celecoxib and Peutz-Jeghers Syndrome studies

celecoxib and Peutz-Jeghers Syndrome

Peutz-Jeghers Syndrome: A hereditary disease caused by autosomal dominant mutations involving CHROMOSOME 19. It is characterized by the presence of INTESTINAL POLYPS, consistently in the JEJUNUM, and mucocutaneous pigmentation with MELANIN spots of the lips, buccal MUCOSA, and digits.

Research Excerpts

Excerpt	Relevance	Reference
"Celecoxib was much less efficient in reducing tumourigenesis in MNU-treated mice (by 23%; 1686 mm(3)) than in untreated mice (76%; 58 mm(3))."	1.39	N-methylnitrosourea aggravates gastrointestinal polyposis in Lkb1+/- mice. ( Gao, Y; Mäkelä, TP; Ristimäki, AP; Udd, L, 2013)
"Celecoxib treatment initiating before polyposis (3."	1.32	Suppression of Peutz-Jeghers polyposis by inhibition of cyclooxygenase-2. ( Järvinen, HJ; Katajisto, P; Lahesmaa, AM; Lepistö, A; Mäkelä, TP; Ristimäki, AP; Rossi, DJ; Udd, L; Ylikorkala, A, 2004)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	2 (66.67)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

1 (33.33)

29.6817

2010's

2 (66.67)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Udd, L	2
Gao, Y	1
Ristimäki, AP	2
Mäkelä, TP	2
Thakkar, K	1
Fishman, DS	1
Gilger, MA	1
Katajisto, P	1
Rossi, DJ	1
Lepistö, A	1
Lahesmaa, AM	1
Ylikorkala, A	1
Järvinen, HJ	1

Studies

Udd, L

Gao, Y

Ristimäki, AP

Mäkelä, TP

Thakkar, K

Fishman, DS

Gilger, MA

Katajisto, P

Rossi, DJ

Lepistö, A

Lahesmaa, AM

Ylikorkala, A

Järvinen, HJ

Reviews

1 review available for celecoxib and Peutz-Jeghers Syndrome

Article	Year
Colorectal polyps in childhood. Current opinion in pediatrics, 2012, Volume: 24, Issue:5 Topics: Adenomatous Polyps; Adolescent; Age of Onset; Celecoxib; Child; Child, Preschool; Colonic Polyps; Co	2012

Article

Year

Colorectal polyps in childhood.

Current opinion in pediatrics, 2012, Volume: 24, Issue:5

Topics: Adenomatous Polyps; Adolescent; Age of Onset; Celecoxib; Child; Child, Preschool; Colonic Polyps; Co

2012

Other Studies

2 other studies available for celecoxib and Peutz-Jeghers Syndrome

Article	Year
N-methylnitrosourea aggravates gastrointestinal polyposis in Lkb1+/- mice. Carcinogenesis, 2013, Volume: 34, Issue:10 Topics: AMP-Activated Protein Kinases; Animals; Carcinogenesis; Carcinogens; Celecoxib; Cyclooxygenase 2 Inh	2013
Suppression of Peutz-Jeghers polyposis by inhibition of cyclooxygenase-2. Gastroenterology, 2004, Volume: 127, Issue:4 Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cele	2004

Article

Year

N-methylnitrosourea aggravates gastrointestinal polyposis in Lkb1+/- mice.

Carcinogenesis, 2013, Volume: 34, Issue:10

Topics: AMP-Activated Protein Kinases; Animals; Carcinogenesis; Carcinogens; Celecoxib; Cyclooxygenase 2 Inh

2013

Suppression of Peutz-Jeghers polyposis by inhibition of cyclooxygenase-2.

Gastroenterology, 2004, Volume: 127, Issue:4

Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cele

2004