Page last updated: 2024-10-24

celecoxib and Pain, Chronic

celecoxib has been researched along with Pain, Chronic in 19 studies

Research Excerpts

ExcerptRelevanceReference
"To investigate whether respectively radial extracoporeal shock wave therapy (rESWT) or a combination of rESWT, celecoxib and eperisone (rESWT + C + E) are superior in reducing pain in patients with chronic nonspecific low back pain (cnsLBP) compared to C + E alone (a standard treatment of this condition in China)."9.41Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial. ( Feng, Z; Guo, X; Li, L; Li, Y; Peng, Z; Schmitz, C; Yan, Z; Yang, Y; Zhang, Y, 2021)
"The aim of this study was to examine the cost-effectiveness of branded and authorized generic (AG) celecoxib for chronic pain patients with osteoarthritis (OA), rheumatoid arthritis (RA), and low back pain (LBP), using real-world cost information for loxoprofen and pharmacotherapy for gastrointestinal bleeding."8.02Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan. ( Kamae, I; Karasawa, Y; Murata, T; Nozawa, K; Sakamoto, C; Soen, S; Zeniya, S, 2021)
"Pregabalin in the context of multimodal pain management may be associated with reduced opioid consumption and other medical complications in patients undergoing TKA, including previous users of chronic pain medications."7.80Pregabalin reduces opioid consumption and improves outcome in chronic pain patients undergoing total knee arthroplasty. ( Chen, AF; Hozack, WJ; Parvizi, J; Sawan, H; Viscusi, ER, 2014)
"In patients with chronic pain, oral analgesics are essential treatment options to manage pain appropriately, improve activities of daily living abilities and achieve a higher quality of life (QOL)."7.30Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee. ( Aono, H; Endo, M; Hara, T; Kawahara, S; Kawano, T; Mawatari, T; Miyaji, T; Miyake, M; Nakashima, Y; Sakamoto, S; Sato, T; Shimokawa, M; Takano, T; Tokunaga, M; Zenda, S, 2023)
"Chronic low back pain is a common clinical problem in both the human and canine population."6.87Intradiscal application of a PCLA-PEG-PCLA hydrogel loaded with celecoxib for the treatment of back pain in canines: What's in it for humans? ( Beukers, M; Bos, C; Creemers, LB; de Leeuw, M; Grinwis, GCM; Meij, BP; Plomp, SGM; Tellegen, AR; Tryfonidou, MA; van Dijk, M; Willems, N, 2018)
" There was no significant difference in the incidence of adverse events (AEs), SAEs, and discontinuations due to AEs; however, the incidence of gastrointestinal AEs in OA patients treatment with celecoxib is significantly higher than that with placebo."6.53Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. ( Gu, K; Hou, Y; Xu, C; Yasen, Y, 2016)
"Tramadol-acetaminophen was effective at reducing chronic LBP and conferred a prophylactic motivational effect in patients with chronic LBP."5.43Effect of Tramadol/Acetaminophen on Motivation in Patients with Chronic Low Back Pain. ( Nishida, K; Ozaki, T; Takei, Y; Tanaka, M; Tetsunaga, T, 2016)
"To investigate whether respectively radial extracoporeal shock wave therapy (rESWT) or a combination of rESWT, celecoxib and eperisone (rESWT + C + E) are superior in reducing pain in patients with chronic nonspecific low back pain (cnsLBP) compared to C + E alone (a standard treatment of this condition in China)."5.41Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial. ( Feng, Z; Guo, X; Li, L; Li, Y; Peng, Z; Schmitz, C; Yan, Z; Yang, Y; Zhang, Y, 2021)
"Celecoxib is frequently prescribed to treat knee osteoarthritis (KOA), but how celecoxib influences the activity of the central nervous system to alleviate chronic pain remains unclear."5.30Cerebral mechanism of celecoxib for treating knee pain: study protocol for a randomized controlled parallel trial. ( Chen, Y; Cheng, S; Dong, X; He, W; Huang, Y; Li, Z; Liang, F; Sheng, Y; Tang, C; Wu, X; Yin, B; Zeng, F; Zhou, J, 2019)
"We know from adult randomised controlled trials that some NSAIDs, such as ibuprofen, naproxen, and aspirin, can be effective in certain chronic pain conditions."4.95Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. ( Anderson, B; Cooper, TE; Eccleston, C; Fisher, E; Wilkinson, NM, 2017)
"The aim of this study was to examine the cost-effectiveness of branded and authorized generic (AG) celecoxib for chronic pain patients with osteoarthritis (OA), rheumatoid arthritis (RA), and low back pain (LBP), using real-world cost information for loxoprofen and pharmacotherapy for gastrointestinal bleeding."4.02Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan. ( Kamae, I; Karasawa, Y; Murata, T; Nozawa, K; Sakamoto, C; Soen, S; Zeniya, S, 2021)
" Pelvic pain had developed in EAP rats, which was attenuated by a single treatment with celecoxib or pregabalin, suggesting that EAP is an appropriate model for prostatitis-related pain."3.88Chronic pelvic pain and prostate inflammation in rat experimental autoimmune prostatitis: Effect of a single treatment with phosphodiesterase 5 inhibitors on chronic pelvic pain. ( Kotera, T; Kurita, M; Oka, M; Okamoto, K; Yamaguchi, H, 2018)
"Pregabalin in the context of multimodal pain management may be associated with reduced opioid consumption and other medical complications in patients undergoing TKA, including previous users of chronic pain medications."3.80Pregabalin reduces opioid consumption and improves outcome in chronic pain patients undergoing total knee arthroplasty. ( Chen, AF; Hozack, WJ; Parvizi, J; Sawan, H; Viscusi, ER, 2014)
"In patients with chronic pain, oral analgesics are essential treatment options to manage pain appropriately, improve activities of daily living abilities and achieve a higher quality of life (QOL)."3.30Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee. ( Aono, H; Endo, M; Hara, T; Kawahara, S; Kawano, T; Mawatari, T; Miyaji, T; Miyake, M; Nakashima, Y; Sakamoto, S; Sato, T; Shimokawa, M; Takano, T; Tokunaga, M; Zenda, S, 2023)
"Chronic low back pain is a common clinical problem in both the human and canine population."2.87Intradiscal application of a PCLA-PEG-PCLA hydrogel loaded with celecoxib for the treatment of back pain in canines: What's in it for humans? ( Beukers, M; Bos, C; Creemers, LB; de Leeuw, M; Grinwis, GCM; Meij, BP; Plomp, SGM; Tellegen, AR; Tryfonidou, MA; van Dijk, M; Willems, N, 2018)
"Chronic pain is associated with impaired regulation of cardiovascular and analgesia systems, which may predispose to persistent BP elevation."2.82The Effects of Pain and Analgesic Medications on Blood Pressure. ( Coscarelli, A; Giordano, A; Menale, S; Rivasi, G; Turrin, G; Ungar, A, 2022)
" There was no significant difference in the incidence of adverse events (AEs), SAEs, and discontinuations due to AEs; however, the incidence of gastrointestinal AEs in OA patients treatment with celecoxib is significantly higher than that with placebo."2.53Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. ( Gu, K; Hou, Y; Xu, C; Yasen, Y, 2016)
" For older adult patients at higher risk for NSAID-related adverse effects, such as those who have gastrointestinal or cardiovascular disease, diabetes mellitus, or who are taking low-dose aspirin, opioids are recommended instead."2.49Opioids for chronic pain: new evidence, new strategies, safe prescribing. ( de Leon-Casasola, OA, 2013)
"Tramadol-acetaminophen was effective at reducing chronic LBP and conferred a prophylactic motivational effect in patients with chronic LBP."1.43Effect of Tramadol/Acetaminophen on Motivation in Patients with Chronic Low Back Pain. ( Nishida, K; Ozaki, T; Takei, Y; Tanaka, M; Tetsunaga, T, 2016)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's13 (68.42)24.3611
2020's6 (31.58)2.80

Authors

AuthorsStudies
Guo, X1
Li, L1
Yan, Z1
Li, Y2
Peng, Z1
Yang, Y1
Zhang, Y1
Schmitz, C1
Feng, Z1
Rivasi, G1
Menale, S1
Turrin, G1
Coscarelli, A1
Giordano, A1
Ungar, A1
Xu, H1
Zhao, C1
Guo, G1
A, X1
Qiu, G1
Wang, Y1
Kang, B1
Xu, X1
Xie, J1
Xiao, L1
Antonen, EG1
Kruchek, MM1
Nikitina, MV1
Endo, M1
Kawahara, S1
Sato, T1
Tokunaga, M1
Hara, T1
Mawatari, T1
Kawano, T1
Zenda, S1
Miyaji, T1
Shimokawa, M1
Sakamoto, S1
Takano, T1
Miyake, M1
Aono, H1
Nakashima, Y1
Karasawa, Y1
Kamae, I1
Nozawa, K1
Zeniya, S1
Murata, T1
Soen, S1
Sakamoto, C1
Tellegen, AR1
Willems, N1
Beukers, M1
Grinwis, GCM1
Plomp, SGM1
Bos, C1
van Dijk, M1
de Leeuw, M1
Creemers, LB1
Tryfonidou, MA1
Meij, BP1
Eccleston, C1
Cooper, TE1
Fisher, E1
Anderson, B1
Wilkinson, NM1
Kurita, M1
Yamaguchi, H1
Okamoto, K1
Kotera, T1
Oka, M1
Tang, C1
Dong, X1
He, W1
Cheng, S1
Chen, Y1
Huang, Y1
Yin, B1
Sheng, Y1
Zhou, J1
Wu, X1
Zeng, F1
Li, Z1
Liang, F1
Lee, JY2
Choi, HY1
Park, CS1
Jang, C1
Lee, KT1
Youn, I1
Yune, TY1
de Leon-Casasola, OA1
Sawan, H1
Chen, AF1
Viscusi, ER1
Parvizi, J1
Hozack, WJ1
Danilov, AB1
Grigorenko, NV1
Laux-Biehlmann, A1
Boyken, J1
Dahllöf, H1
Schmidt, N1
Zollner, TM1
Nagel, J1
Xu, C1
Gu, K1
Yasen, Y1
Hou, Y1
Tetsunaga, T2
Tanaka, M1
Nishida, K1
Takei, Y1
Ozaki, T1
Rastogi, R1
Swarm, RA1
Patel, TA1
Robinson, I1
Sargent, B1
Hatcher, JP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Randomized, Controlled, Single Centre Trial to Assess the Efficacy and Safety of Radial Extracorporeal Shock Wave Therapy in Patients With Chronic Non-specific Low Back Pain[NCT03337607]150 participants (Anticipated)Interventional2017-11-13Recruiting
Comparative Effects of Shockwave Therapy and Maitland's Lumbar Mobilization on Pain, Disability and Range of Motion in Patients With Mechanical Low Back Pain[NCT05404997]26 participants (Anticipated)Interventional2022-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for celecoxib and Pain, Chronic

ArticleYear
The Effects of Pain and Analgesic Medications on Blood Pressure.
    Current hypertension reports, 2022, Volume: 24, Issue:10

    Topics: Acetaminophen; Adrenergic Agents; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ster

2022
Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents.
    The Cochrane database of systematic reviews, 2017, 08-02, Volume: 8

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Rheumatoid; Asp

2017
Opioids for chronic pain: new evidence, new strategies, safe prescribing.
    The American journal of medicine, 2013, Volume: 126, Issue:3 Suppl 1

    Topics: Age Factors; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chronic Pain; C

2013
[An antinociceptive effect of chondroprotectors: a myth or a reality?].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:9

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; C-Reactive Protein; Celecoxib; Chondroitin Sulf

2015
Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials.
    Medicine, 2016, Volume: 95, Issue:20

    Topics: Abdominal Pain; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Diarrhea; Dyspepsia; Headache;

2016
Case scenario: opioid association with serotonin syndrome: implications to the practitioners.
    Anesthesiology, 2011, Volume: 115, Issue:6

    Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhi

2011

Trials

5 trials available for celecoxib and Pain, Chronic

ArticleYear
Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial.
    Journal of orthopaedic surgery and research, 2021, Dec-04, Volume: 16, Issue:1

    Topics: Celecoxib; Chronic Pain; Extracorporeal Shockwave Therapy; Humans; Low Back Pain; Propiophenones; Pr

2021
Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial.
    Journal of orthopaedic surgery and research, 2021, Dec-04, Volume: 16, Issue:1

    Topics: Celecoxib; Chronic Pain; Extracorporeal Shockwave Therapy; Humans; Low Back Pain; Propiophenones; Pr

2021
Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial.
    Journal of orthopaedic surgery and research, 2021, Dec-04, Volume: 16, Issue:1

    Topics: Celecoxib; Chronic Pain; Extracorporeal Shockwave Therapy; Humans; Low Back Pain; Propiophenones; Pr

2021
Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial.
    Journal of orthopaedic surgery and research, 2021, Dec-04, Volume: 16, Issue:1

    Topics: Celecoxib; Chronic Pain; Extracorporeal Shockwave Therapy; Humans; Low Back Pain; Propiophenones; Pr

2021
The Effectiveness of Tuina in Relieving Pain, Negative Emotions, and Disability in Knee Osteoarthritis: A Randomized Controlled Trial.
    Pain medicine (Malden, Mass.), 2023, 03-01, Volume: 24, Issue:3

    Topics: Adult; Celecoxib; China; Chronic Pain; Emotions; Humans; Osteoarthritis, Knee; Treatment Outcome

2023
Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee.
    BMJ open, 2023, 02-10, Volume: 13, Issue:2

    Topics: Acetaminophen; Activities of Daily Living; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal

2023
Intradiscal application of a PCLA-PEG-PCLA hydrogel loaded with celecoxib for the treatment of back pain in canines: What's in it for humans?
    Journal of tissue engineering and regenerative medicine, 2018, Volume: 12, Issue:3

    Topics: Animals; Back Pain; Biocompatible Materials; Celecoxib; Chronic Pain; Cyclooxygenase 2; Dogs; Extrac

2018
Cerebral mechanism of celecoxib for treating knee pain: study protocol for a randomized controlled parallel trial.
    Trials, 2019, Jan-16, Volume: 20, Issue:1

    Topics: Adult; Arthralgia; Brain; Brain Mapping; Celecoxib; China; Chronic Pain; Cyclooxygenase 2 Inhibitors

2019

Other Studies

8 other studies available for celecoxib and Pain, Chronic

ArticleYear
[Evaluation of the effectiveness of treatment of patients with nonspecific pain syndrome in the lower back with celecoxib and a combined preparation of B vitamins].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2022, Volume: 122, Issue:8

    Topics: Adult; Celecoxib; Chronic Pain; Female; Humans; Low Back Pain; Male; Meloxicam; Middle Aged; Pain Me

2022
Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan.
    PloS one, 2021, Volume: 16, Issue:7

    Topics: Aged; Aged, 80 and over; Celecoxib; Chronic Pain; Computer Simulation; Cost Savings; Cost-Benefit An

2021
Chronic pelvic pain and prostate inflammation in rat experimental autoimmune prostatitis: Effect of a single treatment with phosphodiesterase 5 inhibitors on chronic pelvic pain.
    The Prostate, 2018, Volume: 78, Issue:15

    Topics: Analgesics; Animals; Autoimmune Diseases; Celecoxib; Chemokines; Chronic Pain; Cytokines; Disease Mo

2018
Inhibition of COX-2 alleviates lumbar spinal stenosis-induced chronic mechanical allodynia in rats.
    International immunopharmacology, 2019, Volume: 75

    Topics: Animals; Cauda Equina; Celecoxib; Chronic Pain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytok

2019
Pregabalin reduces opioid consumption and improves outcome in chronic pain patients undergoing total knee arthroplasty.
    The Physician and sportsmedicine, 2014, Volume: 42, Issue:2

    Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Chr

2014
Dynamic weight bearing as a non-reflexive method for the measurement of abdominal pain in mice.
    European journal of pain (London, England), 2016, Volume: 20, Issue:5

    Topics: Abdominal Pain; Aniline Compounds; Animals; Behavior, Animal; Celecoxib; Chronic Pain; Cyclooxygenas

2016
Effect of Tramadol/Acetaminophen on Motivation in Patients with Chronic Low Back Pain.
    Pain research & management, 2016, Volume: 2016

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Apathy;

2016
Use of dynamic weight bearing as a novel end-point for the assessment of Freund's Complete Adjuvant induced hypersensitivity in mice.
    Neuroscience letters, 2012, Aug-30, Volume: 524, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Endpoint Dete

2012