celecoxib has been researched along with Thyroid Neoplasms in 6 studies
Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Celecoxib has a good therapeutic potential for MTC to prevent metastasis growth, and its anti-tumoral effect is, at least in part, independent of PGE(2)." | 1.35 | Anti-tumoral effect of a celecoxib low dose on a model of human medullary thyroid cancer in nude mice. ( Cohen, R; Jullienne, A; Lausson, S; Lepoivre, M; Quidville, V; Segond, N; Tebbi, A, 2009) |
| "In three human thyroid cancer cell lines, OSU-03012 inhibited cell proliferation with reduced AKT phosphorylation by PDK1." | 1.34 | 2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase. ( Chen, CS; Espinosa, AV; Guerra, M; Kirschner, LS; Kulp, SK; Porchia, LM; Ringel, MD; Saji, M; Shinohara, M; Wang, YC; Zhang, Y, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Q | 1 |
| Meng, X | 1 |
| Zheng, G | 1 |
| Chen, G | 1 |
| Pang, R | 1 |
| Hua, T | 1 |
| Yang, S | 1 |
| Quidville, V | 1 |
| Segond, N | 1 |
| Tebbi, A | 1 |
| Cohen, R | 1 |
| Jullienne, A | 1 |
| Lepoivre, M | 1 |
| Lausson, S | 1 |
| Grushka, JR | 1 |
| Ryckman, J | 1 |
| Mueller, C | 1 |
| Roessingh, Ade B | 1 |
| Walton, JM | 1 |
| St Vil, D | 1 |
| Laberge, JM | 1 |
| Bernard, C | 1 |
| Nguyen, VH | 1 |
| Puligandla, PS | 1 |
| Vivaldi, A | 1 |
| Ciampi, R | 1 |
| Tacito, A | 1 |
| Molinaro, E | 1 |
| Agate, L | 1 |
| Bottici, V | 1 |
| Pinchera, A | 1 |
| Collecchi, P | 1 |
| Elisei, R | 1 |
| Mrozek, E | 1 |
| Kloos, RT | 1 |
| Ringel, MD | 2 |
| Kresty, L | 1 |
| Snider, P | 1 |
| Arbogast, D | 1 |
| Kies, M | 1 |
| Munden, R | 1 |
| Busaidy, N | 1 |
| Klein, MJ | 1 |
| Sherman, SI | 1 |
| Shah, MH | 1 |
| Porchia, LM | 1 |
| Guerra, M | 1 |
| Wang, YC | 1 |
| Zhang, Y | 1 |
| Espinosa, AV | 1 |
| Shinohara, M | 1 |
| Kulp, SK | 1 |
| Kirschner, LS | 1 |
| Saji, M | 1 |
| Chen, CS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Study Of Celecoxib In Metastatic Differentiated Thyroid Carcinoma[NCT00061906] | Phase 2 | 25 participants (Actual) | Interventional | 2003-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for celecoxib and Thyroid Neoplasms
| Article | Year |
|---|---|
Spindle epithelial tumor with thymus-like elements of the thyroid: a multi-institutional case series and review of the literature.
Topics: Abscess; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma; Celecoxib; Ch | 2009 |
1 trial available for celecoxib and Thyroid Neoplasms
| Article | Year |
|---|---|
Phase II study of celecoxib in metastatic differentiated thyroid carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Hu | 2006 |
4 other studies available for celecoxib and Thyroid Neoplasms
| Article | Year |
|---|---|
Antitumor activity of celecoxib, a selective cyclooxygenase-2 inhibitor, in medullary thyroid carcinoma.
Topics: Apoptosis; Carcinoma, Neuroendocrine; Celecoxib; Cell Cycle; Cell Line, Tumor; Cell Proliferation; C | 2014 |
Anti-tumoral effect of a celecoxib low dose on a model of human medullary thyroid cancer in nude mice.
Topics: Animals; Blotting, Western; Carcinoma, Medullary; Caspase 3; Celecoxib; Cell Line, Tumor; Cell Proli | 2009 |
Celecoxib, a cyclooxygenase-2 inhibitor, potentiates the chemotherapic effect of vinorelbine in the medullary thyroid cancer TT cell line.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamil | 2012 |
2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Prol | 2007 |