Page last updated: 2024-10-24

celecoxib and Pregnancy

celecoxib has been researched along with Pregnancy in 46 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effectiveness of celecoxib for pain relief and antipyresis during second trimester abortion using sublingual misoprostol."9.27Effectiveness of celecoxib for pain relief and antipyresis in second trimester medical abortions with misoprostol: a randomized controlled trial. ( Choobun, T; Tintara, H; Voradithi, P, 2018)
"Celecoxib administration for more than 48 hours in the second trimester of pregnancy might be safe and tolerable in terms of fetal PSV-DA and amniotic fluid volume as long as careful ultrasound monitoring is performed."8.12The effect of celecoxib for treatment of preterm labor on fetuses during the second trimester of pregnancy: A pilot case series. ( Chigusa, Y; Kawasaki, K; Kondoh, E; Mandai, M; Mogami, H; Ohtsuki, M; Ueda, A; Yamaguchi, K, 2022)
" The objective of the present study was to examine whether celecoxib, a selective COX-2 inhibitor, can reduce systemic LPS-induced brain inflammation and brain damage."7.79Celecoxib attenuates systemic lipopolysaccharide-induced brain inflammation and white matter injury in the neonatal rats. ( Bhatt, AJ; Cai, Z; Fan, LW; Kaizaki, A; Numazawa, S; Pang, Y; Tanaka, S; Tien, LT, 2013)
" Timing of administration, inadequate dosing and possible altered pharmacokinetics in pregnancy may explain the lack of efficacy."6.71The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section. ( Irwin, MG; Lee, LH; Lim, J; Wong, CK, 2004)
" Indomethacin was superior to celecoxib for pain score at rest at 8-12 h and celecoxib + parecoxib, diclofenac, and ketorolac for pain score on movement at 48 h."5.41Comparison of different nonsteroidal anti-inflammatory drugs for cesarean section: a systematic review and network meta-analysis. ( Blake, L; Carvalho, B; Carver, AL; Desai, N; Murdoch, I; O'Carroll, JE; Onwochei, DN; Sultan, P, 2023)
"To evaluate the effectiveness of celecoxib for pain relief and antipyresis during second trimester abortion using sublingual misoprostol."5.27Effectiveness of celecoxib for pain relief and antipyresis in second trimester medical abortions with misoprostol: a randomized controlled trial. ( Choobun, T; Tintara, H; Voradithi, P, 2018)
" Both celecoxib and valdecoxib are indicated for the treatment of primary dysmenorrhea, and may be effective in postoperative pain, including hysterectomy, and pain associated with endometriosis."4.81COX-2 inhibitors and their role in gynecology. ( Hayes, EC; Rock, JA, 2002)
"Celecoxib administration for more than 48 hours in the second trimester of pregnancy might be safe and tolerable in terms of fetal PSV-DA and amniotic fluid volume as long as careful ultrasound monitoring is performed."4.12The effect of celecoxib for treatment of preterm labor on fetuses during the second trimester of pregnancy: A pilot case series. ( Chigusa, Y; Kawasaki, K; Kondoh, E; Mandai, M; Mogami, H; Ohtsuki, M; Ueda, A; Yamaguchi, K, 2022)
" The objective of the present study was to examine whether celecoxib, a selective COX-2 inhibitor, can reduce systemic LPS-induced brain inflammation and brain damage."3.79Celecoxib attenuates systemic lipopolysaccharide-induced brain inflammation and white matter injury in the neonatal rats. ( Bhatt, AJ; Cai, Z; Fan, LW; Kaizaki, A; Numazawa, S; Pang, Y; Tanaka, S; Tien, LT, 2013)
" The objective of the current study was to examine whether celecoxib, a selective COX-2 inhibitor, could ameliorate lipopolysaccharide (LPS)-induced brain inflammation, dopaminergic neuronal dysfunction and sensorimotor behavioral impairments."3.79Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide. ( Bhatt, AJ; Cai, Z; Fan, LW; Kaizaki, A; Numazawa, S; Pang, Y; Tanaka, S; Tien, LT, 2013)
"To analyse the expression of 15 genes encoding receptors and enzymes associated with the molecular mechanism of the tocolytic drugs atosiban (oxytocin receptor antagonist), nifedipine (calcium channel blocker) and celecoxib (selective cyclo-oxygenase-2 inhibitor) in preterm labor patients with premature rupture of fetal membranes in relation to symptoms of intrauterine infection and preterm labor risk factors."3.78Expression of selected genes in preterm premature rupture of fetal membranes. ( Chyczewski, L; Kowalczuk, O; Kuć, P; Laudański, P; Laudański, T, 2012)
" Strikingly, uterine deletion of Trp53 increased the incidence of preterm birth, a condition that was corrected by oral administration of the selective COX2 inhibitor celecoxib."3.76Uterine-specific p53 deficiency confers premature uterine senescence and promotes preterm birth in mice. ( Bradshaw, HB; Daikoku, T; Dey, SK; Hirota, Y; Tranguch, S; Xie, H, 2010)
"To evaluate the molecular responses of vascular endothelial growth factor (VEGF) and its receptors to dexamethasone (Dex) and celecoxib (Cel) during hyperoxia and during hyperoxia followed by recovery in room air, in newborn rabbit retinas."3.71Regulation of retinal vascular endothelial growth factor and receptors in rabbits exposed to hyperoxia. ( Akmal, Y; Ang, JG; Beharry, KD; Modanlou, HD; Nishihara, KC; Ozaki, NK; Sheikh, R, 2002)
"We aimed to use celecoxib to suppress preterm labor instead magnesium sulfate (MgSO4) to prevent preterm labor."2.79Using celecoxib for the suppression of preterm labor instead of magnesium sulfate. ( Cheraghi, M; Moramezi, F; Saadati, N; Sokhray, L, 2014)
"Celecoxib was associated with a slightly lower VAS pain score at rest and less upper gastrointestinal symptoms were reported when compared to diclofenac."2.73Oral celecoxib versus oral diclofenac for post-perineal repair analgesia after spontaneous vaginal birth: a randomised trial. ( Lim, SS; Omar, SZ; Sockalingam, JK; Tan, PC, 2008)
" Timing of administration, inadequate dosing and possible altered pharmacokinetics in pregnancy may explain the lack of efficacy."2.71The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section. ( Irwin, MG; Lee, LH; Lim, J; Wong, CK, 2004)
" There were no significant maternal or neonatal adverse events."2.70A prospective randomized safety trial of celecoxib for treatment of preterm labor. ( Bernhard, LM; Gerber, S; Gross, GA; Leguizamon, G; Levy, R; Mathur, A; Nelson, DM; Sadovsky, Y; Stika, CS, 2002)
" RATIONALE FOR THE USE OF SELECTIVE COX-2 INHIBITORS: The rationale for the prescription of selective COX-2 inhibitors as neuroprotective drugs in AD lies on: Epidemiological data having shown a reduced risk of developing AD in patients treated with anti-inflammatory doses of classical NSAIDs (inhibition of COX-1 and COX-2) but not with antithrombotic doses of aspirin (selective inhibition of COX-1), Cellular experiments, Demonstration of a better gastro-intestinal (GI) safety profile with selective COX-2 inhibitors than with classical NSAIDs in short-term studies, allowing a possible long-term use in AD."2.41[Non-steroidal anti-inflammatory drugs with selectivity for cyclooxygenase-2 in Alzheimer's disease. Rationale and perspectives]. ( Blain, A; Blain, H; Jeandel, C; Jouzeau, JY; Netter, P; Terlain, B; Touchon, J; Tréchot, P, 2000)
" Celecoxib is metabolised primarily by the cytochrome P450 (CYP) 2C9 isoenzyme and has an elimination half-life of about 11 hours in healthy individuals."2.41Clinical pharmacokinetics and pharmacodynamics of celecoxib: a selective cyclo-oxygenase-2 inhibitor. ( Davies, NM; Day, RO; McLachlan, AJ; Williams, KM, 2000)
"· ERAS protocols improve postoperative pain control and lower postoperative opioid use."1.72Enhanced Recovery after Surgery Protocol to Improve Racial and Ethnic Disparities in Postcesarean Pain Management. ( Berghella, V; Cao, CD; Dayaratna, S; Felder, L; Konys, C; Mercier, R; Weerasooriya, N, 2022)
"Treatment with curcumin significantly could attenuate the celecoxib-induced deficits in proliferation through activating the Wnt/β-Catenin pathway."1.46Celecoxib-induced inhibition of neurogenesis in fetal frontal cortex is attenuated by curcumin via Wnt/β-catenin pathway. ( Liu, J; Sun, K; Tian, S; Wang, R; Wang, Y; Yang, X, 2017)
"Placentas from women with and without preeclampsia were collected."1.42Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1. ( Li, C; Raikwar, NS; Santillan, DA; Santillan, MK; Thomas, CP, 2015)
"Furthermore, breast cancer cells exposed to the involuting mammary microenvironment acquired prolymphangiogenic properties that contributed to peritumor lymphatic expansion, tumor size, invasion, and distant metastases."1.40Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer. ( Betts, CB; Borges, VF; Guo, Q; Jindal, S; Kapoor, P; Lyons, TR; Martinson, HA; Schedin, P, 2014)
"The prognosis of breast cancer in young women is influenced by reproductive history."1.37Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. ( Borges, VF; Conklin, MW; Eliceiri, KW; Keely, PJ; Lyons, TR; Marusyk, A; O'Brien, J; Schedin, P; Tan, AC, 2011)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.35)18.2507
2000's22 (47.83)29.6817
2010's14 (30.43)24.3611
2020's8 (17.39)2.80

Authors

AuthorsStudies
Felder, L1
Cao, CD1
Konys, C1
Weerasooriya, N1
Mercier, R1
Berghella, V1
Dayaratna, S1
Ohtsuki, M1
Chigusa, Y1
Mogami, H1
Ueda, A1
Kawasaki, K1
Yamaguchi, K1
Mandai, M1
Kondoh, E1
Zhao, Q1
Dai, W1
Chen, HY1
Jacobs, RE1
Zlokovic, BV1
Lund, BT1
Montagne, A1
Bonnin, A1
Ali, MA2
Abdelhady, SA2
Yacout, DM2
Kandil, LS2
Elblehi, SS1
El-Mas, MM2
Murdoch, I1
Carver, AL1
Sultan, P1
O'Carroll, JE1
Blake, L1
Carvalho, B1
Onwochei, DN1
Desai, N1
Essawy, MM1
Latif, D1
Darweesh, FF1
Osman, OM1
Abdelhakim, AM1
Nabil, H1
Ashour, ASA1
Yu, Y1
Gao, S1
Yuen, VM1
Choi, SW1
Xu, X2
Wang, R1
Tian, S1
Yang, X1
Liu, J1
Wang, Y1
Sun, K1
Tintara, H1
Voradithi, P1
Choobun, T1
Reijnders, D1
Liu, CC1
Zhao, AM1
Olson, KN1
Butler, SD1
Douglas, NC1
Sones, JL1
Fan, LW2
Kaizaki, A2
Tien, LT2
Pang, Y2
Tanaka, S2
Numazawa, S2
Bhatt, AJ2
Cai, Z2
Cha, J1
Bartos, A1
Egashira, M1
Haraguchi, H1
Saito-Fujita, T1
Leishman, E1
Bradshaw, H1
Dey, SK3
Hirota, Y2
Paech, MJ1
McDonnell, NJ1
Sinha, A1
Baber, C1
Nathan, EA1
Zavitsanou, K1
Lim, CK1
Purves-Tyson, T1
Karl, T1
Kassiou, M1
Banister, SD1
Guillemin, GJ1
Weickert, CS1
Lyons, TR2
Borges, VF2
Betts, CB1
Guo, Q1
Kapoor, P1
Martinson, HA1
Jindal, S1
Schedin, P2
Saadati, N1
Moramezi, F1
Cheraghi, M1
Sokhray, L1
Li, C1
Raikwar, NS1
Santillan, MK1
Santillan, DA1
Thomas, CP1
Daikoku, T1
Tranguch, S1
Xie, H1
Bradshaw, HB1
O'Brien, J1
Conklin, MW1
Keely, PJ1
Eliceiri, KW1
Marusyk, A1
Tan, AC1
Kuć, P1
Laudański, P1
Kowalczuk, O1
Chyczewski, L1
Laudański, T1
Stika, CS1
Gross, GA1
Leguizamon, G1
Gerber, S1
Levy, R1
Mathur, A1
Bernhard, LM1
Nelson, DM1
Sadovsky, Y1
Kajino, H1
Roman, C2
Clyman, RI2
Hayes, EC1
Rock, JA1
Hausman, N4
Beharry, K2
Nishihara, K2
Akmal, Y4
Asrat, T4
Beharry, KD3
Nishihara, KC2
Stavitsky, Y2
Shafiq, N1
Malhotra, S1
Pandhi, P1
Kammerer, S1
Chan, VS1
Lee, LH1
Irwin, MG1
Lim, J1
Wong, CK1
Hartleroad, JY1
Modanlou, HD2
Borna, S1
Saeidi, FM1
Lim, SS1
Tan, PC1
Sockalingam, JK1
Omar, SZ1
Rodgers, E1
Blain, H1
Jouzeau, JY1
Blain, A1
Terlain, B1
Tréchot, P1
Touchon, J1
Netter, P1
Jeandel, C1
Davies, NM1
McLachlan, AJ1
Day, RO1
Williams, KM1
Jeske, AH1
Takahashi, Y1
Chemtob, S1
Tse, MM1
Lin, E1
Heymann, MA1
Sakai, M1
Tanebe, K1
Sasaki, Y1
Momma, K1
Yoneda, S1
Saito, S1
Reese, J1
Zhao, X1
Ma, WG1
Brown, N1
Maziasz, TJ1
Slattery, MM1
Friel, AM1
Healy, DG1
Morrison, JJ1
Ozaki, NK1
Ang, JG1
Sheikh, R1
Sookvanichsilp, N1
Pulbutr, P1

Reviews

7 reviews available for celecoxib and Pregnancy

ArticleYear
Comparison of different nonsteroidal anti-inflammatory drugs for cesarean section: a systematic review and network meta-analysis.
    Korean journal of anesthesiology, 2023, Volume: 76, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cesarean Section; Diclofenac; Female; Humans; In

2023
COX-2 inhibitors and their role in gynecology.
    Obstetrical & gynecological survey, 2002, Volume: 57, Issue:11

    Topics: Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Administra

2002
A mechanistic perspective on the specificity and extent of COX-2 inhibition in pregnancy.
    Drug safety, 2004, Volume: 27, Issue:7

    Topics: Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etoricoxib; Fem

2004
Treating pain with COX-2 inhibitors.
    The Nurse practitioner, 1999, Volume: 24, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Drug Costs; Drug Inte

1999
[Non-steroidal anti-inflammatory drugs with selectivity for cyclooxygenase-2 in Alzheimer's disease. Rationale and perspectives].
    Presse medicale (Paris, France : 1983), 2000, Feb-12, Volume: 29, Issue:5

    Topics: Adult; Age Factors; Aged; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain

2000
Clinical pharmacokinetics and pharmacodynamics of celecoxib: a selective cyclo-oxygenase-2 inhibitor.
    Clinical pharmacokinetics, 2000, Volume: 38, Issue:3

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Biotransform

2000
COX-2 inhibitors and dental pain control.
    The Journal of the Greater Houston Dental Society, 1999, Volume: 71, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Contraindications; Cyclooxygenase Inhibitors; Fa

1999

Trials

10 trials available for celecoxib and Pregnancy

ArticleYear
Oral tramadol versus oral celecoxib for analgesia after mediolateral episiotomy repair in obese primigravidae: a randomized controlled trial.
    International urogynecology journal, 2021, Volume: 32, Issue:9

    Topics: Analgesia; Analgesics, Opioid; Celecoxib; Double-Blind Method; Episiotomy; Female; Humans; Obesity;

2021
The analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block combined with oral multimodal analgesia in comparison with oral multimodal analgesia after caesarean delivery: a randomized controlled trial.
    BMC anesthesiology, 2021, 01-07, Volume: 21, Issue:1

    Topics: Abdominal Muscles; Acetaminophen; Administration, Oral; Adult; Analgesia, Obstetrical; Analgesics; C

2021
Effectiveness of celecoxib for pain relief and antipyresis in second trimester medical abortions with misoprostol: a randomized controlled trial.
    Archives of gynecology and obstetrics, 2018, Volume: 297, Issue:3

    Topics: Abortion, Therapeutic; Administration, Sublingual; Adult; Anti-Inflammatory Agents, Non-Steroidal; A

2018
A randomised controlled trial of parecoxib, celecoxib and paracetamol as adjuncts to patient-controlled epidural analgesia after caesarean delivery.
    Anaesthesia and intensive care, 2014, Volume: 42, Issue:1

    Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; An

2014
Using celecoxib for the suppression of preterm labor instead of magnesium sulfate.
    Journal of pregnancy, 2014, Volume: 2014

    Topics: Adult; Celecoxib; Female; Gestational Age; Humans; Magnesium Sulfate; Obstetric Labor, Premature; Pa

2014
A prospective randomized safety trial of celecoxib for treatment of preterm labor.
    American journal of obstetrics and gynecology, 2002, Volume: 187, Issue:3

    Topics: Adolescent; Adult; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Indome

2002
The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section.
    Anaesthesia, 2004, Volume: 59, Issue:9

    Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Antipruritics; Celecoxib; Ce

2004
Celecoxib versus magnesium sulfate to arrest preterm labor: randomized trial.
    The journal of obstetrics and gynaecology research, 2007, Volume: 33, Issue:5

    Topics: Adult; Birth Weight; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Gestational Age; Humans; Infant

2007
Oral celecoxib versus oral diclofenac for post-perineal repair analgesia after spontaneous vaginal birth: a randomised trial.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2008, Volume: 48, Issue:1

    Topics: Administration, Oral; Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Delivery

2008
Uterine relaxant effects of cyclooxygenase-2 inhibitors in vitro.
    Obstetrics and gynecology, 2001, Volume: 98, Issue:4

    Topics: Adult; Celecoxib; Cesarean Section; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase In

2001

Other Studies

29 other studies available for celecoxib and Pregnancy

ArticleYear
Enhanced Recovery after Surgery Protocol to Improve Racial and Ethnic Disparities in Postcesarean Pain Management.
    American journal of perinatology, 2022, Volume: 39, Issue:13

    Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Celecoxib; Endrin; Enhanced

2022
The effect of celecoxib for treatment of preterm labor on fetuses during the second trimester of pregnancy: A pilot case series.
    Taiwanese journal of obstetrics & gynecology, 2022, Volume: 61, Issue:2

    Topics: Celecoxib; Cyclooxygenase 2 Inhibitors; Ductus Arteriosus; Female; Humans; Infant; Infant, Newborn;

2022
Prenatal disruption of blood-brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation.
    Proceedings of the National Academy of Sciences of the United States of America, 2022, 04-12, Volume: 119, Issue:15

    Topics: Animals; Blood-Brain Barrier; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Encephalitis

2022
Gestational NSAIDs distinctly reprogram cardiac injury in preeclamptic rats: Roles of cyclooxygenase, apoptotic and autophagic trails.
    Life sciences, 2022, Dec-01, Volume: 310

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhi

2022
The suppression of MAPK/NOX/MMP signaling prompts renoprotection conferred by prenatal naproxen in weaning preeclamptic rats.
    Scientific reports, 2023, 10-15, Volume: 13, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Diclofenac; Female; Humans; Naproxen; P

2023
Celecoxib-induced inhibition of neurogenesis in fetal frontal cortex is attenuated by curcumin via Wnt/β-catenin pathway.
    Life sciences, 2017, Sep-15, Volume: 185

    Topics: Animals; Animals, Newborn; Brain; Celecoxib; Cell Differentiation; Cell Proliferation; Cells, Cultur

2017
Celecoxib restores angiogenic factor expression at the maternal-fetal interface in the BPH/5 mouse model of preeclampsia.
    Physiological genomics, 2018, 05-01, Volume: 50, Issue:5

    Topics: Angiogenesis Inducing Agents; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease Models, Anima

2018
Celecoxib attenuates systemic lipopolysaccharide-induced brain inflammation and white matter injury in the neonatal rats.
    Neuroscience, 2013, Jun-14, Volume: 240

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Calcium-Binding Proteins; Celecoxib; Cell Death; Cycl

2013
Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide.
    Journal of neuroinflammation, 2013, Apr-05, Volume: 10

    Topics: Animals; Animals, Newborn; Blotting, Western; Celecoxib; Cyclooxygenase 2 Inhibitors; Dopaminergic N

2013
Combinatory approaches prevent preterm birth profoundly exacerbated by gene-environment interactions.
    The Journal of clinical investigation, 2013, Volume: 123, Issue:9

    Topics: 20-Hydroxysteroid Dehydrogenases; Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors;

2013
Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: amelioration by COX-2 inhibition.
    Brain, behavior, and immunity, 2014, Volume: 41

    Topics: Animals; Brain; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dizocilpine Maleate;

2014
Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:9

    Topics: Animals; Breast Neoplasms; Celecoxib; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Female

2014
Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1.
    Placenta, 2015, Volume: 36, Issue:4

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cell Hypoxia; Cell Line

2015
Uterine-specific p53 deficiency confers premature uterine senescence and promotes preterm birth in mice.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:3

    Topics: Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Decidua; Dinoprost; Embryo Implan

2010
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2.
    Nature medicine, 2011, Aug-07, Volume: 17, Issue:9

    Topics: Analysis of Variance; Animals; Blotting, Western; Breast Neoplasms; Carcinoma, Ductal; Celecoxib; Ce

2011
Expression of selected genes in preterm premature rupture of fetal membranes.
    Acta obstetricia et gynecologica Scandinavica, 2012, Volume: 91, Issue:8

    Topics: Adult; Calcium Channel Blockers; Calcium Channels, L-Type; Celecoxib; Cyclooxygenase 2 Inhibitors; D

2012
Renal effects of cyclooxygenase-2 inhibition in fetal lambs.
    Biology of the neonate, 2002, Volume: 82, Issue:4

    Topics: Animals; Arteries; Body Water; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygen

2002
Antenatal administration of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, appears to improve placental perfusion in the pregnant rabbit.
    Prostaglandins & other lipid mediators, 2003, Volume: 70, Issue:3-4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Body Weight; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 In

2003
Effect of the antenatal administration of celecoxib during the second and third trimesters of pregnancy on prostaglandin, cytokine, and nitric oxide levels in rabbits.
    American journal of obstetrics and gynecology, 2003, Volume: 189, Issue:6

    Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Cytokines; Drug Administration Schedule; Female; Mode

2003
Response of fetal prostanoids, nitric oxide, and ductus arteriosus to the short- and long-term antenatal administration of celecoxib, a selective cyclo-oxygenase-2 inhibitor, in the pregnant rabbit.
    American journal of obstetrics and gynecology, 2003, Volume: 189, Issue:6

    Topics: Analysis of Variance; Animals; Celecoxib; Cyclooxygenase Inhibitors; Drug Administration Schedule; D

2003
Comparison of nonselective cyclo-oxygenase (COX) inhibitor and selective COX-2 inhibitors on preimplantation loss, postimplantation loss and duration of gestation: an experimental study.
    Contraception, 2004, Volume: 69, Issue:1

    Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Embryonic Development; Female; Gestational Age; Indom

2004
[New prevention strategies against breast cancer and cervical carcinoma. What can you advice to your patients].
    MMW Fortschritte der Medizin, 2003, Dec-11, Volume: 145, Issue:50

    Topics: Adolescent; Adult; Age Factors; Anastrozole; Anticarcinogenic Agents; Breast Neoplasms; Celecoxib; C

2003
Effect of maternal administration of selective cyclooxygenase (COX)-2 inhibitors on renal size, growth factors, proteinases, and COX-2 secretion in the fetal rabbit.
    Biology of the neonate, 2005, Volume: 87, Issue:4

    Topics: Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female

2005
Cyclooxygenase-2 inhibitors constrict the fetal lamb ductus arteriosus both in vitro and in vivo.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase

2000
Evaluation of the tocolytic effect of a selective cyclooxygenase-2 inhibitor in a mouse model of lipopolysaccharide-induced preterm delivery.
    Molecular human reproduction, 2001, Volume: 7, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chorioamnionitis; Cyclooxygenase 2; Cyc

2001
Comparative analysis of pharmacologic and/or genetic disruption of cyclooxygenase-1 and cyclooxygenase-2 function in female reproduction in mice.
    Endocrinology, 2001, Volume: 142, Issue:7

    Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase

2001
Cutaneous drug reaction case reports: from the world literature.
    American journal of clinical dermatology, 2002, Volume: 3, Issue:1

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Bupropion; Celecoxib; Chlorquinaldol; Cytarabi

2002
Regulation of retinal vascular endothelial growth factor and receptors in rabbits exposed to hyperoxia.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:5

    Topics: Animals; Animals, Newborn; Celecoxib; Cyclooxygenase Inhibitors; Dexamethasone; Endothelial Growth F

2002
Anti-implantation effects of indomethacin and celecoxib in rats.
    Contraception, 2002, Volume: 65, Issue:5

    Topics: Animals; Celecoxib; Contraception; Contraceptives, Postcoital; Cyclooxygenase Inhibitors; Decidua; E

2002