous administration]. ( Hayashi, T; Irimura, K; Kuwata, M; Maruden, A; Morita, K, 1988)
" The present report describes the effects of transient ureteral obstruction, which increases intracellular concentrations of secreted organic anions, on the cortical uptake and the proximal tubular toxicity of several cephalosporins given in mildly toxic doses."1.26Effects of ureteral obstruction on the toxicity of cephalosporins in the rabbit kidney. ( Hsu, CY; Prime, DJ; Tune, BM; Wang, PL, 1982)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, PL1
Prime, DJ1
Hsu, CY1
Tune, BM1
Hirouchi, Y1
Naganuma, H1
Kawahara, Y1
Okada, R1
Kamiya, A1
Inui, K1
Hori, R1
Gavras, H2
Kremer, D1
Brown, JJ1
Gray, B1
Lever, AF1
MacAdam, RF2
medina, A1
Morton, JJ1
Robertson, JI1
McMurtry, RJ1
Mitchell, JR1
Browning, MC1
Hayashi, T1
Maruden, A1
Irimura, K1
Kuwata, M1
Morita, K1
Lawson, DH1
Singh, MH1
Hartz, S1
Turnbull, D1
Linton, AL1
Wesson, LG1
Duckett, S1
Boyd, JF1
Butcher, BT1
Stewart, GT1

Other Studies

9 other studies available for cephaloridine and Necrosis

ArticleYear
Effects of ureteral obstruction on the toxicity of cephalosporins in the rabbit kidney.
    The Journal of infectious diseases, 1982, Volume: 145, Issue:4

    Topics: Animals; Cefaclor; Cefazolin; Cephaloglycin; Cephaloridine; Cephalosporins; Constriction; Female; Ki

1982
Protective effect of N-acyl amino acids (NAAs) on cephaloridine (CER) nephrotoxicity in rabbits.
    Japanese journal of pharmacology, 1993, Volume: 63, Issue:4

    Topics: Alanine; Amino Acids; Animals; Cephaloridine; Histocytochemistry; Injections, Intravenous; Kidney Tu

1993
Angiotensin- and norepinephrine-induced myocardial lesions: experimental and clinical studies in rabbits and man.
    American heart journal, 1975, Volume: 89, Issue:3

    Topics: Acute Kidney Injury; Adult; Angiotensin II; Animals; Cephaloridine; Female; Heart Diseases; Humans;

1975
Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, including furosemide and cephaloridine.
    Toxicology and applied pharmacology, 1977, Volume: 42, Issue:2

    Topics: Animals; Cephaloridine; Chemical and Drug Induced Liver Injury; Furans; Furosemide; In Vitro Techniq

1977
Effect of verapamil on cephaloridine nephrotoxicity in the rabbit.
    Toxicology and applied pharmacology, 1990, Volume: 103, Issue:3

    Topics: Animals; Calcium; Cephaloridine; Female; Kidney Cortex; Kidney Diseases; Kidney Tubular Necrosis, Ac

1990
[Nephrotoxicity of cefodizime sodium in rats--single and 14-day repeated intravenous administration].
    The Journal of toxicological sciences, 1988, Volume: 13 Suppl 1

    Topics: Animals; Cefazolin; Cefmetazole; Cefotaxime; Cephaloridine; Drug Administration Schedule; Drug Thera

1988
Effect of furosemide on antibiotic-induced renal damage in rats.
    The Journal of infectious diseases, 1972, Volume: 126, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Cephaloridine; Cephalothin; Colistin; Female; Furosemide; Glycerol;

1972
Renal ciliated epithelium in acute necrotizing glomerulitis.
    Archives of pathology, 1973, Volume: 96, Issue:2

    Topics: Acute Disease; Biopsy; Cephaloridine; Cephalothin; Cilia; Creatinine; Epithelial Cells; Female; Huma

1973
The nephrotoxicity and histology of cephaloridine and its polymers in rats.
    British journal of experimental pathology, 1971, Volume: 52, Issue:5

    Topics: Acute Kidney Injury; Animals; Ascites; Cephaloridine; Chemical Precipitation; Edema; Epithelium; Hem

1971