celecoxib has been researched along with Pain, Postoperative in 192 studies
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy and safety of preemptive analgesia with a transversus abdominis plane (TAP) block versus celecoxib for patients undergoing laparoscopic transabdominal preperitoneal inguinal hernia repair (LTAPP)." | 9.41 | Efficacy of celecoxib as preemptive analgesia for patients undergoing laparoscopic inguinal hernia repair: a randomized trial. ( Fukami, Y; Hashimoto, A; Iwamoto, S; Kaneko, K; Komatsu, S; Kurahashi, S; Mishima, H; Murotani, K; Saito, T; Sano, T, 2021) |
| "To evaluate the effectiveness of celecoxib for pain relief and antipyresis during second trimester abortion using sublingual misoprostol." | 9.27 | Effectiveness of celecoxib for pain relief and antipyresis in second trimester medical abortions with misoprostol: a randomized controlled trial. ( Choobun, T; Tintara, H; Voradithi, P, 2018) |
| " Pain at rest/motion (based on pain visual analog scale (VAS) score), rescue analgesia consumption, satisfaction level and adverse events were assessed after AKS." | 7.01 | Oxycodone-paracetamol tablet exhibits increased analgesic efficacy for acute postoperative pain, higher satisfaction and comparable safety profiles compared with celecoxib in patients underwent arthroscopic knee surgery. ( Di, J; Liu, J; Xing, E; Zhang, Y, 2021) |
| "Standard dosing of the cyclooxygenase-2 inhibitor celecoxib slightly reduced perioperative cyclooxygenase activity during cancer surgery." | 6.84 | Impact of celecoxib on inflammation during cancer surgery: a randomized clinical trial. ( Hiller, JG; Ho, KM; Kuruvilla, N; Millen, R; Ramsay, R; Riedel, B; Sampurno, S, 2017) |
| " The hypothesis is that compared to placebo with opioids as rescue treatment, sequential use of parecoxib and celecoxib can achieve less morphine consumption over the postoperative 2 weeks, as well as better pain control, quicker functional recovery in the postoperative 6 weeks and less opioid-related adverse events during the 12-week recovery phase." | 6.82 | Efficacy and safety of Postoperative Intravenous Parecoxib sodium Followed by ORal CElecoxib (PIPFORCE) post-total knee arthroplasty in patients with osteoarthritis: a study protocol for a multicentre, double-blind, parallel-group trial. ( Bian, Y; Feng, B; Jiang, J; Lin, J; Pei, F; Shen, B; Sun, T; Wang, W; Weng, X; Yan, S; Zhang, M; Zhuang, Q, 2016) |
| " Timing of administration, inadequate dosing and possible altered pharmacokinetics in pregnancy may explain the lack of efficacy." | 6.71 | The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section. ( Irwin, MG; Lee, LH; Lim, J; Wong, CK, 2004) |
| "Celecoxib is a selective cyclo-oxygenase-2 (COX-2) inhibitor usually prescribed for the relief of chronic pain in osteoarthritis and rheumatoid arthritis." | 6.49 | Single dose oral celecoxib for acute postoperative pain in adults. ( Derry, S; Moore, RA, 2013) |
| "Celecoxib is a selective cyclo-oxygenase-2 (COX-2) inhibitor usually prescribed for the relief of chronic pain in osteoarthritis and rheumatoid arthritis." | 6.48 | Single dose oral celecoxib for acute postoperative pain in adults. ( Derry, S; Moore, RA, 2012) |
| "Celecoxib is a selective cyclo-oxygenase-2 (COX-2) inhibitor prescribed for the relief of chronic pain in osteoarthritis and rheumatoid arthritis." | 6.44 | Single dose oral celecoxib for acute postoperative pain in adults. ( Barden, J; Derry, S; McQuay, HJ; Moore, RA, 2008) |
| "The preemptive analgesia regimen of pregabalin combined with celecoxib had positive effects on improving acute pain and reducing the cumulative dose of opioids after TKA." | 5.69 | Positive Preemptive Analgesia Effectiveness of Pregabalin Combined with Celecoxib in Total Knee Arthroplasty: A Prospective Controlled Randomized Study. ( Ding, C; Liu, X; Xiang, B; Yan, L; Zhou, Y, 2023) |
| "Celecoxib is a selective COX-2 inhibitor and has a lower effect of platelet aggregation compared with conventional non-steroidal anti-inflammatory drugs (NSAIDs)." | 5.43 | A Comparison of Analgesic Effect between Loxoprofen and Celecoxib and the Frequency of the Hemorrhage Following Tonsillectomy. ( Ariki, M; Fukushima, N; Hirai, T; Miyahara, N; Yoshiga, A, 2016) |
| "To investigate the efficacy and safety of preemptive analgesia with a transversus abdominis plane (TAP) block versus celecoxib for patients undergoing laparoscopic transabdominal preperitoneal inguinal hernia repair (LTAPP)." | 5.41 | Efficacy of celecoxib as preemptive analgesia for patients undergoing laparoscopic inguinal hernia repair: a randomized trial. ( Fukami, Y; Hashimoto, A; Iwamoto, S; Kaneko, K; Komatsu, S; Kurahashi, S; Mishima, H; Murotani, K; Saito, T; Sano, T, 2021) |
| "To evaluate the effectiveness of celecoxib for pain relief and antipyresis during second trimester abortion using sublingual misoprostol." | 5.27 | Effectiveness of celecoxib for pain relief and antipyresis in second trimester medical abortions with misoprostol: a randomized controlled trial. ( Choobun, T; Tintara, H; Voradithi, P, 2018) |
| "05) between the four groups in terms of outcomes such as rest pain, movement pain, postoperative fentanyl requirements, or changes in anxiety scores." | 5.22 | The effect of pregabalin and celecoxib on the analgesic requirements after laparoscopic cholecystectomy: a randomized controlled trial. ( Barnett, AG; Fraser, JF; Gurunathan, U; King, G; Rapchuk, IL, 2016) |
| "To determine whether prostaglandin inhibition by cyclooxygenase inhibitors, celecoxib or diclofenac, could enhance gastrointestinal recovery and reduce post-operative ileus in humans." | 5.14 | Clinical trial: the impact of cyclooxygenase inhibitors on gastrointestinal recovery after major surgery - a randomized double blind controlled trial of celecoxib or diclofenac vs. placebo. ( Bampton, PA; Costa, M; De Fontgalland, D; Leach, PL; McLaughlin, K; Wattchow, DA, 2009) |
| "Studies published during the past 12 months have provided results for several 'take home messages', which include use of perioperative celecoxib improves short-term and long-term postoperative outcome; perineural catheter analgesia is feasible and safe at home; small incision cholecystectomy is quicker to perform and has no disadvantages when compared with laparoscopic technique; 2-chloroprocaine appears to be the drug of choice for spinal anesthesia; simple regional anesthesia techniques such as wound infiltration and intraarticular local anesthetics are safe and effective; Society of Ambulatory Anesthesia guidelines for managing postoperative nausea and vomiting recommend use of regional anesthesia techniques and use of certain drugs (and avoidance of others) if general anesthesia is chosen." | 4.84 | Postdischarge complications and rehabilitation after ambulatory surgery. ( Rawal, N, 2008) |
| "Celecoxib (CXB) has a good analgesic effect on postoperative acute pain, but clinically its compliance is compromised because of frequent administration." | 4.31 | Comparison of in vivo behaviors of intramuscularly long-acting celecoxib nanosuspensions with different particle sizes for the postoperative pain treatment. ( Fu, Q; He, Z; Li, M; Qin, M; Sui, X; Sun, Y; Xin, J; Ye, G, 2023) |
| " The protocol utilized oral celecoxib and scheduled oral acetaminophen for pain control, with opioids used only as needed for breakthrough pain." | 3.91 | Multimodal Postoperative Pain Control Is Effective and Reduces Opioid Use After Laparoscopic Roux-en-Y Gastric Bypass. ( Dove, J; Fluck, M; Gabrielsen, JD; Gionfriddo, MR; Horsley, RD; McField, DAP; Medico, C; Parker, DM; Petrick, AT; Vogels, ED, 2019) |
| "116 consecutive patients scheduled for breast cancer surgery were prospectively scored according to pain, PONV and sedation after being introduced to a combined evidence-based, empiric multimodal opioid-sparing prevention and treatment regime consisting of Paracetamol, Celecoxib, Dextromethorphan, Gabapetin, Dexamethason and Ondansetron." | 3.74 | [Multimodal treatment of pain and nausea in breast cancer surgery]. ( Callesen, T; Gärtner, R; Kehlet, H; Kroman, N, 2008) |
| " Besides, the incidences of all adverse events were not different between imrecoxib and celecoxib groups (all P > 0." | 3.30 | Postoperative analgesic efficacy and safety of imrecoxib versus celecoxib in hip osteoarthritis patients undergoing total hip arthroplasty: a multi-center, randomized, controlled, non-inferiority study. ( Cui, S; Jiang, L; Liu, Z; Miao, X; Wang, Z; Zhang, K, 2023) |
| " This open-label study (NCT03974932) evaluated the efficacy and safety of HTX-011 combined with an MMA regimen in patients undergoing TKA under spinal anesthesia." | 3.30 | HTX-011 in Combination with Multimodal Analgesic Regimen Minimized Severe Pain and Opioid Use after Total Knee Arthroplasty in an Open-Label Study. ( Berkowitz, R; Hacker, S; Hu, J; Lee, GC; Rechter, A, 2023) |
| "The acetaminophen group was administered celecoxib at 400 mg, pregabalin at 150 mg, and acetaminophen at 300 mg 2 h before TKA." | 3.30 | Efficacy of Adding Acetaminophen to Preemptive Multimodal Analgesia in Total Knee Arthroplasty: A Double-blinded Randomized Study. ( Kang, P; Ma, T; Wang, L; Wang, Q; Zhao, C, 2023) |
| " The pain visual analog scale (VAS) score at rest or flexion, salvage consumption of pethidine, patient's satisfaction score, modified University of California at Los Angeles (UCLA) score and adverse events were evaluated." | 3.11 | The analgesic effect and safety of preoperative versus postoperative administration of celecoxib in patients who underwent arthroscopic rotator cuff repair: a randomized, controlled study. ( Liu, L; Shao, Y; Wang, J; Wang, S; Yang, J, 2022) |
| "Imrecoxib is a novel cyclooxygenase-2 inhibitor independently developed in China, which exhibits a good efficacy and tolerance in orthopedic disorders." | 3.11 | Imrecoxib versus celecoxib as postoperative analgesia for patients receiving arthroscopic knee surgery: a randomized, controlled, non-inferiority study. ( Guo, W; Li, J; Liu, Y, 2022) |
| " Although superiority to tramadol was not reached, CTC 200 mg BID exposed patients to lower cumulative opioid (tramadol) doses than tramadol (100 mg QID) alone, with fewer treatment-emergent adverse events." | 3.11 | Efficacy and safety of co-crystal of tramadol-celecoxib (CTC) in acute moderate-to-severe pain after abdominal hysterectomy: A randomized, double-blind, phase 3 trial (STARDOM2). ( Adeyemi, S; But-Husaim, L; Cebrecos, J; Fettiplace, J; Gascón, N; Langford, R; Morte, A; Ortiz, E; Plata-Salamán, C; Raba, G; Sust, M; Vaqué, A, 2022) |
| " DFN-15 was similar to placebo in the incidence of adverse events with no apparent dose-related effects." | 3.11 | Efficacy and safety of single-dose DFN-15 for treatment of acute postsurgical dental pain: a randomized, double-blind, placebo-controlled study. ( Bertoch, T; Munjal, S; Shenoy, S; Singla, N, 2022) |
| " As for adverse events, the incidences of nausea, vomiting, constipation, drowsiness and dizziness were similar between PRE group and POST group." | 3.01 | Efficiency and safety: comparison between preoperative analgesia and postoperative analgesia using non-steroidal anti-inflammatory drugs in patients receiving arthroscopic knee surgery in a multicenter, randomized, controlled study. ( Jiang, C; Ma, L; Wang, H; Zhang, L, 2021) |
| " Pain at rest/motion (based on pain visual analog scale (VAS) score), rescue analgesia consumption, satisfaction level and adverse events were assessed after AKS." | 3.01 | Oxycodone-paracetamol tablet exhibits increased analgesic efficacy for acute postoperative pain, higher satisfaction and comparable safety profiles compared with celecoxib in patients underwent arthroscopic knee surgery. ( Di, J; Liu, J; Xing, E; Zhang, Y, 2021) |
| "The primary endpoint was postoperative pain and adverse events, and the secondary endpoint was the length of the analgesic procedure and physiological function on postoperative day 1." | 2.94 | Intercostal block vs. epidural analgesia in thoracoscopic lung cancer surgery: a randomized trial. ( Hamano, K; Hayashi, M; Murakami, J; Tanaka, T; Ueda, K; Utada, K, 2020) |
| "The primary outcome variable was postoperative pain measured on a visual analog scale at different time points." | 2.94 | Comparison of Low Pre-Emptive Oral Doses of Celecoxib Versus Acetaminophen for Postoperative Pain Management After Third Molar Surgery: A Randomized Controlled Study. ( Li, Z; Lv, K; Xie, L; Yang, RT; Zhou, HH, 2020) |
| "The primary outcome chosen was postoperative pain, which was evaluated using the visual analogue scale (VAS) score recorded by each patient." | 2.90 | Evaluation of the efficacy of celecoxib and ibuprofen on postoperative pain, swelling, and mouth opening after surgical removal of impacted third molars: a randomized, controlled clinical trial. ( Cicciù, M; Isola, G; Matarese, G; Matarese, M; Ramaglia, L, 2019) |
| "Celecoxib was the most effective analgesic of the three studied drugs in controlling postoperative pain after mandibular third molar extraction in our subjects." | 2.87 | Comparative Analgesic Effects of Ibuprofen, Celecoxib and Tramadol after third Molar Surgery: A Randomized Double Blind Controlled Trial. ( Akinbade, AO; Ndukwe, KC; Owotade, FJ, 2018) |
| "Compare postoperative pain scores following hysterectomy in patients receiving perioperative celecoxib versus postoperative ketorolac as part of a multimodal pain regimen." | 2.87 | Celecoxib versus ketorolac following robotic hysterectomy for the management of postoperative pain: An open-label randomized control trial. ( ElNaggar, AC; Tillmanns, TD; Ulm, MA, 2018) |
| "Standard dosing of the cyclooxygenase-2 inhibitor celecoxib slightly reduced perioperative cyclooxygenase activity during cancer surgery." | 2.84 | Impact of celecoxib on inflammation during cancer surgery: a randomized clinical trial. ( Hiller, JG; Ho, KM; Kuruvilla, N; Millen, R; Ramsay, R; Riedel, B; Sampurno, S, 2017) |
| "The celecoxib-treated group experienced significantly more vomiting (celecoxib vs placebo p < 0." | 2.84 | Is celecoxib a useful adjunct in the treatment of post-tonsillectomy pain in the adult population? A randomised, double-blind, placebo-controlled study. ( De Silva, N; Diamantaras, D; Mahanta, V; Ng, TT; Priestley, J; Redman, J, 2017) |
| " Pain visual analog scale (VAS) scores (at rest and at 90 flexion) and patient global assessment (PGA) score were evaluated before and after operation, and also pethidine consumption and adverse events (AEs)." | 2.84 | The efficacy and safety of early initiation of preoperative analgesia with celecoxib in patients underwent arthroscopic knee surgery: A randomized, controlled study. ( Du, Y; Huang, W; Shan, J; Xu, G; Zhou, F, 2017) |
| "Celecoxib is a cyclooxygenase-2-specific inhibitor indicated to treat acute pain and pain secondary to osteoarthritis and rheumatoid arthritis." | 2.82 | Celecoxib Versus Placebo in Tonsillectomy: A Prospective, Randomized, Double-Blind Placebo-Controlled Trial. ( Bodeker, KL; Trask, DK; Van Daele, DJ, 2016) |
| "To assess hyperalgesia in persistent pain patients we performed an additional analysis on patients reporting VAS>30 at 12 months." | 2.82 | Hyperalgesia and Persistent Pain after Breast Cancer Surgery: A Prospective Randomized Controlled Trial with Perioperative COX-2 Inhibition. ( Filippini-de Moor, GP; Steegers, MA; van Helmond, N; Vissers, KC; Wilder-Smith, OH, 2016) |
| " The hypothesis is that compared to placebo with opioids as rescue treatment, sequential use of parecoxib and celecoxib can achieve less morphine consumption over the postoperative 2 weeks, as well as better pain control, quicker functional recovery in the postoperative 6 weeks and less opioid-related adverse events during the 12-week recovery phase." | 2.82 | Efficacy and safety of Postoperative Intravenous Parecoxib sodium Followed by ORal CElecoxib (PIPFORCE) post-total knee arthroplasty in patients with osteoarthritis: a study protocol for a multicentre, double-blind, parallel-group trial. ( Bian, Y; Feng, B; Jiang, J; Lin, J; Pei, F; Shen, B; Sun, T; Wang, W; Weng, X; Yan, S; Zhang, M; Zhuang, Q, 2016) |
| "The aim of this meta-analysis was to assess the analgesic efficacy and adverse effects of celecoxib compared to non-opioid drugs after third molar surgery." | 2.82 | Analgesic effectiveness and safety of celecoxib versus non-opioid active controls after third molar surgery: A meta-analytical evaluation. ( Alonso-Castro, ÁJ; Franco-de la Torre, L; Franco-González, MA; Isiordia-Espinoza, MA, 2022) |
| "Celecoxib is an effective analgesic in adult surgery patients; however, its analgesic efficacy on pain and functional recovery in pediatric A&T patients is unknown." | 2.80 | Celecoxib pharmacogenetics and pediatric adenotonsillectomy: a double-blinded randomized controlled study. ( Aglipay, M; Lamontagne, C; MacCormick, J; McFaul, C; Murto, K; Ramakko, KA; Rosen, D; Vaillancourt, R, 2015) |
| "Celecoxib was discontinued in one patient on day 2 at the patient's request." | 2.80 | Loxoprofen sodium and celecoxib for postoperative pain in patients after spinal surgery: a randomized comparative study. ( Imura, T; Inoue, G; Miyagi, M; Nakazawa, T; Saito, W; Sekiguchi, H; Takahira, N; Takaso, M; Uchida, K, 2015) |
| "Patient postoperative pain levels were determined using the visual analog pain scale and were documented at 0, 4, 8, 12, 16, 24, and 36 hours postoperative." | 2.78 | A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study. ( Bohlman, HH; Cassinelli, EH; Furey, CG; Garcia, RM; Messerschmitt, PJ, 2013) |
| " The incidence of treatment-related, all-cause adverse events was slightly lower in patients receiving celecoxib 200 mg (20." | 2.77 | Efficacy and safety of additional 200-mg dose of celecoxib in adult patients with postoperative pain following extraction of impacted third mandibular molar: a multicenter, randomized, double-blind, placebo-controlled, phase II study in Japan. ( Kaneko, A; Machii, K; Ohkura, M; Ohta, H; Saito, K; Suzuki, M, 2012) |
| "Celecoxib treatment was not statistically different than placebo for these latter two parameters." | 2.77 | A phase 2 study evaluating the efficacy and safety of a novel, proprietary, nano-formulated, lower dose oral diclofenac. ( Daniels, S; Gibofsky, A; Manvelian, G, 2012) |
| "Recovery times, postoperative pain scores, and the need for rescue analgesics were recorded before discharge." | 2.76 | The effects of oral ibuprofen and celecoxib in preventing pain, improving recovery outcomes and patient satisfaction after ambulatory surgery. ( Fermelia, DE; Kariger, R; Naruse, R; Sloninsky, A; Tang, J; Time, M; Tsushima, GK; Webb, T; Wender, RH; White, PF; Yumul, R; Zaentz, A; Zhao, M, 2011) |
| "Postoperative pain is an adverse effect of periodontal surgeries and may therefore be prevented or minimized." | 2.76 | The use of etoricoxib and celecoxib for pain prevention after periodontal surgery: a double-masked, parallel-group, placebo-controlled, randomized clinical trial. ( Pilatti, GL; Santos, FA; Steffens, JP, 2011) |
| "Of 200 consecutive breast cancer patients, 191 received the full package." | 2.75 | Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. ( Callesen, T; Gärtner, R; Kehlet, H; Kroman, N, 2010) |
| " We investigated the potential benefits of oral celecoxib on postoperative analgesia combined with thoracic epidural analgesia (TEA)." | 2.75 | Effect of celecoxib combined with thoracic epidural analgesia on pain after thoracotomy. ( Deflandre, EP; Hubert, BM; Joris, JL; Ledoux, D; Libbrecht, D; Radermecker, M; Roediger, L; Senard, M, 2010) |
| "Celecoxib was well tolerated compared with placebo." | 2.73 | Analgesic efficacy of celecoxib in postoperative oral surgery pain: a single-dose, two-center, randomized, double-blind, active- and placebo-controlled study. ( Cheung, R; Kowalski, K; Krishnaswami, S, 2007) |
| "Patient satisfaction with their postoperative pain management was also higher in the Celecoxib group (94 +/- 8 vs 80 +/- 25, P<0." | 2.73 | Effect of short-term postoperative celecoxib administration on patient outcome after outpatient laparoscopic surgery. ( Eng, M; Nuangchamnong, N; Ogunnaike, B; Sacan, O; Tufanogullari, B; White, PF, 2007) |
| " The onset of analgesia (PID >or= 1) for all CS-706 doses occurred within 1 hour after dosing (P<0." | 2.73 | A randomized, double-blind, celecoxib- and placebo-controlled study of the effectiveness of CS-706 in acute postoperative dental pain. ( Bandy, DP; Daniels, SE; Desjardins, PJ; Lawson, JE; Link, AJ; Moberly, JB; Truitt, KE; Xu, J, 2007) |
| " Pain intensity was measured using the categorical scale and the primary efficacy variable was the summed pain intensity difference over 8 hours after dosing (SPID-8)." | 2.73 | Lumiracoxib 400 mg compared with celecoxib 400 mg and placebo for treating pain following dental surgery: a randomized, controlled trial. ( Davis, N; Fricke, J; Krammer, G; Yu, V, 2008) |
| "Celecoxib does not increase perioperative blood loss but reduces pain during the postoperative period after TKR." | 2.73 | Effects of celecoxib on blood loss, pain, and recovery of function after total knee replacement: a randomized placebo-controlled trial. ( Good, L; Lisander, B; Meunier, A, 2007) |
| "Postoperative pain was accessed during the first 8 hours and on the following 3 days using the visual analog scale (VAS), the 101-point numerical rate scale (NRS-101), and the four-point verbal rating scale (VRS-4)." | 2.72 | The use of celecoxib and dexamethasone for the prevention and control of postoperative pain after periodontal surgery. ( André dos Santos, F; Bianchi, A; Cavassim, R; Pilatti, GL; Tozetto, CW, 2006) |
| "Rofecoxib was also more effective than celecoxib in reducing pain and improving patient satisfaction after otolaryngologic surgery." | 2.71 | Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. ( Issioui, T; Klein, KW; Watcha, MF; White, PF, 2003) |
| "Celecoxib 400 mg was significantly more effective than 200 mg (and placebo) in reducing postoperative pain." | 2.71 | The efficacy of celecoxib premedication on postoperative pain and recovery times after ambulatory surgery: a dose-ranging study. ( Issioui, T; Klein, K; Recart, A; Shah, M; Stool, L; Watcha, MF; White, PF, 2003) |
| "Celecoxib has no effect on postoperative pain scores and PCA piritramide requirements." | 2.71 | Effect of celecoxib and dexamethasone on postoperative pain after lumbar disc surgery. ( Hussein, S; Karst, M; Kegel, T; Lüdemann, W; Lukas, A; Piepenbrock, S, 2003) |
| "One celecoxib-treated patient and 6 ketoprofen-treated patients ( P = 0." | 2.71 | Celecoxib and ketoprofen for pain management during tonsillectomy: a placebo-controlled clinical trial. ( Kokki, H; Linna, TJ; Nikanne, E; Salo, J, 2005) |
| " Timing of administration, inadequate dosing and possible altered pharmacokinetics in pregnancy may explain the lack of efficacy." | 2.71 | The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section. ( Irwin, MG; Lee, LH; Lim, J; Wong, CK, 2004) |
| "Ibuprofen liquigel is an encapsulated, solubilized potassium salt of ibuprofen that has a higher Cmax and shorter tmax than traditional ibuprofen solid-dosage formulations." | 2.70 | Efficacy and tolerability of nonprescription ibuprofen versus celecoxib for dental pain. ( Ashraf, E; Cooper, SA; Doyle, G; Jayawardena, S, 2002) |
| "5 hours) after dosing (P < or = 0." | 2.70 | Efficacy and tolerability of celecoxib versus hydrocodone/acetaminophen in the treatment of pain after ambulatory orthopedic surgery in adults. ( Brugger, A; Geis, GS; Gimbel, JS; Verburg, KM; Zhao, W, 2001) |
| "The morphine dose was significantly less in five of the six time intervals in the rofecoxib group compared with the celecoxib group." | 2.69 | Postoperative analgesic effects of celecoxib or rofecoxib after spinal fusion surgery. ( Connelly, NR; Reuben, SS, 2000) |
| " Celecoxib is administered at 200 mg or 400 mg dosage before the surgery." | 2.61 | The efficacy of celecoxib for pain management of arthroscopy: A meta-analysis of randomized controlled trials. ( Jiang, H; Li, P; Wan, R, 2019) |
| "Eleven studies (755 patients) assessed postoperative pain scores at 24 h and found a significant decrease with celecoxib use [mean difference (on a 0-10 pain scale) -1." | 2.53 | Preoperative celecoxib in noncardiac surgery: A systematic review and meta-analysis of randomised controlled trials. ( Choi, S; Clarke, H; Devereaux, PJ; Khan, JS; Margarido, C; McLellan, A, 2016) |
| "Celecoxib is a selective cyclo-oxygenase-2 (COX-2) inhibitor usually prescribed for the relief of chronic pain in osteoarthritis and rheumatoid arthritis." | 2.49 | Single dose oral celecoxib for acute postoperative pain in adults. ( Derry, S; Moore, RA, 2013) |
| "Celecoxib is a selective cyclo-oxygenase-2 (COX-2) inhibitor usually prescribed for the relief of chronic pain in osteoarthritis and rheumatoid arthritis." | 2.48 | Single dose oral celecoxib for acute postoperative pain in adults. ( Derry, S; Moore, RA, 2012) |
| "Celecoxib is a selective cyclo-oxygenase-2 (COX-2) inhibitor prescribed for the relief of chronic pain in osteoarthritis and rheumatoid arthritis." | 2.44 | Single dose oral celecoxib for acute postoperative pain in adults. ( Barden, J; Derry, S; McQuay, HJ; Moore, RA, 2008) |
| "Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor prescribed for the relief of chronic pain in osteoarthritis and rheumatoid arthritis." | 2.42 | Single dose oral celecoxib for postoperative pain. ( Barden, J; Edwards, JE; McQuay, HJ; Moore, RA, 2003) |
| "Postoperative pain is acute and, although it is preventable and/or treatable, it is often undertreated." | 2.42 | The burden of acute postoperative pain and the potential role of the COX-2-specific inhibitors. ( Laskin, B; Pashos, C; Peña, B; Stephens, J; Wong, J, 2003) |
| "Management of acute postoperative pain remains suboptimal; nearly 80 % of the patients report moderate to extreme pain following surgery." | 2.42 | [Cyclooxygenase-2 inhibitors in postoperative pain management]. ( Güneş, Y; Işik, G, 2004) |
| "· ERAS protocols improve postoperative pain control and lower postoperative opioid use." | 1.72 | Enhanced Recovery after Surgery Protocol to Improve Racial and Ethnic Disparities in Postcesarean Pain Management. ( Berghella, V; Cao, CD; Dayaratna, S; Felder, L; Konys, C; Mercier, R; Weerasooriya, N, 2022) |
| "Identical postoperative pain control including intravenous patient-controlled analgesia was applied for all patients." | 1.62 | Perioperative Outcomes of Patients Who Were Not Candidates for Additional Nonsteroidal Anti-inflammatory Drugs in a Multimodal Pain Control Regimen for Total Knee Arthroplasty. ( Chaibhuddanugul, N; Laoruengthana, A; Malisorn, S; Pongpirul, K; Rattanaprichavej, P; Tangsripong, P, 2021) |
| " Optimal standardized dosing and drug combination for preoperative multimodal analgesia remains to be elucidated." | 1.51 | Preoperative multimodal analgesia decreases 24-hour postoperative narcotic consumption in elective spinal fusion patients. ( Haffner, M; Hwang, J; Klineberg, E; Migdal, C; Nathe, R; Roberto, R; Saiz, AM, 2019) |
| "Treatment with celecoxib in the postoperative setting was associated with decreased mean use of opioids in oral (mean difference, 9." | 1.48 | Association of Celecoxib Use With Decreased Opioid Requirements After Head and Neck Cancer Surgery With Free Tissue Reconstruction. ( Buchmann, LO; Cannon, RB; Carpenter, PS; Hunt, JP; Kull, A; McCrary, H; Monroe, MM; Shepherd, HM; Torrecillas, V, 2018) |
| "To determine efficacy of postoperative pain control using nonopioid pain regimen vs traditional opioids for all aesthetic plastic surgery procedures." | 1.48 | Transition to Nonopioid Analgesia Does Not Impair Pain Control After Major Aesthetic Plastic Surgery. ( Lombana, NF; Moliver, CL; Nguyen, TC; Zavlin, D, 2018) |
| "Background Heterotopic ossification (HO) after joint surgery is always a disturbing problem for patients and surgeons." | 1.46 | The efficacy of a multimodal analgesia protocol in preventing heterotopic ossification after acetabular fractures surgery. ( Cheng, L; Long, HT; Sun, BH; Zhao, SS; Zhu, Y, 2017) |
| "This study was aimed to evaluate the efficacy of preemptive analgesia (PA) by using celecoxib combined with low-dose tramadol/acetaminophen (tramadol/APAP) in treating post-operative pain of patients undergoing unilateral total knee arthroplasty (TKA)." | 1.46 | Preemptive analgesia by using celecoxib combined with tramadol/APAP alleviates post-operative pain of patients undergoing total knee arthroplasty. ( Luo, J; Xu, Z; Zhang, H; Zhang, J; Zhou, A, 2017) |
| "Outcome measures were postsurgical pain at rest and during walking, consumption of opioids for pain rescue, knee swelling and knee range of motion, and complications." | 1.46 | Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty. ( Hansen, TB; Munk, S; Rytter, S; Stilling, M, 2017) |
| "Celecoxib is a selective COX-2 inhibitor and has a lower effect of platelet aggregation compared with conventional non-steroidal anti-inflammatory drugs (NSAIDs)." | 1.43 | A Comparison of Analgesic Effect between Loxoprofen and Celecoxib and the Frequency of the Hemorrhage Following Tonsillectomy. ( Ariki, M; Fukushima, N; Hirai, T; Miyahara, N; Yoshiga, A, 2016) |
| "To clarify the efficacy of postoperative pain management following laparoscopic gastrectomy (LG), we retrospectively compared pain assessments in patients who received fentanyl plus celecoxib with those who received epidural anesthesia." | 1.43 | A comparison between fentanyl plus celecoxib therapy and epidural anesthesia for postoperative pain management following laparoscopic gastrectomy. ( Homma, S; Kawamura, H; Shibasaki, S; Takahashi, M; Takahashi, N; Takahashi, S; Taketomi, A; Yosida, T, 2016) |
| "Celecoxib is not approved for the treatment of acute postoperative pain although a number of studies were carried out on the effectiveness and safety in patients undergoing surgery." | 1.40 | [Unexpected hemorrhage complications in association with celecoxib. Spontaneously reported case series after perioperative pain treatment in gynecological operations]. ( Arends, G; Augenstein, H; Brack, A; Brune, K; Gundert-Remy, U; Stammschulte, T, 2014) |
| "Gabapentin (Neurontin) is an agent commonly used to control neuropathic pain." | 1.35 | Combined preoperative use of celecoxib and gabapentin in the management of postoperative pain. ( Jackowe, DJ; Lee, M; Oyama, J; Parsa, AA; Parsa, FD; Sprouse-Blum, AS, 2009) |
| "Morphine consumption was significantly reduced in the interpleural group (p<0." | 1.35 | Interpleural analgesia in breast reconstruction. ( Caddy, CM; Colpaert, SD; Smith, PD, 2008) |
| "3." | 1.32 | Pharmacological characterisation of a rat model of incisional pain. ( Boulet, J; Gottshall, S; Harrison, J; Mark, L; Pearson, M; Walker, K; Whiteside, GT, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (1.56) | 18.2507 |
| 2000's | 58 (30.21) | 29.6817 |
| 2010's | 89 (46.35) | 24.3611 |
| 2020's | 42 (21.88) | 2.80 |
| Authors | Studies |
|---|---|
| Pu, C | 1 |
| Jiang, X | 1 |
| Sun, Y | 2 |
| Lin, H | 1 |
| Li, S | 1 |
| Yang, J | 2 |
| Wang, S | 1 |
| Liu, L | 1 |
| Shao, Y | 1 |
| Wang, J | 1 |
| Felder, L | 1 |
| Cao, CD | 1 |
| Konys, C | 1 |
| Weerasooriya, N | 1 |
| Mercier, R | 1 |
| Berghella, V | 1 |
| Dayaratna, S | 1 |
| Kardash, K | 2 |
| Harvey, E | 1 |
| Payne, S | 2 |
| Yang, SS | 1 |
| Giordano, T | 1 |
| Durkin, A | 1 |
| Simi, A | 1 |
| Shannon, M | 1 |
| Dailey, J | 1 |
| Facey, H | 1 |
| Ballester, L | 1 |
| Wetmore, RF | 1 |
| Germiller, JA | 1 |
| Guo, W | 1 |
| Liu, Y | 1 |
| Li, J | 2 |
| Passias, BJ | 1 |
| Johnson, DB | 1 |
| Schuette, HB | 1 |
| Secic, M | 1 |
| Heilbronner, B | 1 |
| Hyland, SJ | 1 |
| Sager, A | 1 |
| Viscusi, ER | 3 |
| de Leon-Casasola, O | 1 |
| Cebrecos, J | 2 |
| Jacobs, A | 1 |
| Morte, A | 2 |
| Ortiz, E | 2 |
| Sust, M | 3 |
| Vaqué, A | 3 |
| Gottlieb, I | 1 |
| Daniels, S | 4 |
| Gimbel, JS | 2 |
| Muse, D | 1 |
| Winkle, P | 1 |
| Kuss, ME | 1 |
| Videla, S | 2 |
| Gascón, N | 2 |
| Plata-Salamán, C | 3 |
| Lee, GC | 1 |
| Berkowitz, R | 1 |
| Hacker, S | 1 |
| Hu, J | 1 |
| Rechter, A | 1 |
| Jones, CA | 1 |
| Throckmorton, TW | 1 |
| Murphy, J | 1 |
| Eason, RR | 1 |
| Joyce, M | 1 |
| Bernholt, DL | 1 |
| Azar, FM | 1 |
| Brolin, TJ | 1 |
| Wang, Q | 2 |
| Zhang, W | 2 |
| Xiao, T | 1 |
| Wang, L | 2 |
| Ma, T | 2 |
| Kang, P | 2 |
| Langford, R | 1 |
| Fettiplace, J | 1 |
| Adeyemi, S | 1 |
| Raba, G | 1 |
| But-Husaim, L | 1 |
| Ni, JM | 1 |
| Zhu, X | 2 |
| Wang, P | 1 |
| Zhou, Y | 1 |
| Liu, X | 1 |
| Ding, C | 1 |
| Xiang, B | 1 |
| Yan, L | 1 |
| Qin, M | 1 |
| Ye, G | 1 |
| Xin, J | 1 |
| Li, M | 1 |
| Sui, X | 1 |
| Fu, Q | 1 |
| He, Z | 1 |
| Kukreja, P | 1 |
| Uppal, V | 1 |
| Kofskey, AM | 1 |
| Feinstein, J | 1 |
| Northern, T | 1 |
| Davis, C | 1 |
| Morgan, CJ | 1 |
| Kalagara, H | 1 |
| Degen, RM | 1 |
| Firth, A | 1 |
| Sehmbi, H | 1 |
| Martindale, A | 1 |
| Wanlin, S | 1 |
| Chen, C | 1 |
| Marsh, JD | 1 |
| Willits, K | 1 |
| Bryant, D | 1 |
| Zhang, K | 1 |
| Miao, X | 1 |
| Jiang, L | 1 |
| Cui, S | 1 |
| Liu, Z | 1 |
| Wang, Z | 1 |
| Li, Y | 4 |
| An, M | 1 |
| Ding, Y | 1 |
| Wang, C | 1 |
| Qiu, Y | 1 |
| Zhao, C | 1 |
| Boyev, A | 1 |
| Jain, AJ | 1 |
| Newhook, TE | 1 |
| Prakash, LR | 1 |
| Chiang, YJ | 1 |
| Bruno, ML | 1 |
| Arvide, EM | 1 |
| Dewhurst, WL | 1 |
| Kim, MP | 1 |
| Maxwell, JE | 1 |
| Ikoma, N | 1 |
| Snyder, RA | 1 |
| Lee, JE | 1 |
| Katz, MHG | 1 |
| Tzeng, CD | 1 |
| Ueda, K | 1 |
| Hayashi, M | 1 |
| Murakami, J | 1 |
| Tanaka, T | 1 |
| Utada, K | 1 |
| Hamano, K | 1 |
| Xie, L | 2 |
| Yang, RT | 1 |
| Lv, K | 1 |
| Zhou, HH | 1 |
| Li, Z | 1 |
| Wan, R | 1 |
| Li, P | 1 |
| Jiang, H | 1 |
| Evans, T | 1 |
| Nicholas, TA | 1 |
| Sutton, AV | 1 |
| Wysong, A | 1 |
| Zhuang, Q | 2 |
| Tao, L | 1 |
| Lin, J | 3 |
| Jin, J | 1 |
| Qian, W | 1 |
| Bian, Y | 2 |
| Dong, Y | 1 |
| Peng, H | 1 |
| Fan, Y | 1 |
| Wang, W | 2 |
| Feng, B | 2 |
| Gao, N | 1 |
| Sun, T | 3 |
| Zhang, M | 3 |
| Yan, S | 2 |
| Shen, B | 4 |
| Pei, F | 3 |
| Weng, X | 3 |
| Huynh, TQ | 1 |
| Patel, NR | 1 |
| Goldstein, ND | 1 |
| Makai, GE | 1 |
| Ramaseshan, AS | 1 |
| O'Sullivan, DM | 2 |
| Steinberg, AC | 2 |
| Tunitsky-Bitton, E | 1 |
| Xu, X | 2 |
| Liu, H | 1 |
| Hu, Y | 1 |
| Latif, D | 1 |
| Darweesh, FF | 1 |
| Osman, OM | 1 |
| Abdelhakim, AM | 1 |
| Nabil, H | 1 |
| Ashour, ASA | 1 |
| Mammoto, T | 2 |
| Fujie, K | 2 |
| Taguchi, N | 2 |
| Ma, E | 2 |
| Shimizu, T | 1 |
| Hashimoto, K | 2 |
| Burns, KA | 1 |
| Robbins, LM | 1 |
| LeMarr, AR | 1 |
| Childress, AL | 1 |
| Morton, DJ | 1 |
| Schroer, WC | 1 |
| Wilson, ML | 1 |
| Zangrilli, J | 1 |
| Gouda, N | 1 |
| Voskerijian, A | 1 |
| Wang, ML | 1 |
| Beredjiklian, PK | 1 |
| Rivlin, M | 1 |
| Saito, T | 1 |
| Iwamoto, S | 1 |
| Murotani, K | 1 |
| Hashimoto, A | 1 |
| Kurahashi, S | 1 |
| Fukami, Y | 1 |
| Komatsu, S | 1 |
| Kaneko, K | 1 |
| Mishima, H | 1 |
| Sano, T | 1 |
| Yu, Y | 1 |
| Gao, S | 1 |
| Yuen, VM | 1 |
| Choi, SW | 1 |
| Zhang, Y | 2 |
| He, B | 1 |
| Zhao, J | 1 |
| Ren, Q | 1 |
| Xu, S | 1 |
| Quan, Z | 1 |
| Ou, Y | 1 |
| Ma, L | 1 |
| Zhang, L | 1 |
| Wang, H | 1 |
| Jiang, C | 1 |
| Laoruengthana, A | 1 |
| Chaibhuddanugul, N | 1 |
| Rattanaprichavej, P | 1 |
| Malisorn, S | 1 |
| Tangsripong, P | 1 |
| Pongpirul, K | 1 |
| Liu, J | 2 |
| Di, J | 1 |
| Xing, E | 1 |
| Isiordia-Espinoza, MA | 1 |
| Franco-González, MA | 1 |
| Alonso-Castro, ÁJ | 1 |
| Franco-de la Torre, L | 1 |
| Singla, N | 1 |
| Bertoch, T | 1 |
| Shenoy, S | 1 |
| Munjal, S | 1 |
| Parsa, FD | 2 |
| Cheng, J | 1 |
| Stephan, B | 1 |
| Castel, N | 1 |
| Kim, L | 1 |
| Murariu, D | 1 |
| Parsa, AA | 3 |
| Eloy, JD | 1 |
| Anthony, C | 1 |
| Amin, S | 1 |
| Caparó, M | 1 |
| Reilly, MC | 1 |
| Shulman, S | 1 |
| Xu, Z | 1 |
| Zhang, H | 1 |
| Luo, J | 1 |
| Zhou, A | 1 |
| Zhang, J | 1 |
| Cheng, L | 1 |
| Long, HT | 1 |
| Sun, BH | 1 |
| Zhao, SS | 1 |
| Zhu, Y | 1 |
| Tang, J | 2 |
| Fan, J | 1 |
| Yao, Y | 1 |
| Cai, W | 1 |
| Yin, G | 1 |
| Zhou, W | 1 |
| Reagan, KML | 1 |
| Gannon, R | 1 |
| Zhou, F | 1 |
| Du, Y | 2 |
| Huang, W | 1 |
| Shan, J | 1 |
| Xu, G | 1 |
| White, PB | 1 |
| Ramkumar, PN | 1 |
| Meftah, M | 1 |
| Ghazi, N | 1 |
| Ranawat, AS | 1 |
| Ranawat, CS | 1 |
| Stepan, JG | 2 |
| London, DA | 2 |
| Osei, DA | 1 |
| Boyer, MI | 2 |
| Dardas, AZ | 2 |
| Calfee, RP | 2 |
| Tintara, H | 1 |
| Voradithi, P | 1 |
| Choobun, T | 1 |
| Wright, R | 1 |
| Wright, J | 1 |
| Perry, K | 1 |
| Wright, D | 1 |
| Nguyen, TC | 1 |
| Lombana, NF | 1 |
| Zavlin, D | 1 |
| Moliver, CL | 1 |
| Steurer, J | 1 |
| Carpenter, PS | 1 |
| Shepherd, HM | 1 |
| McCrary, H | 1 |
| Torrecillas, V | 1 |
| Kull, A | 1 |
| Hunt, JP | 1 |
| Monroe, MM | 1 |
| Buchmann, LO | 1 |
| Cannon, RB | 1 |
| Yang, T | 1 |
| Si, H | 1 |
| Wu, Y | 1 |
| Zeng, Y | 1 |
| López-Cedrún, J | 1 |
| Burgueño, M | 1 |
| Juárez, I | 1 |
| Aboul-Hosn, S | 1 |
| Martín-Granizo, R | 1 |
| Grau, J | 1 |
| Puche, M | 1 |
| Gil-Diez, JL | 1 |
| Hueto, JA | 1 |
| Monner, A | 1 |
| Castro Alves, LJ | 1 |
| Kendall, MC | 1 |
| Osei, D | 1 |
| Hirai, T | 1 |
| Fukushima, N | 1 |
| Miyahara, N | 1 |
| Yoshiga, A | 1 |
| Ariki, M | 1 |
| Pitchon, DN | 1 |
| Dayan, AC | 1 |
| Schwenk, ES | 1 |
| Baratta, JL | 1 |
| Ulm, MA | 1 |
| ElNaggar, AC | 1 |
| Tillmanns, TD | 1 |
| Xiao, X | 1 |
| Zhang, Q | 1 |
| Ouyang, Z | 1 |
| Guo, X | 1 |
| Horsley, RD | 1 |
| Vogels, ED | 1 |
| McField, DAP | 1 |
| Parker, DM | 1 |
| Medico, C | 1 |
| Dove, J | 1 |
| Fluck, M | 1 |
| Gabrielsen, JD | 1 |
| Gionfriddo, MR | 1 |
| Petrick, AT | 1 |
| Wang, F | 1 |
| Akinbade, AO | 2 |
| Ndukwe, KC | 2 |
| Owotade, FJ | 2 |
| Isola, G | 2 |
| Matarese, M | 1 |
| Ramaglia, L | 1 |
| Cicciù, M | 1 |
| Matarese, G | 2 |
| Gülses, A | 1 |
| Açil, Y | 1 |
| Wiltfang, J | 1 |
| Haffner, M | 1 |
| Saiz, AM | 1 |
| Nathe, R | 1 |
| Hwang, J | 1 |
| Migdal, C | 1 |
| Klineberg, E | 1 |
| Roberto, R | 1 |
| Gong, L | 1 |
| Dong, JY | 1 |
| Li, ZR | 1 |
| Mehta, A | 1 |
| Hsiao, W | 1 |
| King, P | 1 |
| Schlegel, PN | 1 |
| Sugai, DY | 1 |
| Deptula, PL | 1 |
| Don Parsa, F | 1 |
| Michelson, JD | 1 |
| Addante, RA | 1 |
| Charlson, MD | 1 |
| Garcia, RM | 1 |
| Cassinelli, EH | 1 |
| Messerschmitt, PJ | 1 |
| Furey, CG | 1 |
| Bohlman, HH | 1 |
| Mardani-Kivi, M | 1 |
| Karimi Mobarakeh, M | 1 |
| Haghighi, M | 1 |
| Naderi-Nabi, B | 1 |
| Sedighi-Nejad, A | 1 |
| Hashemi-Motlagh, K | 1 |
| Saheb-Ekhtiari, K | 1 |
| Derry, S | 3 |
| Moore, RA | 4 |
| Zhang, Z | 1 |
| Zhu, W | 1 |
| Zhu, L | 1 |
| Altman, R | 1 |
| Young, CL | 1 |
| Cillo, JE | 1 |
| Dattilo, DJ | 1 |
| Yamashita, Y | 1 |
| Sano, N | 1 |
| Shimohira, D | 1 |
| Danjo, A | 1 |
| Goto, M | 1 |
| Stammschulte, T | 1 |
| Brune, K | 1 |
| Brack, A | 1 |
| Augenstein, H | 1 |
| Arends, G | 1 |
| Gundert-Remy, U | 1 |
| Kazerooni, R | 2 |
| Tran, MH | 1 |
| Rytter, S | 1 |
| Stilling, M | 1 |
| Munk, S | 1 |
| Hansen, TB | 1 |
| Murto, K | 1 |
| Lamontagne, C | 1 |
| McFaul, C | 1 |
| MacCormick, J | 1 |
| Ramakko, KA | 1 |
| Aglipay, M | 1 |
| Rosen, D | 1 |
| Vaillancourt, R | 1 |
| Sekiguchi, H | 1 |
| Inoue, G | 1 |
| Nakazawa, T | 1 |
| Imura, T | 1 |
| Saito, W | 1 |
| Uchida, K | 1 |
| Miyagi, M | 1 |
| Takahira, N | 1 |
| Takaso, M | 1 |
| Yang, X | 1 |
| Peng, N | 1 |
| Li, N | 1 |
| Kim, SI | 1 |
| Ha, KY | 1 |
| Oh, IS | 1 |
| Jolly, C | 1 |
| Jathières, F | 1 |
| Keïta, H | 1 |
| Jaouen, E | 1 |
| Guyot, B | 1 |
| Torre, A | 1 |
| Gurunathan, U | 1 |
| Rapchuk, IL | 1 |
| King, G | 1 |
| Barnett, AG | 1 |
| Fraser, JF | 1 |
| Thomazeau, J | 1 |
| Rouquette, A | 1 |
| Martinez, V | 1 |
| Rabuel, C | 1 |
| Prince, N | 1 |
| Laplanche, JL | 1 |
| Nizard, R | 1 |
| Bergmann, JF | 1 |
| Perrot, S | 1 |
| Lloret-Linares, C | 1 |
| Clarke, H | 3 |
| Pagé, GM | 1 |
| McCartney, CJ | 1 |
| Huang, A | 1 |
| Stratford, P | 1 |
| Andrion, J | 1 |
| Kennedy, D | 1 |
| Awad, IT | 1 |
| Gollish, J | 1 |
| Kay, J | 2 |
| Katz, J | 2 |
| Shibasaki, S | 2 |
| Kawamura, H | 2 |
| Homma, S | 2 |
| Yosida, T | 1 |
| Takahashi, S | 1 |
| Takahashi, M | 1 |
| Takahashi, N | 2 |
| Taketomi, A | 2 |
| Morgan, B | 1 |
| Stanik-Hutt, J | 1 |
| Khan, JS | 1 |
| Margarido, C | 1 |
| Devereaux, PJ | 1 |
| McLellan, A | 1 |
| Choi, S | 1 |
| Mamizuka, N | 1 |
| Hirano, A | 1 |
| Yamazaki, M | 1 |
| Ueno, S | 1 |
| Aghadavoudi, O | 1 |
| Saryazdi, HH | 1 |
| Shafa, A | 1 |
| Ramezani, A | 1 |
| Onda, A | 1 |
| Ogoshi, A | 1 |
| Itoh, M | 1 |
| Nakagawa, T | 1 |
| Kimura, M | 1 |
| Yoshida, T | 1 |
| Shimokuni, T | 1 |
| Sakihama, H | 1 |
| Aoki, T | 1 |
| Ota, Y | 1 |
| Mori, Y | 1 |
| Otsuru, M | 1 |
| Ota, M | 1 |
| Kaneko, A | 2 |
| Van Daele, DJ | 1 |
| Bodeker, KL | 1 |
| Trask, DK | 1 |
| Jiang, J | 1 |
| Hokuto, D | 1 |
| Nomi, T | 1 |
| Kawaguchi, C | 1 |
| Yoshikawa, T | 1 |
| Yasuda, S | 1 |
| Obara, S | 1 |
| Yamato, I | 1 |
| Yamada, T | 1 |
| Kanehiro, H | 1 |
| Nakajima, Y | 1 |
| van Helmond, N | 1 |
| Steegers, MA | 1 |
| Filippini-de Moor, GP | 1 |
| Vissers, KC | 1 |
| Wilder-Smith, OH | 1 |
| Klapwijk, LC | 1 |
| Mathijssen, NM | 1 |
| Van Egmond, JC | 1 |
| Verbeek, BM | 1 |
| Vehmeijer, SB | 1 |
| Hiller, JG | 1 |
| Sampurno, S | 1 |
| Millen, R | 1 |
| Kuruvilla, N | 1 |
| Ho, KM | 1 |
| Ramsay, R | 1 |
| Riedel, B | 1 |
| Ng, TT | 1 |
| Diamantaras, D | 1 |
| Priestley, J | 1 |
| Redman, J | 1 |
| De Silva, N | 1 |
| Mahanta, V | 1 |
| Kahlenberg, CA | 1 |
| Patel, RM | 1 |
| Knesek, M | 1 |
| Tjong, VK | 1 |
| Sonn, K | 1 |
| Terry, MA | 1 |
| Dorr, LD | 1 |
| Raya, J | 1 |
| Long, WT | 1 |
| Boutary, M | 1 |
| Sirianni, LE | 1 |
| Huang, YM | 1 |
| Wang, CM | 1 |
| Wang, CT | 1 |
| Lin, WP | 1 |
| Horng, LC | 1 |
| Jiang, CC | 1 |
| Gärtner, R | 3 |
| Callesen, T | 3 |
| Kroman, N | 3 |
| Kehlet, H | 4 |
| Sprouse-Blum, AS | 1 |
| Jackowe, DJ | 1 |
| Lee, M | 1 |
| Oyama, J | 1 |
| Barden, J | 2 |
| McQuay, HJ | 2 |
| Rawal, N | 1 |
| Sami Mebazaa, M | 1 |
| Frikha, N | 1 |
| Ben Hammouda, N | 1 |
| Mestiri, T | 1 |
| Mestiri, H | 1 |
| Khalfallah, T | 1 |
| Ben Ammar, MS | 1 |
| Tang, X | 1 |
| Zhou, ZK | 1 |
| Kang, PD | 1 |
| Pei, FX | 1 |
| Wattchow, DA | 1 |
| De Fontgalland, D | 1 |
| Bampton, PA | 1 |
| Leach, PL | 1 |
| McLaughlin, K | 1 |
| Costa, M | 1 |
| Lu, X | 1 |
| Li, K | 1 |
| Post, ZD | 1 |
| Restrepo, C | 1 |
| Kahl, LK | 1 |
| van de Leur, T | 1 |
| Purtill, JJ | 1 |
| Hozack, WJ | 1 |
| Mitsakakis, N | 1 |
| Trabulsi, EJ | 1 |
| Patel, J | 1 |
| Gomella, LG | 1 |
| Lallas, CD | 1 |
| Senard, M | 1 |
| Deflandre, EP | 1 |
| Ledoux, D | 1 |
| Roediger, L | 1 |
| Hubert, BM | 1 |
| Radermecker, M | 1 |
| Libbrecht, D | 1 |
| Joris, JL | 1 |
| Ittichaikulthol, W | 1 |
| Prachanpanich, N | 1 |
| Kositchaiwat, C | 1 |
| Intapan, T | 1 |
| Boonriong, T | 1 |
| Tangtrakulwanich, B | 1 |
| Glabglay, P | 1 |
| Nimmaanrat, S | 1 |
| White, PF | 6 |
| Wender, RH | 1 |
| Zhao, M | 1 |
| Time, M | 1 |
| Zaentz, A | 1 |
| Yumul, R | 1 |
| Sloninsky, A | 1 |
| Naruse, R | 1 |
| Kariger, R | 1 |
| Webb, T | 1 |
| Fermelia, DE | 1 |
| Tsushima, GK | 1 |
| Chelly, JE | 1 |
| Ploskanych, T | 1 |
| Dai, F | 1 |
| Nelson, JB | 1 |
| Steffens, JP | 1 |
| Santos, FA | 1 |
| Pilatti, GL | 2 |
| Zhao, H | 2 |
| Wang, Y | 2 |
| Feng, Y | 2 |
| Yang, BX | 1 |
| Xing, ZM | 1 |
| Wang, M | 1 |
| Yu, LS | 1 |
| Andersen, LØ | 1 |
| Otte, KS | 1 |
| Husted, H | 1 |
| Gaarn-Larsen, L | 1 |
| Kristensen, B | 1 |
| Yang, B | 1 |
| Xing, Z | 1 |
| Saito, K | 1 |
| Machii, K | 1 |
| Ohta, H | 1 |
| Ohkura, M | 1 |
| Suzuki, M | 1 |
| Dalury, DF | 1 |
| Lieberman, JR | 1 |
| Macdonald, SJ | 1 |
| Bounthavong, M | 1 |
| Tran, JN | 1 |
| Boggie, DT | 1 |
| Meyer, RS | 1 |
| Al-Sukhun, J | 1 |
| Al-Sukhun, S | 1 |
| Penttilä, H | 1 |
| Ashammakhi, N | 1 |
| Al-Sukhun, R | 1 |
| Manvelian, G | 1 |
| Gibofsky, A | 1 |
| Kang, H | 1 |
| Ha, YC | 1 |
| Kim, JY | 1 |
| Woo, YC | 1 |
| Lee, JS | 1 |
| Jang, EC | 1 |
| Khan, AA | 1 |
| Brahim, JS | 1 |
| Rowan, JS | 1 |
| Dionne, RA | 1 |
| Doyle, G | 1 |
| Jayawardena, S | 1 |
| Ashraf, E | 1 |
| Cooper, SA | 1 |
| Rowbotham, DJ | 1 |
| Malmstrom, K | 2 |
| Fricke, JR | 1 |
| Kotey, P | 2 |
| Kress, B | 1 |
| Morrison, B | 1 |
| Watcha, MF | 3 |
| Issioui, T | 3 |
| Klein, KW | 2 |
| Recart, A | 1 |
| Klein, K | 1 |
| Stool, L | 1 |
| Shah, M | 1 |
| Karamanlioğlu, B | 1 |
| Arar, C | 1 |
| Alagöl, A | 1 |
| Colak, A | 1 |
| Gemlik, I | 1 |
| Süt, N | 1 |
| Edwards, JE | 1 |
| Karst, M | 1 |
| Kegel, T | 1 |
| Lukas, A | 1 |
| Lüdemann, W | 1 |
| Hussein, S | 1 |
| Piepenbrock, S | 1 |
| Stephens, J | 1 |
| Laskin, B | 1 |
| Pashos, C | 1 |
| Peña, B | 1 |
| Wong, J | 1 |
| Whiteside, GT | 1 |
| Harrison, J | 1 |
| Boulet, J | 1 |
| Mark, L | 1 |
| Pearson, M | 1 |
| Gottshall, S | 1 |
| Walker, K | 1 |
| Coulter, DM | 1 |
| Clark, DW | 1 |
| Savage, RL | 1 |
| Burian, M | 1 |
| Geisslinger, G | 1 |
| Rømsing, J | 1 |
| Møiniche, S | 1 |
| Tamosiūnas, R | 1 |
| Gudas, R | 1 |
| Karbonskiene, A | 1 |
| Marchertiene, I | 1 |
| Kellstein, D | 1 |
| Ott, D | 1 |
| Jayawardene, S | 1 |
| Fricke, J | 2 |
| Lee, LH | 1 |
| Irwin, MG | 1 |
| Lim, J | 1 |
| Wong, CK | 1 |
| Güneş, Y | 1 |
| Işik, G | 1 |
| Nikanne, E | 1 |
| Kokki, H | 1 |
| Salo, J | 1 |
| Linna, TJ | 1 |
| Muratani, T | 1 |
| Doi, Y | 1 |
| Nishimura, W | 1 |
| Nishizawa, M | 1 |
| Minami, T | 1 |
| Ito, S | 1 |
| Reuben, SS | 6 |
| Ablett, D | 1 |
| Kaye, R | 1 |
| Alanoglu, Z | 1 |
| Ateş, Y | 1 |
| Orbey, BC | 1 |
| Türkçapar, AG | 1 |
| Meechan, J | 1 |
| Chamouard, P | 1 |
| Walter, P | 1 |
| Baumann, R | 1 |
| Poupon, R | 1 |
| Iohom, G | 1 |
| Abdalla, H | 1 |
| O'Brien, J | 1 |
| Szarvas, S | 1 |
| Larney, V | 1 |
| Buckley, E | 1 |
| Butler, M | 1 |
| Shorten, GD | 1 |
| Buvanendran, A | 1 |
| Kroin, JS | 1 |
| Raghunathan, K | 1 |
| André dos Santos, F | 1 |
| Bianchi, A | 1 |
| Cavassim, R | 1 |
| Tozetto, CW | 1 |
| Gajraj, NM | 1 |
| Sacan, O | 2 |
| Tufanogullari, B | 1 |
| Eng, M | 1 |
| Nuangchamnong, N | 1 |
| Ogunnaike, B | 1 |
| Moberly, JB | 1 |
| Xu, J | 1 |
| Desjardins, PJ | 2 |
| Daniels, SE | 1 |
| Bandy, DP | 1 |
| Lawson, JE | 1 |
| Link, AJ | 1 |
| Truitt, KE | 1 |
| Ekman, EF | 1 |
| Charron, D | 1 |
| Hickey, D | 1 |
| Tessler, MJ | 1 |
| Zukor, D | 1 |
| Velly, AM | 1 |
| Davis, N | 1 |
| Yu, V | 1 |
| Krammer, G | 1 |
| Meunier, A | 1 |
| Lisander, B | 1 |
| Good, L | 1 |
| Cheung, R | 1 |
| Krishnaswami, S | 1 |
| Kowalski, K | 1 |
| Colpaert, SD | 1 |
| Smith, PD | 1 |
| Caddy, CM | 1 |
| Coleman, J | 1 |
| Rohrich, RJ | 1 |
| Kenkel, JM | 1 |
| Ma, K | 1 |
| Zhou, QH | 1 |
| Chen, J | 1 |
| Du, DP | 1 |
| Ji, Y | 1 |
| Jiang, W | 1 |
| Fong, WP | 1 |
| Yang, LC | 1 |
| Wu, JI | 1 |
| Chen, HS | 1 |
| Tan, PH | 1 |
| Lefkowith, JB | 1 |
| Seidenberg, BC | 1 |
| Jeske, AH | 1 |
| Weisberg, NK | 1 |
| Becker, D | 1 |
| Connelly, NR | 1 |
| Brugger, A | 1 |
| Zhao, W | 1 |
| Verburg, KM | 1 |
| Geis, GS | 1 |
| Burgess, FW | 1 |
| Browning, RA | 1 |
| Coloma, M | 1 |
| Skrivanek, GD | 1 |
| Jones, SB | 1 |
| Thornton, KC | 1 |
| Marple, BF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Celecoxib for Pain Management After Tonsillectomy[NCT02934191] | Phase 2 | 172 participants (Actual) | Interventional | 2016-06-30 | Completed | ||
| A Randomized, Double-Blind, Multicenter, Placebo- and Active Comparator-Controlled Study to Evaluate Efficacy and Safety of MR308 in the Treatment of Acute Pain After Abdominal Hysterectomy Surgery Under General Anaesthesia (STARDOM2).[NCT03062644] | Phase 3 | 1,138 participants (Actual) | Interventional | 2017-04-05 | Completed | ||
| Pericapsular Nerve Group (PENG) Block and Lateral Femoral Cutaneous Nerve (LFCN) Block Versus Fascia Iliaca (FIC) Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis[NCT05916209] | 60 participants (Actual) | Observational | 2023-02-01 | Completed | |||
| Randomized Trial of Bupivacaine as Adjuvant for Post-operative Pain in Mohs Micrographic Surgery[NCT04362566] | Phase 4 | 174 participants (Actual) | Interventional | 2020-07-30 | Completed | ||
| A Study to Evaluate Efficacy and Safety of Postoperative Intravenous Parecoxib Sodium Followed by Oral Celecoxib Post Total Knee Arthroplasty in Osteoarthritis Patients[NCT02198924] | Phase 4 | 246 participants (Actual) | Interventional | 2014-12-31 | Completed | ||
| A Double-Blind Randomized Placebo-Controlled Clinical Trial of Preoperative Gabapentin Prior to Vaginal Apical Suspension Prolapse Procedures[NCT05658887] | Phase 4 | 110 participants (Anticipated) | Interventional | 2023-01-01 | Enrolling by invitation | ||
| Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management[NCT02703259] | Phase 4 | 137 participants (Actual) | Interventional | 2016-06-30 | Completed | ||
| Association Between Melatonin Use and Improved Sleep Quality After Total Knee Arthroplasty: A Randomized Control Trial[NCT05332717] | 176 participants (Actual) | Interventional | 2022-01-10 | Completed | |||
| A Randomized, Double-Blind, Placebo-Controlled, Efficacy, Tolerability, Safety and Pharmacokinetic Study of Single Doses of DFN-15 in Post-Surgical Dental Pain[NCT03554772] | Phase 2 | 120 participants (Actual) | Interventional | 2018-06-19 | Completed | ||
| Efficiency of Opioid-free Anesthesia (OFA) in Maxillofacial Surgery[NCT05031676] | 66 participants (Actual) | Interventional | 2019-02-15 | Completed | |||
| The Effect of Gabapentin on Postoperative Pain: a Randomized, Double Blind, Placebo Controlled Trial[NCT01546857] | Phase 4 | 34 participants (Actual) | Interventional | 2012-03-31 | Terminated (stopped due to No longer able to recruit subjects due to unavailability of orthopedic surgeon.) | ||
| Comparison Between USG-Guided Infiltration Popliteal Artery Capsule Knee Block Versus Adductor Canal Block Application as Postoperative Analgesia in Total Knee Prosthesis Under General Anesthesia: Randomized Clinical Trial[NCT05956275] | Phase 4 | 20 participants (Actual) | Interventional | 2020-12-08 | Completed | ||
| The Effect of a Non-Opioid Multimodal Pain (NOMO) Protocol in Decreasing Narcotic Use After Urogynecologic Surgery[NCT05386069] | Phase 3 | 11 participants (Actual) | Interventional | 2019-11-15 | Completed | ||
| Nurses' Knowledge and Attitudes Towards Opioids in Pain Management in North Cyprus[NCT04252443] | 127 participants (Actual) | Interventional | 2018-06-01 | Completed | |||
| Impact of Counseling and Education on Opioid Consumption After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial[NCT04885231] | 80 participants (Anticipated) | Interventional | 2021-05-12 | Active, not recruiting | |||
| Opiate Free Multimodal Pain Pathway in Elective Foot and Ankle Surgery: A Prospective Study[NCT04771741] | 72 participants (Actual) | Observational | 2020-12-01 | Completed | |||
| The Effectiveness of IV/PO Acetaminophen in the Perioperative Period in Reducing Opiate Use After Lumbar Spine Fusion: a Prospective, Randomized Controlled Trial[NCT03104816] | Phase 4 | 28 participants (Actual) | Interventional | 2016-10-31 | Terminated (stopped due to Could not get an approval from Department Reviewer for the study continuation.) | ||
| Erector Spinae Plane Block in Patients Undergoing Minimally Invasive Lumbar Spine Surgery: A Randomized Controlled Trial[NCT05856539] | 48 participants (Anticipated) | Interventional | 2023-05-15 | Recruiting | |||
| Is There Any Analgesic Benefit From Preoperative vs. Postoperative Etoricoxib Administration in Total Knee Arthroplasty?[NCT02534610] | 165 participants (Actual) | Interventional | 2014-01-31 | Completed | |||
| Opioid-Free Shoulder Arthroplasty[NCT03540030] | Phase 4 | 86 participants (Actual) | Interventional | 2016-09-30 | Completed | ||
| The Effect of Preoperative Steroids Injection on Pain and Oedema After Total Knee Arthroplasty . A Double -Blinded Randomized Controlled Study.[NCT04084912] | Phase 3 | 86 participants (Anticipated) | Interventional | 2020-01-01 | Not yet recruiting | ||
| Efficacy of Steroids on Functional Outcomes After Musculoskeletal Injuries of the Hand[NCT05003596] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
| Celecoxib for Pediatric Adenotonsillectomy: A Randomized Controlled Double Blinded Study[NCT00849966] | Phase 2 | 282 participants (Actual) | Interventional | 2009-08-31 | Completed | ||
| Tumor Hospital of Guangxi Medical University, China[NCT02569905] | Phase 4 | 166 participants (Actual) | Interventional | 2014-04-30 | Completed | ||
| The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis[NCT04033562] | Phase 4 | 2 participants (Actual) | Interventional | 2020-01-15 | Terminated (stopped due to limited enrollment and unable to enroll subjects to reach statistical significance) | ||
| Efficacy of a Single-shot Wound Infiltration With Bupivacaine/Adrenalin During Cesarean Section in Reducing Postoperative Pain. A Randomized Prospective Controlled Trial[NCT03395912] | 288 participants (Actual) | Interventional | 2018-01-25 | Completed | |||
| Ambulatory Gynecologic Surgery: Finding the Optimal Postoperative Opioid Prescription[NCT03588910] | Phase 2 | 120 participants (Actual) | Interventional | 2018-08-08 | Completed | ||
| Perioperative Use of Celecoxib to Improve Pain Control in Patients Undergoing Tonsillectomy: a Randomized, Double Blind, Placebo-controlled Trial[NCT00583453] | Phase 2 | 18 participants (Actual) | Interventional | 2007-10-31 | Completed | ||
| Effect of a Multimodal Pain Regimen on Pain Control, Patient Satisfaction and Narcotic Use in Orthopaedic Trauma Patients[NCT02160301] | Phase 4 | 0 participants (Actual) | Interventional | 2017-11-30 | Withdrawn (stopped due to Insufficient infrastructure/funding for enrollment) | ||
| Perioperative Pain Control With Celecoxib (Celebrex) in Total Knee Arthroplasty[NCT00598234] | Phase 4 | 120 participants (Anticipated) | Interventional | 2006-09-30 | Completed | ||
| Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543] | 90 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| Combined General Anesthesia Plus Paravertebral Block Versus General Anesthesia Plus Opioid Analgesia for Breast Cancer Surgery: A Prospective Randomized Trial[NCT01904266] | 60 participants (Actual) | Interventional | 2013-05-31 | Completed | |||
| Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study[NCT04875559] | 236 participants (Actual) | Observational [Patient Registry] | 2021-04-19 | Completed | |||
| Comparing Etoricoxib and Celecoxib for Preemptive Analgesia for Acute Postoperative Pain in Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial[NCT01017380] | Phase 3 | 30 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| Psychosocial and Psychophysical Factors Influencing the Effect of Preemptive Systemic Analgesia in Combination With Regional Anesthesia on Postoperative Pain Following Upper Limb Surgery[NCT05248152] | 90 participants (Anticipated) | Interventional | 2022-01-13 | Recruiting | |||
| Post-operative Analgesia in Elective, Soft-tissue Hand Surgery: A Randomized, Double Blind Comparison of Acetaminophen/Ibuprofen Versus Acetaminophen/Hydrocodone[NCT02029235] | Phase 4 | 72 participants (Actual) | Interventional | 2015-02-10 | Terminated (stopped due to Early termination due to slower than anticipated recruitment.) | ||
| Effect of Celecoxib on Postoperative Narcotic Use and Disease Severity in Patients With Aspirin-exacerbated Respiratory Disease and Chronic Rhinosinusitis: a Randomised Controlled Trial[NCT04147013] | Phase 4 | 44 participants (Anticipated) | Interventional | 2020-02-18 | Recruiting | ||
| A Randomized, Double-Blind, Multicenter, Comparative Study To Evaluate Efficacy And Safety Of An Additional Dose Of Celecoxib (YM177) In The Treatment Of Acute Pain After Oral Surgery Lateral Mandibular Impacted Third Molar Tooth Extraction[NCT01062113] | Phase 2 | 255 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures: A Randomized Controlled Trial[NCT02793947] | Phase 4 | 102 participants (Actual) | Interventional | 2015-05-31 | Completed | ||
| Analgesic Efficacy of Adductor Canal Block (ACB) Before and After Primary Total Knee Arthroplasty (TKA): A Prospective Randomized Trial to Compare Postoperative Clinical Outcomes[NCT02908711] | Phase 4 | 50 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder[NCT02588027] | 100 participants (Anticipated) | Interventional | 2015-10-31 | Active, not recruiting | |||
| Analgesic Efficacy of Quadaratus Lumborum Block (QLB) for Laparoscopic Colectomy Surgery: A Prospective Observational Case Control Trial to Evaluate Clinical Outcomes[NCT03017638] | 14 participants (Actual) | Observational | 2017-02-27 | Completed | |||
| Lumbar Erector Spinae Plane Block: Cadaveric Study[NCT04166188] | 7 participants (Actual) | Interventional | 2019-06-01 | Completed | |||
| The Effect of Perioperative Systemic Lidocaine on Quality of Recovery After Cesarean Delivery[NCT02257346] | 0 participants (Actual) | Interventional | 2014-11-01 | Withdrawn (stopped due to PI terminated study with no subjects enrolled.) | |||
| The Effect of Perioperative Systemic Lidocaine on Quality of Recovery After Outpatient Gynecologic Laparoscopy[NCT01250002] | 70 participants (Actual) | Interventional | 2010-11-30 | Completed | |||
| Erector Spinae Plane Block (ESPB): A New Technique for Perioperative Pain Control in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.[NCT03691935] | Phase 4 | 40 participants (Anticipated) | Interventional | 2018-09-28 | Enrolling by invitation | ||
| Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy for Herniated Lumbar Discs Is There a Role? - A Randomized Control Trial[NCT04182997] | Phase 4 | 200 participants (Anticipated) | Interventional | 2019-11-21 | Recruiting | ||
| Parecoxib as an Adjuvant to Scalp Nerve Blocks for Relief of Post-craniotomy Pain[NCT04034836] | Phase 4 | 132 participants (Anticipated) | Interventional | 2019-10-12 | Recruiting | ||
| Effect of Toradol on Post-operative Foot and Ankle Healing[NCT03727048] | Phase 4 | 128 participants (Actual) | Interventional | 2016-08-31 | Completed | ||
| Propofol Sedation During Endoscopic Retrograde Cholangiopancreatography: A Comparison Between Conventional Versus Bispectral Index Guided Approach and Effect of Diclofenac Sodium Along With Topical Pharyngeal Anaesthesia[NCT04860167] | 90 participants (Actual) | Interventional | 2018-09-10 | Completed | |||
| A Randomized, Double-blind, Double-dummy, Parallel Group, Single-center Study Evaluating the Analgesic Effect of Single Doses of Lumiracoxib 400 mg, Celecoxib 400 mg and Placebo in the Treatment of Post-dental Surgery Pain[NCT00348491] | Phase 4 | 364 participants | Interventional | 2006-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The total amount of rescue pain medication consumed in the 2-week postop period will be compared between the two treatment groups. (NCT02934191)
Timeframe: 2 weeks post-operative
| Intervention | mg/kg (Mean) |
|---|---|
| Acetaminophen/Oxycodone + Celecoxib | 1.03 |
| Acetaminophen/Oxycodone + Placebo | 1.40 |
The number of days on narcotic pain medication following surgery will be compared between the two treatment groups (NCT02934191)
Timeframe: 2 weeks post-operative
| Intervention | Days (Mean) |
|---|---|
| Acetaminophen/Oxycodone + Celecoxib | 5.00 |
| Acetaminophen/Oxycodone + Placebo | 5.75 |
Assessment of the amount of narcotic use postoperatively at 2 weeks. will use opioid equivalence table to convert all narcotic use to oxycodone equivalents (NCT02703259)
Timeframe: 2 weeks
| Intervention | morphine milligram equivalents (Mean) |
|---|---|
| Gabapentin | 167.2 |
| Control | 187.3 |
Assessment of the amount of narcotic use postoperatively at 24 hours. will use opioid equivalence table to convert all narcotic use to oxycodone equivalents (NCT02703259)
Timeframe: 24 hours
| Intervention | morphine milligram equivalents (Mean) |
|---|---|
| Gabapentin | 158.8 |
| Control | 175.0 |
"Assessment of the subject pain score postoperatively at 2 weeks. will use a numeric analog scale from 0-10.~The pain scale ranging from 0-10 with 0 representing No Pain and 10 representing the Worst Pain Possible" (NCT02703259)
Timeframe: 2 weeks
| Intervention | score on a scale (Mean) |
|---|---|
| Gabapentin | 1.3 |
| Control | 1.4 |
Pain score assesses patient subjective pain via patient reported numeric analogue scale, range 0-10 with 0 being no pain and 10 being severe pain. (NCT02703259)
Timeframe: 24 hours
| Intervention | score on a scale (Mean) |
|---|---|
| Gabapentin | 3.4 |
| Control | 3.4 |
Will assess for known symptoms of gabapentin postoperatively at 2 weeks. We will survey subjects regarding their experience of the following symptoms: dizziness/drowsiness, fatigue, loss of balance, blurry vision, tremulousness, swelling, nausea, vomiting, diarrhea, and allergic reaction (NCT02703259)
Timeframe: 2 weeks
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Dizziness | Blurred vision | Somnolence | Difficulty walking | Tremulousness | Nausea | Vomiting | |
| Control | 8 | 3 | 21 | 5 | 2 | 7 | 1 |
| Gabapentin | 12 | 4 | 18 | 5 | 4 | 12 | 0 |
Will assess for known symptoms of gabapentin postoperatively at 24 hours. We will survey subjects regarding their experience of the following symptoms: dizziness/drowsiness, fatigue, loss of balance, blurry vision, tremulousness, swelling, nausea, vomiting, diarrhea, and allergic reaction (NCT02703259)
Timeframe: 24 hours
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Dizziness | Blurred Vision | Somnolence | Difficulty walking | Tremulousness | Nausea | Vomiting | |
| Control | 8 | 4 | 23 | 11 | 6 | 25 | 15 |
| Gabapentin | 17 | 7 | 20 | 13 | 11 | 24 | 9 |
"The primary endpoint is the Summed Pain Intensity Difference over the first 6 hours (SPID6) after dosing compared between DFN-15 and placebo. Pain intensity (P) will be measured at timepoints of 15, 30, and 45 minutes and 1, 1.5, 2, 3, 4, 5 and 6, hours after baseline ,using 11-point Pain Intensity Numerical Rating Scale (NPRS). Zero (0) equals no pain and Ten (10) equals worst pain imaginable.~SPID6 is created by summing the time weighted pain intensity differences (PID) scores using the area under the PID curve methodology. All SPID calculations will be performed using the standard trapezoidal rule SPIDx =∑_(i=0)^x▒((〖PID〗_i+〖PID〗_(i+1))/2) * (T_(i+1)- T_i ) Where: PID_i = P_i - PBL (Pain score at time i and Pain score at Baseline), and (T_i+1 - T_i) is the Time difference in minutes between time i and time i+1.~Therefore, SPID6 values may theoretically range between a maximum score of 0 ( no improvement) and a minimum score of -3525 (best improvement)" (NCT03554772)
Timeframe: 6 hours post dose
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | -420.2 |
| DFN-15 (Celecoxib Oral Solution) 62.5 mg | -1101.0 |
| DFN-15 (Celecoxib Oral Solution) 125 mg | -1771.7 |
| DFN-15 (Celecoxib Oral Solution) 250 mg | -1463.5 |
Patient Controlled Analgesia use over 48 hours reported in Morphine equivalent dosage. (NCT01546857)
Timeframe: 48 hours post operatively
| Intervention | mg (Mean) |
|---|---|
| Placebo | 11.88 |
| Gabapentin | 11.02 |
Severity of pain measure on a scale from zero to ten. Zero no pain to ten severe pain. (NCT01546857)
Timeframe: 48 hours post operatively
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | 5.15 |
| Gabapentin | 4.38 |
A questionnaire was administered asking participants about the quality of their sleep on the night of surgery asked on postoperative day 1, and on the first postoperative night ( POD 2) . Scored on a scale of zero to 3. Zero meaning poor postoperative sleep and 3 indicating better postoperative sleep. (NCT01546857)
Timeframe: Night of surgery (POD 1) and Postoperative Day 2.(POD 2)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| POD 1 | POD 2 | |
| Gabapentin | 1.235 | 0.647 |
| Placebo | 1.333 | 1 |
Determine the impact of administering a supplemental non-opioid analgesic drug such as IV/oral acetaminophen on total opioid dose administered over the perioperative period. (NCT03104816)
Timeframe: Within 24 hours after surgery
| Intervention | mg (Mean) | |
|---|---|---|
| PACU dose | Ward dose | |
| Acetaminophen IV Soln 10 MG/ML (A) | 1.2 | 9.8 |
| Hydromorphone (Control Arm) (C) | 1.7 | 13 |
| PO Acetaminophen (B) | 1.3 | 10.4 |
American Shoulder and Elbow Surgeons (ASES) Shoulder Score for pain and function. Range 0-100. Low score = worse shoulder condition. Function, disability, and pain subscores (all ranges 0-50), and are summed for total ASES score. (NCT03540030)
Timeframe: 2 Weeks
| Intervention | units on a scale (Median) |
|---|---|
| Observational | 54.3 |
| Non-Opioid Intervention | 54.2 |
Morphine milli-equivalents In-hospital post-operative. Continuous scale of MME, no defined better/worse. Measured as number and dose of medications taken. For example, if the patient received an opioid, the drug and dose was recorded and converted to MME. A time frame of when to assess opioid use in-hospital post-operative was not used but was a continuous monitor for rescue opioid from in-hospital post-operative through discharge. (NCT03540030)
Timeframe: In-hospital Stay
| Intervention | Morphine milli-equivalents (Median) |
|---|---|
| Observational | 45.0 |
| Non-Opioid Intervention | 19.0 |
Pain at patient discharge or 24-hours, whichever comes first - measured on a 0 (no pain) -10 (worst possible pain) numeric rating scale (NRS). A score of 0(no pain) is preferable to 10(worst possible pain) (NCT03540030)
Timeframe: 24 hours
| Intervention | score on a scale (Median) |
|---|---|
| Observational | 3.0 |
| Non-Opioid Intervention | 2.0 |
Simple Shoulder Test (SST) activity score. Range 0-12. 0 = worse activity score. (NCT03540030)
Timeframe: 2 Months
| Intervention | score on a scale (Median) |
|---|---|
| Observational | 6 |
| Non-Opioid Intervention | 6 |
Simple Shoulder Test (SST) activity score. Range 0-12. 0 = worse activity score. (NCT03540030)
Timeframe: 2 Weeks
| Intervention | score on a scale (Median) |
|---|---|
| Observational | 2.0 |
| Non-Opioid Intervention | 2.0 |
post-operative pain: measured on a 0 (no pain) -10 (worst) numeric rating scale (NRS) at 6hrs, 12hrs, 2 weeks, and 2 months. A score of 0(no pain) is preferable to 10(worst possible pain) (NCT03540030)
Timeframe: 6hrs, 12hrs, 2weeks, 2 months
| Intervention | score on a scale (Median) | |||
|---|---|---|---|---|
| 6 Hrs | 12 hrs | 2 weeks | 2 months | |
| Non-Opioid Intervention | 0.0 | 0 | 0.82 | 0 |
| Observational | 2 | 4 | 1.3 | 0.7 |
rate of constipation (NCT03540030)
Timeframe: 2 Months
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 4 | 27 | 4 |
| Observational | 7 | 21 | 2 |
rate of constipation (NCT03540030)
Timeframe: 2 Weeks
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 13 | 22 | 0 |
| Observational | 19 | 9 | 2 |
rate of falls (NCT03540030)
Timeframe: 2 Months
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 4 | 27 | 4 |
| Observational | 4 | 24 | 2 |
rate of falls (NCT03540030)
Timeframe: 2 Weeks
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 5 | 30 | 0 |
| Observational | 1 | 27 | 2 |
rate of nausea (NCT03540030)
Timeframe: 2 Months
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 1 | 30 | 0 |
| Observational | 0 | 28 | 2 |
rate of nausea (NCT03540030)
Timeframe: 2 Weeks
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 1 | 34 | 0 |
| Observational | 5 | 23 | 2 |
Satisfaction with overall pain using Numeric Pain Rating (NRS) scale. yes, no. No being better than yes. (NCT03540030)
Timeframe: 2 Months
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 29 | 2 | 4 |
| Observational | 23 | 5 | 2 |
Satisfaction with overall pain using Numeric Pain Rating (NRS) scale. yes, no. No being better than yes. (NCT03540030)
Timeframe: 2 Weeks
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 34 | 1 | 0 |
| Observational | 27 | 1 | 2 |
quality of life using VR-12 subscores. Physical Health (PCS) subscore and Mental Health (MCS) subscore, not summed. Range reported in weighted units. Physical Health subscore: 1 point increase in PCS is associated with 6% lower total health care expenditures, 5% lower pharmacy expenditures, 9% lower rate of hospital inpatient visits, 4% lower rate of medical provider visits, 5% lower rate of hospital outpatient visits. Mental Health sub score a 1 point increase in MCS is associated with 7% lower total health care expenditures, 4% lower pharmacy expenditures, 15% lower rate of hospital inpatient visits, and 4% lower rate of medical provider visits. Both PCS/MCS are score 0-100 with 100 indicating the highest level of health. (NCT03540030)
Timeframe: 2 Months
| Intervention | score on a scale (Median) | |
|---|---|---|
| PCS | MCS | |
| Non-Opioid Intervention | 40.3 | 60.8 |
| Observational | 38.4 | 58.7 |
quality of life using VR-12 subscores. Physical Health (PCS) subscore and Mental Health (MCS) subscore, not summed. Range reported in weighted units. Physical Health subscore: 1 point increase in PCS is associated with 6% lower total health care expenditures, 5% lower pharmacy expenditures, 9% lower rate of hospital inpatient visits, 4% lower rate of medical provider visits, 5% lower rate of hospital outpatient visits. Mental Health sub score a 1 point increase in MCS is associated with 7% lower total health care expenditures, 4% lower pharmacy expenditures, 15% lower rate of hospital inpatient visits, and 4% lower rate of medical provider visits. Both PCS/MCS are score 0-100 with 100 indicating the highest level of health. (NCT03540030)
Timeframe: 2 Weeks
| Intervention | score on a scale (Median) | |
|---|---|---|
| PCS | MCS | |
| Non-Opioid Intervention | 35.0 | 59.1 |
| Observational | 36.7 | 56.3 |
By chart review, unscheduled interactions with the healthcare system related to pain will be counted.These will include phone calls related to pain, unscheduled visits to the office or emergency department (NCT03588910)
Timeframe: 1 week post operative
| Intervention | Unscheduled patient contacts (Number) |
|---|---|
| Number of Oxycodone Tablets Typically Prescribed | 1 |
| Half the Number of Oxycodone Tablets Typically Prescribed | 4 |
During the survey phone call on day 7, participants will be asked to report the total number of oxycodone tablets used since the surgery. (NCT03588910)
Timeframe: 7 days post-operative
| Intervention | Oxycodone Tablets (Median) |
|---|---|
| Number of Oxycodone Tablets Typically Prescribed | 2.5 |
| Half the Number of Oxycodone Tablets Typically Prescribed | 2.0 |
During the survey phone call on day 1, participants will be asked to report the total number of oxycodone tablets use since the surgery. (NCT03588910)
Timeframe: 24 hours post-operative
| Intervention | Oxycodone Tablets (Median) |
|---|---|
| Number of Oxycodone Tablets Typically Prescribed | 1.0 |
| Half the Number of Oxycodone Tablets Typically Prescribed | 1.0 |
Participants will be surveyed during the phone call survey to rate pain score on a scale from 0 (no pain), to 10 (severe pain) (NCT03588910)
Timeframe: 1 day post operative
| Intervention | Score on Numeric Pain Scale (Median) |
|---|---|
| Number of Oxycodone Tablets Typically Prescribed | 5.0 |
| Half the Number of Oxycodone Tablets Typically Prescribed | 5 |
Participants will be surveyed during the phone call survey to rate pain score on a scale from 0 (no pain), to 10 (severe pain) (NCT03588910)
Timeframe: 7 days post operative
| Intervention | Score on Numeric Pain Scale (Median) |
|---|---|
| Number of Oxycodone Tablets Typically Prescribed | 2.0 |
| Half the Number of Oxycodone Tablets Typically Prescribed | 1.3 |
The incidence of post-operative hemorrhage, defined as post-operative bleeding requiring medical intervention or hospitalization during the 10 day post-operative follow-up period. (NCT00583453)
Timeframe: From operative day through 10 days post-operative
| Intervention | Participants (Count of Participants) |
|---|---|
| Celecoxib 200 mg Tablets | 0 |
| Placebo With Same Dosing Schedule as the Active Comparator Arm | 0 |
Participant reported acetaminophen use and its equivalent. Medication use was collected from reported participant journals. (NCT00583453)
Timeframe: From operative day through 10 days post-operative
| Intervention | mg (Mean) | |||
|---|---|---|---|---|
| Day 1 | Average, days 2 to 4 | Average, days 5 to 7 | Average, days 8 to 10 | |
| Celecoxib as Experimerimental Intervention | 2074 | 2245 | 2028 | 1418 |
| Placebo Control, Active Comparator | 3006 | 2934 | 3610 | 2483 |
Activity level, reported by participant utilizing a 10-point ordinal scale (0 = no activity, 10 = return to normal activities). Activity level was measured was collected once daily. (NCT00583453)
Timeframe: From operative day through 10 days post-operative
| Intervention | Activity score (units on a scale) (Mean) | |||
|---|---|---|---|---|
| Day 1 | Average, days 2 to 4 | Average, days 5 to 7 | Average, days 8 to 10 | |
| Celecoxib as Experimerimental Intervention | 2.8 | 3.1 | 5.4 | 7.4 |
| Placebo Control, Active Comparator | 4.5 | 4.1 | 3.7 | 5.7 |
Pain score as reported by participant, measured on a 10 point scale, where 0 = none and 10 = unbearable, collected once daily. (NCT00583453)
Timeframe: day of procedure through post-operative day 10
| Intervention | pain score (units on a scale) (Mean) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Maximum pain, day 1 | maximum pain, averaged across days 2 to 4 | maximum pain, averaged across days 5 to 7 | maximum pain, averaged across days 8 to 10 | Average pain, day 1 | Average pain, averaged across days 2 to 4 | Average pain, averaged across days 5 to 7 | Average pain, averaged across days 8 to 10 | Pain with drinking, day 1 | Pain with drinking, averaged across days 2 to 4 | Pain with drinking, averaged across days 5 to 7 | Pain with drinking, averaged across days 8 to 10 | Activity, day 1 | |
| Celecoxib 200 mg Tablets | 5.0 | 5.1 | 4.4 | 3.6 | 6.1 | 6.2 | 6.1 | 4.9 | 5.7 | 5.4 | 4.9 | 3.9 | 2.8 |
| Placebo With Same Dosing Schedule as the Active Comparator Arm | 6.0 | 6.0 | 5.9 | 4.0 | 7.3 | 7.6 | 7.4 | 5.7 | 6.7 | 6.6 | 5.9 | 4.1 | 4.5 |
Participant reported mophine equivalent use (NCT00583453)
Timeframe: From operative day through 10 days post-operative
| Intervention | mg (Mean) | |||
|---|---|---|---|---|
| Day 1 | Average, days 2 to 4 | Average, days 5 to 7 | Average, days 8 to 10 | |
| Celecoxib as Experimerimental Intervention | 28.9 | 30.4 | 27.8 | 13.2 |
| Placebo Control, Active Comparator | 55.0 | 72.4 | 69.7 | 38.3 |
"Subjects asked to fill out a patient diary recording their pain intensity level (on 100mm Visual Analog Scale) prior to taking study medication every 4 hours.~The daily average pain intensity levels are reported as a score on a scale of 0-100, with higher score meaning worse outcome.~The daily average pain levels were assessed daily for 1 week post-operatively, then compared between the 2 groups using a two-group Student's t-test." (NCT02029235)
Timeframe: 1 week post-operatively
| Intervention | score on a scale (0-100, higher = worse) (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Daily average pain intensity level on PostOp Day 1 | Daily average pain intensity level on PostOp Day 2 | Daily average pain intensity level on PostOp Day 3 | Daily average pain intensity levelon PostOp Day 4 | Daily average pain intensity level on PostOp Day 5 | Daily average pain intensity level on PostOp Day 6 | Daily average pain intensity level on PostOp Day 7 | |
| Acetaminophen/Hydrocodone (AH) Group | 24.07 | 30.16 | 22.11 | 18.53 | 16.61 | 13.58 | 13.00 |
| Acetaminophen/Ibuprofen (AIBU) Group | 22.17 | 22.22 | 15.67 | 13.17 | 14.03 | 13.44 | 12.67 |
"Subjects asked to fill out a patient diary recording their pain relief (on a Likert scale) one hour after taking study medication every 4 hours.~Daily average pain relief scores are reported as a score on a scale of 0-3, with higher score meaning better outcome.~The daily average pain relief scores were assessed daily for 1 week post-operatively, then compared using generalized linear mixed-effects models" (NCT02029235)
Timeframe: 1 week postoperatively
| Intervention | score on a scale (0-3, higher = better) (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Daily average pain relief on PostOp Day 1 | Daily average pain relief on PostOp Day 2 | Daily average pain relief on PostOp Day 3 | Daily average pain relief on PostOp Day 4 | Daily average pain relief on PostOp Day 5 | Daily average pain relief on PostOp Day 6 | Daily average pain relief on PostOp Day 7 | |
| Acetaminophen/Hydrocodone (AH) Group | 1.53 | 1.76 | 2.33 | 2.46 | 2.54 | 2.84 | 2.88 |
| Acetaminophen/Ibuprofen (AIBU) Group | 1.84 | 2.27 | 2.63 | 2.91 | 2.88 | 2.87 | 2.96 |
The differences in PI were obtained by subtracting the PI at each time point from the Baseline PI score. (NCT01062113)
Timeframe: Pre-additional dose (baseline) and 2 hours post-additional dose
| Intervention | mm (Mean) |
|---|---|
| Additional Dose Celecoxib 200 mg | 33.4 |
| Additional Dose Placebo | 12.3 |
"Patient's impression was assessed by self-report and was entered in the patient diary, based on the following categories: Excellent, Good, Fair and Poor.~Efficacy rate was calculated from the following formula, The number of participants assessed as Excellent or Good over total participants multiplied by 100." (NCT01062113)
Timeframe: 2 hours post-additional dose
| Intervention | percentage of participants (Number) |
|---|---|
| Additional Dose Celecoxib 200 mg | 64.1 |
| Additional Dose Placebo | 25.9 |
The Pain intensity was recorded on the 100 mm VAS in the patient diary, where 0 mm=no pain, 100 mm=unbearable maximal pain. (NCT01062113)
Timeframe: 2 hours post-additional dose
| Intervention | mm (Mean) |
|---|---|
| Additional Dose Celecoxib 200 mg | 35.8 |
| Additional Dose Placebo | 51.9 |
"Pain intensity was entered in the patient diary on the following categories: No pain, Mild pain, Moderate pain and Severe pain." (NCT01062113)
Timeframe: 2 hours after additional dose
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| None | Mild | Moderate | Severe | |
| Additional Dose Celecoxib 200mg | 11 | 34 | 18 | 1 |
| Additional Dose Placebo | 3 | 24 | 28 | 3 |
Patients will be monitored every 15 minutes in the recovery room and every 4 hours for the first two post-operative days by nursing personnel for medication side effects related to ropivacaine toxicity including blurred vision, hearing problems, transient peripheral paralysis, dizziness, convulsion, uncontrolled muscle contraction, hypotension, bradycardia, and new onset arrhythmia. (NCT02793947)
Timeframe: 48 hours following surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Peri-incisional Injection | 0 |
| Control (no Injection) | 0 |
Parenteral and oral narcotic agents will be utilized by patients for post-operative pain control per the standard of care. No alterations in narcotic prescription behavior will be observed for this study. (NCT02793947)
Timeframe: Narcotic consumption will be recorded every 8 hours for the first two post-operative days.
| Intervention | mg of morphine (Mean) |
|---|---|
| Peri-incisional Injection | 5.0 |
| Control (no Injection) | 9.7 |
"Patients will describe their current level of comfort on a 10 point scale while at rest. Zero corresponds to no pain and ten corresponds to the most extreme possible pain. Visual analog scores will be collected by nursing staff who are blinded to the treatment allocation." (NCT02793947)
Timeframe: Pain assessment will be collected immediately prior to surgery (pre-op), immediately following surgery in the post-anesthesia care unit (PACU), and every 4 hours following surgery for the first two post-operative days (48 hours total; 4H-48H)
| Intervention | units on a scale (Median) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre-op | PACU | 4H | 8H | 12H | 16H | 20H | 24H | 28H | 32H | 36H | 40H | 44H | 48H | |
| Control (no Injection) | 5.0 | 3.2 | 5.0 | 5.0 | 5.0 | 4.0 | 4.0 | 4.0 | 3.5 | 5.0 | 4.0 | 3.5 | 4.0 | 3.0 |
| Peri-incisional Injection | 5.0 | 1.6 | 1.0 | 2.0 | 3.5 | 3.5 | 4.0 | 3.0 | 3.0 | 3.0 | 4.0 | 3.0 | 3.0 | 3.0 |
opioid consumption (morphine equivalents)post operatively (NCT01250002)
Timeframe: 24 hours
| Intervention | mg (Median) |
|---|---|
| Group A (Study Group) Lidocaine | 20 |
| Placebo | 30 |
Quality of recovery 40 score on the day after surgery. Scale ranges from a low of 40 (poor recovery) to a high of 200 (good recovery). (NCT01250002)
Timeframe: 24 hours post surgery
| Intervention | units on a scale (Median) |
|---|---|
| Group A (Study Group) Lidocaine | 175 |
| Placebo | 157.5 |
21 reviews available for celecoxib and Pain, Postoperative
| Article | Year |
|---|---|
Effectiveness of combined pregabalin and celecoxib for treatment of acute postoperative pain: A meta-analysis and systematic review.
Topics: Analgesics; Celecoxib; Humans; Narcotics; Pain, Postoperative; Pregabalin | 2022 |
The efficacy of celecoxib for pain management of arthroscopy: A meta-analysis of randomized controlled trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Celecoxib; Dose-Response Relationship, Drug; H | 2019 |
Analgesic effectiveness and safety of celecoxib versus non-opioid active controls after third molar surgery: A meta-analytical evaluation.
Topics: Analgesics; Celecoxib; Humans; Ibuprofen; Molar, Third; Nausea; Pain, Postoperative; Vomiting | 2022 |
Incidence of Heterotopic Ossification Following a Multimodal Pain Protocol in Total Hip Arthroplasty With the Posterior Approach.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, | 2018 |
Updates on Multimodal Analgesia for Orthopedic Surgery.
Topics: Acetaminophen; Amines; Analgesia; Celecoxib; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobut | 2018 |
Single dose oral celecoxib for acute postoperative pain in adults.
Topics: Acute Pain; Administration, Oral; Adult; Celecoxib; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhi | 2013 |
Preoperative celecoxib in noncardiac surgery: A systematic review and meta-analysis of randomised controlled trials.
Topics: Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Pain Measurement; Pain, Postoperative; Preoperative | 2016 |
Single dose oral celecoxib for acute postoperative pain in adults.
Topics: Administration, Oral; Celecoxib; Cyclooxygenase Inhibitors; Humans; Pain, Postoperative; Pyrazoles; | 2008 |
Postdischarge complications and rehabilitation after ambulatory surgery.
Topics: Ambulatory Surgical Procedures; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Automob | 2008 |
Single dose oral celecoxib for acute postoperative pain in adults.
Topics: Acute Pain; Administration, Oral; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Pain, Postoperativ | 2012 |
COX-2-selective inhibitors: clinical relevance in surgical and acute pain.
Topics: Acute Disease; Analgesics; Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cycloo | 2002 |
Single dose oral celecoxib for postoperative pain.
Topics: Celecoxib; Cyclooxygenase Inhibitors; Humans; Pain, Postoperative; Pyrazoles; Randomized Controlled | 2003 |
The burden of acute postoperative pain and the potential role of the COX-2-specific inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cost of Illness; Cyclooxygenase 2; Cyclooxygenas | 2003 |
Celecoxib, rofecoxib, and acute temporary visual impairment.
Topics: Acute Disease; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxy | 2003 |
[Clinical pharmacology of the selective COX-2 inhibitors].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis | 2003 |
A systematic review of COX-2 inhibitors compared with traditional NSAIDs, or different COX-2 inhibitors for post-operative pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Humans; Isoxazoles; L | 2004 |
[Cyclooxygenase-2 inhibitors in postoperative pain management].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Humans; Lactones; Pai | 2004 |
COX-2 inhibitors celecoxib and parecoxib: valuable options for postoperative pain management.
Topics: Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Pain, Postoperative; Pyrazoles; Sulfonam | 2007 |
Cyclooxygenase-2 specificity and its clinical implications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Celecoxib; Clinical Trial | 1999 |
COX-2 inhibitors and dental pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Contraindications; Cyclooxygenase Inhibitors; Fa | 1999 |
Potential role of the new specific COX-2 inhibitors in dermatologic surgery.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Humans; Pain | 2000 |
119 trials available for celecoxib and Pain, Postoperative
| Article | Year |
|---|---|
Efficacy and safety between early use and late use of celecoxib in hip osteoarthritis patients who receive total hip arthroplasty: a randomized, controlled study.
Topics: Aged; Arthroplasty, Replacement, Hip; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Humans; Male; | 2021 |
The analgesic effect and safety of preoperative versus postoperative administration of celecoxib in patients who underwent arthroscopic rotator cuff repair: a randomized, controlled study.
Topics: Analgesics; Arthroscopy; Celecoxib; Humans; Pain, Postoperative; Rotator Cuff; Treatment Outcome | 2022 |
High-Dose Celecoxib for Pain After Pediatric Tonsillectomy: A Randomized Controlled Trial.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Child; Double-Blind Me | 2023 |
Imrecoxib versus celecoxib as postoperative analgesia for patients receiving arthroscopic knee surgery: a randomized, controlled, non-inferiority study.
Topics: Analgesia; Celecoxib; Humans; Meperidine; Pain, Postoperative; Pyrroles; Sulfides | 2022 |
Celecoxib-tramadol co-crystal in patients with moderate-to-severe pain following bunionectomy with osteotomy: A phase 3, randomized, double-blind, factorial, active- and placebo-controlled trial.
Topics: Adult; Analgesics, Opioid; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Combina | 2023 |
HTX-011 in Combination with Multimodal Analgesic Regimen Minimized Severe Pain and Opioid Use after Total Knee Arthroplasty in an Open-Label Study.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; | 2023 |
Opioid-sparing pain management protocol after shoulder arthroplasty results in less opioid consumption and higher satisfaction: a prospective, randomized controlled trial.
Topics: Acetaminophen; Analgesics, Opioid; Arthroplasty, Replacement, Shoulder; Bupivacaine; Celecoxib; Gaba | 2022 |
Efficacy of Opioids in Preemptive Multimodal Analgesia for Total Knee Arthroplasty: A Prospective, Double-Blind, Placebo-Controlled, Randomized Trial.
Topics: Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Double-Blind Method; Humans; Morphin | 2023 |
Efficacy and safety of co-crystal of tramadol-celecoxib (CTC) in acute moderate-to-severe pain after abdominal hysterectomy: A randomized, double-blind, phase 3 trial (STARDOM2).
Topics: Acute Pain; Analgesics, Opioid; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Co | 2022 |
Positive Preemptive Analgesia Effectiveness of Pregabalin Combined with Celecoxib in Total Knee Arthroplasty: A Prospective Controlled Randomized Study.
Topics: Analgesia; Analgesics, Opioid; Arthroplasty, Replacement, Knee; C-Reactive Protein; Celecoxib; Doubl | 2023 |
Quality of recovery after pericapsular nerve group (PENG) block for primary total hip arthroplasty under spinal anaesthesia: a randomised controlled observer-blinded trial.
Topics: Acetaminophen; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Arthroplasty, Replacement | 2023 |
Multimodal analgesia did not improve post-operative pain scores, reduce opioid consumption or reduce length of stay following hip arthroscopy.
Topics: Analgesia; Analgesics, Opioid; Arthroscopy; Celecoxib; Gabapentin; Humans; Length of Stay; Pain, Pos | 2023 |
Postoperative analgesic efficacy and safety of imrecoxib versus celecoxib in hip osteoarthritis patients undergoing total hip arthroplasty: a multi-center, randomized, controlled, non-inferiority study.
Topics: Analgesics; Arthroplasty, Replacement, Hip; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Met | 2023 |
Oxycodone-acetaminophen versus celecoxib for postoperative pain in knee osteoarthritis patients after total knee arthroplasty: a randomized, controlled study.
Topics: Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Double-Blind Method; Hum | 2023 |
Efficacy of Adding Acetaminophen to Preemptive Multimodal Analgesia in Total Knee Arthroplasty: A Double-blinded Randomized Study.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Double-Bli | 2023 |
Intercostal block vs. epidural analgesia in thoracoscopic lung cancer surgery: a randomized trial.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics; Celecoxib; Female; Humans; Japan; Lung Neoplasms; Male | 2020 |
Efficacy of preemptive analgesia versus postoperative analgesia of celecoxib on postoperative pain, patients' global assessment and hip function recovery in femoroacetabular impingement patients underwent hip arthroscopy surgery.
Topics: Adult; Arthroscopy; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Femoracetabular Impingement; Hip | 2020 |
Comparison of Low Pre-Emptive Oral Doses of Celecoxib Versus Acetaminophen for Postoperative Pain Management After Third Molar Surgery: A Randomized Controlled Study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Celecoxib; Double-Blind Method; Humans; Molar, Third; Pain, | 2020 |
Postoperative intravenous parecoxib sodium followed by oral celecoxib post total knee arthroplasty in osteoarthritis patients (PIPFORCE): a multicentre, double-blind, randomised, placebo-controlled trial.
Topics: Administration, Intravenous; Administration, Oral; Aged; Arthroplasty, Replacement, Knee; Celecoxib; | 2020 |
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration | 2021 |
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration | 2021 |
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration | 2021 |
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration | 2021 |
Transdermal buprenorphine patch versus oral celecoxib for pain management after total knee arthroplasty: An open- label, randomized controlled trial.
Topics: Analgesics, Opioid; Arthroplasty, Replacement, Knee; Buprenorphine; Celecoxib; Humans; Pain Manageme | 2020 |
Oral tramadol versus oral celecoxib for analgesia after mediolateral episiotomy repair in obese primigravidae: a randomized controlled trial.
Topics: Analgesia; Analgesics, Opioid; Celecoxib; Double-Blind Method; Episiotomy; Female; Humans; Obesity; | 2021 |
Short-Term Effects of Early Postoperative Celecoxib Administration for Pain, Sleep Quality, and Range of Motion After Total Knee Arthroplasty: A Randomized Controlled Trial.
Topics: Arthroplasty, Replacement, Knee; Celecoxib; Double-Blind Method; Humans; Pain, Postoperative; Range | 2021 |
Celecoxib significantly reduces opioid use after shoulder arthroplasty.
Topics: Analgesics, Opioid; Arthroplasty; Arthroplasty, Replacement, Shoulder; Celecoxib; Humans; Pain Measu | 2021 |
A Multimodal Pain Management Regimen for Open Treatment of Distal Radius Fractures: A Randomized Blinded Study.
Topics: Acetaminophen; Analgesics, Opioid; Celecoxib; Humans; Narcotics; Oxycodone; Pain Management; Pain, P | 2022 |
Efficacy of celecoxib as preemptive analgesia for patients undergoing laparoscopic inguinal hernia repair: a randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia, General; Celecoxib; Diclofenac; Female; Herni | 2021 |
The analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block combined with oral multimodal analgesia in comparison with oral multimodal analgesia after caesarean delivery: a randomized controlled trial.
Topics: Abdominal Muscles; Acetaminophen; Administration, Oral; Adult; Analgesia, Obstetrical; Analgesics; C | 2021 |
Addition of Celebrex and Pregabalin to Ropivacaine for Posterior Spinal Surgery: A Randomized, Double-Blinded, Placebo-Controlled Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Celecoxib; Dose-Response Relationshi | 2021 |
Efficiency and safety: comparison between preoperative analgesia and postoperative analgesia using non-steroidal anti-inflammatory drugs in patients receiving arthroscopic knee surgery in a multicenter, randomized, controlled study.
Topics: Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Celecoxib; Female; Humans; K | 2021 |
Oxycodone-paracetamol tablet exhibits increased analgesic efficacy for acute postoperative pain, higher satisfaction and comparable safety profiles compared with celecoxib in patients underwent arthroscopic knee surgery.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Ag | 2021 |
Efficacy and safety of single-dose DFN-15 for treatment of acute postsurgical dental pain: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Analgesics; Celecoxib; Double-Blind Method; Humans; Pain Measurement; Pain, Postoperative | 2022 |
Gabapentin Does Not Appear to Improve Postoperative Pain and Sleep Patterns in Patients Who Concomitantly Receive Regional Anesthesia for Lower Extremity Orthopedic Surgery: A Randomized Control Trial.
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Arthroplasty, Replacement; Celecoxib; Cyclohexanecarbox | 2017 |
Application of a buprenorphine transdermal patch for the perioperative analgesia in patients who underwent simple lumbar discectomy.
Topics: Administration, Cutaneous; Administration, Intravenous; Administration, Oral; Analgesics, Opioid; Bu | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
The efficacy and safety of early initiation of preoperative analgesia with celecoxib in patients underwent arthroscopic knee surgery: A randomized, controlled study.
Topics: Adult; Analgesia; Arthroscopy; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Adm | 2017 |
Effectiveness of celecoxib for pain relief and antipyresis in second trimester medical abortions with misoprostol: a randomized controlled trial.
Topics: Abortion, Therapeutic; Administration, Sublingual; Adult; Anti-Inflammatory Agents, Non-Steroidal; A | 2018 |
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Celecoxib; Cyclooxygenase | 2018 |
[EFFICACY OF SEQUENTIAL TREATMENT WITH ADDUCTOR CANAL NERVE BLOCK AND CYCLOOXYGENASE 2 SELECTIVE INHIBITOR AFTER TOTAL KNEE ARTHROPLASTY].
Topics: Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; | 2016 |
Co-crystal of Tramadol-Celecoxib in Patients with Moderate to Severe Acute Post-surgical Oral Pain: A Dose-Finding, Randomised, Double-Blind, Placebo- and Active-Controlled, Multicentre, Phase II Trial.
Topics: Adult; Analgesics, Opioid; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; | 2018 |
Celecoxib versus ketorolac following robotic hysterectomy for the management of postoperative pain: An open-label randomized control trial.
Topics: Activities of Daily Living; Administration, Intravenous; Administration, Oral; Adult; Aged; Analgesi | 2018 |
Preoperative celecoxib analgesia is more efficient and equally tolerated compared to postoperative celecoxib analgesia in knee osteoarthritis patients undergoing total knee arthroplasty: A randomized, controlled study.
Topics: Aged; Analgesia, Patient-Controlled; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacem | 2018 |
Comparative Analgesic Effects of Ibuprofen, Celecoxib and Tramadol after third Molar Surgery: A Randomized Double Blind Controlled Trial.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Double-Blind Meth | 2018 |
Evaluation of the efficacy of celecoxib and ibuprofen on postoperative pain, swelling, and mouth opening after surgical removal of impacted third molars: a randomized, controlled clinical trial.
Topics: Celecoxib; Double-Blind Method; Humans; Ibuprofen; Molar, Third; Pain, Postoperative; Tooth Extracti | 2019 |
Comparative analgesic efficacy and tolerability of celecoxib and tramadol on postoperative pain after mandibular third molar extraction: A double blind randomized controlled trial.
Topics: Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Double-Bl | 2019 |
Effects of combined application of muscle relaxants and celecoxib administration after total knee arthroplasty (TKA) on early recovery: a randomized, double-blind, controlled study.
Topics: Aged; Arthroplasty, Replacement, Knee; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; | 2013 |
Perioperative celecoxib decreases opioid use in patients undergoing testicular surgery: a randomized, double-blind, placebo controlled trial.
Topics: Adult; Analgesics, Opioid; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Humans; Male | 2013 |
The importance of communication in the management of postoperative pain.
Topics: Acetaminophen; Adult; Amines; Analgesics; Analgesics, Opioid; Celecoxib; Communication; Cyclohexanec | 2013 |
A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study.
Topics: Aged; Aged, 80 and over; Analgesics; Celecoxib; Decompression, Surgical; Drug Therapy, Combination; | 2013 |
A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study.
Topics: Aged; Aged, 80 and over; Analgesics; Celecoxib; Decompression, Surgical; Drug Therapy, Combination; | 2013 |
A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study.
Topics: Aged; Aged, 80 and over; Analgesics; Celecoxib; Decompression, Surgical; Drug Therapy, Combination; | 2013 |
A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study.
Topics: Aged; Aged, 80 and over; Analgesics; Celecoxib; Decompression, Surgical; Drug Therapy, Combination; | 2013 |
A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study.
Topics: Aged; Aged, 80 and over; Analgesics; Celecoxib; Decompression, Surgical; Drug Therapy, Combination; | 2013 |
A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study.
Topics: Aged; Aged, 80 and over; Analgesics; Celecoxib; Decompression, Surgical; Drug Therapy, Combination; | 2013 |
A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study.
Topics: Aged; Aged, 80 and over; Analgesics; Celecoxib; Decompression, Surgical; Drug Therapy, Combination; | 2013 |
A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study.
Topics: Aged; Aged, 80 and over; Analgesics; Celecoxib; Decompression, Surgical; Drug Therapy, Combination; | 2013 |
A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study.
Topics: Aged; Aged, 80 and over; Analgesics; Celecoxib; Decompression, Surgical; Drug Therapy, Combination; | 2013 |
Celecoxib as a pre-emptive analgesia after arthroscopic knee surgery; a triple-blinded randomized controlled trial.
Topics: Adult; Analgesia; Anterior Cruciate Ligament Reconstruction; Arthroscopy; Celecoxib; Cyclooxygenase | 2013 |
Efficacy of celecoxib for pain management after arthroscopic surgery of hip: a prospective randomized placebo-controlled study.
Topics: Adult; Analgesics, Opioid; Arthroscopy; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; | 2014 |
Indomethacin submicron particle capsules provide effective pain relief in patients with acute pain: a phase 3 study.
Topics: Acute Pain; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Celecoxib; C | 2013 |
Pre-emptive analgesia with pregabalin and celecoxib decreases postsurgical pain following maxillomandibular advancement surgery: a randomized controlled clinical trial.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Analgesia, Patient-Controlled; Analge | 2014 |
A parallel-group comparison study of celecoxib with loxoprofen sodium in third mandibular molar extraction patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Female | 2014 |
Celecoxib pharmacogenetics and pediatric adenotonsillectomy: a double-blinded randomized controlled study.
Topics: Adenoidectomy; Adolescent; Celecoxib; Child; Child, Preschool; Cyclooxygenase 2 Inhibitors; Cytochro | 2015 |
Loxoprofen sodium and celecoxib for postoperative pain in patients after spinal surgery: a randomized comparative study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relat | 2015 |
Effect of cyclooxygenase-2-specific inhibitors on postoperative analgesia after major open abdominal surgery.
Topics: Abdomen; Analgesia, Patient-Controlled; Analgesics, Opioid; Analysis of Variance; Celecoxib; Cycloox | 2015 |
Preemptive multimodal analgesia for postoperative pain management after lumbar fusion surgery: a randomized controlled trial.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Celecoxib; Delayed-Action Preparations; Drug Th | 2016 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
The effect of pregabalin and celecoxib on the analgesic requirements after laparoscopic cholecystectomy: a randomized controlled trial.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Celecoxib; Cholecystectomy, Laparoscopic; Double-Blind | 2016 |
Pregabalin reduces postoperative opioid consumption and pain for 1 week after hospital discharge, but does not affect function at 6 weeks or 3 months after total hip arthroplasty.
Topics: Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Replacement, H | 2015 |
Effects of postoperative administration of celecoxib on pain management in patients after total knee arthroplasty: study protocol for an open-label randomized controlled trial.
Topics: Arthroplasty, Replacement, Knee; Celecoxib; Clinical Protocols; Cyclooxygenase 2 Inhibitors; Data Co | 2016 |
COMPARISON OF PRE-EMPTIVE EFFECT OF MELOXICAM AND CELECOXCIB ON POST-OPERATIVE ANALGESIA: A DOUBLE-BLIND, RANDOMIZED CLINICAL TRIAL.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 In | 2015 |
Comparison of the effects of treatment with celecoxib, loxoprofen, and acetaminophen on postoperative acute pain after arthroscopic knee surgery: A randomized, parallel-group trial.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Non-Narcotic; Anterior Cruciate Ligament Injuries; Ant | 2016 |
Celecoxib Versus Placebo in Tonsillectomy: A Prospective, Randomized, Double-Blind Placebo-Controlled Trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Celecoxib; Chronic Disease; Cycl | 2016 |
Efficacy and safety of Postoperative Intravenous Parecoxib sodium Followed by ORal CElecoxib (PIPFORCE) post-total knee arthroplasty in patients with osteoarthritis: a study protocol for a multicentre, double-blind, parallel-group trial.
Topics: Administration, Oral; Arthroplasty, Replacement, Knee; Celecoxib; China; Cyclooxygenase 2 Inhibitors | 2016 |
Hyperalgesia and Persistent Pain after Breast Cancer Surgery: A Prospective Randomized Controlled Trial with Perioperative COX-2 Inhibition.
Topics: Adult; Aged; Breast Neoplasms; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; | 2016 |
Impact of celecoxib on inflammation during cancer surgery: a randomized clinical trial.
Topics: Aged; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Follow-Up Studies; Humans; Inflammation; Male; | 2017 |
Is celecoxib a useful adjunct in the treatment of post-tonsillectomy pain in the adult population? A randomised, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind M | 2017 |
Efficacy of Celecoxib for Early Postoperative Pain Management in Hip Arthroscopy: A Prospective Randomized Placebo-Controlled Study.
Topics: Adult; Arthroscopy; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Hip Joint; | 2017 |
Multimodal analgesia without parenteral narcotics for total knee arthroplasty.
Topics: Administration, Oral; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analge | 2008 |
Perioperative celecoxib administration for pain management after total knee arthroplasty - a randomized, controlled study.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Ar | 2008 |
Perioperative celecoxib administration for pain management after total knee arthroplasty - a randomized, controlled study.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Ar | 2008 |
Perioperative celecoxib administration for pain management after total knee arthroplasty - a randomized, controlled study.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Ar | 2008 |
Perioperative celecoxib administration for pain management after total knee arthroplasty - a randomized, controlled study.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Ar | 2008 |
[Postoperative analgesia after laparoscopic cholecystectomy: comparison of the preoperative administration of celecoxib with paracetamol?].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 2008 |
[Effects of perioperative administration of celecoxib on pain management and recovery of function after total knee replacement].
Topics: Aged; Arthroplasty, Replacement, Knee; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Humans; Male; | 2009 |
Clinical trial: the impact of cyclooxygenase inhibitors on gastrointestinal recovery after major surgery - a randomized double blind controlled trial of celecoxib or diclofenac vs. placebo.
Topics: Adult; Aged; Aged, 80 and over; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Metho | 2009 |
[Multimodal effect of celecoxib on the perioperative analgesia in orthopaedic surgery].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; Celec | 2009 |
Acute pain after total hip arthroplasty does not predict the development of chronic postsurgical pain 6 months later.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Arthroplasty, Replacement, Hip; Celecoxib; Ch | 2010 |
Effect of celecoxib combined with thoracic epidural analgesia on pain after thoracotomy.
Topics: Administration, Oral; Adult; Aged; Analgesia, Epidural; Celecoxib; Cyclooxygenase 2 Inhibitors; Doub | 2010 |
The post-operative analgesic efficacy of celecoxib compared with placebo and parecoxib after total hip or knee arthroplasty.
Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesia; Arthroplasty, Replacement, Hip; Arthroplas | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Comparing etoricoxib and celecoxib for preemptive analgesia for acute postoperative pain in patients undergoing arthroscopic anterior cruciate ligament reconstruction: a randomized controlled trial.
Topics: Adolescent; Adult; Analgesia; Arthroscopy; Celecoxib; Cyclooxygenase 2 Inhibitors; Etoricoxib; Femal | 2010 |
Comparing etoricoxib and celecoxib for preemptive analgesia for acute postoperative pain in patients undergoing arthroscopic anterior cruciate ligament reconstruction: a randomized controlled trial.
Topics: Adolescent; Adult; Analgesia; Arthroscopy; Celecoxib; Cyclooxygenase 2 Inhibitors; Etoricoxib; Femal | 2010 |
Comparing etoricoxib and celecoxib for preemptive analgesia for acute postoperative pain in patients undergoing arthroscopic anterior cruciate ligament reconstruction: a randomized controlled trial.
Topics: Adolescent; Adult; Analgesia; Arthroscopy; Celecoxib; Cyclooxygenase 2 Inhibitors; Etoricoxib; Femal | 2010 |
Comparing etoricoxib and celecoxib for preemptive analgesia for acute postoperative pain in patients undergoing arthroscopic anterior cruciate ligament reconstruction: a randomized controlled trial.
Topics: Adolescent; Adult; Analgesia; Arthroscopy; Celecoxib; Cyclooxygenase 2 Inhibitors; Etoricoxib; Femal | 2010 |
The effects of oral ibuprofen and celecoxib in preventing pain, improving recovery outcomes and patient satisfaction after ambulatory surgery.
Topics: Activities of Daily Living; Administration, Oral; Adult; Ambulatory Surgical Procedures; Analgesics, | 2011 |
Multimodal analgesic approach incorporating paravertebral blocks for open radical retropubic prostatectomy: a randomized double-blind placebo-controlled study.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics; Celecoxib; Double-Blind M | 2011 |
The use of etoricoxib and celecoxib for pain prevention after periodontal surgery: a double-masked, parallel-group, placebo-controlled, randomized clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Celecoxib; Chronic Periodontitis; Cycloo | 2011 |
[Effect of cycloxygenase 2 inhibitor on levels of prostaglandin E2 in plasma and in local infiltrated fluid after functional endoscopic sinus surgery].
Topics: Adolescent; Adult; Celecoxib; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endoscopy; Female; Humans; | 2011 |
High-volume infiltration analgesia in bilateral hip arthroplasty. A randomized, double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Amides; Amines; Analgesics; Anesthesia, Local; Anesthetics, Local; A | 2011 |
Comparison of different loading dose of celecoxib on postoperative anti-inflammation and analgesia in patients undergoing endoscopic nasal surgery-200 mg is equivalent to 400 mg.
Topics: Adult; Celecoxib; Cyclooxygenase 2 Inhibitors; Endoscopy; Female; Humans; Inflammation; Male; Middle | 2011 |
Efficacy and safety of additional 200-mg dose of celecoxib in adult patients with postoperative pain following extraction of impacted third mandibular molar: a multicenter, randomized, double-blind, placebo-controlled, phase II study in Japan.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind | 2012 |
Preemptive analgesic effect of low doses of celecoxib is superior to low doses of traditional nonsteroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; C | 2012 |
A phase 2 study evaluating the efficacy and safety of a novel, proprietary, nano-formulated, lower dose oral diclofenac.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Diclofenac; Double-Blind Meth | 2012 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesic | 2013 |
In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model.
Topics: Adult; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinopros | 2002 |
Efficacy and tolerability of nonprescription ibuprofen versus celecoxib for dental pain.
Topics: Adolescent; Adult; Celecoxib; Dosage Forms; Double-Blind Method; Drug Administration Schedule; Femal | 2002 |
A comparison of rofecoxib versus celecoxib in treating pain after dental surgery: a single-center, randomized, double-blind, placebo- and active-comparator-controlled, parallel-group, single-dose study using the dental impaction pain model.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitor | 2002 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
The efficacy of celecoxib premedication on postoperative pain and recovery times after ambulatory surgery: a dose-ranging study.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Period; Anesthe | 2003 |
Preoperative oral celecoxib versus preoperative oral rofecoxib for pain relief after thyroid surgery.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Blood Pres | 2003 |
Effect of celecoxib and dexamethasone on postoperative pain after lumbar disc surgery.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; C | 2003 |
[Bupivacaine for continuous interscalene brachial plexus analgesia after shoulder surgery].
Topics: Adolescent; Adult; Aged; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Br | 2004 |
Analgesic efficacy of a single dose of lumiracoxib compared with rofecoxib, celecoxib and placebo in the treatment of post-operative dental pain.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Di | 2004 |
The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Antipruritics; Celecoxib; Ce | 2004 |
Celecoxib and ketoprofen for pain management during tonsillectomy: a placebo-controlled clinical trial.
Topics: Adolescent; Adult; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Follow-Up Studies; Hum | 2005 |
Preoperative use of selective COX-II inhibitors for pain management in laparoscopic nissen fundoplication.
Topics: Adult; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Female; Fundoplicati | 2005 |
COX-2 inhibitors and pain after oral surgery - pertinent papers 2002-2003.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitor | 2006 |
The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia; Anxiety; Breast Neoplasms; Bupivacaine; Celecoxib; Chronic Di | 2006 |
The analgesic efficacy of celecoxib, pregabalin, and their combination for spinal fusion surgery.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Celecoxib; Dose-Response Relationship, Drug; Doubl | 2006 |
The use of celecoxib and dexamethasone for the prevention and control of postoperative pain after periodontal surgery.
Topics: Adult; Anti-Inflammatory Agents; Celecoxib; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Dexamet | 2006 |
Effect of short-term postoperative celecoxib administration on patient outcome after outpatient laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Double-Bl | 2007 |
A randomized, double-blind, celecoxib- and placebo-controlled study of the effectiveness of CS-706 in acute postoperative dental pain.
Topics: Acute Disease; Adolescent; Adult; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship | 2007 |
Evaluating the analgesic efficacy of administering celecoxib as a component of multimodal analgesia for outpatient anterior cruciate ligament reconstruction surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesia; Anterior Cruciate Ligament; Anterior Cruciate Liga | 2007 |
Obturator versus femoral nerve block for analgesia after total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, | 2007 |
Lumiracoxib 400 mg compared with celecoxib 400 mg and placebo for treating pain following dental surgery: a randomized, controlled trial.
Topics: Adolescent; Adult; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Admin | 2008 |
Effects of celecoxib on blood loss, pain, and recovery of function after total knee replacement: a randomized placebo-controlled trial.
Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; | 2007 |
Analgesic efficacy of celecoxib in postoperative oral surgery pain: a single-dose, two-center, randomized, double-blind, active- and placebo-controlled study.
Topics: Adult; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Male; Middle Age | 2007 |
Perioperative versus postoperative celecoxib on patient outcomes after major plastic surgery procedures.
Topics: Activities of Daily Living; Adult; Analgesics, Opioid; Celecoxib; Cyclooxygenase 2 Inhibitors; Defec | 2008 |
Does celecoxib have pre-emptive analgesic effect after Caesarean section surgery?
Topics: Analgesia, Obstetrical; Celecoxib; Cesarean Section; Cyclooxygenase 2 Inhibitors; Double-Blind Metho | 2008 |
Comparison of rofecoxib and celecoxib, two cyclooxygenase-2 inhibitors, in postoperative dental pain: a randomized, placebo- and active-comparator-controlled clinical trial.
Topics: Adult; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Enzyme Inhibitors; Female; Humans; | 1999 |
Postoperative analgesic effects of celecoxib or rofecoxib after spinal fusion surgery.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; C | 2000 |
Efficacy and tolerability of celecoxib versus hydrocodone/acetaminophen in the treatment of pain after ambulatory orthopedic surgery in adults.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; | 2001 |
The efficacy of premedication with celecoxib and acetaminophen in preventing pain after otolaryngologic surgery.
Topics: Acetaminophen; Adenoids; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents | 2002 |
52 other studies available for celecoxib and Pain, Postoperative
| Article | Year |
|---|---|
Enhanced Recovery after Surgery Protocol to Improve Racial and Ethnic Disparities in Postcesarean Pain Management.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Celecoxib; Endrin; Enhanced | 2022 |
Single-dose premedication enhances multimodal analgesia after knee arthroplasty.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Dexam | 2023 |
Tramadol/celecoxib (Seglentis) for pain.
Topics: Analgesics, Opioid; Celecoxib; Humans; Hydrocodone; Oxycodone; Pain; Pain, Postoperative; Tramadol | 2022 |
Preemptive multimodal analgesia and post-operative pain outcomes in total hip and total knee arthroplasty.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacem | 2023 |
Comparison of in vivo behaviors of intramuscularly long-acting celecoxib nanosuspensions with different particle sizes for the postoperative pain treatment.
Topics: Acute Pain; Analgesics; Animals; Celecoxib; Nanoparticles; Pain, Postoperative; Particle Size; Rats | 2023 |
Opioid-Free Discharge After Pancreatic Resection Through a Learning Health System Paradigm.
Topics: Acetaminophen; Adult; Aftercare; Aged; Analgesics, Opioid; Celecoxib; Cohort Studies; Female; Humans | 2023 |
How We Do It: Postoperative Pain Control in Mohs Micrographic Surgery.
Topics: Acetaminophen; Aged; Analgesics; Anesthesia, Local; Anesthetics, Local; Breakthrough Pain; Celecoxib | 2021 |
A comprehensive model for pain management in patients undergoing pelvic reconstructive surgery: a prospective clinical practice study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2020 |
Perioperative Outcomes of Patients Who Were Not Candidates for Additional Nonsteroidal Anti-inflammatory Drugs in a Multimodal Pain Control Regimen for Total Knee Arthroplasty.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Ar | 2021 |
Bilateral Breast Reduction Without Opioid Analgesics: A Comparative Study.
Topics: Adult; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthesia, Local; | 2017 |
Preemptive analgesia by using celecoxib combined with tramadol/APAP alleviates post-operative pain of patients undergoing total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacem | 2017 |
The efficacy of a multimodal analgesia protocol in preventing heterotopic ossification after acetabular fractures surgery.
Topics: Acetabulum; Adult; Aged; Analgesia; Celecoxib; Combined Modality Therapy; Cyclooxygenase 2 Inhibitor | 2017 |
Perioperative Celecoxib and Postoperative Opioid Use in Hand Surgery: A Prospective Cohort Study.
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, | 2018 |
Preoperative pain measures ineffective in outpatient abdominal surgeries.
Topics: Abdomen; Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Anti-Inflammatory Agents, Non-St | 2018 |
Transition to Nonopioid Analgesia Does Not Impair Pain Control After Major Aesthetic Plastic Surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anticonvulsants; Celecoxib; Cyclooxygenase 2 Inhibit | 2018 |
Association of Celecoxib Use With Decreased Opioid Requirements After Head and Neck Cancer Surgery With Free Tissue Reconstruction.
Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Female; Free Tissue Fl | 2018 |
Letter Regarding "Perioperative Celecoxib and Postoperative Opioid Use in Hand Surgery: A Prospective Cohort Study".
Topics: Celecoxib; Humans; Pain, Postoperative; Postoperative Period; Prospective Studies | 2018 |
Response to "Letter Regarding 'Perioperative Celecoxib and Postoperative Opioid Use in Hand Surgery: A Prospective Cohort Study'".
Topics: Celecoxib; Cohort Studies; Humans; Pain, Postoperative; Postoperative Period; Prospective Studies | 2018 |
A Comparison of Analgesic Effect between Loxoprofen and Celecoxib and the Frequency of the Hemorrhage Following Tonsillectomy.
Topics: Adult; Analgesics; Celecoxib; Female; Hemorrhage; Humans; Male; Pain, Postoperative; Phenylpropionat | 2016 |
Comparison of perioperative flurbiprofen axetil or celecoxib administration for pain management after total-knee arthroplasty: A retrospective study.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Ar | 2018 |
Multimodal Postoperative Pain Control Is Effective and Reduces Opioid Use After Laparoscopic Roux-en-Y Gastric Bypass.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics, Opioid; Breakthrough Pain; Celecoxib; | 2019 |
Danger of highlighting the use of coxibs in daily dental practice.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; | 2019 |
In response to Letter to the Editor "Danger of highlighting the use of coxibs in daily dental practice".
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; | 2019 |
Preoperative multimodal analgesia decreases 24-hour postoperative narcotic consumption in elective spinal fusion patients.
Topics: Adult; Aged; Analgesia; Analgesics; Analgesics, Opioid; Celecoxib; Drug Therapy, Combination; Electi | 2019 |
Multimodal analgesia therapy reduces length of hospitalization in patients undergoing fusions of the ankle and hindfoot.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2013 |
[Unexpected hemorrhage complications in association with celecoxib. Spontaneously reported case series after perioperative pain treatment in gynecological operations].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Drug Overdose; Female; Gynecologic Surgical Proc | 2014 |
Evaluation of Celecoxib Addition to Pain Protocol After Total Hip and Knee Arthroplasty Stratified by Opioid Tolerance.
Topics: Aged; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Cyclooxygenase 2 Inhibitors; D | 2015 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Acute pain Factors predictive of post-operative pain and opioid requirement in multimodal analgesia following knee replacement.
Topics: Acute Pain; Aged; Amides; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anxiety; Arthroplasty, | 2016 |
A comparison between fentanyl plus celecoxib therapy and epidural anesthesia for postoperative pain management following laparoscopic gastrectomy.
Topics: Administration, Oral; Aged; Anesthesia, Epidural; Anesthetics, Intravenous; Celecoxib; Cyclooxygenas | 2016 |
Utilization of a Preemptive, Multimodal Analgesic Regimen in Adult Ambulatory Septoplasty Patients: A Quality Improvement Project.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Amines; Analgesics; Celecoxib; Cyclohexanecarb | 2015 |
Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection.
Topics: Administration, Oral; Aged; Aged, 80 and over; Analgesia; Anesthesia, Epidural; Celecoxib; Colectomy | 2017 |
Analgesic efficacy of celecoxib in patients after oral surgery: special reference to time to onset of analgesia and duration of analgesic effect.
Topics: Adult; Analgesics; Celecoxib; Female; Humans; Male; Mandible; Middle Aged; Molar, Third; Oral Surgic | 2016 |
The Administration of Celecoxib as an Analgesic after Liver Resection Is Safe.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Celecoxib; Female; Gast | 2017 |
The first 6 weeks of recovery after primary total hip arthroplasty with fast track.
Topics: Acetaminophen; Activities of Daily Living; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Proce | 2017 |
[Postoperative inconveniences after breast cancer surgery].
Topics: Acetaminophen; Amines; Analgesics; Antiemetics; Antitussive Agents; Breast Neoplasms; Celecoxib; Cyc | 2008 |
[Multimodal treatment of pain and nausea in breast cancer surgery].
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Antiemetics; Antitussive Agents; Breast Neoplasm | 2008 |
Combined preoperative use of celecoxib and gabapentin in the management of postoperative pain.
Topics: Administration, Oral; Adult; Amines; Analgesics, Opioid; Breast Implantation; Celecoxib; Cohort Stud | 2009 |
A prospective evaluation of 2 different pain management protocols for total hip arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Arthroplasty, Replacement, | 2010 |
Preemptive multimodal pain regimen reduces opioid analgesia for patients undergoing robotic-assisted laparoscopic radical prostatectomy.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; C | 2010 |
Current and innovative pain management techniques in total knee arthroplasty.
Topics: Anesthesia, Conduction; Arthroplasty, Replacement, Knee; Celecoxib; Clinical Protocols; Cyclooxygena | 2012 |
Retrospective evaluation of inpatient celecoxib use after total hip and knee arthroplasty at a Veterans Affairs Medical Center.
Topics: Administration, Oral; Aged; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replac | 2012 |
Pharmacological characterisation of a rat model of incisional pain.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Disease Model | 2004 |
Preemptive analgesia by zaltoprofen that inhibits bradykinin action and cyclooxygenase in a post-operative pain model.
Topics: Administration, Oral; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Brad | 2005 |
The safety of the perioperative administration of cyclooxygenase-2 inhibitors for post-surgical pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty; Blood Loss, Surgical; Celecoxib; Child; Cyclo | 2005 |
High dose nonsteroidal anti-inflammatory drugs compromise spinal fusion.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Female; Humans; Ketorolac; Lactones | 2005 |
Prolonged cholestasis associated with short-term use of celecoxib.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cholestasis; Female; Humans; Jaundice, Ob | 2005 |
Interpleural analgesia in breast reconstruction.
Topics: Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupiv | 2008 |
TTX-R Na+ current-reduction by celecoxib correlates with changes in PGE(2) and CGRP within rat DRG neurons during acute incisional pain.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Calcitonin Gene-Related Peptide; Celec | 2008 |
A new class of COX-2 inhibitors offer an alternative to NSAIDS in pain management after spinal surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; C | 2001 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac | 2001 |
[Cox-2 inhibitors in the focus. Rofecoxib as effective as the "classics"].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2001 |