Page last updated: 2024-10-24

celecoxib and Stevens-Johnson Syndrome

celecoxib has been researched along with Stevens-Johnson Syndrome in 7 studies

Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study is to review cases of Stevens-Johnson syndrome and toxic epidermal necrolysis reported to the FDA associated with the use of the selective COX-2 inhibitor NSAIDs celecoxib, rofecoxib and valdecoxib, and to compare reporting rates of the two conditions associated with these drugs to each other, meloxicam (an oxicam NSAID that came on the US market at a similar time) and the background incidence rate."3.73Comparison of reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis in association with selective COX-2 inhibitors. ( Bonnel, R; Brinker, A; Governale, L; Karwoski, C; La Grenade, L; Lee, L; Weaver, J, 2005)
"A 41-year-old woman was given celecoxib (Celebrex) for the treatment of carpal tunnel syndrome."3.71Toxic epidermal necrolysis due to administration of celecoxib (Celebrex). ( Friedman, B; Law, E; Orlet, HK; Still, JM, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berger, P1
Dwyer, D1
Corallo, CE1
Friedman, B1
Orlet, HK1
Still, JM1
Law, E1
Giglio, P1
Perna, AG1
Woodruff, CA1
Markus, RF1
Hsu, S1
Schmutz, JL1
Barbaud, A1
Trechot, P1
La Grenade, L1
Lee, L1
Weaver, J1
Bonnel, R1
Karwoski, C1
Governale, L1
Brinker, A1
Layton, D1
Marshall, V1
Boshier, A1
Friedmann, P1
Shakir, SA1

Reviews

1 review available for celecoxib and Stevens-Johnson Syndrome

ArticleYear
Toxic epidermal necrolysis as a complication of treatment with celecoxib.
    Dermatology online journal, 2003, Volume: 9, Issue:5

    Topics: Aged; Aged, 80 and over; Celecoxib; Chemical and Drug Induced Liver Injury; Cyclooxygenase Inhibitor

2003

Other Studies

6 other studies available for celecoxib and Stevens-Johnson Syndrome

ArticleYear
Toxic epidermal necrolysis after celecoxib therapy.
    Pharmacotherapy, 2002, Volume: 22, Issue:9

    Topics: Aged; Aged, 80 and over; Celecoxib; Cyclooxygenase Inhibitors; Female; Humans; Osteoarthritis; Pyraz

2002
Toxic epidermal necrolysis due to administration of celecoxib (Celebrex).
    Southern medical journal, 2002, Volume: 95, Issue:10

    Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Carpal Tunnel Syndrome; Celec

2002
Toxic epidermal necrolysis due to administration of celecoxib (Celebrex).
    Southern medical journal, 2003, Volume: 96, Issue:3

    Topics: Celecoxib; Cyclooxygenase Inhibitors; Drug Eruptions; Humans; Pyrazoles; Stevens-Johnson Syndrome; S

2003
[Toxic epidermal necrolysis and celecoxib (Celebrex)].
    Annales de dermatologie et de venereologie, 2004, Volume: 131, Issue:1 Pt 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Humans; Pyrazoles; Stevens-Johnson Syndrome; Sul

2004
Comparison of reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis in association with selective COX-2 inhibitors.
    Drug safety, 2005, Volume: 28, Issue:10

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Celecoxib; Cycl

2005
Serious skin reactions and selective COX-2 inhibitors: a case series from prescription-event monitoring in England.
    Drug safety, 2006, Volume: 29, Issue:8

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Celecoxib; Cyclooxygenase 2

2006