celecoxib has been researched along with Status Epilepticus in 4 studies
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the effect of cyclooxygenase -2 selective inhibitor celecoxib on the expression of major vault protein ( MVP) in the brain of rats with status epilepticus and its possible roles in the treatment of refractory epilepsy." | 7.83 | [Effects of cyclooxygenase-2 selective inhibitor celecoxib on the expression of major vault protein in rats with status epilepticus]. ( Huang, SP; Jiang, YS; Li, D; Liu, Y; Song, TT; Wang, XY; Yang, L, 2016) |
| "The COX-2 inhibitor celecoxib decreased neuronal excitability and prevented epileptogenesis in pilocarpine-induced status epilepticus rats." | 7.74 | Cyclooxygenase-2 inhibitor inhibits hippocampal synaptic reorganization in pilocarpine-induced status epilepticus rats. ( Lei, GF; Liu, CX; Sun, RP; Yang, L; Zhang, HJ, 2008) |
| "To study the effect of cyclooxygenase -2 selective inhibitor celecoxib on the expression of major vault protein ( MVP) in the brain of rats with status epilepticus and its possible roles in the treatment of refractory epilepsy." | 3.83 | [Effects of cyclooxygenase-2 selective inhibitor celecoxib on the expression of major vault protein in rats with status epilepticus]. ( Huang, SP; Jiang, YS; Li, D; Liu, Y; Song, TT; Wang, XY; Yang, L, 2016) |
| "The COX-2 inhibitor celecoxib decreased neuronal excitability and prevented epileptogenesis in pilocarpine-induced status epilepticus rats." | 3.74 | Cyclooxygenase-2 inhibitor inhibits hippocampal synaptic reorganization in pilocarpine-induced status epilepticus rats. ( Lei, GF; Liu, CX; Sun, RP; Yang, L; Zhang, HJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, TT | 1 |
| Li, D | 1 |
| Huang, SP | 1 |
| Yang, L | 2 |
| Wang, XY | 1 |
| Jiang, YS | 1 |
| Liu, Y | 1 |
| Zhang, HJ | 1 |
| Sun, RP | 1 |
| Lei, GF | 1 |
| Liu, CX | 1 |
| Zibell, G | 1 |
| Unkrüer, B | 1 |
| Pekcec, A | 1 |
| Hartz, AM | 1 |
| Bauer, B | 1 |
| Miller, DS | 1 |
| Potschka, H | 1 |
| Jung, KH | 1 |
| Chu, K | 1 |
| Lee, ST | 1 |
| Kim, J | 1 |
| Sinn, DI | 1 |
| Kim, JM | 1 |
| Park, DK | 1 |
| Lee, JJ | 1 |
| Kim, SU | 1 |
| Kim, M | 1 |
| Lee, SK | 1 |
| Roh, JK | 1 |
4 other studies available for celecoxib and Status Epilepticus
| Article | Year |
|---|---|
[Effects of cyclooxygenase-2 selective inhibitor celecoxib on the expression of major vault protein in rats with status epilepticus].
Topics: Animals; Blotting, Western; Brain; Celecoxib; Cyclooxygenase 2 Inhibitors; Immunohistochemistry; Mal | 2016 |
Cyclooxygenase-2 inhibitor inhibits hippocampal synaptic reorganization in pilocarpine-induced status epilepticus rats.
Topics: Animals; Blotting, Western; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models | 2008 |
Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition.
Topics: Animals; Arachidonic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barr | 2009 |
Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Disease Models, Animal; Hippocampus; Male; Muscarinic | 2006 |