celecoxib has been researched along with Teeth, Impacted in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary outcome chosen was postoperative pain, which was evaluated using the visual analogue scale (VAS) score recorded by each patient." | 2.90 | Evaluation of the efficacy of celecoxib and ibuprofen on postoperative pain, swelling, and mouth opening after surgical removal of impacted third molars: a randomized, controlled clinical trial. ( Cicciù, M; Isola, G; Matarese, G; Matarese, M; Ramaglia, L, 2019) |
| "Celecoxib was the most effective analgesic of the three studied drugs in controlling postoperative pain after mandibular third molar extraction in our subjects." | 2.87 | Comparative Analgesic Effects of Ibuprofen, Celecoxib and Tramadol after third Molar Surgery: A Randomized Double Blind Controlled Trial. ( Akinbade, AO; Ndukwe, KC; Owotade, FJ, 2018) |
| " The incidence of treatment-related, all-cause adverse events was slightly lower in patients receiving celecoxib 200 mg (20." | 2.77 | Efficacy and safety of additional 200-mg dose of celecoxib in adult patients with postoperative pain following extraction of impacted third mandibular molar: a multicenter, randomized, double-blind, placebo-controlled, phase II study in Japan. ( Kaneko, A; Machii, K; Ohkura, M; Ohta, H; Saito, K; Suzuki, M, 2012) |
| " The onset of analgesia (PID >or= 1) for all CS-706 doses occurred within 1 hour after dosing (P<0." | 2.73 | A randomized, double-blind, celecoxib- and placebo-controlled study of the effectiveness of CS-706 in acute postoperative dental pain. ( Bandy, DP; Daniels, SE; Desjardins, PJ; Lawson, JE; Link, AJ; Moberly, JB; Truitt, KE; Xu, J, 2007) |
| " Pain intensity was measured using the categorical scale and the primary efficacy variable was the summed pain intensity difference over 8 hours after dosing (SPID-8)." | 2.73 | Lumiracoxib 400 mg compared with celecoxib 400 mg and placebo for treating pain following dental surgery: a randomized, controlled trial. ( Davis, N; Fricke, J; Krammer, G; Yu, V, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akinbade, AO | 1 |
| Ndukwe, KC | 1 |
| Owotade, FJ | 1 |
| Isola, G | 1 |
| Matarese, M | 1 |
| Ramaglia, L | 1 |
| Cicciù, M | 1 |
| Matarese, G | 1 |
| Saito, K | 1 |
| Kaneko, A | 1 |
| Machii, K | 1 |
| Ohta, H | 1 |
| Ohkura, M | 1 |
| Suzuki, M | 1 |
| Moberly, JB | 1 |
| Xu, J | 1 |
| Desjardins, PJ | 1 |
| Daniels, SE | 1 |
| Bandy, DP | 1 |
| Lawson, JE | 1 |
| Link, AJ | 1 |
| Truitt, KE | 1 |
| Fricke, J | 1 |
| Davis, N | 1 |
| Yu, V | 1 |
| Krammer, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Multicenter, Comparative Study To Evaluate Efficacy And Safety Of An Additional Dose Of Celecoxib (YM177) In The Treatment Of Acute Pain After Oral Surgery Lateral Mandibular Impacted Third Molar Tooth Extraction[NCT01062113] | Phase 2 | 255 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| A Randomized, Double-blind, Double-dummy, Parallel Group, Single-center Study Evaluating the Analgesic Effect of Single Doses of Lumiracoxib 400 mg, Celecoxib 400 mg and Placebo in the Treatment of Post-dental Surgery Pain[NCT00348491] | Phase 4 | 364 participants | Interventional | 2006-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The differences in PI were obtained by subtracting the PI at each time point from the Baseline PI score. (NCT01062113)
Timeframe: Pre-additional dose (baseline) and 2 hours post-additional dose
| Intervention | mm (Mean) |
|---|---|
| Additional Dose Celecoxib 200 mg | 33.4 |
| Additional Dose Placebo | 12.3 |
"Patient's impression was assessed by self-report and was entered in the patient diary, based on the following categories: Excellent, Good, Fair and Poor.~Efficacy rate was calculated from the following formula, The number of participants assessed as Excellent or Good over total participants multiplied by 100." (NCT01062113)
Timeframe: 2 hours post-additional dose
| Intervention | percentage of participants (Number) |
|---|---|
| Additional Dose Celecoxib 200 mg | 64.1 |
| Additional Dose Placebo | 25.9 |
The Pain intensity was recorded on the 100 mm VAS in the patient diary, where 0 mm=no pain, 100 mm=unbearable maximal pain. (NCT01062113)
Timeframe: 2 hours post-additional dose
| Intervention | mm (Mean) |
|---|---|
| Additional Dose Celecoxib 200 mg | 35.8 |
| Additional Dose Placebo | 51.9 |
"Pain intensity was entered in the patient diary on the following categories: No pain, Mild pain, Moderate pain and Severe pain." (NCT01062113)
Timeframe: 2 hours after additional dose
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| None | Mild | Moderate | Severe | |
| Additional Dose Celecoxib 200mg | 11 | 34 | 18 | 1 |
| Additional Dose Placebo | 3 | 24 | 28 | 3 |
5 trials available for celecoxib and Teeth, Impacted
| Article | Year |
|---|---|
Comparative Analgesic Effects of Ibuprofen, Celecoxib and Tramadol after third Molar Surgery: A Randomized Double Blind Controlled Trial.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Double-Blind Meth | 2018 |
Evaluation of the efficacy of celecoxib and ibuprofen on postoperative pain, swelling, and mouth opening after surgical removal of impacted third molars: a randomized, controlled clinical trial.
Topics: Celecoxib; Double-Blind Method; Humans; Ibuprofen; Molar, Third; Pain, Postoperative; Tooth Extracti | 2019 |
Efficacy and safety of additional 200-mg dose of celecoxib in adult patients with postoperative pain following extraction of impacted third mandibular molar: a multicenter, randomized, double-blind, placebo-controlled, phase II study in Japan.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind | 2012 |
A randomized, double-blind, celecoxib- and placebo-controlled study of the effectiveness of CS-706 in acute postoperative dental pain.
Topics: Acute Disease; Adolescent; Adult; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship | 2007 |
Lumiracoxib 400 mg compared with celecoxib 400 mg and placebo for treating pain following dental surgery: a randomized, controlled trial.
Topics: Adolescent; Adult; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Admin | 2008 |