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celiprolol and Angina Pectoris

celiprolol has been researched along with Angina Pectoris in 27 studies

Celiprolol: A cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity. It is used in the management of ANGINA PECTORIS and HYPERTENSION.

Angina Pectoris: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"The comparative antianginal effects and safety of propranolol and celiprolol, a highly beta 1-selective adrenoceptor blocker with selective partial beta 2-adrenoceptor agonist activity, were assessed in an international multicenter, placebo run-in, active control, double-blind, randomized, titration-to-effect study of 140 patients with stable, exercise-induced angina pectoris."9.07Comparison of celiprolol and propranolol in stable angina pectoris. Celiprolol International Angina Study Group. ( Eff, J; Frishman, WH; Greenberg, S; Heiman, M; Soberman, J, 1991)
"This double-blind, placebo-controlled, parallel, multicenter study was designed to evaluate the anti-anginal and anti-ischemic effects of celiprolol in patients with stable, exercise-induced angina pectoris."9.06Celiprolol in angina pectoris: a controlled study. ( Capone, P; Eff, J; Garutti, R; Godfrey, J, 1986)
"A multicenter, double-blind placebo controlled study was designed to examine the efficacy of celiprolol in exercise induced angina pectoris."9.06Celiprolol in the treatment of exercise induced angina pectoris. ( Capone, P; Mayol, R, 1986)
"Once-daily atenolol and celiprolol were compared in a placebo-controlled crossover study of 16 patients with stable angina pectoris."9.06Atenolol and celiprolol for stable angina pectoris. ( Dargie, HJ; Findlay, IN; Henderson, E; McLenachan, JM; Wilson, JT, 1988)
"Celiprolol was found to be an effective antianginal agent compared with placebo."7.76Celiprolol in angina pectoris. ( Frishman, WH; Soberman, JE, 1988)
"In 30 hypertensives with angina pectoris the acute action of beta-blockers Celiprolol and Metoprolol on the global and coronary haemodynamics was tested within cardiac catheter diagnostics."7.68[Acute changes of coronary and global hemodynamics in patients with angina pectoris and arterial hypertension caused by celiprolol and metoprolol]. ( Bruch, L; Franz, N; Gola, G; Heublein, B; Linss, G; Modersohn, D; Walde, T, 1990)
"In the present study, the beta-receptor-blocker Celiprolol was tested for its antianginal effects during an observation period of 12 months; 29 patients, both male and female, with definite coronary heart diseases, were subjected to this study."7.67[Treatment of coronary heart disease with the beta-1-receptor blocker celiprolol in a long-term study over a 12-month period]. ( Klinger, D, 1987)
"Celiprolol has shown equivalent antihypertensive efficacy to other beta-blockers, notably propranolol, atenolol, metoprolol and pindolol, in patients aged 18 to 75 years with mild to moderate essential hypertension."6.39Celiprolol. An evaluation of its pharmacological properties and clinical efficacy in the management of hypertension and angina pectoris. ( Dunn, CJ; Spencer, CM, 1995)
"Celiprolol has been demonstrated to have antianginal and anti-ischemic effects comparable with both propranolol and atenolol, with a decreased incidence of bradycardia noted in the celiprolol-treated cohorts."6.38Clinical performance and therapeutic potential of celiprolol in angina pectoris. ( Frishman, WH; Soberman, JE, 1989)
" If the apparent pharmacodynamic advantages of celiprolol are confirmed in well designed therapeutic trials then celiprolol should represent a definite advance in beta-adrenoceptor blocking therapy."6.37Celiprolol. A preliminary review of its pharmacodynamic and pharmacokinetic properties and its therapeutic use in hypertension and angina pectoris. ( Brogden, RN; Riddell, JG; Shanks, RG, 1987)
"The comparative antianginal effects and safety of propranolol and celiprolol, a highly beta 1-selective adrenoceptor blocker with selective partial beta 2-adrenoceptor agonist activity, were assessed in an international multicenter, placebo run-in, active control, double-blind, randomized, titration-to-effect study of 140 patients with stable, exercise-induced angina pectoris."5.07Comparison of celiprolol and propranolol in stable angina pectoris. Celiprolol International Angina Study Group. ( Eff, J; Frishman, WH; Greenberg, S; Heiman, M; Soberman, J, 1991)
"This double-blind, placebo-controlled, parallel, multicenter study was designed to evaluate the anti-anginal and anti-ischemic effects of celiprolol in patients with stable, exercise-induced angina pectoris."5.06Celiprolol in angina pectoris: a controlled study. ( Capone, P; Eff, J; Garutti, R; Godfrey, J, 1986)
"A multicenter, double-blind placebo controlled study was designed to examine the efficacy of celiprolol in exercise induced angina pectoris."5.06Celiprolol in the treatment of exercise induced angina pectoris. ( Capone, P; Mayol, R, 1986)
"The effects of once-daily dosing with celiprolol 200 mg, celiprolol 400 mg, and atenolol 100 mg have been studied in 19 male patients with chronic stable angina pectoris."5.06A single-blind randomized comparison of the 24-h antianginal efficacy of celiprolol versus atenolol. ( Jackson, NC; Lee, PS; Taylor, SH, 1986)
"Once-daily atenolol and celiprolol were compared in a placebo-controlled crossover study of 16 patients with stable angina pectoris."5.06Atenolol and celiprolol for stable angina pectoris. ( Dargie, HJ; Findlay, IN; Henderson, E; McLenachan, JM; Wilson, JT, 1988)
"Celiprolol (400 mg) and atenolol (100 mg) were given once a day to 16 patients with stable angina pectoris in a double blind placebo controlled crossover study."5.06Importance of ancillary properties of beta blockers in angina: a study of celiprolol and atenolol. ( Dargie, HJ; McLenachan, JM; Wilson, JT, 1988)
"The results of an extensive pre-clinical and clinical research programme indicate that celiprolol is a safe and effective treatment for both hypertension and angina pectoris."5.06Celiprolol--overview of 6 years of clinical trials experience. ( Hagen, NS; Lamon, KD; Pruss, TP, 1988)
"Celiprolol is a hydrophilic, beta 1-selective adrenoceptor antagonist with mild selective beta 2-agonist as well as weak vasodilator properties."3.77Celiprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in cardiovascular disease. ( Buckley, MM; Milne, RJ, 1991)
"Celiprolol was found to be an effective antianginal agent compared with placebo."3.76Celiprolol in angina pectoris. ( Frishman, WH; Soberman, JE, 1988)
" The adverse experience safety data derived from 18 double-blind trials (n = 2884) were evaluated."3.76Safety profile of celiprolol. ( Lamon, KD, 1988)
"In 30 hypertensives with angina pectoris the acute action of beta-blockers Celiprolol and Metoprolol on the global and coronary haemodynamics was tested within cardiac catheter diagnostics."3.68[Acute changes of coronary and global hemodynamics in patients with angina pectoris and arterial hypertension caused by celiprolol and metoprolol]. ( Bruch, L; Franz, N; Gola, G; Heublein, B; Linss, G; Modersohn, D; Walde, T, 1990)
"In the present study, the beta-receptor-blocker Celiprolol was tested for its antianginal effects during an observation period of 12 months; 29 patients, both male and female, with definite coronary heart diseases, were subjected to this study."3.67[Treatment of coronary heart disease with the beta-1-receptor blocker celiprolol in a long-term study over a 12-month period]. ( Klinger, D, 1987)
"Celiprolol is a novel beta 1 selective adrenoreceptor blocker with partial beta 2 agonism and direct vasodilator activity."2.67Cardiorespiratory and symptomatic variables during maximal and submaximal exercise in men with stable effort angina: a comparison of atenolol and celiprolol. ( Christie, J; Dargie, HJ; Ford, I; Grant, S; Henderson, E; MacFarlane, N; McCann, G; Norrie, J; Ray, SG, 1994)
"Celiprolol is a third generation beta blocking drug with intrinsic vasodilator effect."2.67[Celiprolol in the treatment of chronic stable angina]. ( Cuevas, G; Martínez, D; Román, O; Vargas, W, 1991)
"Celiprolol is a cardioselective beta-adrenoceptor antagonist with attributed cardiostimulant properties."2.66Comparative effects of metoprolol and celiprolol on cardiac hemodynamics and left ventricular volume at rest and during exercise-induced angina. ( Frais, MA; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1986)
"A new cardioselective betablocker, celiprolol (C) in a dosage of 100 mg t."2.65[Double-blind, placebo-controlled trial of propranolol vs celiprolol in stable effort angina: antianginal efficacy and side effects ]. ( Brandt, D; Fluch, N; Klein, W, 1982)
"Celiprolol has shown equivalent antihypertensive efficacy to other beta-blockers, notably propranolol, atenolol, metoprolol and pindolol, in patients aged 18 to 75 years with mild to moderate essential hypertension."2.39Celiprolol. An evaluation of its pharmacological properties and clinical efficacy in the management of hypertension and angina pectoris. ( Dunn, CJ; Spencer, CM, 1995)
"Celiprolol has been demonstrated to have antianginal and anti-ischemic effects comparable with both propranolol and atenolol, with a decreased incidence of bradycardia noted in the celiprolol-treated cohorts."2.38Clinical performance and therapeutic potential of celiprolol in angina pectoris. ( Frishman, WH; Soberman, JE, 1989)
" If the apparent pharmacodynamic advantages of celiprolol are confirmed in well designed therapeutic trials then celiprolol should represent a definite advance in beta-adrenoceptor blocking therapy."2.37Celiprolol. A preliminary review of its pharmacodynamic and pharmacokinetic properties and its therapeutic use in hypertension and angina pectoris. ( Brogden, RN; Riddell, JG; Shanks, RG, 1987)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199016 (59.26)18.7374
1990's11 (40.74)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Klein, W1
Fluch, N1
Brandt, D1
Ray, SG1
McCann, G1
Henderson, E2
MacFarlane, N1
Christie, J1
Norrie, J1
Ford, I1
Grant, S2
Dargie, HJ5
Dunn, CJ1
Spencer, CM1
Frishman, WH4
McLenachan, J2
Heiman, M1
Soberman, J1
Greenberg, S1
Eff, J3
Norris, RJ1
Silke, B2
Verma, SP2
Guy, S1
Román, O1
Cuevas, G1
Martínez, D1
Vargas, W1
Milne, RJ1
Buckley, MM1
McLenachan, JM4
Franz, N1
Modersohn, D1
Linss, G1
Heublein, B1
Gola, G1
Bruch, L1
Walde, T1
Godfrey, J1
Garutti, R1
Capone, P3
Mayol, R1
Jackson, NC1
Lee, PS1
Taylor, SH2
Soberman, JE2
Harston, WE1
Klinger, D1
Riddell, JG1
Shanks, RG1
Brogden, RN1
Findlay, IN1
Wilson, JT3
Wilson, J1
Dargie, H2
Lamon, KD2
Pruss, TP1
Hagen, NS1
Frais, MA1
Reynolds, G1

Reviews

9 reviews available for celiprolol and Angina Pectoris

ArticleYear
Celiprolol. An evaluation of its pharmacological properties and clinical efficacy in the management of hypertension and angina pectoris.
    Drugs & aging, 1995, Volume: 7, Issue:5

    Topics: Administration, Oral; Angina Pectoris; Antihypertensive Agents; Celiprolol; Humans; Hypertension; Ra

1995
Clinical perspective on celiprolol: cardioprotective potential.
    American heart journal, 1991, Volume: 121, Issue:2 Pt 2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Asthma; Blood Pressure; Celiprolol; Coronary Disease;

1991
Efficacy of celiprolol in hypertension and angina pectoris. Introduction.
    Cardiovascular drugs and therapy, 1991, Volume: 4 Suppl 6

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Celiprolol; Humans; Hypertens

1991
Celiprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in cardiovascular disease.
    Drugs, 1991, Volume: 41, Issue:6

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Antihypertensive Agents; Celiprolol; Dogs; He

1991
A review of the clinical experience with celiprolol in angina.
    American heart journal, 1991, Volume: 121, Issue:2 Pt 2

    Topics: Angina Pectoris; Antihypertensive Agents; Celiprolol; Humans; Propanolamines

1991
Clinical performance and therapeutic potential of celiprolol in angina pectoris.
    Journal of cardiovascular pharmacology, 1989, Volume: 14 Suppl 7

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Celiprolol; Humans; Propanolamines

1989
Celiprolol. A preliminary review of its pharmacodynamic and pharmacokinetic properties and its therapeutic use in hypertension and angina pectoris.
    Drugs, 1987, Volume: 34, Issue:4

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Celiprolol; Hemodynamics; Humans; Hypertensio

1987
Celiprolol in angina pectoris.
    American heart journal, 1988, Volume: 116, Issue:5 Pt 2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Celiprolol; Clinical Trials as Topic; Double

1988
Safety profile of celiprolol.
    American heart journal, 1988, Volume: 116, Issue:5 Pt 2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Atenolol; Celiprolol; Chlorth

1988

Trials

19 trials available for celiprolol and Angina Pectoris

ArticleYear
[Double-blind, placebo-controlled trial of propranolol vs celiprolol in stable effort angina: antianginal efficacy and side effects ].
    Wiener klinische Wochenschrift, 1982, May-14, Volume: 94, Issue:10

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Celiprolol; Clinical Trials as Topic;

1982
Cardiorespiratory and symptomatic variables during maximal and submaximal exercise in men with stable effort angina: a comparison of atenolol and celiprolol.
    European heart journal, 1994, Volume: 15, Issue:11

    Topics: Aged; Angina Pectoris; Atenolol; Celiprolol; Cross-Over Studies; Double-Blind Method; Electrocardiog

1994
Angina, ischemia, and effort tolerance with vasodilating beta-blockers.
    American heart journal, 1991, Volume: 121, Issue:3 Pt 2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Cardiac Output; Celiprolol; Coronary Disease

1991
Comparison of celiprolol and propranolol in stable angina pectoris. Celiprolol International Angina Study Group.
    The American journal of cardiology, 1991, Apr-01, Volume: 67, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Analysis of Variance; Angina Pectoris;

1991
Hemodynamic interactions of a new beta blocker, celiprolol, with nifedipine in angina pectoris.
    Cardiovascular drugs and therapy, 1991, Volume: 5, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Celiprolol; Drug Interactions; Drug Therapy, Co

1991
[Celiprolol in the treatment of chronic stable angina].
    Revista medica de Chile, 1991, Volume: 119, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Celiprolol; Female; He

1991
Celiprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in cardiovascular disease.
    Drugs, 1991, Volume: 41, Issue:6

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Antihypertensive Agents; Celiprolol; Dogs; He

1991
Celiprolol in angina pectoris: a controlled study.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 4

    Topics: Adult; Aged; Angina Pectoris; Celiprolol; Clinical Trials as Topic; Double-Blind Method; Electrocard

1986
Celiprolol in the treatment of exercise induced angina pectoris.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Celiprolol; Clinical Trials as Topic; Dou

1986
A single-blind randomized comparison of the 24-h antianginal efficacy of celiprolol versus atenolol.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 4

    Topics: Angina Pectoris; Atenolol; Celiprolol; Clinical Trials as Topic; Exercise Test; Humans; Propanolamin

1986
A double blind placebo controlled study of celiprolol in the treatment of angina pectoris.
    British journal of clinical practice. Supplement, 1985, Volume: 40

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Celiprolol; Clinical Trials as Topic; Double-Blind Met

1985
Atenolol and celiprolol for stable angina pectoris.
    The American journal of cardiology, 1988, Feb-10, Volume: 61, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Atenolol; Celiprolol; Clinical Trials as

1988
Importance of ancillary properties of beta blockers in angina: a study of celiprolol and atenolol.
    British heart journal, 1988, Volume: 59, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Atenolol; Blood Pressure; Celiprolol; Cli

1988
Celiprolol in angina pectoris.
    American heart journal, 1988, Volume: 116, Issue:5 Pt 2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Celiprolol; Clinical Trials as Topic; Double

1988
Improved left ventricular function during exercise: a comparison of celiprolol and atenolol.
    American heart journal, 1988, Volume: 116, Issue:5 Pt 2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Cardiac Output; Celiprolol; Exercise; Exerci

1988
Safety profile of celiprolol.
    American heart journal, 1988, Volume: 116, Issue:5 Pt 2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Atenolol; Celiprolol; Chlorth

1988
Celiprolol--overview of 6 years of clinical trials experience.
    The Journal of international medical research, 1988, Volume: 16 Suppl 1

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Celiprolol; Clinical Trials as Topic; Humans; Hyperten

1988
Celiprolol and atenolol in angina--effects on left ventricular function.
    The Journal of international medical research, 1988, Volume: 16 Suppl 1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Atenolol; Celiprolol; Clinical Trials as

1988
Comparative effects of metoprolol and celiprolol on cardiac hemodynamics and left ventricular volume at rest and during exercise-induced angina.
    Clinical pharmacology and therapeutics, 1986, Volume: 39, Issue:1

    Topics: Angina Pectoris; Celiprolol; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Evaluat

1986

Other Studies

2 other studies available for celiprolol and Angina Pectoris

ArticleYear
[Acute changes of coronary and global hemodynamics in patients with angina pectoris and arterial hypertension caused by celiprolol and metoprolol].
    Radiologia diagnostica, 1990, Volume: 31, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Celiprolol; Hemodynamics; Humans; Hypertension;

1990
[Treatment of coronary heart disease with the beta-1-receptor blocker celiprolol in a long-term study over a 12-month period].
    Wiener medizinische Wochenschrift (1946), 1987, Jun-30, Volume: 137, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Celiprolol; Coronary Disease; Electrocard

1987