cephalomannine and Sarcoma-180

cephalomannine has been researched along with Sarcoma-180* in 1 studies

Other Studies

1 other study(ies) available for cephalomannine and Sarcoma-180

Article	Year
[Studies on the chemical constituents of Taxus yunnanensis]. Yao xue xue bao = Acta pharmaceutica Sinica, 1991, Volume: 26, Issue:10 The ethanolic extract of the bark of Taxus yunnanensis Cheng et L. K. Fu. showed significant antineoplastic effect on the transplantable tumors in mice. The life survival of P388 leukemic bearing mice was increased (84%) and the growth of B16 melanoma in mice was inhibited (53%). From this extract eight taxane diterpenoids and taxane alkaloids have been isolated. Seven of them have been identified as taxinine E(1), taxinine J(2), 1-acetoxy-5-deacetyl baccatin I(4), baccatin III(5), taxol (6), cephalomannine (7), 7-xylosyl-10-deacetyl taxol (8) from their physical and spectroscopic properties. A new taxane diterpenoid, named yunnanxane (3) was elucidated as taxa-4 (20), 11-diene-2 alpha, 5 alpha, 10 beta, 14 beta-tetraoln2 alpha,5 alpha,10 beta-triacetaten-14 beta-alpha-methyl-beta- hydroxylbutyratebyhighfield 1H NMR, 13C NMR, 1H-1HCOSY, 13C-1HCOSY, 13C-1HCOLOC and X-ray analysis. It showed the inhibitory effect on A2780 DDP, KB and HCT-8 cell line in vitro. All of the eight compounds were isolated from this species for the first time. Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Diterpenes; Drugs, Chinese Herbal; Melanoma, Experimental; Molecular Structure; Neoplasm Transplantation; Paclitaxel; Sarcoma 180; Taxoids; Tumor Cells, Cultured	1991

Article

Year

[Studies on the chemical constituents of Taxus yunnanensis].

Yao xue xue bao = Acta pharmaceutica Sinica, 1991, Volume: 26, Issue:10

The ethanolic extract of the bark of Taxus yunnanensis Cheng et L. K. Fu. showed significant antineoplastic effect on the transplantable tumors in mice. The life survival of P388 leukemic bearing mice was increased (84%) and the growth of B16 melanoma in mice was inhibited (53%). From this extract eight taxane diterpenoids and taxane alkaloids have been isolated. Seven of them have been identified as taxinine E(1), taxinine J(2), 1-acetoxy-5-deacetyl baccatin I(4), baccatin III(5), taxol (6), cephalomannine (7), 7-xylosyl-10-deacetyl taxol (8) from their physical and spectroscopic properties. A new taxane diterpenoid, named yunnanxane (3) was elucidated as taxa-4 (20), 11-diene-2 alpha, 5 alpha, 10 beta, 14 beta-tetraoln2 alpha,5 alpha,10 beta-triacetaten-14 beta-alpha-methyl-beta- hydroxylbutyratebyhighfield 1H NMR, 13C NMR, 1H-1HCOSY, 13C-1HCOSY, 13C-1HCOLOC and X-ray analysis. It showed the inhibitory effect on A2780 DDP, KB and HCT-8 cell line in vitro. All of the eight compounds were isolated from this species for the first time.

Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Diterpenes; Drugs, Chinese Herbal; Melanoma, Experimental; Molecular Structure; Neoplasm Transplantation; Paclitaxel; Sarcoma 180; Taxoids; Tumor Cells, Cultured

1991